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List of works by Michael Laffan

A Mendelian randomization of γ' and total fibrinogen levels on venous thromboembolism and ischemic stroke

scientific article published on 28 July 2020

A comparison between the platelet activating properties of different contrast media used in radiology and MRI ⬇️

scientific article published on 01 August 1997

Abdominal pain in a patient with haemophilia and metallic valve replacement

scientific article published on July 30, 2012

Addendum to British Society for Haematology Guidelines on Investigation and Management of Antiphospholipid syndrome, 2012 (Br. J. Haematol. 2012; 157: 47-58): use of direct acting oral anticoagulants

scientific article published on 13 January 2020

Analysis and results of the recombinant factor VIIa extended-use registry ⬇️

scientific article published on June 1, 2003

Analysis of the F8 gene in individuals with high plasma factor VIII: C levels and associated venous thrombosis

scientific article published on 01 October 1998

Can you grow out of von Willebrand disease?

scientific article published in November 2017

Characterisation of von Willebrand factor A1 domain mutants I1416N and I1416T: correlation of clinical phenotype with flow‐based platelet adhesion ⬇️

scientific article published on 01 July 2012

Clinical phenotype, laboratory features and genotype of 35 patients with heritable dysfibrinogenaemia ⬇️

scientific article published on October 15, 2012

Debate: Should the dose or duration of anticoagulants for the prevention of venous thrombosis be increased in patients with COVID-19 while we are awaiting the results of clinical trials?

scientific article published on 25 November 2020

Defects in TRPM7 channel function deregulate thrombopoiesis through altered cellular Mg(2+) homeostasis and cytoskeletal architecture

scientific article

Diagnostic high-throughput sequencing of 2396 patients with bleeding, thrombotic, and platelet disorders

scientific article published on 01 December 2019

Evaluation of von Willebrand factor concentrates by platelet adhesion to collagen using an in vitro flow assay

scientific article published on 07 December 2018

Expanded repertoire of RASGRP2 variants responsible for platelet dysfunction and severe bleeding

scientific article published on 21 June 2017

Fibrinogen polymorphisms and disease ⬇️

scientific article published on 01 December 2001

Genetically Determined FXI (Factor XI) Levels and Risk of Stroke

article

Genetically Determined Platelet Count and Risk of Cardiovascular Disease

scientific article published on 01 December 2018

Germline mutations in the transcription factor IKZF5 cause thrombocytopenia

scientific article published on 01 December 2019

Guidelines on the laboratory aspects of assays used in haemostasis and thrombosis

scientific article published on 14 June 2020

Inherited platelet disorders: toward DNA-based diagnosis

scientific article

International Society on Thrombosis and Haemostasis core curriculum project: core competencies in clinical thrombosis and hemostasis

scientific article published on 6 October 2015

Intracranial Hemorrhage and Early Mortality in Patients Receiving Extracorporeal Membrane Oxygenation for Severe Respiratory Failure

scientific article published on 22 March 2018

Limitations on point care APTT for monitoring of unfractionated heparin in intensive care patients

scientific article published on 01 August 2019

Making contact with microparticles ⬇️

scientific article published on 01 July 2012

Multiyear Follow-up of AAV5-hFVIII-SQ Gene Therapy for Hemophilia A

scientific article published on 01 January 2020

NICE NG89 recommendations for extended pharmacological thromboprophylaxis - is it justified and is it cost effective: a rebuttal from the British Society for Haematology

scientific article published on 05 June 2019

New oral anticoagulants: should they replace heparins and warfarin?

scientific article published on January 1, 2011

New oral anticoagulants: their role and future

scientific article

O-linked glycosylation of von Willebrand factor modulates the interaction with platelet receptor glycoprotein Ib under static and shear stress conditions ⬇️

scientific article published on April 19, 2012

Partial rescue of naturally occurring active site factor X variants through decreased inhibition by tissue factor pathway inhibitor and antithrombin

scientific article published on 20 September 2019

Pathogenesis and Management of Thrombotic Disease in Myeloproliferative Neoplasms

scientific article published on 05 August 2019

Pharmacokinetics, phenotype and product choice in haemophilia B: how to strike a balance?

scientific article published in November 2014

Phenotype description and response to thrombopoietin receptor agonist in -related disorder

scientific article published on 01 September 2018

Platelet dysfunction associated with ponatinib, a new pan BCR-ABL inhibitor with efficacy for chronic myeloid leukemia resistant to multiple tyrosine kinase inhibitor therapy ⬇️

scientific article published on April 24, 2012

Pregnancy in type 2B VWD: a case series ⬇️

scientific article published on November 14, 2011

Purified factor VIII ⬇️

scientific article published on August 19, 1995

Randomised trials of human albumin for adults with sepsis: systematic review and meta-analysis with trial sequential analysis of all-cause mortality

scientific article

Recommendations for the clinical interpretation of genetic variants and presentation of results to patients with inherited bleeding disorders. A UK Haemophilia Centre Doctors' Organisation Good Practice Paper

scientific article published on 01 January 2019

Safety and pharmacokinetics of anti-TFPI antibody (concizumab) in healthy volunteers and patients with hemophilia: a randomized first human dose trial

scientific article published on 6 April 2015

Site-specific analysis of von Willebrand factor O-glycosylation

scientific article published on 19 January 2016

Specific treatment for cancer-associated thrombosis

scientific article published on 15 October 2015

The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension

scientific article published on 28 March 2019

The diagnosis and management of von Willebrand disease: a United Kingdom Haemophilia Centre Doctors Organization guideline approved by the British Committee for Standards in Haematology

scientific article

The effects of pathogenic and likely pathogenic variants for inherited hemostasis disorders in 140 214 UK Biobank participants

The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing

scientific article published on 11 April 2019

The heparin-von Willebrand factor interaction and conventional tests of haemostasis - the challenges in predicting bleeding in cardiopulmonary bypass

scientific article published on 05 December 2020

The top 10 research priorities in bleeding disorders: a James Lind Alliance Priority Setting Partnership

scientific article published on 23 April 2019

The use of viscoelastic haemostatic assays in the management of major bleeding: A British Society for Haematology Guideline

scientific article published on 02 August 2018

Thrombolysis restores perfusion in COVID 19 hypoxia

scientific article published on 31 July 2020

Thrombophilia in non-thrombotic chronic venous disease of the lower limb - a systematic review

scientific article published on 01 December 2018

Thrombophilia: an expanding group of genetic defects that predispose to thrombosis ⬇️

scientific article published on July 1, 1997

Use of Antithrombin Concentrate for Acquired Antithrombin Deficiency in Acutely Unwell Children Receiving Unfractionated Heparin

scientific article published on 21 October 2019

Utility of fibrinogen in the coagulation screen.

scientific article

Von Willebrand factor and angiogenesis: basic and applied issues

scientific article

announcement: Non‐malignant haematology research in the UK: looking forward to new opportunities ⬇️

scientific article published on September 1, 2010

von Willebrand disease: Diagnosis and treatment, treatment of women, and genomic approach to diagnosis

scientific article published on 23 June 2020

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