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List of works by Mario J Borgnia

A collaborative framework for 3D alignment and classification of heterogeneous subvolumes in cryo-electron tomography.

scientific article

Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP <sub>2</sub>

scientific article published on 13 October 2022

Automated systematic evaluation of cryo-EM specimens with SmartScope

scientific article published in 2022

Computational separation of conformational heterogeneity using cryo-electron tomography and 3D sub-volume averaging

scientific article

Controlling the SARS-CoV-2 spike glycoprotein conformation

scientific article published on 22 July 2020

Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies

scientific article published on 02 December 2019

Cryo-EM Analysis of the Conformational Landscape of Human P-glycoprotein (ABCB1) During its Catalytic Cycle.

scientific article

Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements

scientific article published on 24 January 2020

Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies

scientific article

Heat-dependent opening of TRPV1 in the presence of capsaicin

scientific article published on 08 July 2021

High-resolution structures of the SAMHD1 dGTPase homolog from Leeuwenhoekiella blandensis reveal a novel mechanism of allosteric activation by dATP

scientific article published in 2022

Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure

scientific article (publication date: 2010)

Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies

scientific article published on 17 September 2019

Regulatory switch at the cytoplasmic interface controls TRPV channel gating

scientific article published on 09 May 2019

Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel

scientific article

Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress

scientific article published on 27 August 2020

Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes

scientific article published on 15 May 2019

Targeted selection of HIV-specific antibody mutations by engineering B cell maturation

scientific article

The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage

scientific article published on 24 April 2020

Three-dimensional structures of soluble CD4-bound states of trimeric simian immunodeficiency virus envelope glycoproteins determined by using cryo-electron tomography

scientific article

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