List of works by Nico M Wulffraat

2.2 A phase II trial with canakinumab, a new IL-1beta blocking monoclonal antibody (ACZ885), to evaluate preliminary dosing, safety and efficacy profile in children with systemic Juvenile Idiopathic arthritis (sJIA).

scientific article published on 15 September 2008

2.5 Mesenchymal Stem Cell Therapy has significant clinical effect in proteoglycan induced arthritis

scientific article published on 15 September 2008

2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Coll

scientific article published on 28 August 2015

2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Coll

scientific article published on March 2016

2019 update of EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases

scientific article published on 14 August 2019

4.5 Defective phosphorylation of the interleukin 18 receptor beta-chain causes impaired NK cell function in systemic onset Juvenile Idiopathic Arthritis

scientific article published on 15 September 2008

A Common Functional Ability Score for Young People with Juvenile Idiopathic Arthritis

scientific article published on 14 April 2020

A clinical prediction model for estimating the risk of developing uveitis in patients with juvenile idiopathic arthritis

scientific article published on 04 December 2020

A phase II, multicenter, open-label study evaluating dosing and preliminary safety and efficacy of canakinumab in systemic juvenile idiopathic arthritis with active systemic features.

scientific article

A randomized trial of parenteral methotrexate comparing an intermediate dose with a higher dose in children with juvenile idiopathic arthritis who failed to respond to standard doses of methotrexate

scientific article published on 01 July 2004

A randomized, placebo-controlled trial of infliximab plus methotrexate for the treatment of polyarticular-course juvenile rheumatoid arthritis

scientific article published on 01 September 2007

A safety evaluation of canakinumab for the treatment of systemic onset juvenile idiopathic arthritis

scientific article

A survey of national and multi-national registries and cohort studies in juvenile idiopathic arthritis: challenges and opportunities

scientific article

A three minute- screening tool for temporomandibular joint involvement in children with juvenile idiopathic arthritis

scientific article

ABCB1 and ABCC3 gene polymorphisms are associated with first-year response to methotrexate in juvenile idiopathic arthritis

scientific article

Addendum: proposed guidelines for autologous stem cell transplantation in juvenile chronic arthritis. Paediatric Rheumatology Workshop

scientific article published on 01 August 1999

Adverse events of methotrexate treatment in JIA.

scientific article published on 14 September 2011

Aerobic capacity and disease activity in children, adolescents and young adults with juvenile idiopathic arthritis (JIA).

scientific article published on 20 August 2012

Aerobic capacity and disease activity in children, adolescents and young adults with juvenile idiopathic arthritis (JIA).

scientific article published on 27 August 2012

Akinra restores the defective IL-18 NK cell axis in steroid naïve systemic onset JIA patients.

scientific article

An amino acid motif in HLA-DRβ1 distinguishes patients with uveitis in juvenile idiopathic arthritis.

scientific article published on 7 March 2018

Anakinra for flares of pyogenic arthritis in PAPA syndrome

scientific article published on 05 January 2005

Anakinra in mutation-negative NOMID/CINCA syndrome: comment on the articles by Hawkins et al and Hoffman and Patel

scientific article published on 01 November 2004

Anti-tumor necrosis factor α targets protein kinase B/c-Akt-induced resistance of effector cells to suppression in juvenile idiopathic arthritis

scientific article

Antibody deficiency in patients with ataxia telangiectasia is caused by disturbed B- and T-cell homeostasis and reduced immune repertoire diversity.

scientific article published on 6 April 2013

Assessment of disease activity by patients with juvenile idiopathic arthritis and the parents compared to the assessment by pediatric rheumatologists

scientific article published on 24 December 2013

Ataxia-telangiectasia patients presenting with hyper-IgM syndrome.

scientific article published on 17 February 2009

Atypical juvenile generalized scleroderma presenting as polyarthritis and failure to thrive

scientific article published on 01 February 1998

Autologous bone marrow transplantation in autoimmune arthritis restores immune homeostasis through CD4+CD25+Foxp3+ regulatory T cells

scientific article published on 06 February 2008

Autologous hematopoietic stem cell transplantation for autoimmune diseases

scientific article published on 01 May 2005

Autologous hemopoietic stem-cell transplantation for children with refractory autoimmune disease

scientific article

Autologous stem cell transplantation aids autoimmune patients by functional renewal and TCR diversification of regulatory T cells.

scientific article

Autologous stem cell transplantation for autoimmunity induces immunologic self-tolerance by reprogramming autoreactive T cells and restoring the CD4+CD25+ immune regulatory network

scientific article published in November 2005

Autologous stem cell transplantation for refractory juvenile idiopathic arthritis: analysis of clinical effects, mortality, and transplant related morbidity

scientific article published on October 2004

Autologous stem cell transplantation for refractory juvenile idiopathic artrhitis: current results and perspectives

scientific article published on 01 November 2002

Autologous stem cell transplantation for systemic lupus erythematosus

scientific article published on 01 January 2004

Autologous stem cell transplantation in children with severe progressive systemic or polyarticular juvenile idiopathic arthritis: long-term follow-up of a prospective clinical trial

scientific article published on 01 July 2007

Autologous stem cell transplantation leads to a change in proinflammatory plasma cytokine profile of patients with juvenile dermatomyositis correlating with disease activity

scientific article published on 30 September 2014

Autologous stem cell transplantation: a possible treatment for refractory juvenile chronic arthritis?

scientific article published on 01 August 1999

Autologous stem cell transplantation: an alternative for refractory juvenile chronic arthritis

scientific article published on 01 August 1999

Awareness of Fabry disease among rheumatologists--current status and perspectives

scientific article published in April 2011

Barbara Ansell: a person ahead of her time

scientific article published on 24 April 2019

Biologic treatment of pediatric rheumatic diseases: are we spoilt for choice?

scientific article published on 01 January 2014

Biomarker profiling of steroid-resistant acute GVHD in patients after infusion of mesenchymal stromal cells.

scientific article published on 3 April 2015

Blau syndrome: cross-sectional data from a multicentre study of clinical, radiological and functional outcomes.

scientific article

Blood and synovial fluid cytokine signatures in patients with juvenile idiopathic arthritis: a cross-sectional study.

scientific article

Bone-marrow derived mesenchymal stromal cells infusion in therapy refractory juvenile idiopathic arthritis patients

scientific article published on 01 October 2019

Brief report: Autologous stem cell transplantation restores immune tolerance in experimental arthritis by renewal and modulation of the Teff cell compartment

scientific article

Canakinumab in patients with systemic juvenile idiopathic arthritis and active systemic features: results from the 5-year long-term extension of the phase III pivotal trials

scientific article published on 29 September 2018

Canakinumab in pediatric rheumatic diseases

scientific article published on 04 March 2013

Canakinumab treatment shows maintained efficacy in systemic juvenile idiopathic arthritis patients

scientific article published on 17 September 2014

Changing winds in refractory autoimmune disease in children: clearing the road for tolerance with cellular therapies

scientific article published on May 2012

Children and young people get rheumatic disease too

scientific article published on 23 November 2018

Children with fever peaks and bone and joint pain: systemic juvenile idiopathic arthritis or acute lymphoblastic leukemia after all?

scientific article published on August 2002

Clinical Juvenile Arthritis Disease Activity Score proves to be a useful tool in treat-to-target therapy in juvenile idiopathic arthritis

scientific article published on 14 November 2017

Clinical features of childhood granulomatosis with polyangiitis (wegener's granulomatosis)

scientific article

Clostridium difficile-associated reactive arthritis in two children

scientific article published on 01 January 2004

Consensus-based recommendations for the management of juvenile localised scleroderma

scientific article published on 02 March 2019

Consensus-based recommendations for the management of juvenile systemic sclerosis

scientific article published on 04 November 2020

Consensus-based recommendations for the management of uveitis associated with juvenile idiopathic arthritis: the SHARE initiative

scientific article published on 28 March 2018

Costs of medication use among patients with juvenile idiopathic arthritis in the Dutch healthcare system

scientific article published on 26 November 2020

Current perspectives of autologous stem cell transplantation for severe Juvenile Idiopathic Arthritis

scientific article published on 01 December 2008

Cutaneous granulomas in ataxia telangiectasia and other primary immunodeficiencies: reflection of inappropriate immune regulation?

scientific article published on 26 August 2011

Cyclosporine A in juvenile idiopathic arthritis. Results of the PRCSG/PRINTO phase IV post marketing surveillance study.

scientific article published on September 2006

Defective phosphorylation of interleukin-18 receptor beta causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis.

scientific article

Deficiency of the beta subunit of the eighth component of complement presenting as arthritis and exanthem

scientific article published on 01 November 1994

Defining criteria for high disease activity in juvenile idiopathic arthritis based on the juvenile arthritis disease activity score.

scientific article published on 17 December 2013

Defining criteria for macrophage activation syndrome, a process towards early recognition and treatment

scientific article published on 01 April 2011

Delayed clinical response in patients with juvenile idiopathic arthritis treated with etanercept.

scientific article published on 15 January 2010

Design and acceptance of Rheumates@Work, a combined internet-based and in person instruction model, an interactive, educational, and cognitive behavioral program for children with juvenile idiopathic arthritis

scientific article

Development and validation of a prognostic multivariable model to predict insufficient clinical response to methotrexate in rheumatoid arthritis

scientific article published in PLoS ONE

Development of a standardized method of assessment of radiographs and radiographic change in juvenile idiopathic arthritis: introduction of the Dijkstra composite score

scientific article

Development of inflammatory bowel disease in patients with juvenile idiopathic arthritis treated with etanercept

scientific article

Development of new classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.

scientific article

Diagnostic workup for mixed connective tissue disease in childhood.

scientific article published on August 2008

Differences in persistence of measles, mumps, rubella, diphtheria and tetanus antibodies between children with rheumatic disease and healthy controls: a retrospective cross-sectional study

scientific article published on 15 December 2011

Disease activity and dropout in young persons with juvenile idiopathic arthritis in transition of care: a longitudinal observational study

scientific article published on 31 January 2018

Do snapshot statistics fool us in MTX pharmacogenetic studies in arthritis research?

scientific article published on 27 January 2010

Dr. de Rotte, et al reply

scientific article published in April 2013

Dutch juvenile idiopathic arthritis patients, carers and clinicians create a research agenda together following the James Lind Alliance method: a study protocol

scientific article published on 15 September 2018

EULAR recommendations for vaccination in adult patients with autoimmune inflammatory rheumatic diseases

scientific article published on 03 December 2010

EULAR recommendations for vaccination in paediatric patients with rheumatic diseases

scientific article published on 03 August 2011

Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy

scientific article published on 23 January 2017

Early effects of Anakinra in corticosteroid naïve SOJIA patients

scientific article (publication date: 2008)

Early predictors of prognosis in juvenile idiopathic arthritis patients: a systematic literature review.

scientific article published on 17 September 2014

Early predictors of prognosis in juvenile idiopathic arthritis: a systematic literature review

scientific article published on 24 June 2014

Educational initiatives and training for paediatric rheumatology in Europe

scientific article published on 07 December 2018

Effectiveness and safety of a second and third biological agent after failing etanercept in juvenile idiopathic arthritis: results from the Dutch National ABC Register

scientific article published on 23 June 2012

Effectiveness of first-line treatment with recombinant interleukin-1 receptor antagonist in steroid-naive patients with new-onset systemic juvenile idiopathic arthritis: results of a prospective cohort study.

scientific article published in April 2014

Effects of ACTH and ACTH fragments on DNA synthesis in guinea-pig adrenal segments kept in organ culture.

scientific article published in December 1987

Effects of sulfasalazine treatment on serum immunoglobulin levels in children with juvenile chronic arthritis

scientific article

Effects of the live attenuated measles-mumps-rubella booster vaccination on disease activity in patients with juvenile idiopathic arthritis: a randomized trial

scientific article published on June 2013

Efficacy and Safety of Canakinumab in sJIA Patients with and without Fever at Baseline: Results from an Open-label, Active Treatment Extension Study

scientific article published on 10 July 2020

Efficacy and safety of canakinumab, a long acting fully human anti-Interleukin-1β antibody, in systemic juvenile idiopathic arthritis with active systemic features: results from a phase III study

Efficacy and safety of open-label etanercept on extended oligoarticular juvenile idiopathic arthritis, enthesitis-related arthritis and psoriatic arthritis: part 1 (week 12) of the CLIPPER study

scientific article

Efficacy and safety of tocilizumab (TCZ) in patients with systemic juvenile idiopathic arthritis (SJIA): tender 52-week data.

scientific article

Efficacy and safety of tocilizumab (TCZ) in patients with systemic juvenile idiopathic arthritis (sJIA): TENDER 52-week data.

scientific article

Efficacy, immunogenicity and safety of vaccination in adult patients with autoimmune inflammatory rheumatic diseases: a systematic literature review for the 2019 update of EULAR recommendations

scientific article published on 09 September 2019

Epstein-Barr virus-associated haemophagocytic lympho-histiocytosis after stem cell transplantation.

scientific article published on 2 October 2006

Erythrocyte sedimentation rate as baseline predictor for the development of uveitis in children with juvenile idiopathic arthritis

scientific article published on 07 November 2014

Etanercept in juvenile idiopathic arthritis: Who will benefit?

Etanercept treatment for extended oligoarticular juvenile idiopathic arthritis, enthesitis-related arthritis, or psoriatic arthritis: 6-year efficacy and safety data from an open-label trial

European consensus-based recommendations for diagnosis and treatment of immunoglobulin A vasculitis-the SHARE initiative.

scientific article published on 16 March 2019

European consensus-based recommendations for the diagnosis and treatment of Kawasaki disease - the SHARE initiative

scientific article published on 01 April 2019

European consensus-based recommendations for the diagnosis and treatment of rare paediatric vasculitides - the SHARE initiative

scientific article published on 01 April 2020

European consensus-based recommendations for the diagnosis and treatment of rare paediatric vasculitides - the SHARE initiative

scientific article published on 01 April 2019

European evidence-based recommendations for diagnosis and treatment of childhood-onset systemic lupus erythematosus: the SHARE initiative.

scientific article published on 19 June 2017

European evidence-based recommendations for diagnosis and treatment of paediatric antiphospholipid syndrome: the SHARE initiative.

scientific article published on 4 May 2017

European evidence-based recommendations for the diagnosis and treatment of childhood-onset lupus nephritis: the SHARE initiative

scientific article published on 6 September 2017

Evidence based recommendations for diagnosis and management of mevalonate kinase defiency (MKD).

scientific article

Evidence based recommendations for diagnosis and treatment of cryopyrin-associated periodic syndromes (CAPS).

scientific article published on 17 September 2014

Evidence based recommendations for diagnosis and treatment of tumor necrosis factor receptor-1 associated periodic syndrome (TRAPS).

scientific article published on 17 September 2014

Evidence based recommendations for genetic diagnosis of Familial Mediterranean Fever

scientific article published on 17 September 2014

Evidence-based diagnosis and treatment of macrophage activation syndrome in systemic juvenile idiopathic arthritis

scientific article

Evidence-based recommendations for genetic diagnosis of familial Mediterranean fever

scientific article published on 27 January 2015

Evolution, trends, outcomes, and economics of hematopoietic stem cell transplantation in severe autoimmune diseases

scientific article published on 20 December 2017

Exercise tolerance in children with juvenile idiopathic arthritis after autologous SCT

scientific article published on 30 June 2008

Expert consensus on dynamics of laboratory tests for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.

scientific article published on 19 January 2016

Expression of myeloid-related proteins 8 and 14 in systemic-onset juvenile rheumatoid arthritis

scientific article published on 01 September 2003

Factors associated with treatment response to etanercept in juvenile idiopathic arthritis

scientific article published on 6 November 2011

Familial Cushing's syndrome due to primary pigmented nodular adrenocortical disease. Reinvestigation 50 years later

scientific article published on 01 December 1989

Fatal hemophagocytic lymphohistiocytosis in X-linked chronic granulomatous disease associated with a perforin gene variant

scientific article

Fatigue in childhood chronic disease

scientific article published on 07 June 2019

Fatigue in patients with Juvenile Idiopathic Arthritis: relationship to perceived health, physical health, self-efficacy, and participation

scientific article published on 06 December 2016

Functional alpha 1-adrenergic receptors on leukocytes of patients with polyarticular juvenile rheumatoid arthritis

scientific article published on 01 December 1996

Functional consequences of perforin gene mutations in 22 patients with familial haemophagocytic lymphohistiocytosis

article

General information for patients and carers considering haematopoietic stem cell transplantation (HSCT) for severe autoimmune diseases (ADs): A position statement from the EBMT Autoimmune Diseases Working Party (ADWP), the EBMT Nurses Group, the EBM

scientific article published on 31 January 2019

HPV infection and vaccination in Systemic Lupus Erythematosus patients: what we really should know

scientific article

Haematopoietic cell transplantation (HCT) in combination with enzyme replacement therapy (ERT) in patients with Hurler syndrome.

scientific article published on 22 May 2006

Haematopoietic stem cell transplantation for autoimmune diseases

scientific article

Health related quality of life measure in systemic pediatric rheumatic diseases and its translation to different languages: an international collaboration

scientific article

Hemophagocytosis during fludarabine-based SCT for systemic juvenile idiopathic arthritis

scientific article published on 12 June 2006

High prevalence of methotrexate intolerance in juvenile idiopathic arthritis: Development and validation of a methotrexate intolerance severity score

article

IL-1 receptor antagonist restores IL-18 NK cell axis in systemic JIA

scientific article

Identical mutations in RAG1 or RAG2 genes leading to defective V(D)J recombinase activity can cause either T-B-severe combined immune deficiency or Omenn syndrome

article

Immunogenicity and safety of the bivalent HPV vaccine in female patients with juvenile idiopathic arthritis: a prospective controlled observational cohort study

scientific article published on 30 May 2013

Immunogenicity of the bivalent human papillomavirus vaccine in adolescents with juvenile systemic lupus erythematosus or juvenile dermatomyositis

scientific article

Immunoglobulins of patients with Cushing's syndrome due to pigmented adrenocortical micronodular dysplasia stimulate in vitro steroidogenesis

scientific article

Immunoglobulins of patients with idiopathic Addison's disease block the in vitro action of adrenocorticotropin

scientific article published in August 1989

Immunology in the medical practice.XXXII. Transplantation of autologous hematopoietic stem cells for treatment of refractory auto-immune diseases; preliminary favorable results with 35 patients

scientific article published on 01 August 2000

Immunomodulatory actions of methotrexate on T cells in juvenile idiopathic arthritis

Immunomodulatory properties of mesenchymal stem cells: a review based on an interdisciplinary meeting held at the Kennedy Institute of Rheumatology Division, London, UK, 31 October 2005

scientific article published on January 2007

Incidence and prevalence of vaccine preventable infections in adult patients with autoimmune inflammatory rheumatic diseases (AIIRD): a systemic literature review informing the 2019 update of the EULAR recommendations for vaccination in adult patien

scientific article published on 19 September 2019

Internet Program for Physical Activity and Exercise Capacity in Children With Juvenile Idiopathic Arthritis: A Multicenter Randomized Controlled Trial.

scientific article published on October 2016

Interpretation of the Juvenile Arthritis Disease Activity Score: responsiveness, clinically important differences and levels of disease activity in prospective cohorts of patients with juvenile idiopathic arthritis.

scientific article published on 24 October 2013

Intolerance in oral versus subcutaneous administration of methotrexate in patients with juvenile idiopathic arthritis: a cross-sectional, observational study.

scientific article published on 17 September 2014

Joint contractures in the absence of inflammation may indicate mucopolysaccharidosis

scientific article published on 23 October 2009

Kinetics of the long-term antibody response after meningococcal C vaccination in patients with juvenile idiopathic arthritis: a retrospective cohort study

scientific article published on 16 March 2013

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

scientific article (publication date: 17 October 2003)

Live attenuated MMR/V booster vaccines in children with rheumatic diseases on immunosuppressive therapy are safe: Multicenter, retrospective data collection

scientific article published on 24 January 2020

Long term efficacy and safety of canakinumab in children with systemic juvenile idiopathic arthritis with and without fever.

scientific article

Long-term follow-up of autologous stem cell transplantation for refractory juvenile idiopathic arthritis.

scientific article published in August 2003

Long-term follow-up on effectiveness and safety of etanercept in juvenile idiopathic arthritis: the Dutch national register

scientific article published on 15 April 2008

Long-term outcome following hematopoietic stem-cell transplantation in Wiskott-Aldrich syndrome: collaborative study of the European Society for Immunodeficiencies and European Group for Blood and Marrow Transplantation

scientific article published on 27 September 2007

Long-term outcome of Hurler syndrome patients after hematopoietic cell transplantation: an international multicenter study.

scientific article published on 26 January 2015

Long-term outcome of juvenile idiopathic arthritis following a placebo-controlled trial: sustained benefits of early sulfasalazine treatment

scientific article

Maintenance of efficacy of canakinumab in SJIA at the individual patient level in a 12-week pooled dataset

scientific article published on 17 September 2014

Measles, Mumps, Rubella serology in juvenile idiopathic arthritis

scientific article published on 15 September 2008

Mesenchymal stem cell therapy in proteoglycan induced arthritis.

scientific article published on 6 January 2014

Mesenchymal stem cells and JIA.

scientific article

Mesenchymal stem cells: a future for the treatment of arthritis?

scientific article published on 16 June 2008

Mesenchymal stromal cells suppress synovial fluid-derived t cells from juvenile idiopathic arthritis patients in vitro

scientific article published on 17 September 2014

Methotrexate does not primarily affect Foxp3+ regulatory T cells in poly-articular juvenile idiopathic arthritis

scientific article published on 15 September 2008

Methotrexate improves the health-related quality of life of children with juvenile idiopathic arthritis.

scientific article published on 17 September 2007

Methotrexate in juvenile idiopathic arthritis: towards tailor-made treatment

scientific article published on 26 May 2014

Methotrexate intolerance in oral and subcutaneous administration in patients with juvenile idiopathic arthritis: a cross-sectional, observational study

scientific article published on 2 February 2016

Methotrexate polyglutamates in erythrocytes are associated with lower disease activity in juvenile idiopathic arthritis patients.

scientific article

Methotrexate polyglutamates in erythrocytes are associated with lower disease activity in patients with rheumatoid arthritis

scientific article published on 2 December 2013

Methotrexate restores effector T cell responsiveness in juvenile idiopathic arthritis

Methotrexate treatment affects effector but not regulatory T cells in juvenile idiopathic arthritis

scientific article published on 14 April 2015

Methotrexate withdrawal at 6 vs 12 months in juvenile idiopathic arthritis in remission: a randomized clinical trial

scientific article

Monitoring neutrophil activation in juvenile rheumatoid arthritis by S100A12 serum concentrations

scientific article published on April 2004

Munc13-4 is an effector of rab27a and controls secretion of lysosomes in hematopoietic cells

scientific article

Musculoskeletal manifestations of lysosomal storage disorders.

scientific article

Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome

scientific article (publication date: June 2000)

Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis.

scientific article

Myelodysplastic features in Griscelli syndrome

scientific article published on 01 May 2004

Myeloid related protein 8 and 14 secretion reflects phagocyte activation and correlates with disease activity in juvenile idiopathic arthritis treated with autologous stem cell transplantation

scientific article published on March 2003

Myeloid-related proteins 8 and 14 are specifically secreted during interaction of phagocytes and activated endothelium and are useful markers for monitoring disease activity in pauciarticular-onset juvenile rheumatoid arthritis

scientific article published on 01 March 2000

Nearly 20% of children are not correctly classified according to current ilar classification in a PRINTO dataset of more than 12,000 juvenile idiopathic arthritis patients.

scientific article published on 17 September 2014

Nonlethal transfusion associated graft-versus-host disease in a severe combined immunodeficient patient ⬇️

scientific article published on November 1, 2003

OR3-002 – Blau Syndrome cohort study: ocular outcome

scientific article

Opportunistic infections in immunosuppressed patients with juvenile idiopathic arthritis: analysis by the Pharmachild Safety Adjudication Committee

scientific article published on 07 April 2020

Outcome status in children with sustained polyarticular and systemic juvenile idiopathic arthritis

scientific article published on 01 February 2001

Outcomes of hematopoietic stem cell transplantation for Hurler's syndrome in Europe: a risk factor analysis for graft failure

scientific article published on 28 May 2007

PReS-FINAL-1015: A systematic literature review on diagnosis and treatment of pediatric rheumatic diseases: a shared initiative.

scientific article published on 5 December 2013

PReS-FINAL-2100: Methotrexate treatment affects effector, but not regulatory T cells in juvenile idiopathic arthritis.

scientific article published on 5 December 2013

PReS-FINAL-2107: In vitro investigation into mesenchymal stromal cells as a potential therapeutic in juvenile arthritis.

scientific article published on 5 December 2013

PReS-FINAL-2139: Tapering and withdrawal of tocilizumab in patients with systemic JIA in inactive disease: results from an alternative dosing regimen in the tender study.

scientific article

PReS-FINAL-2146: Trends in prescription of biologics and outcomes of juvenile idiopathic arthritis; results of the Dutch national arthritis and biologicals in children register.

scientific article published on 5 December 2013

PReS-FINAL-2147: Immunological consequences of biologicals in juvenile idiopathic arthritis.

scientific article

PReS-FINAL-2156: Analysis of gene expression and inflammation biomarkers in systemic juvenile idiopathic arthritis (SJIA) patients on canakinumab therapy.

scientific article published on 5 December 2013

PReS-FINAL-2158: Effect of canakinumab on functional ability and health-related quality of life in systemic juvenile idiopathic arthritis (SJIA) patients

scientific article published on 5 December 2013

PReS-FINAL-2162: Development of a risk model to predict methotrexate intolerance in juvenile idiopathic arthritis.

scientific article published on 5 December 2013

PReS-FINAL-2181: Recombinant il-1ra restores the il-18-nk cell axis in steroid naive systemic juvenile idiopathic arthritis.

scientific article published on 5 December 2013

PReS-FINAL-2184: A randomized trial in new onset juvenile dermatomyositis: prednisone versus prednisone plus cyclosporine versus prednisone plus methotrexate.

scientific article published on 5 December 2013

PReS-FINAL-2342: Anti-TNFALPHA therapy targeys PKB/C-AKT induced resistance of effector cells to suppression in juvenile arthritis

scientific article published on 5 December 2013

PW03-016 – Blau prospective cohort study: articular outcomes.

scientific article

Pathogenesis of juvenile idiopathic arthritis associated uveitis: the known and unknown

scientific article

Patient's experiences with the care for juvenile idiopathic arthritis across Europe.

scientific article published on 8 February 2018

Performance of Birmingham Vasculitis Activity Score and disease extent index in childhood vasculitides

scientific article published on 01 January 2012

Performance of current guidelines for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.

scientific article published in October 2014

Periodic fever as a presenting sign of childhood acute lymphoblastic leukaemia

scientific article published on 7 September 2005

Periodic fever in MVK deficiency: a patient initially diagnosed with incomplete Kawasaki disease

scientific article published on 27 January 2014

Phagocyte-specific S100 proteins and high-sensitivity C reactive protein as biomarkers for a risk-adapted treatment to maintain remission in juvenile idiopathic arthritis: a comparative study

scientific article published on 11 June 2012

Pharmacological conditioning for juvenile idiopathic arthritis: a potential solution to reduce methotrexate intolerance

scientific article published on 07 February 2020

Pharmacovigilance in juvenile idiopathic arthritis patients (Pharmachild) treated with biologic agents and/or methotrexate. Consolidated baseline characteristics from Pharmachild and other national registries

scientific article published on 17 September 2014

Pharmacovigilance in juvenile idiopathic arthritis patients treated with biologic or synthetic drugs: combined data of more than 15,000 patients from Pharmachild and national registries ⬇️

scientific article published on 27 December 2018

Phenotypic variability and disparities in treatment and outcomes of childhood arthritis throughout the world: an observational cohort study

scientific article published on 26 February 2019

Pneumococcal Vaccination Strategies in the Real World of Chronically Ill Patients

scientific article published on 01 February 2016

Point of view on the vaccination against COVID-19 in patients with autoimmune inflammatory rheumatic diseases

scientific article

Prediction of clinical non-response to methotrexate treatment in juvenile idiopathic arthritis

Prediction of clinical non-response to methotrexate treatment in juvenile idiopathic arthritis

scientific article published on 03 April 2012

Prediction of clinical non-response to methotrexate treatment in juvenile idiopathic arthritis.

scientific article published on 14 September 2011

Prediction of methotrexate efficacy and adverse events in patients with juvenile idiopathic arthritis: a systematic literature review

scientific article

Prediction of methotrexate efficacy and adverse events in patients with juvenile idiopathic arthritis: a systematic literature review.

scientific article published on 17 September 2014

Prediction of methotrexate intolerance in juvenile idiopathic arthritis: a prospective, observational cohort study

scientific article

Prednisone versus prednisone plus ciclosporin versus prednisone plus methotrexate in new-onset juvenile dermatomyositis: a randomised trial

scientific article

Presence of ATM protein and residual kinase activity correlates with the phenotype in ataxia-telangiectasia: a genotype-phenotype study

scientific article published on 25 January 2012

Prevalence of Severe Fatigue Among Adolescents With Pediatric Rheumatic Diseases

scientific article published on 28 August 2015

Prevalence of methotrexate intolerance in rheumatoid arthritis and psoriatic arthritis

scientific article published on January 2013

Primary Hypertrophic Osteoarthropathy: An Update on Patient Features and Treatment. ⬇️

scientific article published in November 2015

Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part one

article

Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part three: Genoa, Italy. 28 September – 01 October 2016.

scientific article published on 30 May 2017

Proceedings of the 23rd Paediatric Rheumatology European Society Congress: part two: Genoa, Italy. 28 September – 01 October 2016.

scientific article published on 30 May 2017

Prolonged remission without treatment after autologous stem cell transplantation for refractory childhood systemic lupus erythematosus

scientific article published on 01 March 2001

Proxy-reported health-related quality of life of patients with juvenile idiopathic arthritis: The pediatric rheumatology international trials organization multinational quality of life cohort study

article

Psychological side effects of MTX treatment in juvenile idiopathic arthritis: a pilot study.

scientific article published in May 2007

Puberty and disease activity in JIA.

scientific article published on 17 September 2014

Pulmonary hypertension and other potentially fatal pulmonary complications in systemic juvenile idiopathic arthritis

scientific article published on May 2013

Radiologic features in juvenile idiopathic arthritis: a first step in the development of a standardized assessment method

scientific article

Randomized trial of tocilizumab in systemic juvenile idiopathic arthritis

scientific article published on December 2012

Recombinant IL1-RA in the early phase of systemic onset JIA: before the onset of arthritis

Recommendations for collaborative paediatric research including biobanking in Europe: a Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) initiative

scientific article published on 11 October 2017

Recommendations for the management of autoinflammatory diseases.

scientific article published on 24 June 2015

Recommendations for the management of autoinflammatory diseases.

scientific article

Recurrent and opportunistic infections in children with primary intestinal lymphangiectasia

scientific article published on 01 March 2007

Reduced perforin expression in systemic juvenile idiopathic arthritis is restored by autologous stem-cell transplantation

scientific article published on 01 February 2003

Refractory juvenile idiopathic arthritis: using autologous stem cell transplantation as a treatment strategy

scientific article published on 15 November 2006

Regulatory T cells in autologous stem cell transplantation for autoimmune disease

scientific article published on December 2008

Response to: 'Bivalent HPV vaccine safety depending on subtypes of juvenile idiopathic arthritis' by Dr Akioka.

scientific article published on 29 September 2014

Restoration of the Immune Balance by Autologous Bone Marrow Transplantation in Juvenile Idiopathic Arthritis ⬇️

scientific article published on March 1, 2011

Reticular dysgenesis: international survey on clinical presentation, transplantation, and outcome

scientific article

S100A12 is a novel molecular marker differentiating systemic-onset juvenile idiopathic arthritis from other causes of fever of unknown origin

scientific article published on December 2008

SHARE – workpackage 5 : evidence based recommendations for diagnosis and treatment of childhood-onset systemic lupus erythematosus

scientific article published on 17 September 2014

SHARE – workpackage 5: development of best practices of diagnosis and treatment for paediatric rheumatic diseases throughout Europe.

scientific article published on 17 September 2014

SHARE – workpackage 5: evidence based recommendations for diagnosis and treatment of juvenile dermatomyositis.

scientific article published on 17 September 2014

SHARE – workpackage 5: evidence based recommendations for diagnosis and treatment of juvenile localized scleroderma and juvenile systemic sclerosis

scientific article published on 17 September 2014

SHARE – workpackage 5: evidence based recommendations for diagnosis and treatment of the antiphospholipid syndrome

scientific article published on 17 September 2014

SHARE – workpackage 5: evidence-based recommendations for diagnosis and treatment of kawasaki disease and henoch schönlein purpura.

scientific article published on 17 September 2014

Safety and efficacy of enzyme replacement therapy in combination with hematopoietic stem cell transplantation in Hurler syndrome

scientific article

Safety and efficacy of meningococcal c vaccination in juvenile idiopathic arthritis

scientific article published on 01 February 2007

Safety and immunogenicity of human papillomavirus vaccination in juvenile patients with rheumatic diseases

scientific article published on 14 September 2011

Safety and immunogenicity of the quadrivalent human papillomavirus vaccine in patients with childhood systemic lupus erythematosus: a real-world interventional multi-centre study

scientific article published on 05 June 2020

Safety and immunogenicity of the quadrivalent human papillomavirus vaccine in patients with juvenile dermatomyositis: a real-world multicentre study

scientific article published on 11 November 2020

Safety of anti-TNFalpha therapy in children with juvenile idiopathic arthritis.

scientific article published on March 2004

Safety of measles, mumps and rubella vaccination in juvenile idiopathic arthritis

scientific article published on 6 February 2007

Secondary autoimmune diseases occurring after HSCT for an autoimmune disease: a retrospective study of the EBMT Autoimmune Disease Working Party

scientific article

Seeking the state of the art in standardized measurement of health care resource use and costs in juvenile idiopathic arthritis: a scoping review

article

Share – Workpackage 4: addressing the need for health care for paediatric rheumatic diseases throughout europe

scientific article published on 17 September 2014

Share – Workpackage 5: evidence based recommendations for diagnosis and treatment of juvenile idiopathic arthritis.

scientific article published on 17 September 2014

Single-nucleotide polymorphisms in the folate pathway are associated with response to methotrexate treatment in juvenile idiopathic arthritis

scientific article published on 15 September 2008

Stem cell transplantation for autoimmune disorders. Refractory juvenile idiopathic arthritis

scientific article published in June 2004

Stem cells in pediatrics: state of the art and future perspectives

scientific article published in April 2012

Stress induces increases in IL-6 production by leucocytes of patients with the chronic inflammatory disease juvenile rheumatoid arthritis: a putative role for alpha(1)-adrenergic receptors

scientific article published on 01 October 2000

Successful cord blood transplantation in a premature and dysmature neonate of 1700 g with reticular dysgenesis

scientific article published on 29 January 2007

Sulfasalazine in the treatment of juvenile chronic arthritis: a randomized, double-blind, placebo-controlled, multicenter study. Dutch Juvenile Chronic Arthritis Study Group

scientific article published on 01 May 1998

Survival in a recent cohort of mechanically ventilated pediatric allogeneic hematopoietic stem cell transplantation recipients

scientific article published on 01 December 2008

Systemic juvenile idiopathic arthritis is associated with HLA-DRB1 in Europeans and Americans of European descent

scientific article

Tapering Canakinumab Monotherapy in Patients with Systemic Juvenile Idiopathic Arthritis in Clinical Remission: Results from an Open-label, Randomized Phase IIIb/IV Study

scientific article published on 11 August 2020

Tapering and withdrawal of tocilizumab in patients with systemic juvenile idiopathic arthritis in inactive disease: results from an alternative dosing regimen in the TENDER study

scientific article published on 17 September 2014

Temporomandibular joint involvement in Juvenile Idiopathic Arthritis: reliability and validity of a screening protocol for the rheumatologist

scientific article published on 7 May 2015

The Dutch version of the Childhood Health Assessment Questionnaire (CHAQ) and the Child Health Questionnaire (CHQ).

scientific article

The Dutch version of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR).

scientific article published on 7 April 2018

The European network for care of children with paediatric rheumatic diseases: care across borders

scientific article published on 01 July 2019

The International Consortium for Health Outcome Measurement (ICHOM)Set of Outcomes that Matter to People Living with Inflammatory Arthritis Consensus from an international Working Group

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The PRINTO criteria for clinically inactive disease in juvenile dermatomyositis

scientific article published on 26 June 2012

The PRINTO provisional definition of remission in juvenile dermatomyositis

The Paediatric Rheumatology International Trials Organisation provisional criteria for the evaluation of response to therapy in juvenile dermatomyositis

scientific article

The TLR4 ligands MRP8 and MRP14 in the diagnosis and pathogenesis of systemic onset juvenile idiopathic arthritis

scientific article published on 15 September 2008

The burden of systemic juvenile idiopathic arthritis for patients and caregivers: an international survey and retrospective chart review

The efficacy and safety of interleukin-1-receptor antagonist anakinra in the treatment of systemic juvenile idiopathic arthritis ⬇️

scientific article published on October 28, 2010

The evaluation of uveitis in juvenile idiopathic arthritis (JIA) patients: are current ophthalmologic screening guidelines adequate?

scientific article published in March 2008

The myeloid-related proteins 8 and 14 complex, a novel ligand of toll-like receptor 4, and interleukin-1beta form a positive feedback mechanism in systemic-onset juvenile idiopathic arthritis

scientific article published on March 2009

The patient and parent perspective on methotrexate in recent Juvenile Idiopathic Arthritis guidelines

scientific article published on 23 February 2020

The role of placebo effects in immune-related conditions: mechanisms and clinical considerations

scientific article published on 10 September 2018

The safety of live-attenuated vaccines in patients using IL-1 or IL-6 blockade: an international survey.

scientific article

The skin in primary immunodeficiency disorders.

scientific article

The value of old drugs for juvenile idiopathic arthritis.

scientific article

Time to share

scientific article published on 15 February 2013

Toward New Classification Criteria for Juvenile Idiopathic Arthritis: First Steps, Pediatric Rheumatology International Trials Organization International Consensus

scientific article published on 01 October 2018

Towards European harmonisation of healthcare for patients with rare immune disorders: outcome from the ERN RITA registries survey

scientific article published on 30 January 2020

Transition of rheumatologic care, from teenager to adult: which health assessment questionnaire can be best used?

scientific article published on March 2010

Transplantation of hematopoietic stem cells and long-term survival for primary immunodeficiencies in Europe: entering a new century, do we do better?

scientific article published on 31 July 2010

Treating juvenile idiopathic arthritis to target: recommendations of an international task force.

scientific article published on 11 April 2018

Treating juvenile idiopathic arthritis to target: what is the optimal target definition to reach all goals?

scientific article published on 16 April 2020

Treatment choices of paediatric rheumatologists for juvenile idiopathic arthritis: etanercept or adalimumab?

scientific article published on 4 June 2013

Treatment of CD40 ligand deficiency by hematopoietic stem cell transplantation: a survey of the European experience, 1993-2002

scientific article published on 02 October 2003

Treatment of chronic granulomatous disease with myeloablative conditioning and an unmodified hemopoietic allograft: a survey of the European experience, 1985-2000.

scientific article

Treatment of methotrexate (MTX) intolerance: behavioural therapy, versus switch to parenteral MTX versus oral MTX.

scientific article

Treatment of refractory juvenile idiopathic arthritis

scientific article published on 01 May 2001

Treatment to Target Using Recombinant Interleukin-1 Receptor Antagonist as First-Line Monotherapy in New-Onset Systemic Juvenile Idiopathic Arthritis: Results From a Five-Year Follow-Up Study

scientific article published on 25 May 2019

Trends in prescription of biological agents and outcomes of juvenile idiopathic arthritis: results of the Dutch national Arthritis and Biologics in Children Register

scientific article published on 18 March 2014

Tuberculosis in a nine-year-old girl treated with infliximab for systemic juvenile idiopathic arthritis

scientific article published in April 2004

Tumor necrosis factor-blocking agents for children with enthesitis-related arthritis--data from the dutch arthritis and biologicals in children register, 1999-2010.

scientific article

Tumour necrosis factor (TNF)-blocking agents in juvenile psoriatic arthritis: are they effective? ⬇️

scientific article published on November 10, 2010

Tumour necrosis factor-blocking agents in persistent oligoarticular juvenile idiopathic arthritis: results from the Dutch Arthritis and Biologicals in Children Register

scientific article published on 24 December 2012

Two genes are responsible for Griscelli syndrome at the same 15q21 locus.

scientific article

Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis

scientific article

Umbilical cord blood from an unrelated donor as source for stem cell transplantations in inborn errors of metabolism

scientific article published in August 2008

Use and perceived relevance of health-related Internet sites and online contact with peers among young people with juvenile idiopathic arthritis

scientific article published on 20 May 2015

Use of internet in adolescents and young adults with JIA.

scientific article published on 17 September 2014

Use of the JADAS criteria to assess efficacy of canakinumab in patients with SJIA – an analysis of 12-week pooled data

scientific article published on 17 September 2014

Using registries to identify adverse events in rheumatic diseases.

scientific article published on 21 October 2013

Vaccination in adult patients with auto-immune inflammatory rheumatic diseases: a systematic literature review for the European League Against Rheumatism evidence-based recommendations for vaccination in adult patients with auto-immune inflammatory

scientific article published on 20 December 2010

Vaccination in paediatric patients with auto-immune rheumatic diseases: a systemic literature review for the European League against Rheumatism evidence-based recommendations

scientific article published on 28 August 2011

Vaccination leads to an aberrant FOXP3 T-cell response in non-remitting juvenile idiopathic arthritis

scientific article published on 22 August 2011

Vaccinations in paediatric rheumatology: an update on current developments

scientific article published on July 2015

Validation of Relapse Risk Biomarkers for Routine Use in Patients With Juvenile Idiopathic Arthritis

scientific article published on 01 June 2014

Varicella vaccination elicits a humoral and cellular response in children with rheumatic diseases using immune suppressive treatment

scientific article published on 12 April 2017

What are the immunological consequences of long-term use of biological therapies for juvenile idiopathic arthritis?

scientific article

When and how to stop etanercept after successful treatment of patients with juvenile idiopathic arthritis

scientific article published on 01 July 2009

Whole Transcriptome Analysis Reveals Heterogeneity in B Cell Memory Populations in Patients With Juvenile Idiopathic Arthritis-Associated Uveitis

scientific article published on 17 September 2020

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