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List of works by Piotr Sicinski

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers

scientific article

A mitotic CDK5-PP4 phospho-signaling cascade primes 53BP1 for DNA repair in G1

scientific article published on 18 September 2019

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells

scientific article

Aberrant cell cycle progression and endoreplication in regenerating livers of mice that lack a single E-type cyclin

scientific article published on 13 May 2009

Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy

scientific article published on 24 August 2020

Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer

scientific article published on 11 May 2020

Canonical and atypical E2Fs regulate the mammalian endocycle

scientific journal article

Cell cycle progression without cyclin D-CDK4 and cyclin D-CDK6 complexes

scientific article

Cell cycle proteins as promising targets in cancer therapy

scientific article published on January 2017

Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus

scientific article

Cerebellar cortical lamination and foliation require cyclin A2

scientific article (publication date: 15 January 2014)

Concurrent deletion of cyclin E1 and cyclin-dependent kinase 2 in hepatocytes inhibits DNA replication and liver regeneration in mice

scientific article

Critical role for cyclin D2 in BCR/ABL-induced proliferation of hematopoietic cells

scientific journal article

Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells

scientific journal article

Cyclin A2 promotes DNA repair in the brain during both development and aging.

scientific article published on 13 July 2016

Cyclin C is a haploinsufficient tumour suppressor

scientific article

Cyclin D activates the Rb tumor suppressor by mono-phosphorylation

scientific article

Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells.

scientific article published on 05 May 2009

Cyclin D1 represses gluconeogenesis via inhibition of the transcriptional coactivator PGC1α

scientific article

Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression

scientific article

Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis

scientific article

Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number

scientific article

Cyclin E Constrains Cdk5 Activity to Regulate Synaptic Plasticity and Memory Formation ⬇️

scientific article published on September 22, 2011

Cyclin E ablation in the mouse

scientific journal article

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

scientific article

Development of mice expressing a single D-type cyclin.

scientific article published on December 2002

E-type cyclins modulate telomere integrity in mammalian male meiosis

scientific article published on 28 December 2015

FoxM1 is a downstream target and marker of HER2 overexpression in breast cancer

scientific article

Genetic replacement of cyclin D1 function in mouse development by cyclin D2.

scientific article

Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition

scientific article published on 17 June 2020

MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis

scientific article published on 24 August 2016

Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases

scientific article published on April 2016

Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases

scientific article

Overcoming Therapeutic Resistance in HER2-Positive Breast Cancers with CDK4/6 Inhibitors

scientific article published on March 2016

PP2A-mediated regulation of Ras signaling in G2 is essential for stable quiescence and normal G1 length

scientific article

Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ

scientific article published on 13 September 2019

Postsynaptic GABAB receptor activity regulates excitatory neuronal architecture and spatial memory

scientific article published on January 2014

Proteomic Identification of a Direct Role for Cyclin D1 in DNA Damage Repair ⬇️

scientific article published on August 22, 2012

Proteomic Landscape of Tissue-Specific Cyclin E Functions in Vivo.

scientific article

Requirement for CDK4 kinase function in breast cancer

scientific journal article

Requirement for cyclin D3 in germinal center formation and function.

scientific article

Requirement for cyclin D3 in lymphocyte development and T cell leukemias

scientific journal article

Targeting cyclins and cyclin-dependent kinases in cancer: lessons from mice, hopes for therapeutic applications in human

scientific article published on 15 September 2006

The E4F protein is required for mitotic progression during embryonic cell cycles

scientific journal article

The Kinase-Independent, Second Life of CDK6 in Transcription ⬇️

scientific article published on August 12, 2013

The Requirement for Cyclin D Function in Tumor Maintenance ⬇️

scientific article published on October 16, 2012

The cell cycle in stem cell proliferation, pluripotency and differentiation

scientific article published on 02 September 2019

The cyclin D1-CDK4 oncogenic interactome enables identification of potential novel oncogenes and clinical prognosis

scientific article

The retinoblastoma protein regulates pericentric heterochromatin

scientific article

p600 Plays Essential Roles in Fetal Development ⬇️

scientific article published on June 18, 2013

β-Selection-Induced Proliferation Is Required for αβ T Cell Differentiation ⬇️

scientific article published on November 16, 2012

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