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List of works by Tomoyoshi Nozaki

"Inject-mix-react-separate-and-quantitate" (IMReSQ) method for screening enzyme inhibitors

scientific article

A case of quadruple malaria infection imported from Mozambique to Japan

scientific article

A key role for old yellow enzyme in the metabolism of drugs by Trypanosoma cruzi

scientific article

A novel class of cysteine protease receptors that mediate lysosomal transport ⬇️

scientific article published on May 14, 2012

A retromerlike complex is a novel Rab7 effector that is involved in the transport of the virulence factor cysteine protease in the enteric protozoan parasite Entamoeba histolytica

scientific article

AGC family kinase 1 participates in trogocytosis but not in phagocytosis in Entamoeba histolytica

scientific article

AIG1 affects in vitro and in vivo virulence in clinical isolates of Entamoeba histolytica.

scientific article published on 19 March 2018

Amebiasis in HIV-1-Infected Japanese Men: Clinical Features and Response to Therapy ⬇️

scientific article published on September 13, 2011

An Entamoeba cysteine peptidase specifically expressed during encystation

scientific article

An Entamoeba-Specific Mitosomal Membrane Protein with Potential Association to the Golgi Apparatus.

scientific article published on 13 May 2019

An atypical EhGEF regulates phagocytosis in Entamoeba histolytica through EhRho1

scientific article published on 22 November 2021

An autopsy case of Balamuthia mandrillaris amoebic encephalitis, a rare emerging infectious disease, with a brief review of the cases reported in Japan

scientific article

An intestinal parasitic protist, Entamoeba histolytica, possesses a non-redundant nitrogen fixation-like system for iron-sulfur cluster assembly under anaerobic conditions

scientific article published on 2 February 2004

Analysis of autophagy in the enteric protozoan parasite Entamoeba

scientific article published on 01 January 2008

Association between Giardia duodenalis and coinfection with other diarrhea-causing pathogens in India.

scientific article

Attention-getting zoonoses: Cryptosporidiosis

scientific article published in November 2007

Autophagy during proliferation and encystation in the protozoan parasite Entamoeba invadens

scientific article published on 8 October 2007

Bacterial-type oxygen detoxification and iron-sulfur cluster assembly in amoebal relict mitochondria

scientific article published on 03 November 2009

Behavior of DNA-lacking mitochondria in Entamoeba histolytica revealed by organelle transplant

scientific article

Biochemical and functional characterization of novel NADH kinase in the enteric protozoan parasite Entamoeba histolytica

scientific article published on 13 October 2012

Biochemical and functional characterization of phosphoserine aminotransferase from Entamoeba histolytica, which possesses both phosphorylated and non-phosphorylated serine metabolic pathways

scientific article

Biochemical studies of membrane bound Plasmodium falciparum mitochondrial L-malate:quinone oxidoreductase, a potential drug target

scientific article published on 18 December 2017

Biochemical, Metabolomic, and Genetic Analyses of Dephospho Coenzyme A Kinase Involved in Coenzyme A Biosynthesis in the Human Enteric Parasite Entamoeba histolytica

scientific article published on 30 November 2018

Biophysical characterization of Entamoeba histolytica phosphoserine aminotransferase (EhPSAT): role of cofactor and domains in stability and subunit assembly ⬇️

scientific article published on December 16, 2010

Case Report: Acute Amebic Colitis Triggered by Colonoscopy: Exacerbation of Asymptomatic Chronic Infection with Entamoeba histolytica Accompanied by Dysbiosis

scientific article published on 01 December 2019

Characterization and validation of Entamoeba histolytica pantothenate kinase as a novel anti-amebic drug target.

scientific article published in March 2018

Characterization of protein geranylgeranyltransferase I from the enteric protist Entamoeba histolytica

scientific article published on 19 October 2005

Characterization of two isotypes of l-threonine dehydratase from Entamoeba histolytica

scientific article published on 18 November 2009

Complete sequence and characterization of the mitochondrial genome of Diphyllobothrium stemmacephalum, the type species of genus Diphyllobothrium (Cestoda: Diphyllobothriidae), using next generation sequencing

scientific article published on 21 June 2017

Conservation and function of Rab small GTPases in Entamoeba: annotation of E. invadens Rab and its use for the understanding of Entamoeba biology

scientific article published on 29 April 2010

Crystallization and preliminary X-ray analysis of L-methionine gamma-lyase 1 from Entamoeba histolytica

scientific article

Current therapeutics, their problems, and sulfur-containing-amino-acid metabolism as a novel target against infections by "amitochondriate" protozoan parasites

scientific article

Cysteine protease-binding protein family 6 mediates the trafficking of amylases to phagosomes in the enteric protozoan Entamoeba histolytica

scientific article

Differences in morphology of phagosomes and kinetics of acidification and degradation in phagosomes between the pathogenic Entamoeba histolytica and the non-pathogenic Entamoeba dispar

scientific article published in October 2005

Differential gene expression in Giardia lamblia under oxidative stress: significance in eukaryotic evolution.

scientific article published on 7 December 2013

Discovery of Antiamebic Compounds That Inhibit Cysteine Synthase From the Enteric Parasitic Protist by Screening of Microbial Secondary Metabolites

scholarly article by Mihoko Mori et al published 2018 in Frontiers in cellular and infection microbiology

Dramatic Increase in Glycerol Biosynthesis upon Oxidative Stress in the Anaerobic Protozoan Parasite Entamoeba histolytica ⬇️

scientific article published on September 27, 2012

Dynamism of PI4-Phosphate during Interactions with Human Erythrocytes in Entamoeba histolytica

scientific article published on 15 July 2020

Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo

scientific article published on January 2004

Entamoeba histolytica Phosphoserine aminotransferase (EhPSAT): insights into the structure-function relationship

scientific article

Entamoeba histolytica: differences in phagosome acidification and degradation between attenuated and virulent strains

scientific article published on 20 March 2006

Entamoeba histolytica: molecular cloning and characterization of a novel neutral sphingomyelinase

scientific article published on 6 February 2010

Epidemiology of Domestically Acquired Amebiasis in Japan, 2000-2013.

scientific article published on 14 March 2016

Erratum: AIG1 affects in vitro and in vivo virulence in clinical isolates of Entamoeba histolytica.

scientific article published on 31 May 2018

Expression profiles of peroxiredoxin proteins of the rodent malaria parasite Plasmodium yoelii

scientific article published in November 2003

Genetic diversity of Entamoeba: Novel ribosomal lineages from cockroaches

scientific article published on 21 September 2017

Genetic, metabolomic and transcriptomic analyses of the de novo L-cysteine biosynthetic pathway in the enteric protozoan parasite Entamoeba histolytica

scientific article published on 15 November 2017

Global analysis of gene expression in response to L-Cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica ⬇️

scientific article published on May 31, 2011

Glu-108 is essential for subunit assembly and dimer stability of d-phosphoglycerate dehydrogenase from Entamoeba histolytica ⬇️

scientific article published on October 23, 2011

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Hetero-oligomer of dynamin-related proteins participates in the fission of highly divergent mitochondria from Entamoeba histolytica

scientific article published on 18 October 2017

Highly divergent mitochondrion-related organelles in anaerobic parasitic protozoa

scientific article

Identification and Characterization of the Entamoeba Histolytica Rab8a Binding Protein: A Cdc50 Homolog

scientific article published in 2018

Identification and characterization of two isoenzymes of methionine gamma-lyase from Entamoeba histolytica: a key enzyme of sulfur-amino acid degradation in an anaerobic parasitic protist that lacks forward and reverse trans-sulfuration pathways

scientific article

Identification and gene expression analysis of a large family of transmembrane kinases related to the Gal/GalNAc lectin in Entamoeba histolytica

scientific article

Identification of Plasmodium falciparum Mitochondrial Malate: Quinone Oxidoreductase Inhibitors from the Pathogen Box

scientific article published on 21 June 2019

Identification of an avirulent Entamoeba histolytica strain with unique tRNA-linked short tandem repeat markers.

scientific article published on 4 November 2009

Identification of natural inhibitors of Entamoeba histolytica cysteine synthase from microbial secondary metabolites

scientific article

Ikoamide, an Antimalarial Lipopeptide from an Okeania sp. Marine Cyanobacterium

scientific article published on 10 February 2020

Impact of intestinal colonization and invasion on the Entamoeba histolytica transcriptome

scientific article

Import of Entamoeba histolytica Mitosomal ATP Sulfurylase Relies on Internal Targeting Sequences

scientific article published on 12 August 2020

Insights into the GTP/GDP cycle of RabX3, a novel GTPase from Entamoeba histolytica with tandem G-domains

scientific article

Interaction between Nbp35 and Cfd1 proteins of cytosolic Fe-S cluster assembly reveals a stable complex formation in Entamoeba histolytica

scientific article

Iron-sulphur clusters, their biosynthesis, and biological functions in protozoan parasites

scientific article published on January 2013

Isoform-dependent feedback regulation of serine O-acetyltransferase isoenzymes involved in L-cysteine biosynthesis of Entamoeba histolytica

scientific article published on 23 September 2008

Isolation and Total Synthesis of Mabuniamide, a Lipopeptide from an Okeania sp. Marine Cyanobacterium

scientific article published on 24 September 2019

Kinetic characterization of methionine gamma-lyases from the enteric protozoan parasite Entamoeba histolytica against physiological substrates and trifluoromethionine, a promising lead compound against amoebiasis

scientific article

Kinetics and strain variation of phagosome proteins of Entamoeba histolytica by proteomic analysis

scientific article published on 19 October 2005

Ligand heterogeneity of the cysteine protease binding protein family in the parasitic protist Entamoeba histolytica

scientific article published on 5 June 2014

Localization and targeting of an unusual pyridine nucleotide transhydrogenase in Entamoeba histolytica

scientific article

Marked Amplification and Diversification of Products of ras Genes from Rat Brain, Rab GTPases, in the Ciliates Tetrahymena thermophila and Paramecium tetraurelia ⬇️

scientific article published on September 1, 2010

Mass spectrometric analysis of L-cysteine metabolism: physiological role and fate of L-cysteine in the enteric protozoan parasite Entamoeba histolytica

scientific article

Membrane trafficking as a virulence mechanism of the enteric protozoan parasite Entamoeba histolytica

scientific article

Metabolic profiling of the protozoan parasite Entamoeba invadens revealed activation of unpredicted pathway during encystation

scientific article

Metabolome Analysis Revealed Increase in S-Methylcysteine and Phosphatidylisopropanolamine Synthesis upon l-Cysteine Deprivation in the Anaerobic Protozoan Parasite Entamoeba histolytica ⬇️

scientific article published on October 5, 2010

Metabolomic analysis of Entamoeba: applications and implications

scientific article

Methionine gamma-lyase: the unique reaction mechanism, physiological roles, and therapeutic applications against infectious diseases and cancers

scientific article

Mitosomes in Entamoeba histolytica contain a sulfate activation pathway

scientific article

Molecular Cloning and Characterization of a Protein Farnesyltransferase from the Enteric Protozoan Parasite Entamoeba histolytica ⬇️

scientific article published on October 28, 2003

Molecular and biochemical characterization of D-phosphoglycerate dehydrogenase from Entamoeba histolytica. A unique enteric protozoan parasite that possesses both phosphorylated and nonphosphorylated serine metabolic pathways

scientific article

Molecular and structural characterization of NADPH-dependent d-glycerate dehydrogenase from the enteric parasitic protist Entamoeba histolytica

scientific article

Molecular characterization and assessment of zoonotic transmission of Cryptosporidium from dairy cattle in West Bengal, India

scientific article published on 11 March 2010

Molecular evidence for zoonotic transmission of Giardia duodenalis among dairy farm workers in West Bengal, India

scientific article published on 26 January 2011

Multilocus sequence typing system (MLST) reveals a significant association of Entamoeba histolytica genetic patterns with disease outcome

scientific article published on 7 December 2013

Multisite Performance Evaluation of an Enzyme-Linked Immunosorbent Assay for Detection of Giardia, Cryptosporidium, and Entamoeba histolytica Antigens in Human Stool ⬇️

scientific article published on February 29, 2012

Near-chromosome level genome assembly reveals ploidy diversity and plasticity in the intestinal protozoan parasite Entamoeba histolytica

scientific article published on 23 November 2020

New insights into molecular mechanisms of phagocytosis in Entamoeba histolytica by proteomic analysis

scientific article

Non-vesicular Lipid Transport Machinery in

scholarly article by Koushik Das & Tomoyoshi Nozaki published 19 September 2018 in Frontiers in cellular and infection microbiology

Novel TPR-containing subunit of TOM complex functions as cytosolic receptor for Entamoeba mitosomal transport

scientific article published on 24 January 2013

Novel Transmembrane Receptor Involved in Phagosome Transport of Lysozymes and β-Hexosaminidase in the Enteric Protozoan Entamoeba histolytica ⬇️

scientific article published on February 23, 2012

Novel lineage-specific transmembrane β-barrel proteins in the endoplasmic reticulum of Entamoeba histolytica

scientific article published on 20 May 2019

Novel protein–protein interactions between Entamoeba histolytica d-phosphoglycerate dehydrogenase and phosphoserine aminotransferase ⬇️

scientific article published on February 24, 2012

Oxidative stress-induced cell cycle blockage and a protease-independent programmed cell death in microaerophilic Giardia lamblia.

scientific article published on 21 September 2009

Phosphatidylinositol Kinases and Phosphatases in Entamoeba histolytica.

scientific article published on 6 June 2019

Phosphatidylinositol-phosphates mediate cytoskeletal reorganization during phagocytosis via a unique modular protein consisting of RhoGEF/DH and FYVE domains in the parasitic protozoon Entamoeba histolytica

scientific article published on 3 June 2009

Plant hormone cytokinins control cell cycle progression and plastid replication in apicomplexan parasites

scientific article published on 23 March 2017

Prevalence and distribution of Entamoeba species in a rural community in northern South Africa

scientific article published on 20 February 2020

Prostaglandin production from arachidonic acid and evidence for a 9,11-endoperoxide prostaglandin H2 reductase in Leishmania

scientific article (publication date: 19 December 2002)

Prostaglandin production from arachidonic acid and evidence for a 9,11-endoperoxide prostaglandin H2 reductase in Leishmania

scientific article (publication date: February 2003)

Proteomic analysis of Entamoeba histolytica in vivo assembled pre-mRNA splicing complexes

scientific article published on 8 August 2014

Proteomic analysis of phagocytosis in the enteric protozoan parasite Entamoeba histolytica

scientific article

Pyruvate Protects Giardia Trophozoites from Cysteine-Ascorbate Deprived Medium Induced Cytotoxicity.

scientific article

Rab11B small GTPase regulates secretion of cysteine proteases in the enteric protozoan parasite Entamoeba histolytica

scientific article published on 17 April 2007

Rab5-associated vacuoles play a unique role in phagocytosis of the enteric protozoan parasite Entamoeba histolytica

scientific article published on 3 September 2004

Rab7D small GTPase is involved in phago-, trogocytosis and cytoskeletal reorganization in the enteric protozoan Entamoeba histolytica

scientific article published on 25 September 2020

Role of EhRab7A in phagocytosis of type 1 fimbriated E. coli by Entamoeba histolytica

scientific article published on 24 September 2016

Role of conserved active site tryptophan-101 in functional activity and stability of phosphoserine aminotransferase from an enteric human parasite

scientific article published on 29 October 2011

Structural and Biochemical Features of <i>Eimeria tenella</i> Dihydroorotate Dehydrogenase, a Potential Drug Target

scientific article published on 07 December 2020

Sulfur-containing amino acid metabolism in parasitic protozoa

scientific article

Sulfur-containing amino acid metabolism in parasitic protozoa

scientific article published in January 2002

Targeted deletion of the gp72 gene decreases the infectivity of Trypanosoma cruzi for mice and insect vectors

scientific article published in June 2002

The Entamoeba histolytica Dnmt2 homolog (Ehmeth) confers resistance to nitrosative stress

scientific article published on 21 February 2014

The cell surface proteome of Entamoeba histolytica

scientific article published on 17 October 2013

The diversity of Rab GTPases in Entamoeba histolytica

scientific article published on 7 April 2005

Transcriptome analysis of encystation in Entamoeba invadens

scientific article

Trend of Entamoeba histolytica infestation in Kolkata ⬇️

scientific article published on October 6, 2010

Two Rab7 isotypes, EhRab7A and EhRab7B, play distinct roles in biogenesis of lysosomes and phagosomes in the enteric protozoan parasite Entamoeba histolytica

scientific article published on 13 March 2007

Two atypical L-cysteine-regulated NADPH-dependent oxidoreductases involved in redox maintenance, L-cystine and iron reduction, and metronidazole activation in the enteric protozoan Entamoeba histolytica

scientific article

Two cysteine protease inhibitors, EhICP1 and 2, localized in distinct compartments, negatively regulate secretion in Entamoeba histolytica

scientific article published on 12 September 2006

Two isotypes of phosphatidylinositol 3-phosphate-binding sorting nexins play distinct roles in trogocytosis in Entamoeba histolytica

scientific article published on 01 December 2019

Underestimated Amoebic Appendicitis among HIV-1-Infected Individuals in Japan

scientific article

X-Ray snapshots of a pyridoxal enzyme: a catalytic mechanism involving concerted [1,5]-hydrogen sigmatropy in methionine γ-lyase

scientific article

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