List of works - Johannes Oldenburg

A common F13A1 intron 1 variant IVS1+12(A) is associated with mild FXIII deficiency in Caucasian population ⬇️

scientific article published on March 19, 2013

A new cell culture-based assay quantifies vitamin K 2,3-epoxide reductase complex subunit 1 function and reveals warfarin resistance phenotypes not shown by the dithiothreitol-driven VKOR assay ⬇️

scientific article published on May 1, 2013

AHEAD. Advate in HaEmophilia A outcome Database

scientific article published on November 1, 2010

Acquired deficiency of coagulation factor XIII—possible evidence for a new link between coagulation and infection from a case ⬇️

scientific article published on September 28, 2012

Acute Hepatitis E Virus infection in a hemophilic patient with acquired inhibitor during immune tolerance therapy according to modified Bonn-Malmö protocol

scientific article published on 29 January 2019

Acute hepatitis C in haemophiliacs due to "virus-inactivated" clotting factor concentrates

scientific article published on 01 December 1992

Analysis of F8 mRNA in haemophilia A patients with silent mutations or presumptive splice site mutations ⬇️

scientific article published on October 23, 2012

Association between phenotype and genotype in carriers of haemophilia A ⬇️

scientific article published on December 1, 2010

Association of COMT genotypes with S-COMT promoter methylation in growth-discordant monozygotic twins and healthy adults ⬇️

scientific article published on September 1, 2011

Cancer risk in HIV-infected individuals on HAART is largely attributed to oncogenic infections and state of immunocompetence ⬇️

scientific article published on March 28, 2011

Challenges and key lessons from the design and implementation of an international haemophilia registry supported by a pharmaceutical company

scientific article published on 23 October 2020

Characterization of duplication breakpoints in the factor VIII gene ⬇️

scientific article published on December 1, 2010

Characterization of the mutation spectrum in a Pakistani cohort of type 3 von Willebrand disease

scientific article published on 18 September 2019

Coincidence of 2 severe chronic diseases: presymptomatic diagnosis of Wilson disease in a boy with severe haemophilia A ⬇️

scientific article published on May 24, 2013

Comprehensive Care Center Bonn from 1980 to 2009. Changes in the epidemiology and regional composition of the haemophilia population ⬇️

scientific article published on 01 November 2011

Congenital and acquired bleeding disorders: the right factor for the right patient ⬇️

scientific article published on 01 December 2012

Deficiencies of antithrombin, protein C and protein S – Practical experience in genetic analysis of a large patient cohort ⬇️

scientific article published on May 25, 2012

Determination of the warfarin inhibition constant Ki for vitamin K 2,3-epoxide reductase complex subunit-1 (VKORC1) using an in vitro DTT-driven assay ⬇️

scientific article published on April 22, 2013

Disruption of Structural Disulfides of Coagulation FXIII-B Subunit; Functional Implications for a Rare Bleeding Disorder

scientific article published on 22 April 2019

Elastin Polymorphism Haplotype and Intracranial Aneurysms Are Not Associated in Central Europe ⬇️

scientific article published on April 10, 2003

Elevated Interleukin-6 Concentration and Alterations of the Coagulation System Are Associated with the Development of Intraventricular Hemorrhage in Extremely Preterm Infants ⬇️

scientific article published on August 18, 2012

Estimation of Nuwiq® (simoctocog alfa) activity using one-stage and chromogenic assays-Results from an international comparative field study

scientific article published on 20 May 2019

Evidence for mast cell activation in patients with therapy-resistant irritable bowel syndrome ⬇️

scientific article published on February 4, 2011

Exploring Diverse Coagulation Factor XIII Subunit Expression Datasets: A Bioinformatic Analysis

scientific article published on 25 April 2022

Extracorporeal Treatment for the Acute und Long-Term Outcome of Patients with Life-Threatening Acquired Hemophilia ⬇️

scientific article published on July 26, 2012

Factor VIII gene mutations found by a comparative study of SSCP, DGGE and CMC and their analysis on a molecular model of factor VIII protein ⬇️

scientific article published on December 1, 1997

Health-related quality of life and caregiver burden of emicizumab in children with haemophilia A and factor VIII inhibitors-Results from the HAVEN 2 study

scientific article published on 21 October 2020

Health-related quality of life and health status in persons with haemophilia A with inhibitors: A prospective, multicentre, non-interventional study (NIS)

scientific article published on 24 April 2019

High adherence to prophylaxis regimens in haemophilia B patients receiving rIX-FP: Evidence from clinical trials and real-world practice

scientific article published on 15 June 2020

Homo erectus haemophilus - the haemophilic arthropathy of the leg

scientific article published on 01 November 2011

Human Vitamin K 2,3-Epoxide Reductase Complex Subunit 1-like 1 (VKORC1L1) Mediates Vitamin K-dependent Intracellular Antioxidant Function ⬇️

scientific article published on March 2, 2011

Identification of VKORC1 interaction partners by split-ubiquitin system and coimmunoprecipitation ⬇️

scientific article published on November 23, 2010

Impact of pharmacokinetic (CYP2C9) and pharmacodynamic (VKORC1, F7, GGCX, CALU, EPHX1) gene variants on the initiation and maintenance phases of phenprocoumon therapy

scientific article published on 05 November 2010

In VitroSecretion Deficits are Common Among Human Coagulation Factor XIII Subunit B Missense Mutants: Correlations with Patient Phenotypes and Molecular Models ⬇️

scientific article published on September 13, 2013

In vitro characterization of recombinant factor VIII concentrates reveals significant differences in protein content, activity and thrombin activation profile ⬇️

scientific article published on December 18, 2012

Increased circulating levels of neurotrophins and elevated expression of their high-affinity receptors on skin and gut mast cells in mastocytosis ⬇️

scientific article published on July 18, 2013

Increased sensitivity of factor IX to phenprocoumon as a cause of bleeding in a patient with antiphospholipid antibody associated thrombosis ⬇️

scientific article published on January 1, 1998

Insights into pathological mechanisms of missense mutations in C-terminal domains of von Willebrand factor causing qualitative or quantitative von Willebrand disease ⬇️

scientific article published on March 28, 2013

Intron retention resulting from a silent mutation in the VWF gene that structurally influences the 5' splice site

scientific article published on 19 August 2016

Large deletions identified in patients with von Willebrand disease using multiple ligation‐dependent probe amplification ⬇️

scientific article published on May 1, 2011

Long-term therapy and on-demand treatment of children and adolescents with severe haemophilia A: 12 years of experience

scientific article published on January 1, 1992

Measurements of DNA Methylation at Seven Loci in Various Tissues of CD1 Mice ⬇️

scientific article published on September 7, 2012

Methylation Levels at Selected CpG Sites in the Factor VIII and FGFR3 Genes, in Mature Female and Male Germ Cells: Implications for Male-Driven Evolution ⬇️

scientific article published on October 1, 1998

Methylation at Global LINE-1 Repeats in Human Blood Are Affected by Gender but Not by Age or Natural Hormone Cycles ⬇️

scientific article published on January 19, 2011

Mild haemophilia A in a female patient with a large X‐chromosomal deletion and a missense mutation in the F8 gene – a case report ⬇️

scientific article published on May 28, 2013

Missense mutations at ALA‐10 in the factor IX propeptide: an insignificant variant in normal life but a decisive cause of bleeding during oral anticoagulant therapy ⬇️

scientific article published on July 1, 1997

Molecular analysis of FVIII gene in severe HA patients of Costa Rica

scientific article published on November 1, 2010

Molecular basis of antithrombin deficiency ⬇️

scientific article published on January 25, 2011

Molecular genetic analysis of a patient with moderate hemophilia A and psychomotor developmental delay ⬇️

scientific article published on May 24, 2013

Multifaceted pathomolecular mechanism of a VWF large deletion involved in the pathogenesis of severe VWD

scientific article published on 01 February 2022

Mutations in severe hemophilia A: distribution within the factor VIII gene, origin and influence on inhibitor development

scientific article published on January 1, 1997

NKG2D Engagement Alone Is Sufficient to Activate Cytokine-Induced Killer Cells While 2B4 Only Provides Limited Coactivation

scientific article published on 07 October 2021

Optimal treatment strategies for hemophilia: achievements and limitations of current prophylactic regimens

scientific article

Optimizing the management of patients with haemophilia A and inhibitors in the era of emicizumab: Recommendations from a German expert panel

scientific article published on 16 September 2020

Prediction of phenprocoumon maintenance dose and phenprocoumon plasma concentration by genetic and non-genetic parameters ⬇️

scientific article published on November 26, 2010

Profiling of Active Thrombin in Human Blood by Supramolecular Complexes ⬇️

scientific article published on May 17, 2011

Prophylaxis in bleeding disorders ⬇️