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List of works by Jeffrey S Hyams

A review of activity indices and end points for clinical trials in children with Crohn's disease

scientific article

Age of diagnosis influences serologic responses in children with Crohn's disease: a possible clue to etiology?

scientific article published on May 2009

Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis

scientific article published in March 2019

Analysis of Using the Total White Blood Cell Count to Define Severe New Onset Ulcerative Colitis in Children

scientific article published on 09 June 2020

Appraisal of the pediatric ulcerative colitis activity index (PUCAI)

scientific article published on 01 August 2009

Assessing disease activity in ulcerative colitis: patients or their physicians?

scientific article published on 01 April 2010

Association Between Plasma Level of Collagen Type III alpha 1 Chain and Development of Strictures in Pediatric Patients With Crohn's Disease

scientific article published on 10 September 2018

Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation

scientific article published on 16 February 2019

C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) or both? A systematic evaluation in pediatric ulcerative colitis

scientific article published on 2 June 2011

Challenges in pediatric inflammatory bowel disease

scientific article published on September 2006

Characterization of Stool Virome in Children Newly Diagnosed With Moderate to Severe Ulcerative Colitis

scientific article published on 01 September 2019

Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients with Crohn's Disease

scientific article published on 15 February 2018

Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study

scientific article published on 29 March 2019

Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course

article

Consensus for managing acute severe ulcerative colitis in children: a systematic review and joint statement from ECCO, ESPGHAN, and the Porto IBD Working Group of ESPGHAN.

scientific article published on 11 January 2011

Corrigendum. Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

scientific article published on 2 March 2015

Corticosteroid Therapy in the Age of Infliximab: Acute and 1-Year Outcomes in Newly Diagnosed Children With Crohn’s Disease

scientific article published on 24 July 2006

Course and Treatment of Perianal Disease in Children Newly Diagnosed with Crohnʼs Disease

scientific article published on 01 March 2009

Designing clinical trials in paediatric inflammatory bowel diseases: a PIBDnet commentary

scientific article published on 12 April 2019

Development, validation, and evaluation of a pediatric ulcerative colitis activity index: a prospective multicenter study

scientific article published on 21 May 2007

Differentiating ulcerative colitis from Crohn disease in children and young adults: report of a working group of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Crohn's and Colitis Foundation of America

scientific article published on May 2007

Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping

scientific article published on 22 June 2015

Effect of early immunomodulator use in moderate to severe pediatric Crohn disease

scientific article

Enhanced Contribution of HLA in Pediatric Onset Ulcerative Colitis

scientific article

Evaluation of the Pediatric Crohn Disease Activity Index: A Prospective Multicenter Experience

article

Extraintestinal manifestations of pediatric inflammatory bowel disease and their relation to disease type and severity

scientific article published in August 2010

Factors That Determine Risk for Surgery in Pediatric Patients With Crohn's Disease

scientific article published on 31 May 2010

Factors associated with early outcomes following standardised therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study

scientific article published on 19 September 2017

Free and Bioavailable 25-Hydroxyvitamin D Concentrations are Associated With Disease Activity in Pediatric Patients With Newly Diagnosed Treatment Naïve Ulcerative Colitis.

scientific article published in February 2018

Gene expression changes associated with resistance to intravenous corticosteroid therapy in children with severe ulcerative colitis

scientific article

Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease

scientific article published on 01 February 2019

Genetic variants and pathways implicated in a pediatric inflammatory bowel disease cohort.

scientific article published on 28 March 2018

Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease.

scientific article published on 28 September 2016

Glucocorticoid bioactivity does not predict response to steroid therapy in severe pediatric ulcerative colitis

scientific article published in March 2010

Growth Abnormalities Persist in Newly Diagnosed Children With Crohn Disease Despite Current Treatment Paradigms

scientific article published on 01 February 2009

Growth Improvement with Adalimumab Treatment in Children with Moderately to Severely Active Crohn's Disease.

scientific article published on 15 March 2017

Health-related quality of life in the first year after a diagnosis of pediatric inflammatory bowel disease

article

Histologic Correlates of Clinical and Endoscopic Severity in Children Newly Diagnosed With Ulcerative Colitis.

scientific article published on 31 August 2017

Improvement in Biomarkers of Bone Formation During Infliximab Therapy in Pediatric Crohn's Disease: Results of the REACH Study

article

Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease

scientific article

Induction and Maintenance Therapy With Infliximab for Children With Moderate to Severe Ulcerative Colitis ⬇️

scientific article published on December 8, 2011

Induction and maintenance infliximab therapy for the treatment of moderate-to-severe Crohn's disease in children

scientific article published on 3 December 2006

Infliximab Is Not Associated With Increased Risk of Malignancy or Hemophagocytic Lymphohistiocytosis in Pediatric Patients With Inflammatory Bowel Disease

scientific article published on 10 February 2017

Infliximab therapy in children with concurrent perianal Crohn disease: observations from REACH

scientific article published on 01 August 2009

Laboratory values for children with newly diagnosed inflammatory bowel disease

scientific article

Long ncRNA Landscape in the Ileum of Treatment-Naive Early-Onset Crohn Disease.

scientific article published in January 2018

Long-term outcome of maintenance infliximab therapy in children with Crohnʼs disease

scientific article published on 01 June 2009

Longitudinal non-adherence predicts treatment escalation in paediatric ulcerative colitis

scientific article published on 02 August 2019

Machine learning identifies novel blood protein predictors of penetrating and stricturing complications in newly diagnosed paediatric Crohn's disease

scientific article published on 01 November 2020

Magnetic Resonance Enterography Cannot Replace Upper Endoscopy in Pediatric Crohn's Disease: An Imagekids Sub-study

scientific article published on 28 December 2017

Microbiota-sensitive epigenetic signature predicts inflammation in Crohn's disease

Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-Only Crohn's Disease in Treatment-Naive Pediatric Patients

scientific article

Mucosal Inflammatory and Wound Healing Gene Programs Reveal Targets for Stricturing Behavior in Pediatric Crohn's Disease

scientific article published on 08 August 2020

Pediatric Crohn disease patients exhibit specific ileal transcriptome and microbiome signature

scientific article

Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study

scientific article published on March 2017

Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets.

scientific article published on 29 January 2019

Real-time tool to display the predicted disease course and treatment response for children with Crohn's disease

scientific article

Retrospective Evaluation of the Safety and Effect of Adalimumab Therapy (RESEAT) in pediatric Crohn's disease

scientific article published on September 2009

Safety and efficacy of maintenance infliximab therapy for moderate-to-severe Crohn’s disease in children: REACH open-label extension ⬇️

scientific article published on January 18, 2011

Serologic Reactivity Reflects Clinical Expression of Ulcerative Colitis in Children

scientific article published on 01 May 2018

Serum Protein Biomarkers of Fibrosis Aid in Risk Stratification of Future Stricturing Complications in Pediatric Crohn's Disease

scientific article published on 01 May 2019

Severe pediatric ulcerative colitis: a prospective multicenter study of outcomes and predictors of response

scientific article published on 26 February 2010

The Effect of Early-Life Environmental Exposures on Disease Phenotype and Clinical Course of Crohn's Disease in Children

scientific article published on 28 September 2018

The Natural History of Corticosteroid Therapy for Ulcerative Colitis in Children

scientific article published on 03 July 2006

The effects of concomitant immunomodulators on the pharmacokinetics, efficacy and safety of adalimumab in paediatric patients with Crohn's disease: a post hoc analysis

scientific article published on 02 December 2018

The treatment-naive microbiome in new-onset Crohn's disease

scientific article

Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease

scientific article published on 14 August 2017

Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response

scientific article published in Nature Communications

Utility of neutrophil Fcγ receptor I (CD64) index as a biomarker for mucosal inflammation in pediatric Crohn's disease

scientific article

Variation in Care in the Management of Children With Crohn's Disease: Data From a Multicenter Inception Cohort Study

scientific article published on 01 June 2019

Which PCDAI Version Best Reflects Intestinal Inflammation in Pediatric Crohn Disease?

scientific article published on 4 April 2016

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