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List of works by Henk M W Verheul

11C-sorafenib and 15O-H2O PET for early evaluation of sorafenib therapy

scientific article published on 30 October 2020

89Zr-cetuximab PET imaging in patients with advanced colorectal cancer.

scientific article

A specific microRNA profile as predictive biomarker for systemic treatment in patients with metastatic colorectal cancer

scientific article published on 30 August 2020

Acquired tumor cell resistance to sunitinib causes resistance in a HT-29 human colon cancer xenograft mouse model without affecting sunitinib biodistribution or the tumor microvasculature

scientific article

Activated iNKT cells promote Vγ9Vδ2-T cell anti-tumor effector functions through the production of TNF-α.

scientific article published on 4 November 2011

Analysis of AKT and ERK1/2 protein kinases in extracellular vesicles isolated from blood of patients with cancer.

scientific article published on 8 December 2014

Antiangiogenic tyrosine kinase inhibition related gastrointestinal perforations: a case report and literature review ⬇️

scientific article published on December 29, 2010

Blood platelets contain tumor-derived RNA biomarkers

scientific article

CD1d-restricted antigen presentation by Vγ9Vδ2-T cells requires trogocytosis

scientific article

CD44 Isoform Status Predicts Response to Treatment with Anti-CD44 Antibody in Cancer Patients

scientific article

Combination of a six microRNA expression profile with four clinicopathological factors for response prediction of systemic treatment in patients with advanced colorectal cancer

scientific article published in PLoS ONE

Combinatorial Immunotherapies for Metastatic Colorectal Cancer

scientific article published on 12 July 2020

Combining radiotherapy with sunitinib: lessons (to be) learned

scientific article

Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy

scientific article published in Nature Communications

Dietician-delivered intensive nutritional support is associated with a decrease in severe postoperative complications after surgery in patients with esophageal cancer ⬇️

scientific article published on December 13, 2012

Dried blood spot analysis for therapeutic drug monitoring of pazopanib

scientific article

Early 18F-FDG PET/CT Evaluation Shows Heterogeneous Metabolic Responses to Anti-EGFR Therapy in Patients with Metastatic Colorectal Cancer.

scientific article

Effect of Itraconazole and Rifampin on the Pharmacokinetics of Olaparib in Patients With Advanced Solid Tumors: Results of Two Phase I Open-label Studies

scientific article published on 10 October 2016

Epithelial Transfer of the Tyrosine Kinase Inhibitors Erlotinib, Gefitinib, Afatinib, Crizotinib, Sorafenib, Sunitinib, and Dasatinib: Implications for Clinical Resistance

scientific article published on 10 November 2020

Exploration of the platelet proteome in patients with early-stage cancer.

scientific article published on 9 February 2018

Feasibility of label-free phosphoproteomics and application to base-line signaling of colorectal cancer cell lines.

scientific article published on April 2015

INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases

scientific article published on 12 April 2019

INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases

scientific article published on 24 May 2019

Implementing Reverse Phase Protein Array Profiling as a Sensitive Method for the Early Pre-Clinical Detection of Off-Target Toxicities Associated with Sunitinib Malate

scientific article published on 19 March 2019

Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance.

scientific article published on 6 October 2011

Neo-adjuvant chemotherapy followed by surgery versus surgery alone in high-risk patients with resectable colorectal liver metastases: the CHARISMA randomized multicenter clinical trial

scientific article

Non-metastasized oesophageal cancer

scientific article published on 01 January 2010

Novel strategies towards the use of anti-angiogenic agents in breast cancer ⬇️

scientific article published on March 30, 2013

Olanzapine Versus Haloperidol for Treatment of Delirium in Patients with Advanced Cancer: A Phase III Randomized Clinical Trial

scientific article published on 08 December 2019

Optimal treatment scheduling of ionizing radiation and sunitinib improves the antitumor activity and allows dose reduction

scientific article

PET/CT-derived whole-body and bone marrow dosimetry of 89Zr-cetuximab

scientific article published on 22 January 2015

Phase I evaluation of telatinib, a VEGF receptor tyrosine kinase inhibitor, in combination with bevacizumab in subjects with advanced solid tumors ⬇️

scientific article published on March 4, 2011

Phosphotyrosine-based phosphoproteomics for target identification and drug response prediction in AML cell lines

scientific article published on 26 February 2020

Platelets: an unexploited data source in biomarker research

scientific article

Proteomic Analysis of miR-195 and miR-497 Replacement Reveals Potential Candidates that Increase Sensitivity to Oxaliplatin in MSI/P53wt Colorectal Cancer Cells

scientific article published on 19 September 2019

RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics

scientific article

Rapid decrease in delivery of chemotherapy to tumors after anti-VEGF therapy: implications for scheduling of anti-angiogenic drugs

scientific article published in January 2012

Reversible posterior leukoencephalopathy syndrome during sunitinib therapy for metastatic renal cell carcinoma ⬇️

scientific article published on March 16, 2012

Screening and Stepped Care Targeting Psychological Distress in Patients With Metastatic Colorectal Cancer: The TES Cluster Randomized Trial

scientific article published on 01 August 2019

Screening and treatment of psychological distress in patients with metastatic colorectal cancer: study protocol of the TES trial

scientific article published on 17 April 2015

Smartphone measurements of physical activity and fitness are associated with early trial discontinuation of patients in (hemato)oncology phase I/II clinical trials

scientific article published on 24 November 2020

Subnuclear proteomics in colorectal cancer: identification of proteins enriched in the nuclear matrix fraction and regulation in adenoma to carcinoma progression.

scientific article published on 20 January 2010

Targeting JNK-interacting protein 1 (JIP1) sensitises osteosarcoma to doxorubicin ⬇️

scientific article published on October 1, 2012

The Current Status of Immune Checkpoint Inhibitors in Neuro-Oncology: A Systematic Review

scientific article published on 04 March 2020

The Neo-Open Reading Frame Peptides That Comprise the Tumor Framome Are a Rich Source of Neoantigens for Cancer Immunotherapy

scientific article published in 2024

The future of colorectal cancer: implications of screening ⬇️

scientific article published on June 8, 2013

Therapeutic drug monitoring to individualize the dosing of pazopanib: a pharmacokinetic feasibility study

scientific article published on 01 June 2015

Time dependent effect of cold ischemia on the phosphoproteome and protein kinase activity in fresh-frozen colorectal cancer tissue obtained from patients

scientific article published on 18 February 2021

Weight Loss of 5% or More Predicts Loss of Fat-Free Mass During Palliative Chemotherapy in Patients With Advanced Cancer: A Pilot Study ⬇️

scientific article published on June 14, 2012

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