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List of works by Brian A Van Tine

<i>nab</i>-Sirolimus for Patients With Malignant Perivascular Epithelioid Cell Tumors

scientific article published in 2021

A Pharmacologic Inhibitor of the Protease Taspase1 Effectively Inhibits Breast and Brain Tumor Growth ⬇️

scientific article published on December 13, 2011

A Phase Ib/II Study of Gemcitabine and Docetaxel in Combination With Pazopanib for the Neoadjuvant Treatment of Soft Tissue Sarcomas

scientific article

A metabolic synthetic lethal strategy with arginine deprivation and chloroquine leads to cell death in ASS1-deficient sarcomas.

scientific article published on 13 October 2016

A phase II clinical study of 13-deoxy, 5-iminodoxorubicin (GPX-150) with metastatic and unresectable soft tissue sarcoma

scientific article published on 23 April 2019

A randomized, open-label, phase 2, multicenter trial of gemcitabine with pazopanib or gemcitabine with docetaxel in patients with advanced soft-tissue sarcoma

scientific article published on 24 November 2020

Alliance A091103 a phase II study of the angiopoietin 1 and 2 peptibody trebananib for the treatment of angiosarcoma

scientific article

Anti-Trop2 blockade enhances the therapeutic efficacy of ErbB3 inhibition in head and neck squamous cell carcinoma.

scientific article published on 5 January 2018

Arginine Starvation and Docetaxel Induce c-Myc-Driven hENT1 Surface Expression to Overcome Gemcitabine Resistance in ASS1-Negative Tumors

scientific article published on 21 May 2019

BRAFV600E mutation in sporadic and neurofibromatosis type 1-related malignant peripheral nerve sheath tumors.

scientific article published on 22 December 2013

Breast tumors educate the proteome of stromal tissue in an individualized but coordinated manner.

scientific article

Circulating tumor cells and biomarker modulation with olaratumab monotherapy followed by olaratumab plus doxorubicin: phase 1b study in soft tissue sarcoma patients

scientific article published on 11 November 2020

Cixutumumab and temsirolimus for patients with bone and soft-tissue sarcoma: a multicentre, open-label, phase 2 trial

scientific article

Clinical outcomes of patients with advanced synovial sarcoma or myxoid/round cell liposarcoma treated at major cancer centers in the United States

scientific article published on 06 May 2020

Clonal selection for transcriptionally active viral oncogenes during progression to cancer.

scientific article

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Conjugation to the sigma-2 ligand SV119 overcomes uptake blockade and converts dm-Erastin into a potent pancreatic cancer therapeutic

scientific article published on 22 May 2016

Correlative Analyses of the SARC028 Trial Reveal an Association Between Sarcoma-Associated Immune Infiltrate and Response to Pembrolizumab

scientific article published on 03 January 2020

Development of 89Zr-Ontuxizumab for in vivo TEM-1/endosialin PET applications

scientific article published on 21 February 2016

Disrupting the enzyme complex regulating O-GlcNAcylation blocks signaling and development

scientific article

Doxorubicin plus evofosfamide versus doxorubicin alone in locally advanced, unresectable or metastatic soft-tissue sarcoma (TH CR-406/SARC021): an international, multicentre, open-label, randomised phase 3 trial

scientific article

Dynamic localization of the human papillomavirus type 11 origin binding protein E2 through mitosis while in association with the spindle apparatus

scientific article published on May 2006

ER and PI3K Independently Modulate Endocrine Resistance in ER-Positive Breast Cancer ⬇️

scientific article published on September 1, 2011

Efficacy and Safety of Trabectedin or Dacarbazine for Metastatic Liposarcoma or Leiomyosarcoma After Failure of Conventional Chemotherapy: Results of a Phase III Randomized Multicenter Clinical Trial.

scientific article published on 14 September 2015

Facts and hopes in immunotherapy of soft tissue sarcomas

scientific article published on 29 June 2020

Gastrointestinal stromal tumors (GISTs): point mutations matter in management, a review

scientific article

Gastrointestinal stromal tumors, version 2.2014.

scientific article published on June 2014

Hepatic epithelioid hemangioendothelioma associated with acute disseminated encephalomyelitis by a possible paraneoplastic process

scientific article published on 25 November 2020

Human breast fibroblasts inhibit growth of the MCF10AT xenograft model of proliferative breast disease

scientific article published on March 2007

Human papillomavirus (HPV) origin-binding protein associates with mitotic spindles to enable viral DNA partitioning

scholarly article

Identification of exogenous forms of human-tropic porcine endogenous retrovirus in miniature Swine

scientific article published on March 2004

Intensity modulated radiation therapy and surgery for Management of Retroperitoneal Sarcomas: a single-institution experience.

scientific article published on 8 December 2017

Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC.

scientific article

Melorheostosis: Exome sequencing of an associated dermatosis implicates postzygotic mosaicism of mutated KRAS.

scientific article published on 20 April 2017

Multi-platform profiling of over 2000 sarcomas: identification of biomarkers and novel therapeutic targets

scientific article published on May 2015

Neoadjuvant Ifosfamide and Epirubicin in the Treatment of Malignant Peripheral Nerve Sheath Tumors.

scientific article

Nivolumab with or without ipilimumab treatment for metastatic sarcoma (Alliance A091401): two open-label, non-comparative, randomised, phase 2 trials

scientific article published on 19 January 2018

Novel pathways and molecular targets for the treatment of sarcoma

scientific article published on August 2013

Novel treatment targets in sarcoma: more than just the GIST

scientific article

Olaratumab and doxorubicin versus doxorubicin alone for treatment of soft-tissue sarcoma: an open-label phase 1b and randomised phase 2 trial

scientific article

PICASSO III: A Phase III, Placebo-Controlled Study of Doxorubicin With or Without Palifosfamide in Patients With Metastatic Soft Tissue Sarcoma.

scientific article published on 12 September 2016

Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial

scientific article published on 4 October 2017

Pharmacokinetics of doxorubicin following concomitant intravenous administration of olaratumab (IMC-3G3) to patients with advanced soft tissue sarcoma

scientific article published on 10 December 2019

Phase II study of the safety and antitumor activity of the hypoxia-activated prodrug TH-302 in combination with doxorubicin in patients with advanced soft tissue sarcoma

scientific article

Real-world outcomes of patients with locally advanced or metastatic epithelioid sarcoma

scientific article published on 09 December 2020

Risk-stratified patients with resectable soft tissue sarcoma benefit from epirubicin-based adjuvant chemotherapy

scientific article

Simultaneous in situ detection of RNA, DNA, and protein using tyramide-coupled immunofluorescence

scientific article published in January 2005

Soft tissue sarcoma, version 2.2012: featured updates to the NCCN guidelines

scientific article

Soft tissue sarcoma, version 2.2014.

scientific article

Systemic Interferon-γ Increases MHC Class I Expression and T-cell Infiltration in Cold Tumors: Results of a Phase 0 Clinical Trial

scientific article published on 06 June 2019

Systems level profiling of arginine starvation reveals MYC and ERK adaptive metabolic reprogramming

scientific article published on 20 August 2020

Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis

scientific article

Taspase1 functions as a non-oncogene addiction protease that coordinates cancer cell proliferation and apoptosis

scientific article

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The Metastatic Spine Disease Multidisciplinary Working Group Algorithms.

scientific article published on 9 September 2015

Whole-genome analysis informs breast cancer response to aromatase inhibition

scientific article

mRNA splicing regulates human papillomavirus type 11 E1 protein production and DNA replication

scientific article

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