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List of works by Timo D. Müller

'Fat mass and obesity associated' gene (FTO): no significant association of variant rs9939609 with weight loss in a lifestyle intervention and lipid metabolism markers in German obese children and adolescents

scientific article

(Patho)Physiology of Glycosylphosphatidylinositol-Anchored Proteins I: Localization at Plasma Membranes and Extracellular Compartments

scientific article published in 2023

A New FGF21 Analog for the Treatment of Fatty Liver Disease

scientific article published on 01 August 2020

A collective diabetes cross in combination with a computational framework to dissect the genetics of human obesity and Type 2 diabetes

scientific article published on 01 September 2018

A guide to analysis of mouse energy metabolism

scientific article published on 28 December 2011

A macrophage NBR1-MEKK3 complex triggers JNK-mediated adipose tissue inflammation in obesity

scientific article

A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents

scientific article published on 8 December 2014

Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis

scientific article published on 21 December 2020

Acylation type determines ghrelin's effects on energy homeostasis in rodents

scientific article

Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition.

scientific article published on 20 September 2016

Adipocyte p62/SQSTM1 Suppresses Tumorigenesis through Opposite Regulations of Metabolism in Adipose Tissue and Tumor

scientific article published in April 2018

Age-dependent membrane release and degradation of full-length glycosylphosphatidylinositol-anchored proteins in rats

scientific article published on 03 July 2020

Allan-Herndon-Dudley-Syndrome: Considerations about the Brain Phenotype with Implications for Treatment Strategies

scientific article published on 02 April 2020

Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis

scientific article published on 17 April 2017

An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation

article published in 2018

Animal models of obesity and diabetes mellitus

scientific article published on 19 January 2018

Author Correction: Targeted pharmacological therapy restores β-cell function for diabetes remission

correction of a scholarly article

CB1 Receptor-Dependent and Independent Induction of Lipolysis in Primary Rat Adipocytes by the Inverse Agonist Rimonabant (SR141716A)

scientific article published on 18 February 2020

CNS-targeting pharmacological interventions for the metabolic syndrome

scientific article published on 05 August 2019

Calcineurin Links Mitochondrial Elongation with Energy Metabolism

scientific article

Caloric restriction chronically impairs metabolic programming in mice

scientific article

Chemical Hybridization of Glucagon and Thyroid Hormone Optimizes Therapeutic Impact for Metabolic Disease

scientific article published on 6 October 2016

Circulating HDL levels control hypothalamic astrogliosis via apoA-I

scientific article published in 2018

Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes

scientific article published in Nature Communications

Correlation guided Network Integration (CoNI) reveals novel genes affecting hepatic metabolism

scientific article published on 13 July 2021

Corrigendum to "Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice" [Molecular Metabolism 23 (2019) 75-81]

scientific article published on 01 December 2019

Coupled with uncouplers: the curious case of lifespan

scientific article published on 10 February 2009

Current and Emerging Treatment Options in Diabetes Care

scientific article published on 23 April 2015

Current and emerging therapies for managing hyperphagia and obesity in Prader-Willi syndrome: A narrative review

scientific article published on 30 December 2019

Determination of thyroid hormones in mouse tissues by isotope-dilution microflow liquid chromatography-mass spectrometry method

scientific article published on 26 August 2016

Development and validation of an LC-MS/MS methodology for the quantification of thyroid hormones in dko MCT8/OATP1C1 mouse brain

scientific article published in 2022

Dual melanocortin-4 receptor and GLP-1 receptor agonism amplifies metabolic benefits in diet-induced obese mice

scientific article published on 4 February 2015

Dual specificity phosphatase 6 deficiency is associated with impaired systemic glucose tolerance and reversible weight retardation in mice

scientific article

Duodenal nutrient exclusion improves metabolic syndrome and stimulates villus hyperplasia

scientific article published on 09 October 2013

Effects of Placebo Interventions on Subjective and Objective Markers of Appetite-A Randomized Controlled Trial

Emerging Poly-Agonists for Obesity and Type 2 Diabetes

scientific article published in October 2017

Emerging function of fat mass and obesity-associated protein (fto)

scientific article

Emerging hormonal-based combination pharmacotherapies for the treatment of metabolic diseases

scientific article published on 01 February 2019

Emerging opportunities for the treatment of metabolic diseases: Glucagon-like peptide-1 based multi-agonists

scientific article published on 04 July 2015

Erratum. Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition. Diabetes 2017;66:272-286.

scientific article published on 16 November 2017

Exercise protects against high-fat diet-induced hypothalamic inflammation

scientific article

FGF21 is not required for glucose homeostasis, ketosis or tumour suppression associated with ketogenic diets in mice

scientific article published on 23 June 2015

Fat mass and obesity-associated gene (FTO) in eating disorders: evidence for association of the rs9939609 obesity risk allele with bulimia nervosa and anorexia nervosa

scientific article published on 27 June 2012

Fibroblast activation protein (FAP) as a novel metabolic target

scientific article published on 16 July 2016

Fibroblast growth factor 21 mediates specific glucagon actions

scientific article published on 10 January 2013

G-Protein Coupled Receptor 83 (GPR83) Signaling Determined by Constitutive and Zinc(II)-Induced Activity ⬇️

scientific article published on January 15, 2013

GLP-1/glucagon coagonism restores leptin responsiveness in obese mice chronically maintained on an obesogenic diet

scientific article published on 30 December 2013

GLP-1/glucagon receptor co-agonism for treatment of obesity.

scientific article

GLP-1R agonism enhances adjustable gastric banding in diet-induced obese rats

scientific article published on 17 June 2013

GLP-1R responsiveness predicts individual gastric bypass efficacy on glucose tolerance in rats

scientific article

Genetic variation of the ghrelin activator gene ghrelin O-acyltransferase (GOAT) is associated with anorexia nervosa

scientific article

Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants

scientific article

Genome-Wide Association Study Reveals First Locus for Anorexia Nervosa and Metabolic Correlations

scholarly article

Ghrelin - a key pleiotropic hormone-regulating systemic energy metabolism

scientific article published on 25 April 2013

Ghrelin and LEAP-2: Rivals in Energy Metabolism

scholarly article by Omar Al-Massadi et al published August 2018 in Trends in Pharmacological Sciences

Ghrelin and its potential in the treatment of eating/wasting disorders and cachexia

scientific article

Ghrelin in the control of energy, lipid, and glucose metabolism

scientific article published on 01 January 2012

Ghrelin regulation of glucose metabolism

scientific article published in February 2018

Glucagon Regulation of Energy Expenditure ⬇️

scientific article published on 30 October 2019

Gut Peptide Agonism in the Treatment of Obesity and Diabetes

scientific article published on 18 December 2019

Gut hormone polyagonists for the treatment of type 2 diabetes

scientific article published in February 2018

Gut-Brain Cross-Talk in Metabolic Control

scientific article

Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity

scientific article published on 14 October 2019

Hypothalamic leptin action is mediated by histone deacetylase 5.

scientific article

Identification of GPR83 as the receptor for the neuroendocrine peptide PEN.

scientific article published on 26 April 2016

Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein

article by Maximilian Bielohuby et al published January 2011 in American Journal of Physiology - Endocrinology and Metabolism

Influence of acute exposure to high altitude on basal and postprandial plasma levels of gastroenteropancreatic peptides

scientific article

Insights into incretin-based therapies for treatment of diabetic dyslipidemia

scientific article published on 30 May 2020

Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa

scientific article

Leptin-mediated neuroendocrine alterations in anorexia nervosa: somatic and behavioral implications

scientific article published on January 2009

Metabolic Precision Medicines: Curing POMC Deficiency

scientific article published on 20 July 2016

Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs

scientific article published on 28 June 2018

Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity

scientific article published on 19 September 2017

Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice

scientific article

Mutation screen and association studies for the fatty acid amide hydrolase (FAAH) gene and early onset and adult obesity

scientific article

No evidence for an involvement of variants in the cannabinoid receptor gene (CNR1) in obesity in German children and adolescents

article

Non-replication of an association of CTNNBL1 polymorphisms and obesity in a population of Central European ancestry

scientific article published on 19 February 2009

Obesity in MENX Rats Is Accompanied by High Circulating Levels of Ghrelin and Improved Insulin Sensitivity

scientific article

Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity

scientific article published on 06 March 2020

Pirt deficiency has subtle female-specific effects on energy and glucose metabolism in mice

scientific article published on 07 March 2019

Plasma proteome profiles treatment efficacy of incretin dual agonism in diet-induced obese female and male mice

scientific article published on 01 October 2020

Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease

scientific article published on 01 March 2019

Play down protein to play up metabolism?

scientific article published on 18 August 2014

Publisher Correction: Coordinated targeting of cold and nicotinic receptors synergistically improves obesity and type 2 diabetes

scientific article published in Nature Communications

Reappraisal of GIP Pharmacology for Metabolic Diseases

scientific article published on 30 March 2016

Relationship status update for PTP1B and LepR: It׳s complicated.

scientific article published on 7 February 2014

Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21

scientific article published on 04 May 2012

Review of novel aspects of the regulation of ghrelin secretion

scientific article published on January 2014

Revisiting the Pharmacological Value of Glucagon: An Editorial for the Special Issue "The Biology and Pharmacology of Glucagon"

scientific article published on 08 January 2020

Role of adipose and hepatic atypical protein kinase C lambda (PKCλ) in the development of obesity and glucose intolerance

scientific article published on October 2012

Targeted estrogen delivery reverses the metabolic syndrome

scientific article

Targeted pharmacological therapy restores β-cell function for diabetes remission

scientific article published on 20 February 2020

Teaching an old dog new tricks: metformin induces body-weight loss via GDF15

scientific article published on 01 December 2019

The 1D1 of burning calories.

scientific article published on 23 October 2008

The Effect of SH2B1 Variants on Expression of Leptin- and Insulin-Induced Pathways in Murine Hypothalamus.

scientific article published on 10 April 2018

The GOAT-ghrelin system is not essential for hypoglycemia prevention during prolonged calorie restriction

scientific article

The Pentapeptide RM-131 Promotes Food Intake and Adiposity in Wildtype Mice but Not in Mice Lacking the Ghrelin Receptor

scientific article published on January 2014

The extracellular N-terminal domain of G-protein coupled receptor 83 regulates signaling properties and is an intramolecular inverse agonist

scientific article published on 16 December 2014

The glucocorticoid receptor in brown adipocytes is dispensable for control of energy homeostasis

scientific article published on 26 September 2019

The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms

scientific article

The potential of glucagon-like peptide 1 to reverse high-fat, high-sugar diet-related metabolic damage

scientific article published on 28 April 2014

The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation

scientific article published on 08 May 2020

Therapeutic Potential of Targeting the Ghrelin Pathway

scientific article

Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups

scientific journal article

Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity

scientific article published on 11 August 2020

Unimolecular Polypharmacy for Treatment of Diabetes and Obesity

scientific article

Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans.

scientific article published in October 2013

Upregulated phospholipase D activity toward glycosylphosphatidylinositol-anchored proteins in micelle-like serum complexes in metabolically deranged rats and humans

scientific article published on 21 January 2020

p62 links β-adrenergic input to mitochondrial function and thermogenesis

scientific article published on 21 December 2012

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