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List of works by Elke Jäger

A phase II study of alemtuzumab, fludarabine, cyclophosphamide, and doxorubicin (Campath-FCD) in peripheral T-cell lymphomas

scientific article

Acetylation of Stat1 modulates NF-kappaB activity

scientific article published on February 2006

Afatinib with concurrent radiotherapy in a patient with metastatic non-small cell lung cancer

scientific article

An open-label, phase I study of the polo-like kinase-1 inhibitor, BI 2536, in patients with advanced solid tumors

scientific article published on 3 August 2010

Antigen-specific immunotherapy and cancer vaccines

scientific article

CD4+ CD25+ regulatory T cells control the induction of antigen-specific CD4+ helper T cell responses in cancer patients

scientific article published on 19 April 2005

CD8(+) T cell responses against a dominant cryptic HLA-A2 epitope after NY-ESO-1 peptide immunization of cancer patients

scientific article

Cancer vaccine enhanced, non-tumor-reactive CD8(+) T cells exhibit a distinct molecular program associated with "division arrest anergy".

scientific article published on 12 May 2009

Cancer-related serological recognition of human colon cancer: identification of potential diagnostic and immunotherapeutic targets.

scientific article

Clinical cancer vaccine trials

scientific article

Clinically Relevant Immune Responses against Cytomegalovirus: Implications for Precision Medicine

article

Combination of Trastuzumab and Triple FLOT Chemotherapy (5-Fluorouracil/Leucovorin, Oxaliplatin, and Docetaxel) in Patients with HER2-Positive Metastatic Gastric Cancer: Report of 3 Cases ⬇️

scientific article published on August 17, 2012

Correction: Identification of neoepitopes recognized by tumor-infiltrating lymphocytes (TILs) from patients with glioma

Cross-presentation of HLA class I epitopes from exogenous NY-ESO-1 polypeptides by nonprofessional APCs

scientific article published on 01 February 2003

Cytokine Networks and Survivin Peptide-Specific Cellular Immune Responses Predict Improved Survival in Patients With Glioblastoma Multiforme

scientific article published on 29 June 2018

Detection of antigen-specific T-cells with MHC/peptide-tetramer-complexes

Distinct structural TCR repertoires in naturally occurring versus vaccine-induced CD8+ T-cell responses to the tumor-specific antigen NY-ESO-1

scientific article published on 01 May 2005

Efficacy of vaccination with recombinant vaccinia and fowlpox vectors expressing NY-ESO-1 antigen in ovarian cancer and melanoma patients

scientific article published on 27 March 2012

Efficient In vivo Priming by Vaccination with Recombinant NY-ESO-1 Protein and CpG in Antigen Naïve Prostate Cancer Patients ⬇️

scientific article published on December 16, 2010

Epitope clustering in regions undergoing efficient proteasomal processing defines immunodominant CTL regions of a tumor antigen

scientific article published on 24 October 2006

Expression of TAAs in glioblastoma and expansion of anti-TAA -reactive T cells

Focal progression in patients with gastrointestinal stromal tumors after initial response to imatinib mesylate: a three-center-based study of 38 patients

scientific article published on 26 September 2007

HLA-DP4 expression and immunity to NY-ESO-1: correlation and characterization of cytotoxic CD4+ CD25- CD8- T cell clones.

scientific article

Human CD4+ T lymphocytes recognize a vascular endothelial growth factor receptor-2-derived epitope in association with HLA-DR.

scientific article published in July 2008

Humoral and cellular immune responses against the breast cancer antigen NY-BR-1: definition of two HLA-A2 restricted peptide epitopes

scientific article published on 12 December 2005

Identification of Immunohistochemical Reagents for In Situ Protein Expression Analysis of Coronavirus-associated Changes in Human Tissues

scientific article published on 20 October 2020

Identification of a naturally processed NY-ESO-1 peptide recognized by CD8+ T cells in the context of HLA-B51.

scientific article published on 19 September 2002

Identification of cancer/testis genes by database mining and mRNA expression analysis

scientific article

Identification of neoepitopes recognized by tumor-infiltrating lymphocytes (TILs) from patients with glioma.

scientific article

Identification of new NY-ESO-1 epitopes recognized by CD4+ T cells and presented by HLA-DQ B1 03011.

scientific article published on February 2006

Identification of tumor-restricted antigens NY-BR-1, SCP-1, and a new cancer/testis-like antigen NW-BR-3 by serological screening of a testicular library with breast cancer serum.

scientific article published on 28 June 2002

Imatinib mesylate for targeting the platelet-derived growth factor beta receptor in combination with fluorouracil and leucovorin in patients with refractory pancreatic, bile duct, colorectal, or gastric cancer--a dose-escalation Phase I trial

scientific article published on 01 May 2007

Impact of Antigen Presentation on TCR Modulation and Cytokine Release: Implications for Detection and Sorting of Antigen-Specific CD8+ T Cells Using HLA-A2 Wild-Type or HLA-A2 Mutant Tetrameric Complexes

scientific article published on 01 March 2002

Improved detection of melanoma antigen‐specific T cells expressing low or high levels of CD8 by HLA‐A2 tetramers presenting a Melan‐A/Mart‐1 peptide analogue ⬇️

scientific article published on January 1, 2002

In vivo antigen delivery by a Salmonella typhimurium type III secretion system for therapeutic cancer vaccines.

scientific article

Induction of regulatory T cell-resistant helper CD4+ T cells by bacterial vector.

scientific article published on 6 November 2007

Intratumoral T-cell infiltrates and MHC class I expression in patients with stage IV melanoma

scientific article published on 01 May 2005

LBA-008Docetaxel, oxaliplatin, and fluorouracil/leucovorin (FLOT) versus epirubicin, cisplatin, and fluorouracil or capecitabine (ECF/ECX) as perioperative treatment of resectable gastric or gastro-esophageal junction adenocarcinoma: The multicenter,

LUD 00-009: phase 1 study of intensive course immunization with NY-ESO-1 peptides in HLA-A2 positive patients with NY-ESO-1-expressing cancer.

scientific article

Long-term complete remission following radiosurgery and immunotherapy in a melanoma patient with brain metastasis: immunologic correlates

scientific article published on 5 February 2014

Mitomycin C, 5-fluorouracil, leucovorin, and oxaliplatin as a salvage therapy for patients with cisplatin-resistant advanced gastric cancer: a phase I dose escalation trial

scientific article

Modified tumour antigen-encoding mRNA facilitates the analysis of naturally occurring and vaccine-induced CD4 and CD8 T cells in cancer patients

scientific article

Monitoring CD4+ T cell responses against viral and tumor antigens using T cells as novel target APC.

scientific article published in July 2003

NY-ESO-1 protein glycosylated by yeast induces enhanced immune responses

scientific article published on November 2010

NY-ESO-1- and survivin-specific T-cell responses in the peripheral blood from patients with glioma

scientific article

NY-ESO-1-specific immunological pressure and escape in a patient with metastatic melanoma

scientific article published on 15 July 2013

NY-ESO-1: review of an immunogenic tumor antigen

scientific article

Neoepitope targets of tumour-infiltrating lymphocytes from patients with pancreatic cancer

scientific article published on 31 October 2018

Pathological complete remission in patients with oesophagogastric cancer receiving preoperative 5‐fluorouracil, oxaliplatin and docetaxel ⬇️

scientific article published on August 5, 2011

Peptide-specific CD8+ T-cell evolution in vivo: response to peptide vaccination with Melan-A/MART-1.

scientific article

Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4)

scientific article published on 11 April 2019

Phase I clinical trial of mixed bacterial vaccine (Coley's toxins) in patients with NY-ESO-1 expressing cancers: immunological effects and clinical activity

scientific article published on 30 July 2012

Phase I study of everolimus and mitomycin C for patients with metastatic esophagogastric adenocarcinoma ⬇️

scientific article published on 02 April 2013

Phase II study of bortezomib, cyclophosphamide and dexamethasone as induction therapy in multiple myeloma: DSMM XI trial

scientific article published on 29 September 2017

Prognostic Impact of Phosphorylated Mitogen-Activated Protein Kinase Expression in Patients with Metastatic Gastric Cancer ⬇️

scientific article published on June 14, 2011

Prostate cancer progression correlates with increased humoral immune response to a human endogenous retrovirus GAG protein

scientific article published on 30 September 2013

Quantifying and imaging NY-ESO-1/LAGE-1-derived epitopes on tumor cells using high affinity T cell receptors

scientific article published on June 2006

Recombinant antigen expression on yeast surface (RAYS) for the detection of serological immune responses in cancer patients

article

Recombinant vaccinia/fowlpox NY-ESO-1 vaccines induce both humoral and cellular NY-ESO-1-specific immune responses in cancer patients.

scholarly article

Survey of naturally occurring CD4+ T cell responses against NY-ESO-1 in cancer patients: correlation with antibody responses

scientific article

Th1/Th2 CD4+ T cell responses against NY-ESO-1 in HLA-DPB1*0401/0402 patients with epithelial ovarian cancer

scientific article published on 3 November 2004

The differentiation antigen NY-BR-1 is a potential target for antibody-based therapies in breast cancer

scientific article published in June 2007

The discovery of cancer/testis antigens by autologous typing with T cell clones and the evolution of cancer vaccines ⬇️

scientific article published on January 1, 2012

The prognostic impact of epidermal growth factor receptor in patients with metastatic gastric cancer ⬇️

scientific article published on November 15, 2012

Therapeutic administration of a synthetic CpG oligodeoxynucleotide triggers formation of anti-CpG antibodies

scientific article

Trastuzumab plus chemotherapy in gastric cancer overexpressing HER-2 and EGFR: a case report.

scientific article

Tumor antigen-specific T-cells are Present in the CD8alphaalpha+ T-cell effector-memory pool

scientific article published in November 2008

Tumor-reactive CD8+ T-cell clones in patients after NY-ESO-1 peptide vaccination

scientific article

Tumor-reactive CD8+ T-cell responses after vaccination with NY-ESO-1 peptide, CpG 7909 and Montanide ISA-51: association with survival

scientific article

Two phase I studies of low dose recombinant human IL-12 with Melan-A and influenza peptides in subjects with advanced malignant melanoma

scientific article published on 16 July 2003

Urine antibody against human cancer antigen NY-ESO-1

scientific article published on 06 August 2002

Whole-body hyperthermia (WBH) in combination with carboplatin in patients with recurrent ovarian cancer - a phase II study

scientific article

[Long-term remission of malignant melanoma stage IV after antigen-specific immunotherapy]

scientific article published on 01 April 2010

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