Search filters

List of works by Douglas S Hawkins

18F‐FDG microPET imaging detects early transient response to an IGF1R inhibitor in genetically engineered rhabdomyosarcoma models ⬇️

scientific article published on January 11, 2012

45 Gy is not sufficient radiotherapy dose for Group III orbital embryonal rhabdomyosarcoma after less than complete response to 12 weeks of ARST0331 chemotherapy: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group

scientific article published on 26 May 2017

A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer ⬇️

scientific article published on August 2, 2013

A risk-based treatment strategy for non-rhabdomyosarcoma soft-tissue sarcomas in patients younger than 30 years (ARST0332): a Children's Oncology Group prospective study

scientific article published on 27 November 2019

Addition of Vincristine and Irinotecan to Vincristine, Dactinomycin, and Cyclophosphamide Does Not Improve Outcome for Intermediate-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group

Allergies, atopy, immune-related factors and childhood rhabdomyosarcoma: a report from the Children's Oncology Group.

scientific article published on August 2013

Alveolar rhabdomyosarcoma with regional nodal involvement: Results of a combined analysis from two cooperative groups

scientific article published on 27 November 2020

An unresolved issue in rhabdomyosarcoma treatment: The duration of chemotherapy

scientific article published on 28 January 2020

Asparaginase pharmacokinetics after intensive polyethylene glycol-conjugated L-asparaginase therapy for children with relapsed acute lymphoblastic leukemia

scientific article

Benefit of delayed primary excision in rhabdomyosarcoma: A report from the Children's Oncology Group (COG)

scientific article published on 20 October 2020

Body mass index (BMI) at diagnosis is associated with surgical wound complications in patients with localized osteosarcoma: a report from the Children's Oncology Group

scientific article

Broad Spectrum Activity of the Checkpoint Kinase 1 Inhibitor Prexasertib as a Single Agent or Chemopotentiator Across a Range of Preclinical Pediatric Tumor Models

scientific article published on 18 December 2018

CD49b inhibits osteogenic differentiation and plays an important role in osteosarcoma progression.

scientific article published on 23 September 2017

Clinical Application of Prognostic Gene Expression Signature in Fusion Gene-Negative Rhabdomyosarcoma: A Report from the Children's Oncology Group

scientific article

Clinical and Genetic Risk Prediction of Subsequent CNS Tumors in Survivors of Childhood Cancer: A Report From the COG ALTE03N1 Study.

scientific article published on 4 October 2017

Clinical and mutational spectrum of highly differentiated, paired box 3:forkhead box protein o1 fusion-negative rhabdomyosarcoma: A report from the Children's Oncology Group

scientific article published on 20 February 2018

Clinical features and outcomes of young patients with epithelioid sarcoma: an analysis from the Children's Oncology Group and the European paediatric soft tissue Sarcoma Study Group prospective clinical trials

scientific article published on 05 April 2019

Clinical trial enrollment of adolescents and young adults with sarcoma.

scientific article published on 11 May 2017

Clonality and evolutionary history of rhabdomyosarcoma

scientific article

Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial. ⬇️

scientific article

Comparison of genome-wide binding of MyoD in normal human myogenic cells and rhabdomyosarcomas identifies regional and local suppression of promyogenic transcription factors.

scientific article published on 10 December 2012

Comparison of results of a pilot study of alternating vincristine/doxorubicin/cyclophosphamide and etoposide/ifosfamide with IRS-IV in intermediate risk rhabdomyosarcoma: a report from the Children's Oncology Group

scientific article published on 01 January 2008

Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors

scientific article published on 23 January 2014

Cost minimization analysis of two treatment regimens for low-risk rhabdomyosarcoma in children: a report from the Children's Oncology Group

scientific article

Current state of pediatric sarcoma biology and opportunities for future discovery: A report from the sarcoma translational research workshop.

scientific article

Delayed primary excision with subsequent modification of radiotherapy dose for intermediate-risk rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee

scientific article published on 10 December 2014

Delayed radiotherapy following dose intensive chemotherapy for parameningeal rhabdomyosarcoma (PM-RMS) of childhood

scientific article published in April 2007

Demographic and Treatment Variables Influencing Outcome for Localized Paratesticular Rhabdomyosarcoma: Results From a Pooled Analysis of North American and European Cooperative Groups

scientific article

Dense pattern of embryonal rhabdomyosarcoma, a lesion easily confused with alveolar rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group

scientific article

Do children and adolescents with completely resected alveolar rhabdomyosarcoma require adjuvant radiation? A report from the Children's Oncology Group

scientific article published on 02 March 2020

Early response as assessed by anatomic imaging does not predict failure-free survival among patients with Group III rhabdomyosarcoma: a report from the Children's Oncology Group.

scientific article published on 18 December 2013

Early treatment failure in intermediate-risk rhabdomyosarcoma: results from IRS-IV and D9803--a report from the Children's Oncology Group

scientific article

Effect of time to resumption of chemotherapy after definitive surgery on prognosis for non-metastatic osteosarcoma

scientific article published on March 2009

Evaluation of chemotherapy response in pediatric bone sarcomas by [F-18]-fluorodeoxy-D-glucose positron emission tomography

scientific article

Ewing Sarcoma: Current Management and Future Approaches Through Collaboration

scientific article published on 24 August 2015

Expanding the Spectrum of Pediatric NTRK-rearranged Mesenchymal Tumors

scientific article published on 01 April 2019

Family history of cancer and childhood rhabdomyosarcoma: a report from the Children's Oncology Group and the Utah Population Database.

scientific article published on 23 March 2015

Fusion-negative alveolar rhabdomyosarcoma: modification of risk stratification is premature

scientific article published on 09 August 2010

Ganglioside GD2 expression is maintained upon recurrence in patients with osteosarcoma

scientific article

Genome-Informed Targeted Therapy for Osteosarcoma

scientific article published on 28 September 2018

Germline Cancer-Predisposition Variants in Pediatric Rhabdomyosarcoma: A Report from the Children's Oncology Group

scientific article published on 29 December 2020

High-Dose Chemotherapy Compared With Standard Chemotherapy and Lung Radiation in Ewing Sarcoma With Pulmonary Metastases: Results of the European Ewing Tumour Working Initiative of National Groups, 99 Trial and EWING 2008

scientific article published on 25 September 2019

High-Dose Chemotherapy and Blood Autologous Stem-Cell Rescue Compared With Standard Chemotherapy in Localized High-Risk Ewing Sarcoma: Results of Euro-E.W.I.N.G.99 and Ewing-2008

article by Jeremy Whelan et al published 6 September 2018 in Journal of Clinical Oncology

Histologic and clinical characteristics can guide staging evaluations for children and adolescents with rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee

scientific article published on 12 August 2013

Histology, Fusion Status, and Outcome in Alveolar Rhabdomyosarcoma With Low-Risk Clinical Features: A Report From the Children's Oncology Group

scientific article

Histology, fusion status, and outcome in metastatic rhabdomyosarcoma: A report from the Children's Oncology Group.

scientific article

Impact of Local Control and Surgical Lymph Node Evaluation in Localized Paratesticular Rhabdomyosarcoma: A Report from the Children's Oncology Group Soft Tissue Sarcoma Committee

scientific article published on 11 June 2020

Impact of Two Measures of Micrometastatic Disease on Clinical Outcomes in Patients with Newly Diagnosed Ewing Sarcoma: A Report from the Children's Oncology Group

scientific article published on 09 February 2016

Increased local failure for patients with intermediate-risk rhabdomyosarcoma on ARST0531: A report from the Children's Oncology Group

scientific article published on 07 June 2019

Infantile NTRK-associated Mesenchymal Tumors.

scientific article published in January 2017

Influence of noncompliance with radiation therapy protocol guidelines and operative bed recurrences for children with rhabdomyosarcoma and microscopic residual disease: a report from the Children's Oncology Group

scientific article published on 18 June 2010

Inhaled granulocyte-macrophage colony stimulating factor for first pulmonary recurrence of osteosarcoma: effects on disease-free survival and immunomodulation. a report from the Children's Oncology Group

scientific article

Insights into pediatric rhabdomyosarcoma research: Challenges and goals

scientific article published on 21 June 2019

Integrative Bayesian Analysis Identifies Rhabdomyosarcoma Disease Genes

scientific article published on 01 July 2018

Intensive Induction Chemotherapy and Delayed Irradiation in the Management of Parameningeal Rhabdomyosarcoma ⬇️

scientific article published on October 1, 2003

Intensive Multiagent Therapy, Including Dose-Compressed Cycles of Ifosfamide/Etoposide and Vincristine/Doxorubicin/Cyclophosphamide, Irinotecan, and Radiation, in Patients With High-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group

scientific article published on 26 October 2015

Introducing INSTRuCT: An international effort to promote cooperation and data sharing

scientific article published on 12 September 2020

Local Control for Intermediate-Risk Rhabdomyosarcoma: Results From D9803 According to Histology, Group, Site, and Size: A Report From the Children's Oncology Group

scientific article published on 05 September 2015

Local control and outcome in children with localized vaginal rhabdomyosarcoma: a report from the Soft Tissue Sarcoma committee of the Children's Oncology Group

scientific article

Local control with reduced-dose radiotherapy for low-risk rhabdomyosarcoma: a report from the Children's Oncology Group D9602 study

scientific article published on 19 November 2011

Local therapy for rhabdomyosarcoma of the hands and feet: is amputation necessary? A report from the Children's Oncology Group

scientific article

Local treatment of rhabdomyosarcoma of the female genital tract: Expert consensus from the Children's Oncology Group, the European Soft-Tissue Sarcoma Group, and the Cooperative Weichteilsarkom Studiengruppe

scientific article published on 06 August 2020

Localized vaginal/uterine rhabdomyosarcoma-results of a pooled analysis from four international cooperative groups

scientific article published on 21 May 2018

MRI and CT of Low-Grade Fibromyxoid Sarcoma in Children: A Report From Children's Oncology Group Study ARST0332.

scientific article

Maternal and birth characteristics and childhood rhabdomyosarcoma: a report from the Children's Oncology Group

scientific article

Metabolic response as assessed by <sup>18</sup> F-fluorodeoxyglucose positron emission tomography-computed tomography does not predict outcome in patients with intermediate- or high-risk rhabdomyosarcoma: A report from the Children's Oncology Group

scientific article published on 19 December 2020

Minimal residual disease detected prior to hematopoietic cell transplantation

scientific article published on 02 March 2011

Myogenin, AP2β, NOS-1, and HMGA2 are surrogate markers of fusion status in rhabdomyosarcoma: a report from the soft tissue sarcoma committee of the children's oncology group

scientific article

Opportunities for Improvement in Pathology Reporting of Childhood Nonrhabdomyosarcoma Soft Tissue Sarcomas:  A Report From Children's Oncology Group (COG) Study ARST0332.

scientific article

Outcome of Patients With Recurrent Osteosarcoma Enrolled in Seven Phase II Trials Through Children's Cancer Group, Pediatric Oncology Group, and Children's Oncology Group: Learning From the Past to Move Forward

scientific article

Outcome of patients with localized orbital sarcoma who relapsed following treatment on Intergroup Rhabdomyosarcoma Study Group (IRSG) Protocols‐III and ‐IV, 1984–1997: A report from the Children's Oncology Group ⬇️

scientific article published on 07 September 2012

PAX-FOXO1fusion status drives unfavorable outcome for children with rhabdomyosarcoma: A children's oncology group report ⬇️

scientific article published on March 22, 2013

Pathological response in children and adults with large unresected intermediate-grade or high-grade soft tissue sarcoma receiving preoperative chemoradiotherapy with or without pazopanib (ARST1321): a multicentre, randomised, open-label, phase 2 tri

scientific article published on 20 July 2020

Pathology of childhood rhabdomyosarcoma: A consensus opinion document from the Children's Oncology Group, European Paediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe

scientific article published on 11 December 2020

Pattern of disease recurrence and prognostic factors in patients with osteosarcoma treated with contemporary chemotherapy

scientific article published in December 2003

Patterns of PD-1, PD-L1, and PD-L2 expression in pediatric solid tumors

scientific article published on 10 May 2017

Patterns of chemotherapy-induced toxicities and outcome in children and adolescents with metastatic rhabdomyosarcoma: A report from the Children's Oncology Group

scientific article published on 23 March 2017

Patterns of chemotherapy-induced toxicities in younger children and adolescents with rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee

scientific article

Pediatric Cancer Data Commons: Federating and Democratizing Data for Childhood Cancer Research

scientific article published on 18 October 2021

Peripheral blood stem cell support reduces the toxicity of intensive chemotherapy for children and adolescents with metastatic sarcomas

scientific article published in September 2002

Potential pitfalls of mass spectrometry to uncover mutations in childhood soft tissue sarcoma: A report from the Children's Oncology Group

scientific article published on 19 September 2016

Preclinical rationale for entinostat in embryonal rhabdomyosarcoma

scientific article published on 21 May 2019

Prognostic Factors for Outcome in Localized Extremity Rhabdomyosarcoma. Pooled Analysis from Four International Cooperative Groups

scientific article published on 10 August 2015

Prognostic significance and tumor biology of regional lymph node disease in patients with rhabdomyosarcoma: a report from the Children's Oncology Group

scientific article

Prognostic significance of tumor response at the end of therapy in group III rhabdomyosarcoma: a report from the children's oncology group

scientific article

Randomized Phase II Trial of Bevacizumab or Temsirolimus in Combination With Chemotherapy for First Relapse Rhabdomyosarcoma: A Report From the Children's Oncology Group

scientific article published on 12 September 2019

Randomized Phase II Window Trial of Two Schedules of Irinotecan With Vincristine in Patients With First Relapse or Progression of Rhabdomyosarcoma: A Report From the Children's Oncology Group ⬇️

scientific article published on September 13, 2010

Randomized trial and pharmacokinetic study of pegfilgrastim versus filgrastim after dose-intensive chemotherapy in young adults and children with sarcomas

scientific article published on 17 November 2009

Reduction of cyclophosphamide dose for patients with subset 2 low-risk rhabdomyosarcoma is associated with an increased risk of recurrence: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group

scientific article published on 17 February 2017

Refinement of risk stratification for childhood rhabdomyosarcoma using FOXO1 fusion status in addition to established clinical outcome predictors: A report from the Children's Oncology Group

scientific article published on 27 August 2019

Regional nodal involvement and patterns of spread along in-transit pathways in children with rhabdomyosarcoma of the extremity: a report from the Children's Oncology Group

scientific article

Relationship between tumor response at therapy completion and prognosis in patients with Group III rhabdomyosarcoma: A report from the Children's Oncology Group

scientific article published on 03 February 2020

Rhabdomyosarcoma

scientific article published on 7 January 2019

Rhabdomyosarcoma in infants younger than 1 year: a report from the Children's Oncology Group

scientific article

Rhabdomyosarcoma: review of the Children's Oncology Group (COG) Soft-Tissue Sarcoma Committee experience and rationale for current COG studies

scientific article

Risk-based treatment for patients with first relapse or progression of rhabdomyosarcoma: A report from the Children's Oncology Group

scientific article published on 08 May 2019

SARC025 arms 1 and 2: A phase 1 study of the poly(ADP-ribose) polymerase inhibitor niraparib with temozolomide or irinotecan in patients with advanced Ewing sarcoma

scientific article published on 08 December 2020

Safety and efficacy of high-dose tamoxifen and sulindac for desmoid tumor in children: results of a Children's Oncology Group (COG) phase II study ⬇️

scientific article

Second Malignant Neoplasms in Rhabdomyosarcoma: Victims of Our Own Success or an Underlying Genetic Predisposition Syndrome?

scientific article published on 27 October 2015

Shorter-duration therapy using vincristine, dactinomycin, and lower-dose cyclophosphamide with or without radiotherapy for patients with newly diagnosed low-risk rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Onc

scientific article

Spotlight on the treatment of infantile fibrosarcoma in the era of neurotrophic tropomyosin receptor kinase inhibitors: International consensus and remaining controversies

scientific article published on 09 August 2020

Substitution with doxorubicin for daunorubicin during induction for high risk pediatric acute lymphoblastic leukemia results in increased toxicity ⬇️

scientific article published on September 26, 2012

Surgery alone is sufficient therapy for children and adolescents with low-risk synovial sarcoma: A joint analysis from the European paediatric soft tissue sarcoma Study Group and the Children's Oncology Group.

scientific article published on 6 April 2017

Surgical management of extremity rhabdomyosarcoma: A consensus opinion from the Children's Oncology Group, the European Pediatric Soft-Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe

scientific article published on 09 August 2020

Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort

scientific article published on 25 January 2019

Survival outcomes of patients with localized FOXO1 fusion-positive rhabdomyosarcoma treated on recent clinical trials: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group

scientific article published on 20 November 2020

Targeting oxidative stress in embryonal rhabdomyosarcoma.

scientific article published on December 2013

The HDAC3–SMARCA4–miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma

scientific article published on 20 November 2018

The Inconvenience of Convenience Cohorts: Rhabdomyosarcoma and the PAX-FOXO1 Biomarker ⬇️

scientific article published on May 7, 2012

The Role of Childhood Infections and Immunizations on Childhood Rhabdomyosarcoma: A Report From the Children's Oncology Group

scientific article

The World Health Organization Classification of Skeletal Muscle Tumors in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group

scientific article published on 19 May 2015

The addition of cixutumumab or temozolomide to intensive multiagent chemotherapy is feasible but does not improve outcome for patients with metastatic rhabdomyosarcoma: A report from the Children's Oncology Group

article

The clinical, research, and social value of autopsy after any cancer death: a perspective from the Children's Oncology Group Soft Tissue Sarcoma Committee

scientific article published on 17 October 2011

The effect of radiation timing on patients with high-risk features of parameningeal rhabdomyosarcoma: an analysis of IRS-IV and D9803.

scientific article published in November 2013

The prognostic significance of anaplasia in childhood rhabdomyosarcoma: A report from the Children's Oncology Group

scientific article published on 07 December 2020

The use of neoadjuvant larotrectinib in the management of children with locally advanced TRK fusion sarcomas

scientific article published on 11 September 2018

Thyroid Cancer in the Pediatric Population

scientific article published on 18 September 2019

Topotecan by 21-day continuous infusion in children with relapsed or refractory solid tumors: a Children's Oncology Group study

scientific article

Toxicity and efficacy of intensive chemotherapy for children with acute lymphoblastic leukemia (ALL) after first bone marrow or extramedullary relapse

scientific article published in October 2004

Transcriptome analysis of desmoplastic small round cell tumors identifies actionable therapeutic targets: a report from the Children's Oncology Group

scientific article published on 23 July 2020

Treatment Approach and Outcomes in Infants With Localized Rhabdomyosarcoma: A Report From the Soft Tissue Sarcoma Committee of the Children's Oncology Group ⬇️

scientific article published on 20 August 2018

Treatment of metastatic osteosarcoma with the somatostatin analog OncoLar: significant reduction of insulin-like growth factor-1 serum levels

scientific article published in August 2002

Tumor volume and patient weight as predictors of outcome in children with intermediate risk rhabdomyosarcoma: a report from the Children's Oncology Group

scientific article

Undifferentiated Sarcomas in Children Harbor Clinically Relevant Oncogenic Fusions and Gene Copy-Number Alterations: A Report from the Children's Oncology Group

scientific article published on 24 April 2018

Use of positron emission tomography in localized extremity soft tissue sarcoma treated with neoadjuvant chemotherapy

scientific article published in January 2005

Vaginal Ewing Sarcoma: An Uncommon Clinical Entity in Pediatric Patients

scientific article

Vincristine, actinomycin, and cyclophosphamide compared with vincristine, actinomycin, and cyclophosphamide alternating with vincristine, topotecan, and cyclophosphamide for intermediate-risk rhabdomyosarcoma: children's oncology group study D9803.

scientific article published on 21 September 2009

What happened to the US cancer cooperative groups? A status update ten years after the Institute of Medicine report

scientific article published on 24 September 2020

What is new in the biology and treatment of pediatric rhabdomyosarcoma?

scientific article

[18F]Fluorodeoxyglucose positron emission tomography predicts outcome for Ewing sarcoma family of tumors

scientific article published in December 2005

[F-18]-fluorodeoxy-D-glucose-positron emission tomography response is associated with outcome for extremity osteosarcoma in children and young adults

scientific article

Paulina is supported by:

About Paulina

Help