List of works by Hira L Nakhasi

A Leishmania minicircle DNA footprint assay for sensitive detection and rapid speciation of clinical isolates

scientific article

A Leishmania-specific gene upregulated at the amastigote stage is crucial for parasite survival

scientific article published on 14 August 2018

A multiplex polymerase chain reaction microarray assay to detect bioterror pathogens in blood

scientific article published in October 2005

A new model of progressive visceral leishmaniasis in hamsters by natural transmission via bites of vector sand flies

scientific article published on 3 January 2013

A novel semiquantitative fluorescence-based multiplex polymerase chain reaction assay for rapid simultaneous detection of bacterial and parasitic pathogens from blood

scientific article published on May 2005

A novel signal sequence negative multimeric glycosomal protein required for cell cycle progression of Leishmania donovani parasites.

scientific article

A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing

scientific article published on 10 July 2020

An atypical protein disulfide isomerase from the protozoan parasite Leishmania containing a single thioredoxin-like domain

scientific article published on 9 November 2002

Application of rapid in vitro co-culture system of macrophages and T-cell subsets to assess the immunogenicity of dogs vaccinated with live attenuated Leishmania donovani centrin deleted parasites (LdCen-/-)

scientific article published on 30 April 2016

Arbitrary-primed PCR for genomic fingerprinting and identification of differentially regulated genes in Indian isolates of Leishmania donovani

article

Biomarkers of safety and immune protection for genetically modified live attenuated leishmania vaccines against visceral leishmaniasis - discovery and implications

scientific article

Centrin gene disruption impairs stage-specific basal body duplication and cell cycle progression in Leishmania

scientific article published on 14 April 2004

Centrin-Deleted Leishmania donovani Parasites Help CD4+ T Cells to Acquire Th1 Phenotype and Multi-Functionality Through Downregulation of CD200-CD200R Immune Inhibitory Axis.

scientific article published on 4 June 2018

Centrin1 is required for organelle segregation and cytokinesis in Trypanosoma brucei

scientific article published on 13 June 2007

Centrins, cell cycle regulation proteins in human malaria parasite Plasmodium falciparum

scientific article (publication date: 14 November 2008)

Characterization of a Leishmania stage-specific mitochondrial membrane protein that enhances the activity of cytochrome c oxidase and its role in virulence

scientific article

Characterization of cross-protection by genetically modified live-attenuated Leishmania donovani parasites against Leishmania mexicana.

scientific article

Cloning and characterization of angiotensin converting enzyme related dipeptidylcarboxypeptidase from Leishmania donovani

scientific article

Comparative in vivo expression of amastigote up regulated Leishmania genes in three different forms of Leishmaniasis

article

DNA polymorphism assay distinguishes isolates of Leishmania donovani that cause kala-azar from those that cause post-kala-azar dermal Leishmaniasis in humans

scientific article

Deletion of mitochondrial associated ubiquitin fold modifier protein Ufm1 in Leishmania donovani results in loss of β-oxidation of fatty acids and blocks cell division in the amastigote stage

scientific article

Deletion of ubiquitin fold modifier protein Ufm1 processing peptidase Ufsp in L. donovani abolishes Ufm1 processing and alters pathogenesis

scientific article (publication date: February 2014)

Development of an aptamer-based concentration method for the detection of Trypanosoma cruzi in blood

scientific article (publication date: 2012)

Differential Role of Leptin as an Immunomodulator in Controlling Visceral Leishmaniasis in Normal and Leptin-Deficient Mice

scientific article published on 25 April 2016

Downregulation of mitogen-activated protein kinase 1 of Leishmania donovani field isolates is associated with antimony resistance

scientific article published on 7 November 2011

Essential Role of Neutrophils in the Protective Immune Response Induced by a Live Attenuated Leishmania Vaccine

scientific article published on 11 November 2020

Expression of calreticulin P-domain results in impairment of secretory pathway in Leishmania donovani and reduced parasite survival in macrophages.

scientific article published in October 2002

FDA workshop on emerging infectious diseases: evaluating emerging infectious diseases (EIDs) for transfusion safety

scientific article published on 10 March 2011

Gene deleted live attenuated Leishmania vaccine candidates against visceral leishmaniasis elicit pro-inflammatory cytokines response in human PBMCs.

scientific article published on 14 September 2016

Generation of growth arrested Leishmania amastigotes: a tool to develop live attenuated vaccine candidates against visceral leishmaniasis

scientific article published on 14 May 2014

Genetic diversity of Leishmania donovani that causes cutaneous leishmaniasis in Sri Lanka: a cross sectional study with regional comparisons.

scientific article published on 22 December 2017

Genetically Modified Live Attenuated Leishmania donovani Parasites Induce Innate Immunity through Classical Activation of Macrophages That Direct the Th1 Response in Mice

scientific article

Genetically modified live attenuated parasites as vaccines for leishmaniasis

scientific article published on March 2006

Gut Microbes Egested during Bites of Infected Sand Flies Augment Severity of Leishmaniasis via Inflammasome-Derived IL-1β.

scientific article published on 27 December 2017

Heme Oxygenase-1 Induction by Blood-Feeding Arthropods Controls Skin Inflammation and Promotes Disease Tolerance

scientific article published on 01 October 2020

Identification and characterization of genes involved in leishmania pathogenesis: the potential for drug target selection

scientific article

Immunity to visceral leishmaniasis using genetically defined live-attenuated parasites

scientific article

Immunization with Live Attenuated Leishmania donovani Centrin-/- Parasites Is Efficacious in Asymptomatic Infection

scientific article

Innovations for the elimination and control of visceral leishmaniasis

scientific article published on 19 September 2019

International survey on the impact of parasitic infections: frequency of transmission and current mitigation strategies

scientific article published on 06 December 2018

Intracellular replication-deficient Leishmania donovani induces long lasting protective immunity against visceral leishmaniasis.

scientific article published on 10 July 2009

Intradermal Immunization of Leishmania donovani Centrin Knock-Out Parasites in Combination with Salivary Protein LJM19 from Sand Fly Vector Induces a Durable Protective Immune Response in Hamsters.

scientific article published on 11 January 2016

Leishmania donovani argininosuccinate synthase is an active enzyme associated with parasite pathogenesis

scientific article

Leptin Functions in Infectious Diseases

scholarly article by Radheshyam Maurya et al published 26 November 2018 in Frontiers in Immunology

Live Attenuated Leishmania donovani Centrin Gene-Deleted Parasites Induce IL-23-Dependent IL-17-Protective Immune Response against Visceral Leishmaniasis in a Murine Model

scientific article published on 29 November 2017

Live Attenuated Leishmania donovani Centrin Knock Out Parasites Generate Non-inferior Protective Immune Response in Aged Mice against Visceral Leishmaniasis

scientific article

Live attenuated Leishmania donovani p27 gene knockout parasites are nonpathogenic and elicit long-term protective immunity in BALB/c mice

scientific article published on 21 January 2013

Ly6Chi inflammatory monocytes promote susceptibility to Leishmania donovani infection

scientific article published on 31 October 2017

Lymphocytes influence Leishmania major pathogenesis in a strain-dependent manner

scientific article published on 18 November 2019

Methods to Evaluate the Preclinical Safety and Immunogenicity of Genetically Modified Live-Attenuated Leishmania Parasite Vaccines

scientific article published in January 2016

Microarray multiplex assay for the simultaneous detection and discrimination of hepatitis B, hepatitis C, and human immunodeficiency type-1 viruses in human blood samples

scientific article published on 26 March 2007

Mitochondrial associated ubiquitin fold modifier-1 mediated protein conjugation in Leishmania donovani

scientific article

Modulation of Innate Immune Mechanisms to Enhance Leishmania Vaccine-Induced Immunity: Role of Coinhibitory Molecules

scientific article

Multiple Antigen Peptide Vaccines againstPlasmodium falciparumMalaria ⬇️

scientific article published on September 7, 2010

Multiplex detection and identification of viral, bacterial, and protozoan pathogens in human blood and plasma using a high-density resequencing pathogen microarray platform

scientific article

Multiplex screening for blood-borne viral, bacterial, and protozoan parasites using an OpenArray platform

scientific article published on 30 October 2013

Neutrophil-dendritic cell interaction plays an important role in live attenuated Leishmania vaccine induced immunity

scientific article published on 22 February 2022

Overexpression of histone H2A modulates drug susceptibility in Leishmania parasites

scientific article published on 27 April 2010

Programmed cell death in trypanosomatids and other unicellular organisms

scientific article

Programmed cell death in trypanosomatids: is it an altruistic mechanism for survival of the fittest?

scientific article

Research priorities for elimination of visceral leishmaniasis

scientific article published on December 2014

Role of Mast Cells in clearance of Leishmania through extracellular trap formation

scientific article published on 16 October 2017

Role of centrins 2 and 3 in organelle segregation and cytokinesis in Trypanosoma brucei

scientific article

Role of pro-inflammatory cytokine IL-17 in Leishmania pathogenesis and in protective immunity by Leishmania vaccines

scientific article

Screening of Blood Donations for Zika Virus Infection - Puerto Rico, April 3-June 11, 2016

scientific article

TACI deficiency leads to alternatively activated macrophage phenotype and susceptibility to Leishmania infection

scientific article published on 13 July 2015

Targeted Immunology for Prevention and Cure of VL.

scientific article published on 19 December 2014

The application of gene expression microarray technology to kinetoplastid research

scientific article published in September 2004

Transfusion-transmitted babesiosis in the United States: summary of a workshop

scientific article published on 10 October 2009

Upregulation of surface proteins in Leishmania donovani isolated from patients of post kala-azar dermal leishmaniasis

article

Vaccination using live attenuated Leishmania donovani centrin deleted parasites induces protection in dogs against Leishmania infantum

scientific article

Whole genome sequencing of live attenuated Leishmania donovani parasites reveals novel biomarkers of attenuation and enables product characterization

scientific article published on 5 July 2017

miR-21 Expression Determines the Early Vaccine Immunity Induced by LdCen -/- Immunization

scientific article published on 24 September 2019

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