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List of works by John Hwa Lee

A live attenuated Salmonella Enteritidis secreting detoxified heat labile toxin enhances mucosal immunity and confers protection against wild-type challenge in chickens.

scientific article published on 04 June 2016

A live attenuated mutant of Salmonella Montevideo triggers IL-6, IFN-γ and IL-12 cytokines that co-related with humoral and cellular immune responses required for reduction of challenge bacterial load in experimental chickens

scientific article published on 6 November 2016

An attenuated Salmonella vaccine secreting Lawsonia intracellularis immunogenic antigens confers dual protection against porcine proliferative enteropathy and salmonellosis in a murine model

scientific article published on 01 May 2019

Brucella lipopolysaccharide reinforced Salmonella delivering Brucella immunogens protects mice against virulent challenge

scientific article published on 17 May 2017

Corrigendum: Pathogenic traits of Salmonella Montevideo in experimental infections in vivo and in vitro

scientific article

Deletion of the lon gene augments expression of Salmonella Pathogenicity Island (SPI)-1 and metal ion uptake genes leading to the accumulation of bactericidal hydroxyl radicals and host pro-inflammatory cytokine-mediated rapid intracellular clearanc

scientific article published on 21 June 2020

Development and trial of vaccines against Brucella

scientific article

Effect of immunization routes and protective efficacy of Brucella antigens delivered via Salmonella vector vaccine

scientific article published on 25 January 2018

Engineering of a rough auxotrophic mutant Salmonella Typhimurium for effective delivery.

scientific article published on 22 May 2018

Enhancement of host infectivity, immunity, and protective efficacy by addition of sodium bicarbonate antacid to oral vaccine formulation of live attenuated Salmonella secreting Brucella antigens

scientific article published on 06 November 2019

Immunization of chickens with Salmonella gallinarium ghosts expressing Salmonella Enteritidis NFliC-FimAC and CD40LC fusion antigen enhances cell-mediated immune responses and protects against wild-type challenges with both species

scientific article published in 2022

Immunization of guinea pigs with Salmonella delivered anti-Brucella formulation reduces organs bacterial load and mitigates histopathological consequences of Brucella abortus 544 challenge

scientific article published on 23 November 2017

Immunization with Salmonella Enteritidis secreting mucosal adjuvant labile toxin confers protection against wild type challenge via augmentation of CD3+CD4+ T-cell proliferation and enhancement of IFN-γ, IL-6 and IL-10 expressions in chicken

scientific article published on 4 January 2017

Immuno-profiles of BALB/c mice inoculated with Salmonella vector delivering B-cell mitogen hydroxyproline epimerase

scientific article published on 9 February 2018

Intranasally administered anti-Brucella subunit vaccine formulation induces protective immune responses against nasal Brucella challenge

scientific article published on 23 November 2018

Intranasally administered protein coated chitosan nanoparticles encapsulating influenza H9N2 HA2 and M2e mRNA molecules elicit protective immunity against avian influenza viruses in chickens

scientific article published on 06 March 2020

Live vaccine consisting of attenuated Salmonella secreting and delivering Brucella ribosomal protein L7/L12 induces humoral and cellular immune responses and protects mice against virulent Brucella abortus 544 challenge

scientific article published on 23 January 2020

O-antigen-deficient, live, attenuated Salmonella typhimurium confers efficient uptake, reduced cytotoxicity, and rapid clearance in chicken macrophages and lymphoid organs and induces significantly high protective immune responses that protect chick

scientific article published on 26 May 2020

Oral immunization with an attenuated Salmonella Gallinarum encoding the H9N2 hemagglutinin and M2 ectodomain induces protective immune responses against H9N2 infection in chickens

scientific article published on 02 June 2020

Parenteral immunization of Salmonella Typhimurium ghosts with surface-displayed Escherichia coli flagellin enhancesTLR-5 mediated activation of immune responses that protect the chicken against Salmonella infection

scientific article published on 18 May 2020

Partial protection induced by Salmonella based Brucella vaccine candidate in pregnant guinea pigs

scientific article published on 17 January 2019

Pathogenic traits of Salmonella Montevideo in experimental infections in vivo and in vitro

scientific article published on 07 April 2017

Protective efficacy and immune responses by homologous prime-booster immunizations of a novel inactivated Salmonella Gallinarum vaccine candidate

scientific article published on 29 July 2016

Safety implication of Salmonella based Brucella vaccine candidate in mice and in vitro human cell culture.

scientific article

Salmonella Enteritidis ghost vaccine carrying the hemagglutinin globular head (HA1) domain from H1N1 virus protects against salmonellosis and influenza in chickens

scientific article published on 08 May 2020

Salmonella enterica serovar Enteritidis ghosts displaying a surface FliC adjuvant elicit a robust immune response and effective protection against virulent challenge

scientific article published on 02 March 2020