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List of works by Hiroshi Mitsumoto

A novel muscle cramp scale (MCS) in amyotrophic lateral sclerosis (ALS)

scientific article published on 22 April 2019

A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS.

scientific article

A pathogenic peripherin gene mutation in a patient with amyotrophic lateral sclerosis

scientific article

A post hoc analysis of subgroup outcomes and creatinine in the phase III clinical trial (EMPOWER) of dexpramipexole in ALS

article

A proposal for new diagnostic criteria for ALS

scientific article published on 19 April 2020

A prospective cohort study of neuropsychological test performance in ALS.

scientific article published in May 2010

A robotic neck brace to characterize head-neck motion and muscle electromyography in subjects with amyotrophic lateral sclerosis

scientific article published on 07 August 2019

A screening assessment of cognitive impairment in patients with ALS.

scientific article published on 30 July 2007

ALS Multicenter Cohort Study of Oxidative Stress (ALS COSMOS): study methodology, recruitment, and baseline demographic and disease characteristics

scientific article

ALS Untangled No. 20: the Deanna protocol

scientific article published on 02 May 2013

ALS and physician-assisted suicide

scientific article published on 8 July 2016

Amino acids for amyotrophic lateral sclerosis / motor neuron disease

scientific article

Amino acids for amyotrophic lateral sclerosis / motor neuron disease

scientific article (published 2003-10-20)

Amyotrophic lateral sclerosis

scientific article published on 03 September 2003

Amyotrophic lateral sclerosis and neurosarcoidosis: a case report

scientific article

Amyotrophic lateral sclerosis and primary lateral sclerosis: evidence-based diagnostic evaluation of the upper motor neuron

scientific article

Amyotrophic lateral sclerosis and spinocerebellar ataxia type 2 in a family with full CAG repeat expansions of ATXN2.

scientific article

Amyotrophic lateral sclerosis with ragged-red fibers

scientific article published on March 2008

Amyotrophic lateral sclerosis: a consensus viewpoint on designing and implementing a clinical trial

scientific article published on June 2004

Amyotrophic lateral sclerosis: a long preclinical period?

scientific article published on 19 March 2014

Amyotrophic lateral sclerosis: an emerging era of collaborative gene discovery

scientific article

Amyotrophic lateral sclerosis: objective upper motor neuron markers

scientific article

An observational study of cognitive impairment in amyotrophic lateral sclerosis

scientific article published in March 2006

Association Between Dietary Intake and Function in Amyotrophic Lateral Sclerosis

scientific article

Biochemical markers: Con

Bioenergetic markers in skin fibroblasts of sporadic amyotrophic lateral sclerosis and progressive lateral sclerosis patients

scientific article

Caregiver assessment: summary

scientific article published in January 2002

Chapter 20 Symptomatic therapy and palliative aspects of clinical care

scientific article published on 01 January 2007

Clinical care of patients with amyotrophic lateral sclerosis

scientific article published on October 2007

Clinical evolution of pure upper motor neuron disease/dysfunction (PUMMD)

scientific article

Clinical perspective on oxidative stress in sporadic amyotrophic lateral sclerosis ⬇️

scientific article published on June 21, 2013

Clinical trials in amyotrophic lateral sclerosis: why so many negative trials and how can trials be improved?

scientific article

Cognitive impairment, behavioral impairment, depression, and wish to die in an ALS cohort

scientific article published on 5 August 2016

Cognitive-behavioral screening reveals prevalent impairment in a large multicenter ALS cohort.

scientific article

Controversies and priorities in amyotrophic lateral sclerosis

scientific article

Corrigendum to "Longitudinal Screening Detects Cognitive Stability and Behavioral Deterioration in ALS Patients"

scientific article published on 04 December 2019

Deciphering amyotrophic lateral sclerosis: What phenotype, neuropathology and genetics are telling us about pathogenesis ⬇️

scientific article published on May 1, 2013

Depression and wish to die in a multicenter cohort of ALS patients

scientific article published on 8 December 2014

Dexpramipexole versus placebo for patients with amyotrophic lateral sclerosis (EMPOWER): a randomised, double-blind, phase 3 trial

scientific article published on 23 September 2013

Differential susceptibility of the ocular motor system to disease.

scientific article

Drug therapy in amyotrophic lateral sclerosis.

scientific article

Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial.

scientific article

Electrodiagnostic criteria for diagnosis of ALS.

scientific article published on 27 December 2007

Emerging drugs for amyotrophic lateral sclerosis ⬇️

scientific article published on August 1, 2011

Estimating daily energy expenditure in individuals with amyotrophic lateral sclerosis

scientific article published on 12 February 2014

Excellent inter‐rater, intra‐rater, and telephone‐administered reliability of the ALSFRS‐R in a multicenter clinical trial

article

Experience with the Awaji Island modifications to the ALS diagnostic criteria

scientific article published on 01 November 2010

Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients.

scientific article published on 24 October 2017

Glatiramer acetate immunization induces specific antibody and cytokine responses in ALS patients

article

How common is depression among ALS caregivers? A longitudinal study

scientific article

Hypercaloric enteral nutrition in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled phase 2 trial

scientific article

Identification of a novel D109Y mutation in Cu/Zn superoxide dismutase (sod1) gene associated with amyotrophic lateral sclerosis

scientific article published on 25 January 2007

Improving symptom management for people with amyotrophic lateral sclerosis

scientific article published on 31 May 2017

Infrastructure resources for clinical research in amyotrophic lateral sclerosis

scientific article published on May 2013

Japanese and American ALS patient preferences regarding TIV (tracheostomy with invasive ventilation): a cross-national survey

scientific article published on 10 April 2014

Large scale clinical trials in the field of neurology

scientific article published on 01 November 2010

Long-term treatment with leuprorelin for spinal and bulbar muscular atrophy

scientific article published on 09 August 2017

Longitudinal Screening Detects Cognitive Stability and Behavioral Deterioration in ALS Patients

scientific article published on 31 October 2018

Measures of dyspnea in patients with amyotrophic lateral sclerosis

scientific article published on 01 January 2007

Medical and supportive care among people with ALS in the months before death or tracheostomy.

scientific article published on 18 June 2009

Methionine-free brain-derived neurotrophic factor in wobbler mouse motor neuron disease: dose-related effects and comparison with the methionyl form

scientific article published in July 2002

Modafinil treatment of fatigue in patients with ALS: a placebo-controlled study

scientific article published in March 2009

Motor unit number estimation (MUNE) in diseases of the motor neuron: utility and comparative analysis in a multimodal biomarker study.

scientific article published on January 2009

Multiple system atrophy and amyotrophic lateral sclerosis in a family with hexanucleotide repeat expansions in C9orf72.

scientific article

Necroptosis drives motor neuron death in models of both sporadic and familial ALS.

scientific article

Non-invasive measurement of abnormal ventilatory mechanics in amyotrophic lateral sclerosis

scientific article published on 21 January 2016

Non-invasive ventilation and diaphragmatic pacing in ALS.

scientific article published on 30 July 2015

Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis

scientific article

Nuclear localization of SMN and FUS is not altered in fibroblasts from patients with sporadic ALS

scientific article

Olfactory ensheathing glia injections in Beijing: misleading patients with ALS.

scientific article

Opinions of Japanese and American ALS caregivers regarding tracheostomy with invasive ventilation (TIV).

scientific article published on 07 September 2015

Outcome measures for early phase clinical trials

scientific article published in October 2007

Outcomes research in amyotrophic lateral sclerosis: lessons learned from the amyotrophic lateral sclerosis clinical assessment, research, and education database.

scientific article

Oxidative stress biomarkers in sporadic ALS

scientific article

Palliative care for patients with amyotrophic lateral sclerosis: "prepare for the worst and hope for the best".

scientific article published in July 2007

Parkinsonism and motor neuron diseases: twenty-seven patients with diverse overlap syndromes

scientific article published in September 2010

Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III.

scientific article

Phenotypic and molecular analyses of primary lateral sclerosis

scientific article published on 14 April 2015

Plasma creatinine and oxidative stress biomarkers in amyotrophic lateral sclerosis

scientific article published on 10 April 2020

Potential Environmental Factors in Amyotrophic Lateral Sclerosis

scientific article

Predictors and course of elective long-term mechanical ventilation: A prospective study of ALS patients

scientific article published on June 2006

Primary Lateral Sclerosis

scientific article

Primary Lateral Sclerosis and Early Upper Motor Neuron Disease: Characteristics of a Cross-Sectional Population

scientific article published on March 2016

Primary lateral sclerosis (PLS) functional rating scale: PLS-specific clinimetric scale

scientific article published on 13 December 2019

Primary lateral sclerosis: consensus diagnostic criteria

scientific article published on 06 February 2020

Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia

scientific article published in December 2005

Promoting clinical and patient-oriented research to identify the pathogenesis of amyotrophic lateral sclerosis

scientific article published in May 2013

Promoting excellence in end-of-life care in ALS.

scientific article

Randomized control trials in ALS: lessons learned

scientific article

Randomized double-blind personalized N-of-1 clinical trial to test the safety and potential efficacy of TJ-68 for treating muscle cramps in amyotrophic lateral sclerosis (ALS): study protocol for a TJ-68 trial

scientific article published in 2023

Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis.

scientific article published on 10 February 2016

Rasagiline for amyotrophic lateral sclerosis: A randomized, controlled trial

scientific article published on 26 November 2018

Recent advances in amyotrophic lateral sclerosis research

scientific article

Relationship of creatine kinase to body composition, disease state, and longevity in ALS

scientific article

Research Advances in Amyotrophic Lateral Sclerosis, 2009 to 2010 ⬇️

scientific article published on February 1, 2011

Respiratory measures in amyotrophic lateral sclerosis

scientific article published on 23 March 2018

Response to commentary on a novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS

scientific article published on 01 February 2009

Revised Airlie House consensus guidelines for design and implementation of ALS clinical trials

article

Riluzole slows the progression of neuromuscular dysfunction in the wobbler mouse motor neuron disease

scientific article

Seeking a measure of clinically meaningful change in ALS.

scientific article published on 15 August 2014

Senataxin mutations and amyotrophic lateral sclerosis

scientific article

Sexuality and intimacy in ALS: systematic literature review and future perspectives

scientific article published on 11 December 2018

Sporadic amyotrophic lateral sclerosis and breast cancer: Hyaline conglomerate inclusions lead to identification of SOD1 mutation

scientific article published on 19 January 2006

Telephone based cognitive-behavioral screening for frontotemporal changes in patients with amyotrophic lateral sclerosis (ALS).

scientific article published on 28 April 2016

Ten Most Commonly Asked Questions About Amyotrophic Lateral Sclerosis ⬇️

scientific article published on 01 September 2002

The Awaji criteria for diagnosis of ALS

article

The Current Status of End-of-Life Care in ALS: Progress and Personal Experience from the Past Ten Years in the USA

scientific article published in August 2015

The Dilemma of the Clinical Trialist in Amyotrophic Lateral Sclerosis: The Hurdles to Finding a Cure

scientific article

The Timed Up and Go test: Predicting falls in ALS

article

The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis ⬇️

scientific article published on November 20, 2011

The role of exercise in amyotrophic lateral sclerosis

scientific article published on August 2008

Toward more efficient clinical trials for amyotrophic lateral sclerosis

scientific article published on May 2010

Tracheostomy with invasive ventilation for ALS patients: neurologists' roles in the US and Japan

scientific article published on 05 October 2012

Understanding the use of NIV in ALS: results of an international ALS specialist survey

scientific article published on 16 April 2018

What if you knew the prognosis of your patients with ALS?

scientific article published on 26 March 2018

Whole-genome analysis of sporadic amyotrophic lateral sclerosis

scientific article

Why people play: artificial lives acquiring play instinct to stabilize productivity

scientific article

[A prognostic biomarker in amyotrophic lateral sclerosis]

scientific article published on 29 November 2018

[A strategy to develop effective ALS therapy]

scientific article published on 01 April 2007

[Management and care for patients with ALS]

scientific article published on 01 November 2006

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