List of works - Horst Bickel

A comparison of GP and GDS diagnosis of depression in late life among multimorbid patients - results of the MultiCare study

scientific article published on 18 June 2014

AD dementia risk in late MCI, in early MCI, and in subjective memory impairment

scientific article published on 30 January 2013

APOE e4-allele and mental work demands on cognitive decline in old age: Results from the German Study on Ageing, Cognition, and Dementia in Primary Care Patients (AgeCoDe)

scientific article published on 20 August 2020

Advance directives and power of attorney for health care in the oldest-old - results of the AgeQualiDe study

scientific article

Age-correction of test scores reduces the validity of mild cognitive impairment in predicting progression to dementia

scientific article

Age-related predictors of institutionalization: results of the German study on ageing, cognition and dementia in primary care patients (AgeCoDe).

scientific article

Agreement between self-reported and general practitioner-reported chronic conditions among multimorbid patients in primary care - results of the MultiCare Cohort Study

scientific article

Anticholinergic drug use and risk for dementia: target for dementia prevention

scientific article published on 20 October 2010

Apart from nihilism and stigma: what influences general practitioners' accuracy in identifying incident dementia?

scientific article published in November 2009

Association between multimorbidity patterns and chronic pain in elderly primary care patients: a cross-sectional observational study

scientific article

Association of the Alzheimer's disease clusterin risk allele with plasma clusterin concentration.

scientific article published in January 2011

Associations between Dementia Outcomes and Depressive Symptoms, Leisure Activities, and Social Support

scientific article

Associations between dementia and head circumference as a measure of brain reserve--results from the Bavarian School sisters study

scientific article published in April 2006

At-risk alcohol drinking in primary care patients aged 75 years and older

scientific article published on 01 December 2009

Carotid intima-media thickness progression and risk of vascular events in people with diabetes: results from the PROG-IMT collaboration

scientific article

Cerebrospinal fluid biomarkers for Alzheimer's disease: the role of apolipoprotein E genotype, age, and sex.

scientific article

Chronic kidney disease is associated with incident cognitive impairment in the elderly: the INVADE study

scientific article published on 21 May 2009

Cognitive performance before and after the onset of subjective cognitive decline in old age.

scientific article published on 02 May 2015

Cognitive reserve, homocysteine, and cognition in the Bavarian School Sisters Study

scientific article published in September 2011

Combined effects of hemoglobin A1c and C-reactive protein on the progression of subclinical carotid atherosclerosis: the INVADE study

scientific article

Complex coevolution of depression and health-related quality of life in old age.

scientific article published on 19 May 2015

Converging genetic and functional brain imaging evidence links neuronal excitability to working memory, psychiatric disease, and brain activity

scientific article

Correction: Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration

scientific article published in PLoS ONE

Current alcohol consumption and its relationship to incident dementia: results from a 3-year follow-up study among primary care attenders aged 75 years and older

scientific article published on 2 March 2011

Dementia friendly care services in general hospitals : Representative results of the general hospital study (GHoSt)

scientific article published on 6 November 2017

Depression, non-fatal stroke and all-cause mortality in old age: a prospective cohort study of primary care patients

scientific article

Depressive mood mediates the influence of social support on health-related quality of life in elderly, multimorbid patients

scientific article

Depressive symptoms and the risk of ischemic stroke in the elderly--influence of age and sex.

scientific article

Depressive symptoms as predictor of dementia versus continuous cognitive decline: a 3-year prospective study

scientific article published on 10 October 2012

Determinants of incident dementia in different old age groups: results of the prospective AgeCoDe/AgeQualiDe study

scientific article published on 23 December 2019

Differential Risk of Incident Alzheimer's Disease Dementia in Stable Versus Unstable Patterns of Subjective Cognitive Decline

scientific article published on 24 August 2016

Disentangling the complex relation of disability and depressive symptoms in old age - findings of a multicenter prospective cohort study in Germany

scientific article published on 30 January 2017

Driving status and health-related quality of life among the oldest old: a population-based examination using data from the AgeCoDe-AgeQualiDe prospective cohort study

scientific article published on 31 January 2020

Education, occupation, and dementia: the Bavarian school sisters study

scientific article published on 8 July 2009

Effect of Visual Impairment on Physical and Cognitive Function in Old Age: Findings of a Population-Based Prospective Cohort Study in Germany

scientific article published on 27 September 2016

Effect of cardiovascular and metabolic disease on cognitive test performance and cognitive change in older adults

scientific article

Effects of multiple chronic conditions on health care costs: an analysis based on an advanced tree-based regression model

scientific article

Elevated HbA1c is associated with increased risk of incident dementia in primary care patients

scientific article published on January 2015

Gender differences in the effect of social support on health-related quality of life: results of a population-based prospective cohort study in old age in Germany

scientific article published on 27 October 2015

Gene polymorphisms in prodynorphin (PDYN) are associated with episodic memory in the elderly

scientific article published on 26 May 2009

General practitioners' judgment of their elderly patients' cognitive status

scientific article published on 21 October 2009

Genetic Analysis of Association Between Calcium Signaling and Hippocampal Activation, Memory Performance in the Young and Old, and Risk for Sporadic Alzheimer Disease

scientific article published on 02 September 2015

High risk of cognitive and functional decline after postoperative delirium. A three-year prospective study

scientific article

High-sensitivity C-reactive protein at different stages of atherosclerosis: results of the INVADE study

scientific article published in May 2009

How does social support affect functional impairment in late life? Findings of a multicenter prospective cohort study in Germany

scientific article

Impact of depression on health care utilization and costs among multimorbid patients--from the MultiCare Cohort Study

scientific article

Impact of falls on depressive symptoms among the oldest old: Results from the AgeQualiDe study

scientific article published on 19 July 2018

Implementation of chronic illness care in German primary care practices--how do multimorbid older patients view routine care? A cross-sectional study using multilevel hierarchical modeling

scientific article

In Reply

Incidence and predictors of depression in non-demented primary care attenders aged 75 years and older: results from a 3-year follow-up study

scientific article published on 11 January 2013

Incidence and risk factors of delirium after hip surgery

scientific article published in October 2004

Incident Subjective Cognitive Decline Does Not Predict Mortality in the Elderly--Results from the Longitudinal German Study on Ageing, Cognition, and Dementia (AgeCoDe).

scientific article published on 14 January 2016

Individual progression of carotid intima media thickness as a surrogate for vascular risk (PROG-IMT): Rationale and design of a meta-analysis project

scientific article published on May 2010

Inflammatory markers and extent and progression of early atherosclerosis: Meta-analysis of individual-participant-data from 20 prospective studies of the PROG-IMT collaboration

scientific article

Is function in instrumental activities of daily living a useful feature in predicting Alzheimer's disease dementia in subjective cognitive decline?

scientific article published on 09 November 2018

Is the Short Form of the Mini-Mental State Examination (MMSE) a better screening instrument for dementia in older primary care patients than the original MMSE? Results of the German study on ageing, cognition, and dementia in primary care patients (

scientific article published on 30 March 2015

Late-Life Depressive Symptoms and Lifetime History of Major Depression: Cognitive Deficits are Largely Due to Incipient Dementia rather than Depression

scientific article published on August 2016

Longitudinal Predictors of Institutionalization in Old Age.

scientific article published on 14 December 2015

Longitudinal predictors of informal and formal caregiving time in community-dwelling dementia patients

scientific article published on 23 October 2015

Malperformance in verbal fluency and delayed recall as cognitive risk factors for impairment in instrumental activities of daily living.

scientific article published on 15 January 2011

Mental health in the aged: prevalence, covariates and related neuroendocrine, cardiovascular and inflammatory factors of successful aging

scientific article

Metabolic and endocrine factors in mild cognitive impairment

scientific article published on 28 January 2010

Mild cognitive impairment and quality of life in the oldest old: a closer look

scientific article published on 28 January 2020

Mild cognitive impairment in general practice: age-specific prevalence and correlate results from the German study on ageing, cognition and dementia in primary care patients (AgeCoDe)

scientific article published on 11 September 2007

Mild cognitive impairment: making headway by stepping backwards.

scientific article

Mortality in Incident Cognitive Impairment: Results of the Prospective AgeCoDe Study

scientific article

Motivational reserve: Motivation-related occupational abilities and risk of mild cognitive impairment and Alzheimer disease ⬇️

scientific article published on August 29, 2011

Normative values for carotid intima media thickness and its progression: Are they transferrable outside of their cohort of origin?

scientific article published on 8 January 2016

Obesity and associated lifestyle in a large sample of multi-morbid German primary care attendees

scientific article

Patterns of subjective memory impairment in the elderly: association with memory performance.

scientific article published on 11 July 2007

Physical activity and incident cognitive impairment in elderly persons: the INVADE study

scientific article published on 01 January 2010

Potentially inappropriate medication: Association between the use of antidepressant drugs and the subsequent risk for dementia

scientific article published on 14 September 2017

Predicting dementia in primary care patients with a cardiovascular health metric: a prospective population-based study

scientific article

Prediction of dementia by subjective memory impairment: effects of severity and temporal association with cognitive impairment.

scientific article published in April 2010

Prediction of dementia in primary care patients.

scientific article

Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration

scientific article published on 12 April 2018

Predictors of costs in dementia in a longitudinal perspective

scientific article

Predictors of institutionalisation in incident dementia--results of the German Study on Ageing, Cognition and Dementia in Primary Care Patients (AgeCoDe study).

scientific article published on 2 July 2012

Prevalence and determinants of driving habits in the oldest old: Results of the multicenter prospective AgeCoDe-AgeQualiDe study

scientific article published on 07 March 2019

Prevalence and determinants of overweight and obesity in old age in Germany

scientific article published on 14 July 2015

Prevalence and factors associated with obesity among the oldest old

scientific article published on 10 April 2020

Prevalence and risk factors for depression in non-demented primary care attenders aged 75 years and older

scientific article published on 26 March 2008

Prevalence of Anxiety Symptoms and Their Association With Loss Experience in a Large Cohort Sample of the Oldest-Old. Results of the AgeCoDe/AgeQualiDe Study

Prognosis of mild cognitive impairment in general practice: results of the German AgeCoDe study

scientific article published on March 2014

Psychiatric morbidity and low self-attentiveness in patients with environmental illness

scientific article published in January 2003

Reduction of Long‐Term Care Dependence After an 8‐Year Primary Care Prevention Program for Stroke and Dementia: The INVADE Trial ⬇️

scientific article published on August 24, 2012

Relative impact of multimorbid chronic conditions on health-related quality of life--results from the MultiCare Cohort Study

scientific article

Risk of dementia in elderly patients with the use of proton pump inhibitors

scientific article

Screening of cognitive functions and the prediction of incident dementia by means of the SIDAM

scientific article published in April 2007

Self-efficacy in multimorbid elderly patients with osteoarthritis in primary care--influence on pain-related disability

scientific article published on 6 September 2014

Self-rated health in multimorbid older general practice patients: a cross-sectional study in Germany

scientific article

Social inequalities in patient-reported outcomes among older multimorbid patients--results of the MultiCare cohort study

scientific article

Subjective Cognitive Decline May Be a Stronger Predictor of Incident Dementia in Women than in Men

scientific article published on 01 January 2019

Subjective cognitive decline is longitudinally associated with lower health-related quality of life

scientific article

Suitability of the 6CIT as a screening test for dementia in primary care patients

scholarly article by Johannes Hessler et al published 20 November 2013 in Aging and Mental Health

The 6-Item Cognitive Impairment Test as a bedside screening for dementia in general hospital patients: results of the General Hospital Study (GHoSt).

scientific article

The CERAD neuropsychological assessment battery total score detects and predicts Alzheimer disease dementia with high diagnostic accuracy

scientific article published on 4 June 2013

The German MultiCare-study: Patterns of multimorbidity in primary health care - protocol of a prospective cohort study

scientific article

The ability of general practitioners to detect dementia and cognitive impairment in their elderly patients: A study in Mannheim

scholarly article by Brian Cooper et al published August 1992 in International Journal of Geriatric Psychiatry

The assessment of changes in cognitive functioning in the elderly: age- and education-specific reliable change indices for the SIDAM.

scientific article published on 9 March 2012

The assessment of changes in cognitive functioning: age-, education-, and gender-specific reliable change indices for older adults tested on the CERAD-NP battery: results of the German Study on Ageing, Cognition, and Dementia in Primary Care Patient

scientific article published in January 2012

The clock drawing test and questionable dementia: reliability and validity

scientific article published in November 2002

The costs of dementia from the societal perspective: is care provided in the community really cheaper than nursing home care?

scientific article

The impact of social engagement on health-related quality of life and depressive symptoms in old age - evidence from a multicenter prospective cohort study in Germany

scientific article

The role of spousal loss in the development of depressive symptoms in the elderly - implications for diagnostic systems

scientific article published on 11 March 2014

Unmet Care Needs in the Oldest Old Primary Care Patients with Cognitive Disorders: Results of the AgeCoDe and AgeQualiDe Study

scientific article

Vitamin D deficiency, cognitive impairment and dementia: a systematic review and meta-analysis

scientific article

Which factors influence cognitive decline in older adults suffering from dementing disorders?

scientific article published in November 2002

Which types of mental work demands may be associated with reduced risk of dementia?

scientific article published on 28 September 2016

Women Outperform Men in Verbal Episodic Memory Even in Oldest-Old Age: 13-Year Longitudinal Results of the AgeCoDe/AgeQualiDe Study

scientific article published on 01 January 2019

[Does an Increase in Depressive Symptoms Lead to an Increase in Functional Impairment or vice versa? Results of the AgeCoDe and AgeQualiDe Study]

scientific article published on 17 January 2020

List of works by Horst Bickel

A comparison of GP and GDS diagnosis of depression in late life among multimorbid patients - results of the MultiCare study

AD dementia risk in late MCI, in early MCI, and in subjective memory impairment

APOE e4-allele and mental work demands on cognitive decline in old age: Results from the German Study on Ageing, Cognition, and Dementia in Primary Care Patients (AgeCoDe)

Advance directives and power of attorney for health care in the oldest-old - results of the AgeQualiDe study

Age-correction of test scores reduces the validity of mild cognitive impairment in predicting progression to dementia

Age-related predictors of institutionalization: results of the German study on ageing, cognition and dementia in primary care patients (AgeCoDe).

Agreement between self-reported and general practitioner-reported chronic conditions among multimorbid patients in primary care - results of the MultiCare Cohort Study

Anticholinergic drug use and risk for dementia: target for dementia prevention

Apart from nihilism and stigma: what influences general practitioners' accuracy in identifying incident dementia?

Association between multimorbidity patterns and chronic pain in elderly primary care patients: a cross-sectional observational study

Association of the Alzheimer's disease clusterin risk allele with plasma clusterin concentration.

Associations between Dementia Outcomes and Depressive Symptoms, Leisure Activities, and Social Support

Associations between dementia and head circumference as a measure of brain reserve--results from the Bavarian School sisters study

At-risk alcohol drinking in primary care patients aged 75 years and older

Carotid intima-media thickness progression and risk of vascular events in people with diabetes: results from the PROG-IMT collaboration

Cerebrospinal fluid biomarkers for Alzheimer's disease: the role of apolipoprotein E genotype, age, and sex.

Chronic kidney disease is associated with incident cognitive impairment in the elderly: the INVADE study

Cognitive performance before and after the onset of subjective cognitive decline in old age.

Cognitive reserve, homocysteine, and cognition in the Bavarian School Sisters Study

Combined effects of hemoglobin A1c and C-reactive protein on the progression of subclinical carotid atherosclerosis: the INVADE study

Complex coevolution of depression and health-related quality of life in old age.

Converging genetic and functional brain imaging evidence links neuronal excitability to working memory, psychiatric disease, and brain activity

Correction: Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration

Current alcohol consumption and its relationship to incident dementia: results from a 3-year follow-up study among primary care attenders aged 75 years and older

Dementia friendly care services in general hospitals : Representative results of the general hospital study (GHoSt)

Depression, non-fatal stroke and all-cause mortality in old age: a prospective cohort study of primary care patients

Depressive mood mediates the influence of social support on health-related quality of life in elderly, multimorbid patients

Depressive symptoms and the risk of ischemic stroke in the elderly--influence of age and sex.

Depressive symptoms as predictor of dementia versus continuous cognitive decline: a 3-year prospective study

Determinants of incident dementia in different old age groups: results of the prospective AgeCoDe/AgeQualiDe study

Differential Risk of Incident Alzheimer's Disease Dementia in Stable Versus Unstable Patterns of Subjective Cognitive Decline

Disentangling the complex relation of disability and depressive symptoms in old age - findings of a multicenter prospective cohort study in Germany

Driving status and health-related quality of life among the oldest old: a population-based examination using data from the AgeCoDe-AgeQualiDe prospective cohort study

Education, occupation, and dementia: the Bavarian school sisters study

Effect of Visual Impairment on Physical and Cognitive Function in Old Age: Findings of a Population-Based Prospective Cohort Study in Germany

Effect of cardiovascular and metabolic disease on cognitive test performance and cognitive change in older adults

Effects of multiple chronic conditions on health care costs: an analysis based on an advanced tree-based regression model

Elevated HbA1c is associated with increased risk of incident dementia in primary care patients

Gender differences in the effect of social support on health-related quality of life: results of a population-based prospective cohort study in old age in Germany

Gene polymorphisms in prodynorphin (PDYN) are associated with episodic memory in the elderly

General practitioners' judgment of their elderly patients' cognitive status

Genetic Analysis of Association Between Calcium Signaling and Hippocampal Activation, Memory Performance in the Young and Old, and Risk for Sporadic Alzheimer Disease

High risk of cognitive and functional decline after postoperative delirium. A three-year prospective study

High-sensitivity C-reactive protein at different stages of atherosclerosis: results of the INVADE study

How does social support affect functional impairment in late life? Findings of a multicenter prospective cohort study in Germany

Impact of depression on health care utilization and costs among multimorbid patients--from the MultiCare Cohort Study

Impact of falls on depressive symptoms among the oldest old: Results from the AgeQualiDe study

Implementation of chronic illness care in German primary care practices--how do multimorbid older patients view routine care? A cross-sectional study using multilevel hierarchical modeling

In Reply

Incidence and predictors of depression in non-demented primary care attenders aged 75 years and older: results from a 3-year follow-up study

Incidence and risk factors of delirium after hip surgery

Incident Subjective Cognitive Decline Does Not Predict Mortality in the Elderly--Results from the Longitudinal German Study on Ageing, Cognition, and Dementia (AgeCoDe).

Individual progression of carotid intima media thickness as a surrogate for vascular risk (PROG-IMT): Rationale and design of a meta-analysis project

Inflammatory markers and extent and progression of early atherosclerosis: Meta-analysis of individual-participant-data from 20 prospective studies of the PROG-IMT collaboration

Is function in instrumental activities of daily living a useful feature in predicting Alzheimer's disease dementia in subjective cognitive decline?

Is the Short Form of the Mini-Mental State Examination (MMSE) a better screening instrument for dementia in older primary care patients than the original MMSE? Results of the German study on ageing, cognition, and dementia in primary care patients (

Late-Life Depressive Symptoms and Lifetime History of Major Depression: Cognitive Deficits are Largely Due to Incipient Dementia rather than Depression

Longitudinal Predictors of Institutionalization in Old Age.

Longitudinal predictors of informal and formal caregiving time in community-dwelling dementia patients

Malperformance in verbal fluency and delayed recall as cognitive risk factors for impairment in instrumental activities of daily living.

Mental health in the aged: prevalence, covariates and related neuroendocrine, cardiovascular and inflammatory factors of successful aging

Metabolic and endocrine factors in mild cognitive impairment

Mild cognitive impairment and quality of life in the oldest old: a closer look

Mild cognitive impairment in general practice: age-specific prevalence and correlate results from the German study on ageing, cognition and dementia in primary care patients (AgeCoDe)

Mild cognitive impairment: making headway by stepping backwards.

Mortality in Incident Cognitive Impairment: Results of the Prospective AgeCoDe Study

Motivational reserve: Motivation-related occupational abilities and risk of mild cognitive impairment and Alzheimer disease ⬇️

Normative values for carotid intima media thickness and its progression: Are they transferrable outside of their cohort of origin?

Obesity and associated lifestyle in a large sample of multi-morbid German primary care attendees

Patterns of subjective memory impairment in the elderly: association with memory performance.

Physical activity and incident cognitive impairment in elderly persons: the INVADE study

Potentially inappropriate medication: Association between the use of antidepressant drugs and the subsequent risk for dementia

Predicting dementia in primary care patients with a cardiovascular health metric: a prospective population-based study

Prediction of dementia by subjective memory impairment: effects of severity and temporal association with cognitive impairment.

Prediction of dementia in primary care patients.

Predictive value for cardiovascular events of common carotid intima media thickness and its rate of change in individuals at high cardiovascular risk - Results from the PROG-IMT collaboration

Predictors of costs in dementia in a longitudinal perspective

Predictors of institutionalisation in incident dementia--results of the German Study on Ageing, Cognition and Dementia in Primary Care Patients (AgeCoDe study).

Prevalence and determinants of driving habits in the oldest old: Results of the multicenter prospective AgeCoDe-AgeQualiDe study