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List of works by Klaus-Peter Janssen

A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations

scientific article

APC inactivation associates with abnormal mitosis completion and concomitant BUB1B/MAD2L1 up-regulation

scientific article

An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer

scientific article published on 2 September 2015

Blood-based detection of RAS mutations to guide anti-EGFR therapy in colorectal cancer patients: concordance of results from circulating tumor DNA and tissue-based RAS testing

scientific article published on 16 November 2016

Colorectal cancer surgery remains effective with rising patient age.

scientific article

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling

scientific article published on 30 June 2015

Distribution and quantification of irinotecan and its active metabolite SN-38 in colon cancer murine model systems using MALDI MSI.

scientific article

Epithelial morphogenesis and intestinal cancer: new insights in signaling mechanisms

scientific article published on January 2008

Expression of the mitotic checkpoint gene MAD2L2 has prognostic significance in colon cancer

scientific article

Fascin, a novel target of beta-catenin-TCF signaling, is expressed at the invasive front of human colon cancer

scientific article (publication date: 15 July 2007)

Gastric Adenocarcinomas Express the Glycosphingolipid Gb3/CD77: Targeting of Gastric Cancer Cells with Shiga Toxin B-Subunit

scientific article published on 29 January 2016

Gut bacterial dysbiosis and instability is associated with the onset of complications and mortality in COVID-19

scientific article published on 01 January 2022

High-mass-resolution MALDI mass spectrometry imaging of metabolites from formalin-fixed paraffin-embedded tissue

scientific article

High-resolution MALDI-FT-ICR MS imaging for the analysis of metabolites from formalin-fixed, paraffin-embedded clinical tissue samples

scientific article published on 30 June 2015

IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival.

scientific article

Immunoinhibitory Adapter Protein Src Homology Domain 3 Lymphocyte Protein 2 (SLy2) Regulates Actin Dynamics and B Cell Spreading ⬇️

scientific article published on February 4, 2011

In vivo tumor targeting via nanoparticle-mediated therapeutic siRNA coupled to inflammatory response in lung cancer mouse models.

scientific article published on 12 July 2013

Independent validation of a prognostic genomic signature (ColoPrint) for patients with stage II colon cancer

scientific article

MicroRNA classifier and nomogram for metastasis prediction in colon cancer.

scientific article

Mitochondrial function controls intestinal epithelial stemness and proliferation

scientific article published on 27 October 2016

Mouse models of K-ras-initiated carcinogenesis

scientific article

Mucinous and signet-ring cell colorectal cancers differ from classical adenocarcinomas in tumor biology and prognosis

scientific article

Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

scientific journal article

Novel role for CRK adaptor proteins as essential components of SRC/FAK signaling for epithelial-mesenchymal transition and colorectal cancer aggressiveness

scientific article published on 09 March 2020

Outcome after surgery for acute right-sided colonic ischemia without feasible vascular intervention: a single center experience of 58 patients over 6 years

scientific article

PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1

scientific article published on 14 February 2009

Prediction of metastasis and recurrence in colorectal cancer based on gene expression analysis: ready for the clinic?

scientific article published on 07 July 2011

Prognostic Impact of Modulators of G proteins in Circulating Tumor Cells from Patients with Metastatic Colorectal Cancer

scientific article published on 26 February 2016

SASH1 Is Involved in an Autosomal Dominant Lentiginous Phenotype

scientific article

SASH1, a new potential link between smoking and atherosclerosis

scientific article published on 14 August 2015

Spatial organization of the tenascin-C microenvironment in experimental and human cancer

scientific article

Structure of the N-terminal domain of the adenylyl cyclase-associated protein (CAP) from Dictyostelium discoideum

scientific article

Subcellular compartmentalization of docking protein-1 contributes to progression in colorectal cancer

scientific article published on 5 May 2016

Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneous tumorigenesis in mice

scientific article

Targeting of tumor blood vessels: a phage-displayed tumor-homing peptide specifically binds to matrix metalloproteinase-2-processed collagen IV and blocks angiogenesis in vivo

scientific article

Tenascin-C downregulates wnt inhibitor dickkopf-1, promoting tumorigenesis in a neuroendocrine tumor model

scientific article published on 17 October 2013

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane

scientific article published on 8 September 2015

The human submandibular gland: immunohistochemical analysis of SNAREs and cytoskeletal proteins

scientific article

Tissue inhibitor of metalloproteinases (TIMP)-1 creates a premetastatic niche in the liver through SDF-1/CXCR4-dependent neutrophil recruitment in mice

scientific article published on 24 November 2014

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