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List of works by Szabolcs Fekete

A generic workflow for the characterization of therapeutic monoclonal antibodies-application to daratumumab

scientific article published on 07 January 2019

A workflow for column interchangeability in liquid chromatography using modeling software and quality-by-design principles

scientific article published in September 2017

Achievable separation performance and analysis time in current liquid chromatographic practice for monoclonal antibody separations

scientific article published on 12 April 2017

Adsorption and recovery issues of recombinant monoclonal antibodies in reversed-phase liquid chromatography

scientific article published on 09 December 2014

Analysis of Sub g/kg Lincomycin in Honey, Muscle, Milk, and Eggs Using Fast Liquid Chromatography-Tandem Mass Spectrometry

scientific article published on 01 March 2012

Analysis of antibody-drug conjugates by comprehensive on-line two-dimensional hydrophobic interaction chromatography x reversed phase liquid chromatography hyphenated to high resolution mass spectrometry. I - Optimization of separation conditions

scientific article published on 28 June 2016

Analysis of antibody-drug conjugates by comprehensive on-line two-dimensional hydrophobic interaction chromatography x reversed phase liquid chromatography hyphenated to high resolution mass spectrometry. II- Identification of sub-units for the char

scientific article published on 28 June 2016

Analysis of recombinant monoclonal antibodies by RPLC: toward a generic method development approach

scientific article published on 23 June 2012

Analysis of recombinant monoclonal antibodies in hydrophilic interaction chromatography: A generic method development approach

scientific article published on 15 June 2017

Apparent efficiency of serially coupled columns in gradient elution liquid chromatography: Extension to the combination of any column formats

scientific article published on 18 December 2018

Apparent efficiency of serially coupled columns in isocratic and gradient elution modes

scientific article published on 02 August 2018

Characterization of 30 therapeutic antibodies and related products by size exclusion chromatography: Feasibility assessment for future mass spectrometry hyphenation.

scientific article

Characterization of an antibody-drug conjugate by hydrophilic interaction chromatography coupled to mass spectrometry

scientific article published on 20 February 2018

Characterization of cation exchanger stationary phases applied for the separations of therapeutic monoclonal antibodies

scientific article published on 7 April 2015

Characterization of new types of stationary phases for fast liquid chromatographic applications.

scientific article published on 6 June 2009

Characterizing various monoclonal antibodies with milder reversed phase chromatography conditions

scientific article published on 29 July 2018

Chromatographic, Electrophoretic, and Mass Spectrometric Methods for the Analytical Characterization of Protein Biopharmaceuticals

scientific article

Comparative study of new shell-type, sub-2 micron fully porous and monolith stationary phases, focusing on mass-transfer resistance

scientific article published on 2 April 2010

Comparative study of recent wide-pore materials of different stationary phase morphology, applied for the reversed-phase analysis of recombinant monoclonal antibodies

scientific article published on 29 January 2013

Comparison of liquid chromatography and supercritical fluid chromatography coupled to compact single quadrupole mass spectrometer for targeted in vitro metabolism assay.

scientific article published on 24 October 2014

Comparison of originator and biosimilar therapeutic monoclonal antibodies using comprehensive two-dimensional liquid chromatography coupled with time-of-flight mass spectrometry

scientific article published on 30 June 2016

Comparison of the most recent chromatographic approaches applied for fast and high resolution separations: Theory and practice

scientific article published on 06 July 2015

Comparison of various silica-based monoliths for the analysis of large biomolecules

scientific article

Comprehensive study on the effects of sodium and potassium additives in size exclusion chromatographic separations of protein biopharmaceuticals

scientific article published on 26 September 2016

Computer assisted liquid chromatographic method development for the separation of therapeutic proteins.

scientific article

Computer-assisted UHPLC-MS method development and optimization for the determination of 24 antineoplastic drugs used in hospital pharmacy

scientific article published on 06 November 2018

Contribution of various types of liquid chromatography-mass spectrometry instruments to band broadening in fast analysis

scientific article published on 14 August 2013

Corrigendum to "Protocols for the analytical characterization of therapeutic monoclonal antibodies. I-Non-denaturing chromatographic techniques" [J. Chromatogr. B 1058 (2017) 73-84].

scientific article published on 9 October 2017

Coupling non-denaturing chromatography to mass spectrometry for the characterization of monoclonal antibodies and related products

scientific article published on 25 February 2020

Critical evaluation of fast size exclusion chromatographic separations of protein aggregates, applying sub-2 μm particles

scientific article

Current and future trends in UHPLC

scientific article published in 2014

Current and future trends in reversed-phase liquid chromatography-mass spectrometry of therapeutic proteins

scientific article published in September 2020

Current possibilities of liquid chromatography for the characterization of antibody-drug conjugates

scientific article

Cutting-edge multi-level analytical and structural characterization of antibody-drug conjugates: present and future

scientific article published on 18 February 2019

Design and development of a new information technology platform for patients with dementia

scientific article published in January 2017

Determination of isoelectric points and relative charge variants of 23 therapeutic monoclonal antibodies

scientific article published on 22 September 2017

Determination of size variants by CE-SDS for approved therapeutic antibodies: Key implications of subclasses and light chain specificities

scientific article published on 10 February 2020

Development of a fast workflow to screen the charge variants of therapeutic antibodies

scientific article published on 27 February 2017

Development of a rapid method for the determination and confirmation of nitroimidazoles in six matrices by fast liquid chromatography–tandem mass spectrometry

article

Development of an innovative salt-mediated pH gradient cation exchange chromatography method for the characterization of therapeutic antibodies

scientific article published on 07 September 2020

Direct identification of rituximab main isoforms and subunit analysis by online selective comprehensive two-dimensional liquid chromatography-mass spectrometry

scientific article

Editorial for the special issue entitled "Biopharmaceuticals 2016".

scientific article published on 7 July 2016

Editorial for the special issue titled "Biopharmaceuticals 2020"

scientific article published on 22 February 2020

Efficiency of the new sub-2μm core–shell (Kinetex™) column in practice, applied for small and large molecule separation ⬇️

scientific article published on September 19, 2010

Estimation of pressure-, temperature- and frictional heating-related effects on proteins' retention under ultra-high-pressure liquid chromatographic conditions

scientific article published on 17 March 2015

Estimation of the effects of longitudinal temperature gradients caused by frictional heating on the solute retention using fully porous and superficially porous sub-2μm materials

scientific article published on 18 July 2014

Evaluation of a new wide pore core-shell material (Aeris WIDEPORE) and comparison with other existing stationary phases for the analysis of intact proteins

scientific article published on 10 March 2012

Evaluation of a new wide-pore superficially porous material with carbon core and nanodiamond-polymer shell for the separation of proteins

scientific article published on 17 August 2015

Evaluation of new superficially porous particles with carbon core and nanodiamond-polymer shell for proteins characterization

scientific article published on 27 November 2014

Evaluation of recent very efficient wide-pore stationary phases for the reversed-phase separation of proteins

scientific article published on 28 June 2012

Evaluation of size exclusion chromatography columns packed with sub-3μm particles for the analysis of biopharmaceutical proteins

scientific article published on 27 November 2016

Evaluation of stationary phases packed with superficially porous particles for the analysis of pharmaceutical compounds using supercritical fluid chromatography

scientific article published on 01 August 2014

Evolution and Current Trends in Liquid and Supercritical Fluid Chromatography

scientific article published in 2014

Facts and myths about columns packed with sub-3 microm and sub-2 microm particles

scientific article published on 12 August 2009

Fast and sensitive determination of Polysorbate 80 in solutions containing proteins

scientific article published on 03 March 2010

Fast gradient screening of pharmaceuticals with 5 cm long, narrow bore reversed-phase columns packed with sub-3 μm core-shell and sub-2 μm totally porous particles

scientific article published on 26 January 2011

Fast liquid chromatography: the domination of core-shell and very fine particles

scientific article published on 22 September 2011

High resolution reversed phase analysis of recombinant monoclonal antibodies by ultra-high pressure liquid chromatography column coupling

scientific article published on 25 May 2013

Hydrophilic Interaction Chromatography Hyphenated with Mass Spectrometry: A Powerful Analytical Tool for the Comparison of Originator and Biosimilar Therapeutic Monoclonal Antibodies at the Middle-up Level of Analysis

scientific article published on 25 January 2017

Hydrophobic interaction chromatography for the characterization of monoclonal antibodies and related products

scientific article published on 4 April 2016

Impact of mobile phase temperature on recovery and stability of monoclonal antibodies using recent reversed-phase stationary phases

scientific article published on 20 June 2012

Impact of organic modifier and temperature on protein denaturation in hydrophobic interaction chromatography

scientific article published on 26 August 2016

Impact of particle size gradients on the apparent efficiency of chromatographic columns

scientific article published on 25 June 2019

Impact of the column on effluent pH in cation exchange pH gradient chromatography, a practical study

scientific article published on 17 June 2020

Implementation of a generic liquid chromatographic method development workflow: Application to the analysis of phytocannabinoids and Cannabis sativa extracts.

scientific article published on 31 March 2018

Importance of instrumentation for fast liquid chromatography in pharmaceutical analysis

scientific article published on 26 March 2013

Importance of vial shape and type on the reproducibility of size exclusion chromatography measurement of monoclonal antibodies

scientific article published on 21 April 2016

Improving selectivity and performing online on-column fractioning in liquid chromatography for the separation of therapeutic biopharmaceutical products

scientific article published on 21 January 2020

Influence of connection tubing in modern size exclusion chromatography and its impact on the characterization of mAbs

scientific article published on 28 October 2017

Influence of pressure and temperature on molar volume and retention properties of peptides in ultra-high pressure liquid chromatography

scientific article published on 18 August 2013

Investigating the use of unconventional temperatures in supercritical fluid chromatography

scientific article published on 18 August 2020

Ion-exchange chromatography for the characterization of biopharmaceuticals

scientific article published on 26 February 2015

Is hydrophobic interaction chromatography the most suitable technique to characterize site-specific antibody-drug conjugates?

scientific article published on 11 December 2018

Kinetic evaluation of new generation of column packed with 1.3 μm core-shell particles

scientific article

Maximizing kinetic performance in supercritical fluid chromatography using state-of-the-art instruments

scientific article published on 14 September 2013

Method development for the separation of monoclonal antibody charge variants in cation exchange chromatography, Part I: salt gradient approach

scientific article published on 08 September 2014

Method development for the separation of monoclonal antibody charge variants in cation exchange chromatography, Part II: pH gradient approach

scientific article published on 05 October 2014

Negative gradient slope methods to improve the separation of closely eluting proteins

scientific article published on 23 November 2020

New developments and possibilities of wide-pore superficially porous particle technology applied for the liquid chromatographic analysis of therapeutic proteins

scientific article published on 05 June 2018

New trends in reversed-phase liquid chromatographic separations of therapeutic peptides and proteins: theory and applications

scientific article

Optimization of non-linear gradient in hydrophobic interaction chromatography for the analytical characterization of antibody-drug conjugates

scientific article published on 16 December 2016

Orthogonal Middle-up Approaches for Characterization of the Glycan Heterogeneity of Etanercept by Hydrophilic Interaction Chromatography Coupled to High-Resolution Mass Spectrometry

scientific article published on 13 December 2018

Possibilities of new generation columns packed with 1.3μm core-shell particles in gradient elution mode

scientific article published on 26 October 2013

Potential of hydrophilic interaction chromatography for the analytical characterization of protein biopharmaceuticals

scientific article published on 22 April 2016

Practical considerations on the particle size and permeability of ion-exchange columns applied to biopharmaceutical separations

scientific article published on 27 August 2019

Practical method development for the separation of monoclonal antibodies and antibody-drug-conjugate species in hydrophobic interaction chromatography, part 1: optimization of the mobile phase

scientific article published on 14 November 2015

Practical method development for the separation of monoclonal antibodies and antibody-drug-conjugate species in hydrophobic interaction chromatoraphy, part 2: Optimization of the phase system

scientific article published on 16 January 2016

Pressure-Enhanced Liquid Chromatography, a Proof of Concept: Tuning Selectivity with Pressure Changes and Gradients

scientific article published in 2022

Proof of Concept To Achieve Infinite Selectivity for the Chromatographic Separation of Therapeutic Proteins

scientific article published on 25 September 2019

Protocols for the analytical characterization of therapeutic monoclonal antibodies. I - Non-denaturing chromatographic techniques.

scientific article

Protocols for the analytical characterization of therapeutic monoclonal antibodies. II - Enzymatic and chemical sample preparation.

scientific article published on 19 June 2017

Protocols for the analytical characterization of therapeutic monoclonal antibodies. III - Denaturing chromatographic techniques hyphenated to mass spectrometry

scientific article published on 21 August 2018

Prototype sphere-on-sphere silica particles for the separation of large biomolecules

scientific article

Pushing the performance limits of reversed-phase ultra high performance liquid chromatography with 1.3μm core-shell particles

scientific article published on 23 August 2013

Rapid high performance liquid chromatography method development with high prediction accuracy, using 5cm long narrow bore columns packed with sub-2microm particles and Design Space computer modeling

scientific article published on 24 September 2009

Recent advances in chromatography for pharmaceutical analysis

scientific article published on 26 November 2018

Reliability of computer-assisted method transfer between several column dimensions packed with 1.3-5μm core-shell particles and between various instruments

scientific article published on 31 January 2014

Reliability of simulated robustness testing in fast liquid chromatography, using state-of-the-art column technology, instrumentation and modelling software.

scientific article

Separation of antibody drug conjugate species by RPLC: A generic method development approach

scientific article published on 11 January 2017

Shell and small particles; evaluation of new column technology

scientific article published on 22 October 2008

Simultaneous determination of eight corticosteroids in bovine tissues using liquid chromatography–tandem mass spectrometry

scientific article published on 01 September 2012

Simultaneous determination of polysorbate 20 and unbound polyethylene-glycol in protein solutions using new core–shell reversed phase column and condensation nucleation light scattering detection ⬇️

scientific article published on August 13, 2010

Size Exclusion and Ion Exchange Chromatographic Hardware Modified with a Hydrophilic Hybrid Surface

scientific article published in 2022

Systematic comparison of a new generation of columns packed with sub-2 μm superficially porous particles

scientific article published on 06 January 2014

Systematic evaluation of mobile phase additives for the LC-MS characterization of therapeutic proteins

scientific article published on 13 January 2015

The effect of pressure and mobile phase velocity on the retention properties of small analytes and large biomolecules in ultra-high pressure liquid chromatography

scientific article published on 03 November 2012

The impact of extra-column band broadening on the chromatographic efficiency of 5 cm long narrow-bore very efficient columns

scientific article published on 17 June 2011

The importance of system band broadening in modern size exclusion chromatography

scientific article

Theory and practice of size exclusion chromatography for the analysis of protein aggregates

scientific article

Therapeutic Fc-fusion proteins: Current analytical strategies

scientific article published on 11 September 2020

Tuning selectivity in cation-exchange chromatography applied for monoclonal antibody separations, part 1: Alternative mobile phases and fine tuning of the separation

scientific article published on 19 February 2019

Tuning selectivity in cation-exchange chromatography applied for monoclonal antibody separations, part 2: Evaluation of recent stationary phases

scientific article published on 05 May 2019

Unraveling the mysteries of modern size exclusion chromatography - the way to achieve confident characterization of therapeutic proteins

scientific article published on 18 June 2018

Updating the European Pharmacopoeia impurity profiling method for terazosin and suggesting alternative columns

scientific article published on 19 May 2020

Use of Ultra-short Columns for Therapeutic Protein Separations, Part 2: Designing the Optimal Column Dimension for Reversed-Phase Liquid Chromatography

scientific article published on 11 December 2020

Use of Ultrashort Columns for Therapeutic Protein Separations. Part 1: Theoretical Considerations and Proof of Concept

scientific article published on 17 December 2020

Utility of a high coverage phenyl-bonding and wide-pore superficially porous particle for the analysis of monoclonal antibodies and related products.

scientific article published on 21 March 2018

Validated UPLC method for the fast and sensitive determination of steroid residues in support of cleaning validation in formulation area

scientific article published on 27 December 2008

α-Azido ketones. Part 7: synthesis of 1,4-disubstituted triazoles by the "click" reaction of various terminal acetylenes with phenacyl azides or α-azidobenzo(hetera)cyclanones

scientific article published on 04 February 2012

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