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List of works by Christophe Erneux

5-Stabilized phosphatidylinositol 3,4,5-trisphosphate analogues bind Grp1 PH, inhibit phosphoinositide phosphatases, and block neutrophil migration

scientific article

A Synthetic Polyphosphoinositide Headgroup Surrogate in Complex with SHIP2 Provides a Rationale for Drug Discovery ⬇️

scientific article published on February 27, 2012

A diverse family of inositol 5-phosphatases playing a role in growth and development in Dictyostelium discoideum

scientific article published on 2 December 2002

A small molecule inhibitor for phosphatase and tensin homologue deleted on chromosome 10 (PTEN).

scientific article published on December 2006

Abnormal elevated PTEN expression in the mouse antrum of a model of GIST KitK641E/K641E ⬇️

scientific article published on July 3, 2011

Astrocytic IP3/Ca2+ Signaling Modulates Theta Rhythm and REM Sleep

scientific article published on 23 January 2017

Benzene polyphosphates as tools for cell signalling: inhibition of inositol 1,4,5-trisphosphate 5-phosphatase and interaction with the PH domain of protein kinase Balpha.

scientific article published on July 2008

Biphenyl 2,3',4,5',6-pentakisphosphate, a novel inositol polyphosphate surrogate, modulates Ca2+ responses in rat hepatocytes

scientific article published on 30 January 2007

ENDOGLIN/CD105 is expressed in KIT positive cells in the gut and in gastrointestinal stromal tumours ⬇️

scientific article published on February 1, 2012

Evidence of SHIP2 Ser132 phosphorylation, its nuclear localization and stability

scientific article

Fibroblasts derived from patients with opsismodysplasia display SHIP2-specific cell migration and adhesion defects

scientific article published on 4 September 2017

How does SHIP1/2 balance PtdIns(3,4)P2 and does it signal independently of its phosphatase activity? ⬇️

scientific article published on May 7, 2013

Hydrogen peroxide and epidermal growth factor activate phosphatidylinositol 3-kinase and increase sodium transport in A6 cell monolayers.

scientific article published on 25 January 2005

Hyperosmotic stress stimulates inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate formation independently of bis-diphosphoinositol tetrakisphosphate modulation

scientific article published on October 2005

Hyperplasia of interstitial cells of cajal in sprouty homolog 4 deficient mice

scientific article

IPMK and β-catenin mediate PLC-β1-dependent signaling in myogenic differentiation

scientific article published on 23 August 2016

Identification and subcellular distribution of endogenous Ins(1,4,5)P(3) 3-kinase B in mouse tissues

scientific journal article

Inhibition of SHIP2 activity inhibits cell migration and could prevent metastasis in breast cancer cells

scientific article published on 16 August 2018

Inhibition of insulin-stimulated hydrogen peroxide production prevents stimulation of sodium transport in A6 cell monolayers

scientific article published on 18 March 2009

Inositol 1,3,4,5-tetrakisphosphate controls proapoptotic Bim gene expression and survival in B cells

scientific article

Inositol 1,3,4,5-tetrakisphosphate is essential for T lymphocyte development ⬇️

scientific article published on September 28, 2003

Inositol 1,3,4,5-tetrakisphosphate negatively regulates phosphatidylinositol-3,4,5- trisphosphate signaling in neutrophils

scientific article published on 6 September 2007

Inositol trisphosphate 3-kinase B (InsP3KB) as a physiological modulator of myelopoiesis

scientific journal article

Inositol trisphosphate 3-kinase B is increased in human Alzheimer brain and exacerbates mouse Alzheimer pathology

scientific article published on 8 January 2014

Inositol(1,4,5)P3 3-kinase isoenzymes: Catalytic properties and importance of targeting to F-actin to understand function

scientific article published on 26 September 2015

Kit K641E oncogene up-regulates Sprouty homolog 4 and trophoblast glycoprotein in interstitial cells of Cajal in a murine model of gastrointestinal stromal tumours

scientific article published on 19 May 2009

Multivalent benzene polyphosphate derivatives are non-Ca2+-mobilizing Ins(1,4,5)P3 receptor antagonists

scientific article published on December 2012

Neurotensin Receptor 1 Is Expressed in Gastrointestinal Stromal Tumors but Not in Interstitial Cells of Cajal ⬇️

scientific article published on February 18, 2011

Phosphatidylinositol 3,4,5-trisphosphate modulation in SHIP2-deficient mouse embryonic fibroblasts

scientific article published on May 2005

Phosphatidylinositol 3,4,5-trisphosphate: an early mediator of insulin-stimulated sodium transport in A6 cells

scientific article published on 20 April 2004

Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle

scientific article published on October 2013

Phosphodiesterase 3A: a new player in development of interstitial cells of Cajal and a prospective target in gastrointestinal stromal tumors (GIST).

scientific article

Phosphoinositide phosphatases in a network of signalling reactions

scientific article published on 29 June 2007

Reactive blue 2 inhibition of cyclic AMP-dependent differentiation of rat C6 glioma cells by purinergic receptor-independent inactivation of phosphatidylinositol 3-kinase

scientific article published in April 2004

SH2-containing inositol 5-phosphatases 1 and 2 in blood platelets: their interactions and roles in the control of phosphatidylinositol 3,4,5-trisphosphate levels

scientific article

SHIP1/2 interaction with tyrosine phosphorylated peptides mimicking an immunoreceptor signalling motif

scientific article published on 31 July 2006

SHIP2 (SH2 domain-containing inositol phosphatase 2) SH2 domain negatively controls SHIP2 monoubiquitination in response to epidermal growth factor

scientific article published on 30 October 2009

SHIP2 controls PtdIns(3,4,5)P(3) levels and PKB activity in response to oxidative stress

scientific article published on 30 June 2007

SHIP2 controls plasma membrane PI(4,5)P2 thereby participating in the control of cell migration in 1321 N1 glioblastoma cells

scientific article published on 29 January 2016

SHIP2 interaction with the cytoskeletal protein Vinexin

scientific article

SHIP2 multiple functions: A balance between a negative control of PtdIns(3,4,5)P3 level, a positive control of PtdIns(3,4)P2 production, and intrinsic docking properties ⬇️

scientific article published on September 1, 2011

SHIP2 overexpression strongly reduces the proliferation rate of K562 erythroleukemia cell line

scientific article (publication date: 9 August 2002)

SHIP2 regulates epithelial cell polarity through its lipid product, which binds to Dlg1, a pathway subverted by hepatitis C virus core protein ⬇️

scientific article published on May 22, 2013

SHIP2 signaling in normal and pathological situations: Its impact on cell proliferation

scientific article published on 15 September 2013

SHIP2 signalling at the plasma membrane, in the nucleus and at focal contacts ⬇️

scientific article published on September 13, 2012

SHIP2: Structure, Function and Inhibition

scientific article published on 30 November 2016

The Host Phosphoinositide 5-Phosphatase SHIP2 Regulates Dissemination of Vaccinia Virus ⬇️

scientific article published on May 4, 2011

The SHIP2 interactor Myo1c is required for cell migration in 1321 N1 glioblastoma cells

scientific article published on 28 May 2016

The Shigella type III effector IpgD recodes Ca2+ signals during invasion of epithelial cells.

scientific article published on 12 July 2017

The absence of expression of the three isoenzymes of the inositol 1,4,5-trisphosphate 3-kinase does not prevent the formation of inositol pentakisphosphate and hexakisphosphate in mouse embryonic fibroblasts

scientific article published on 3 February 2007

The association between the SH2-containing inositol polyphosphate 5-Phosphatase 2 (SHIP2) and the adaptor protein APS has an impact on biochemical properties of both partners

scientific article

The c-Cbl-associated protein and c-Cbl are two new partners of the SH2-containing inositol polyphosphate 5-phosphatase SHIP2

scientific article

The impact of phosphoinositide 5-phosphatases on phosphoinositides in cell function and human disease

scientific article published on 07 September 2018

The influence of anionic lipids on SHIP2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase activity

scientific article published on 23 May 2006

The inositol Inpp5k 5-phosphatase affects osmoregulation through the vasopressin-aquaporin 2 pathway in the collecting system

scientific journal article

The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases

scientific article published on 18 September 2018

The role of calmodulin for inositol 1,4,5-trisphosphate receptor function

scientific article

The termination of PI3K signalling by SHIP1 and SHIP2 inositol 5-phosphatases

scientific article

The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cells ⬇️

scientific article published on August 15, 2003

Thyrotropin stimulates the generation of inositol 1,4,5-trisphosphate in human thyroid cells

scientific article published on 29 December 2005

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