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List of works by Shyam K Sharan

Bypass of premature stop codons and generation of functional BRCA2 by exon skipping

scientific article published on 11 May 2020

Calibration of pathogenicity due to variant-induced leaky splicing defects by using BRCA2 exon 3 as a model system

scientific article published on 08 July 2020

Degradation of 5hmC-marked stalled replication forks by APE1 causes genomic instability

scientific article published on 18 August 2020

Epidemiological and ES cell-based Functional Evaluation of BRCA2 Variants Identified in Families with Breast Cancer

scientific article published on 13 December 2020

Exploring role of 5hmC as potential marker of chemoresistance

scientific article published on 22 October 2020

Functional evaluation of five BRCA2 unclassified variants identified in a Sri Lankan cohort with inherited cancer syndromes using a mouse embryonic stem cell-based assay

scientific article published on 11 May 2020

Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy

scientific article published on 13 April 2020

The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation

scientific article published on 10 June 2021

Variants of uncertain clinical significance in hereditary breast and ovarian cancer genes: best practices in functional analysis for clinical annotation

scientific article published on 09 March 2020

WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells

scientific article published on 12 November 2021

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