List of works - Daniel Schramek

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene

scientific article

A mouse model to identify cooperating signaling pathways in cancer

article

AIF-regulated oxidative phosphorylation supports lung cancer development

scientific article published on 27 May 2019

AJUBA: a regulator of epidermal homeostasis and cancer

scientific article published on 29 December 2020

Aberrant regulation of RANKL/OPG in women at high risk of developing breast cancer

scientific article published on 18 December 2016

Afatinib restrains K-RAS–driven lung tumorigenesis

scientific article published on 01 June 2018

Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy

scientific article published on 24 June 2019

CRISPR-Switch regulates sgRNA activity by Cre recombination for sequential editing of two loci

scientific article published on 29 November 2019

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer

scientific article published on 24 July 2020

Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis

scientific article

Disruption of the growth hormone--signal transducer and activator of transcription 5--insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis.

scientific article

Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate

scientific article

Forward and reverse genetics through derivation of haploid mouse embryonic stem cells.

scientific article published on December 2011

Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection

scientific article

In vivo CRISPR screens reveal potent driver mutations in head and neck cancers

scientific article published on 13 May 2020

Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer

scientific article

Overexpression of the oncogenic signal transducer Gab2 occurs early in breast cancer development

article

Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells.

scientific article published on 5 March 2013

RANKL and RANK in sex hormone-induced breast cancer and breast cancer metastasis

scientific article published on 04 April 2011

RANKL/RANK control Brca1 mutation-driven mammary tumors

scientific article published on 31 May 2016

RANKL/RANK-beyond bones

scientific article

Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling

scientific article published on 01 March 2020

The GATOR-Rag GTPase pathway inhibits mTORC1 activation by lysosome-derived amino acids

scientific article

The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression

scientific article published on 13 February 2011

Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 1: Late Recurrence: Current Understanding, Clinical Considerations

scientific article published on 10 August 2019

Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 2: Approaches to Predict and Identify Late Recurrence, Research Directions

scientific article published on 10 August 2019

List of works by Daniel Schramek

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene

A mouse model to identify cooperating signaling pathways in cancer

AIF-regulated oxidative phosphorylation supports lung cancer development

AJUBA: a regulator of epidermal homeostasis and cancer

Aberrant regulation of RANKL/OPG in women at high risk of developing breast cancer

Afatinib restrains K-RAS–driven lung tumorigenesis

Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy

CRISPR-Switch regulates sgRNA activity by Cre recombination for sequential editing of two loci

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer

Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis

Disruption of the growth hormone--signal transducer and activator of transcription 5--insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis.

Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate

Forward and reverse genetics through derivation of haploid mouse embryonic stem cells.

Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection

In vivo CRISPR screens reveal potent driver mutations in head and neck cancers

Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer

Overexpression of the oncogenic signal transducer Gab2 occurs early in breast cancer development

Progesterone drives mammary secretory differentiation via RankL-mediated induction of Elf5 in luminal progenitor cells.

RANKL and RANK in sex hormone-induced breast cancer and breast cancer metastasis

RANKL/RANK control Brca1 mutation-driven mammary tumors

RANKL/RANK-beyond bones

Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling

The GATOR-Rag GTPase pathway inhibits mTORC1 activation by lysosome-derived amino acids

The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression

Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 1: Late Recurrence: Current Understanding, Clinical Considerations

Toronto Workshop on Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Part 2: Approaches to Predict and Identify Late Recurrence, Research Directions