List of works - Silvia C Finnemann

Advanced Analysis of Photoreceptor Outer Segment Phagocytosis by RPE Cells in Culture

article

Alphavbeta5 integrin receptors at the apical surface of the RPE: one receptor, two functions.

scientific article published on January 2008

Altered rhythm of photoreceptor outer segment phagocytosis in beta5 integrin knockout mice.

scientific article published on January 2006

Analysis of photoreceptor outer segment phagocytosis by RPE cells in culture

scientific article published on January 2013

Analysis of photoreceptor rod outer segment phagocytosis by RPE cells in situ

scientific article

Annexin A5 regulates surface αvβ5 integrin for retinal clearance phagocytosis

scientific article published on 16 October 2019

Changes in retinal pigment epithelial gene expression induced by rod outer segment uptake

scientific article

Comment on 'Integrin alphavbbeta is not required for the phagocytosis of photoreceptor outer segments by cultured retinal pigment epithelial cells' by M.O. Hall, T.A. Abrams and B.L. Burgess [Exp. Eye Res. 77 (2003) 281-286].

scientific article

Dietary antioxidants prevent age-related retinal pigment epithelium actin damage and blindness in mice lacking αvβ5 integrin

scientific article published on 8 December 2011

Differences in Diurnal Rhythm of Rod Outer Segment Renewal between 129T2/SvEmsJ and C57BL/6J Mice

scientific article published in 2022

Dimerization deficiency of enigmatic retinitis pigmentosa-linked rhodopsin mutants

scientific article published on 03 October 2016

Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but notItgb5−/−orMfge8−/−mouse retina ⬇️

scientific article published on May 7, 2012

Efficiency of Membrane Protein Expression Following Infection with Recombinant Adenovirus of Polarized Non-Transformed Human Retinal Pigment Epithelial Cells.

scientific article published on January 2016

Essential diurnal Rac1 activation during retinal phagocytosis requires αvβ5 integrin but not tyrosine kinases focal adhesion kinase or Mer tyrosine kinase ⬇️

scientific article published on January 19, 2012

Essential role for MFG-E8 as ligand for alphavbeta5 integrin in diurnal retinal phagocytosis

scholarly article

Expression and Characterisation of αvβ5 Integrin on Intestinal Macrophages

scientific article published on 20 April 2018

Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration

article published in the Proceedings of the National Academy of Sciences of the United States of America

Expression of the Integrin Coreceptor Transglutaminase-2 in the RPE In Vivo and in Culture ⬇️

scientific article published on January 1, 2012

Focal adhesion kinase signaling promotes phagocytosis of integrin-bound photoreceptors

scientific journal article

Independent roles of methionine sulfoxide reductase A in mitochondrial ATP synthesis and as antioxidant in retinal pigment epithelial cells

scientific article published on 10 October 2013

Lack of alphavbeta5 integrin receptor or its ligand MFG-E8: distinct effects on retinal function

scientific article published on 18 April 2008

Lack of effect of microfilament or microtubule cytoskeleton-disrupting agents on restriction of externalized phosphatidylserine to rod photoreceptor outer segment tips.

scientific article published in January 2014

Large-scale purification of porcine or bovine photoreceptor outer segments for phagocytosis assays on retinal pigment epithelial cells

scientific article

Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for modulating outer segment phagocytosis under oxidant stress conditions.

scientific article published on 13 December 2005

Live Imaging of LysoTracker-Labelled Phagolysosomes Tracks Diurnal Phagocytosis of Photoreceptor Outer Segment Fragments in Rat RPE Tissue Ex Vivo.

scientific article published in January 2016

Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin.

scientific article

MerTK activation during RPE phagocytosis in vivo requires alphaVbeta5 integrin

scientific article published in January 2006

Microglia Inhibition Delays Retinal Degeneration Due to MerTK Phagocytosis Receptor Deficiency

scientific article published on 16 July 2020

Neural retina and MerTK-independent apical polarity of alphavbeta5 integrin receptors in the retinal pigment epithelium

scientific article

No Difference Between Age-Matched Male and Female C57BL/6J Mice in Photopic and Scotopic Electroretinogram a- and b-Wave Amplitudes or in Peak Diurnal Outer Segment Phagocytosis by the Retinal Pigment Epithelium

scientific article published on 01 January 2019

Non-invasive in vivo fluorescence imaging of apoptotic retinal photoreceptors

scientific article published in Scientific Reports

Nonsynaptic localization of the excitatory amino acid transporter 4 in photoreceptors.

scientific article published on March 2005

Novel role for alphavbeta5-integrin in retinal adhesion and its diurnal peak

scientific article published on 7 December 2005

PI 3-kinase independent role for AKT in F-actin regulation during outer segment phagocytosis by RPE cells

scientific article published on 10 May 2013

Quantified F-Actin Morphology Is Predictive of Phagocytic Capacity of Stem Cell-Derived Retinal Pigment Epithelium

scientific article

Regulation of Phagolysosomal Digestion by Caveolin-1 of the Retinal Pigment Epithelium Is Essential for Vision

scientific article published on 26 January 2016

Regulation of phagocytosis by Rho GTPases

scientific article

Retinal Pre-Conditioning by CD59a Knockout Protects against Light-Induced Photoreceptor Degeneration.

scientific article

Retinal pigment epithelial cells use a MerTK-dependent mechanism to limit the phagocytic particle binding activity of αvβ5 integrin

scientific article published on 5 March 2012

Role of alphavbeta5 integrin in regulating phagocytosis by the retinal pigment epithelium.

scientific article published on January 2003

Semaphorin4D-PlexinB1 Signaling Attenuates Photoreceptor Outer Segment Phagocytosis by Reducing Rac1 Activity of RPE Cells

scientific article published on 17 June 2017

Sex-specific multi-level 3D genome dynamics in the mouse brain

scientific article published on 01 January 2022

Tetraspanin CD81 is required for the alpha v beta5-integrin-dependent particle-binding step of RPE phagocytosis

scientific journal article

The Developmental Stage of Adult Human Stem Cell-Derived Retinal Pigment Epithelium Cells Influences Transplant Efficacy for Vision Rescue

scientific article published on 13 June 2017

The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells

scientific article published on 10 July 2008

The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells.

scientific article

The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium

scientific article

The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells

scholarly article

Tissue-specific modifier alleles determine Mertk loss-of-function traits

scientific article published in 2022

Understanding photoreceptor outer segment phagocytosis: use and utility of RPE cells in culture

scientific article

αvβ5 Integrin-Dependent Diurnal Phagocytosis of Shed Photoreceptor Outer Segments by RPE Cells Is Independent of the Integrin Coreceptor Transglutaminase-2 ⬇️

scientific article published on January 1, 2012

List of works by Silvia C Finnemann

Advanced Analysis of Photoreceptor Outer Segment Phagocytosis by RPE Cells in Culture

Alphavbeta5 integrin receptors at the apical surface of the RPE: one receptor, two functions.

Altered rhythm of photoreceptor outer segment phagocytosis in beta5 integrin knockout mice.

Analysis of photoreceptor outer segment phagocytosis by RPE cells in culture

Analysis of photoreceptor rod outer segment phagocytosis by RPE cells in situ

Annexin A5 regulates surface αvβ5 integrin for retinal clearance phagocytosis

Changes in retinal pigment epithelial gene expression induced by rod outer segment uptake

Comment on 'Integrin alphavbbeta is not required for the phagocytosis of photoreceptor outer segments by cultured retinal pigment epithelial cells' by M.O. Hall, T.A. Abrams and B.L. Burgess [Exp. Eye Res. 77 (2003) 281-286].

Dietary antioxidants prevent age-related retinal pigment epithelium actin damage and blindness in mice lacking αvβ5 integrin

Differences in Diurnal Rhythm of Rod Outer Segment Renewal between 129T2/SvEmsJ and C57BL/6J Mice

Dimerization deficiency of enigmatic retinitis pigmentosa-linked rhodopsin mutants

Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but notItgb5−/−orMfge8−/−mouse retina ⬇️

Efficiency of Membrane Protein Expression Following Infection with Recombinant Adenovirus of Polarized Non-Transformed Human Retinal Pigment Epithelial Cells.

Essential diurnal Rac1 activation during retinal phagocytosis requires αvβ5 integrin but not tyrosine kinases focal adhesion kinase or Mer tyrosine kinase ⬇️

Essential role for MFG-E8 as ligand for alphavbeta5 integrin in diurnal retinal phagocytosis

Expression and Characterisation of αvβ5 Integrin on Intestinal Macrophages

Expression of ABCA4 in the retinal pigment epithelium and its implications for Stargardt macular degeneration

Expression of the Integrin Coreceptor Transglutaminase-2 in the RPE In Vivo and in Culture ⬇️

Focal adhesion kinase signaling promotes phagocytosis of integrin-bound photoreceptors

Independent roles of methionine sulfoxide reductase A in mitochondrial ATP synthesis and as antioxidant in retinal pigment epithelial cells

Lack of alphavbeta5 integrin receptor or its ligand MFG-E8: distinct effects on retinal function

Lack of effect of microfilament or microtubule cytoskeleton-disrupting agents on restriction of externalized phosphatidylserine to rod photoreceptor outer segment tips.

Large-scale purification of porcine or bovine photoreceptor outer segments for phagocytosis assays on retinal pigment epithelial cells

Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for modulating outer segment phagocytosis under oxidant stress conditions.

Live Imaging of LysoTracker-Labelled Phagolysosomes Tracks Diurnal Phagocytosis of Photoreceptor Outer Segment Fragments in Rat RPE Tissue Ex Vivo.

Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin.

MerTK activation during RPE phagocytosis in vivo requires alphaVbeta5 integrin

Microglia Inhibition Delays Retinal Degeneration Due to MerTK Phagocytosis Receptor Deficiency

Neural retina and MerTK-independent apical polarity of alphavbeta5 integrin receptors in the retinal pigment epithelium

No Difference Between Age-Matched Male and Female C57BL/6J Mice in Photopic and Scotopic Electroretinogram a- and b-Wave Amplitudes or in Peak Diurnal Outer Segment Phagocytosis by the Retinal Pigment Epithelium

Non-invasive in vivo fluorescence imaging of apoptotic retinal photoreceptors

Nonsynaptic localization of the excitatory amino acid transporter 4 in photoreceptors.

Novel role for alphavbeta5-integrin in retinal adhesion and its diurnal peak

PI 3-kinase independent role for AKT in F-actin regulation during outer segment phagocytosis by RPE cells

Quantified F-Actin Morphology Is Predictive of Phagocytic Capacity of Stem Cell-Derived Retinal Pigment Epithelium

Regulation of Phagolysosomal Digestion by Caveolin-1 of the Retinal Pigment Epithelium Is Essential for Vision

Regulation of phagocytosis by Rho GTPases

Retinal Pre-Conditioning by CD59a Knockout Protects against Light-Induced Photoreceptor Degeneration.

Retinal pigment epithelial cells use a MerTK-dependent mechanism to limit the phagocytic particle binding activity of αvβ5 integrin

Role of alphavbeta5 integrin in regulating phagocytosis by the retinal pigment epithelium.

Semaphorin4D-PlexinB1 Signaling Attenuates Photoreceptor Outer Segment Phagocytosis by Reducing Rac1 Activity of RPE Cells

Sex-specific multi-level 3D genome dynamics in the mouse brain

Tetraspanin CD81 is required for the alpha v beta5-integrin-dependent particle-binding step of RPE phagocytosis

The Developmental Stage of Adult Human Stem Cell-Derived Retinal Pigment Epithelium Cells Influences Transplant Efficacy for Vision Rescue

The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells

The age lipid A2E and mitochondrial dysfunction synergistically impair phagocytosis by retinal pigment epithelial cells.

The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epithelium

The lipofuscin fluorophore A2E perturbs cholesterol metabolism in retinal pigment epithelial cells

Tissue-specific modifier alleles determine Mertk loss-of-function traits

Understanding photoreceptor outer segment phagocytosis: use and utility of RPE cells in culture

αvβ5 Integrin-Dependent Diurnal Phagocytosis of Shed Photoreceptor Outer Segments by RPE Cells Is Independent of the Integrin Coreceptor Transglutaminase-2 ⬇️