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List of works by Alain Beck

Antibody-Drug Conjugates: The Last Decade

scientific article published on 14 September 2020

Characterization of the N-terminal heterogeneities of monoclonal antibodies using in-gel charge derivatization of α-amines and LC-MS/MS.

scientific article

Characterization of therapeutic antibodies and related products.

scientific article published on 14 December 2012

Comprehensive study on the effects of sodium and potassium additives in size exclusion chromatographic separations of protein biopharmaceuticals

scientific article published on 26 September 2016

Coupling non-denaturing chromatography to mass spectrometry for the characterization of monoclonal antibodies and related products

scientific article published on 25 February 2020

Current possibilities of liquid chromatography for the characterization of antibody-drug conjugates

scientific article

Cutting-edge mass spectrometry characterization of originator, biosimilar and biobetter antibodies

scientific article published on February 2015

Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates.

scientific article

Glycosylation of biosimilars: Recent advances in analytical characterization and clinical implications

scientific article published on 22 August 2019

High-resolution separation of monoclonal antibodies mixtures and their charge variants by an alternative and generic CZE method

scientific article published on 04 June 2018

Hydrophobic interaction chromatography for the characterization of monoclonal antibodies and related products

scientific article published on 4 April 2016

Impact of organic modifier and temperature on protein denaturation in hydrophobic interaction chromatography

scientific article published on 26 August 2016

Innovative native MS methodologies for antibody drug conjugate characterization: High resolution native MS and IM-MS for average DAR and DAR distribution assessment.

scientific article published on 21 October 2014

Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry

scientific article published on 19 August 2020

Ion-exchange chromatography for the characterization of biopharmaceuticals

scientific article published on 26 February 2015

Macro- and Micro-Heterogeneity of Natural and Recombinant IgG Antibodies

scientific article published on 19 February 2019

Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine-linked antibody drug conjugate

scientific article

Optimized Sample Preparation and Data Processing of Data-Independent Acquisition Methods for the Robust Quantification of Trace-Level Host Cell Protein Impurities in Antibody Drug Products

scientific article published on 04 October 2020

Potential of hydrophilic interaction chromatography for the analytical characterization of protein biopharmaceuticals

scientific article published on 22 April 2016

Proof of Concept To Achieve Infinite Selectivity for the Chromatographic Separation of Therapeutic Proteins

scientific article published on 25 September 2019

Theory and practice of size exclusion chromatography for the analysis of protein aggregates

scientific article

Time resolved native ion-mobility mass spectrometry to monitor dynamics of IgG4 Fab arm exchange and "bispecific" monoclonal antibody formation

scientific article published on 26 September 2013

Unraveling the mysteries of modern size exclusion chromatography - the way to achieve confident characterization of therapeutic proteins

scientific article published on 18 June 2018

Use of Ultra-short Columns for Therapeutic Protein Separations, Part 2: Designing the Optimal Column Dimension for Reversed-Phase Liquid Chromatography

scientific article published on 11 December 2020

Use of Ultrashort Columns for Therapeutic Protein Separations. Part 1: Theoretical Considerations and Proof of Concept

scientific article published on 17 December 2020