List of works - Herbert L Bonkovsky

A phase 1/2, dose-escalation trial of deferasirox for the treatment of iron overload in HFE-related hereditary hemochromatosis

scientific article

A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus

scientific article

Acute Hepatic Porphyrias: Review and Recent Progress

scientific article published on 20 December 2018

Advances in the management of erythropoietic protoporphyria - role of afamelanotide

scientific article

An IL28B Genotype-Based Clinical Prediction Model for Treatment of Chronic Hepatitis C ⬇️

scientific article (publication date: 2011)

Association of hepatitis C virus infection with serum iron status: analysis of data from the third National Health and Nutrition Examination Survey

scientific article

Blunted cytopenias and weight loss: new correlates of virologic null response to re-treatment of chronic hepatitis C.

scientific article

Clinically important features of porphyrin and heme metabolism and the porphyrias

scientific article

Comparison of amplification enzymes for Hepatitis C Virus quasispecies analysis

scientific article

Complication rate of percutaneous liver biopsies among persons with advanced chronic liver disease in the HALT-C trial

scientific article

Contemporary clinical research of traditional Chinese medicines for chronic hepatitis B in China: an analytical review

scientific article

Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group

scientific article published in PLoS ONE

Des-gamma-carboxy prothrombin and alpha-fetoprotein as biomarkers for the early detection of hepatocellular carcinoma

scientific article

Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin

scientific article

EXPLORE: A Prospective, Multinational, Natural History Study of Patients with Acute Hepatic Porphyria with Recurrent Attacks

scientific article published on 12 September 2019

Editorial: hepatitis C and porphyria cutanea tarda in 2020

scientific article published on 01 June 2020

Effects of a single dose of oral iron on hepcidin concentrations in human urine and serum analyzed by a robust LC-MS/MS method

scientific article

Excess mortality in patients with advanced chronic hepatitis C treated with long-term peginterferon.

scientific article

Extended interferon-alpha therapy accelerates telomere length loss in human peripheral blood T lymphocytes

scientific article

Genetic Polymorphisms Implicated in Nonalcoholic Liver Disease or Selected Other Disorders Have No Influence on Drug-Induced Liver Injury

scientific article published on 06 June 2019

Heme oxygenase: recent advances in understanding its regulation and role.

scientific article

Hemochromatosis and porphyria.

scientific article

Hepatitis B and liver transplantation: molecular and clinical features that influence recurrence and outcome

scientific article

Hepatitis C, porphyria cutanea tarda and liver iron: an update ⬇️

scientific article published on April 17, 2012

Hepatocellular Carcinoma in Acute Hepatic Porphyrias: Results from the Longitudinal Study of the U.S. Porphyrias Consortium

scientific article published on 18 July 2020

Intestinal expression of genes involved in iron absorption in humans

scientific article (publication date: April 2002)

Iron Levels in Hepatocytes and Portal Tract Cells Predict Progression and Outcomes of Patients With Advanced Chronic Hepatitis C ⬇️

scientific article published on February 15, 2011

Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network

scientific article

Liver injury from tumor necrosis factor-α antagonists: analysis of thirty-four cases

scientific article (publication date: May 2013)

Liver transplantation for erythropoietic protoporphyria liver disease.

scientific article

Lon Peptidase 1 (LONP1)-dependent Breakdown of Mitochondrial 5-Aminolevulinic Acid Synthase Protein by Heme in Human Liver Cells ⬇️

scientific article published on June 9, 2011

Maintenance peginterferon therapy and other factors associated with hepatocellular carcinoma in patients with advanced hepatitis C

scientific article

Management of nonalcoholic steatohepatitis: an analytic review

scientific article

Metabolic and functional differences between brain and spinal cord mitochondria underlie different predisposition to pathology

scientific article

MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression in human hepatoma cells expressing hepatitis C viral proteins

scientific article

Neonatal Androgenization Exacerbates Alcohol-Induced Liver Injury in Adult Rats, an Effect Abrogated by Estrogen ⬇️

scientific article published on December 20, 2011

Novel role of nuclear receptor Rev-erbα in hepatic stellate cell activation: potential therapeutic target for liver injury

scientific journal article

Outcome of sustained virological responders with histologically advanced chronic hepatitis C.

scientific article

Predicting clinical and histologic outcomes based on standard laboratory tests in advanced chronic hepatitis C.

scientific article

Profiles of serum cytokines in acute drug-induced liver injury and their prognostic significance

scientific article (publication date: 2013)

Prolonged Therapy of Advanced Chronic Hepatitis C with Low-Dose Peginterferon

scientific article

Recent insights into the biological functions of liver fatty acid binding protein 1

scientific article

Reciprocal Effects of Micro-RNA-122 on Expression of Heme Oxygenase-1 and Hepatitis C Virus Genes in Human Hepatocytes

scientific article (publication date: October 2007)

Recommendations for the diagnosis and treatment of the acute porphyrias

scientific article

Role of Bach-1 in regulation of heme oxygenase-1 in human liver cells: insights from studies with small interfering RNAS

scientific article

Spectrum of statin hepatotoxicity: experience of the drug-induced liver injury network

scientific article

Structural analysis of heme proteins: implications for design and prediction

scientific article

Tissue-specific expression of ALA synthase-1 and heme oxygenase-1 and their expression in livers of rats chronically exposed to ethanol

scientific journal article

Vascular endothelial growth factor increases heme oxygenase-1 protein expression in the chick embryo chorioallantoic membrane

scientific article

Vascular endothelium as a contributor of plasma sphingosine 1-phosphate

scientific article

List of works by Herbert L Bonkovsky

A phase 1/2, dose-escalation trial of deferasirox for the treatment of iron overload in HFE-related hereditary hemochromatosis

A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus

Acute Hepatic Porphyrias: Review and Recent Progress

Advances in the management of erythropoietic protoporphyria - role of afamelanotide

An IL28B Genotype-Based Clinical Prediction Model for Treatment of Chronic Hepatitis C ⬇️

Association of hepatitis C virus infection with serum iron status: analysis of data from the third National Health and Nutrition Examination Survey

Blunted cytopenias and weight loss: new correlates of virologic null response to re-treatment of chronic hepatitis C.

Clinically important features of porphyrin and heme metabolism and the porphyrias

Comparison of amplification enzymes for Hepatitis C Virus quasispecies analysis

Complication rate of percutaneous liver biopsies among persons with advanced chronic liver disease in the HALT-C trial

Contemporary clinical research of traditional Chinese medicines for chronic hepatitis B in China: an analytical review

Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group

Des-gamma-carboxy prothrombin and alpha-fetoprotein as biomarkers for the early detection of hepatocellular carcinoma

Differential regulation of human ALAS1 mRNA and protein levels by heme and cobalt protoporphyrin

EXPLORE: A Prospective, Multinational, Natural History Study of Patients with Acute Hepatic Porphyria with Recurrent Attacks

Editorial: hepatitis C and porphyria cutanea tarda in 2020

Effects of a single dose of oral iron on hepcidin concentrations in human urine and serum analyzed by a robust LC-MS/MS method

Excess mortality in patients with advanced chronic hepatitis C treated with long-term peginterferon.

Extended interferon-alpha therapy accelerates telomere length loss in human peripheral blood T lymphocytes

Genetic Polymorphisms Implicated in Nonalcoholic Liver Disease or Selected Other Disorders Have No Influence on Drug-Induced Liver Injury

Heme oxygenase: recent advances in understanding its regulation and role.

Hemochromatosis and porphyria.

Hepatitis B and liver transplantation: molecular and clinical features that influence recurrence and outcome

Hepatitis C, porphyria cutanea tarda and liver iron: an update ⬇️

Hepatocellular Carcinoma in Acute Hepatic Porphyrias: Results from the Longitudinal Study of the U.S. Porphyrias Consortium

Intestinal expression of genes involved in iron absorption in humans

Iron Levels in Hepatocytes and Portal Tract Cells Predict Progression and Outcomes of Patients With Advanced Chronic Hepatitis C ⬇️

Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network

Liver injury from tumor necrosis factor-α antagonists: analysis of thirty-four cases

Liver transplantation for erythropoietic protoporphyria liver disease.

Lon Peptidase 1 (LONP1)-dependent Breakdown of Mitochondrial 5-Aminolevulinic Acid Synthase Protein by Heme in Human Liver Cells ⬇️

Maintenance peginterferon therapy and other factors associated with hepatocellular carcinoma in patients with advanced hepatitis C

Management of nonalcoholic steatohepatitis: an analytic review

Metabolic and functional differences between brain and spinal cord mitochondria underlie different predisposition to pathology

MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression in human hepatoma cells expressing hepatitis C viral proteins

Neonatal Androgenization Exacerbates Alcohol-Induced Liver Injury in Adult Rats, an Effect Abrogated by Estrogen ⬇️

Novel role of nuclear receptor Rev-erbα in hepatic stellate cell activation: potential therapeutic target for liver injury

Outcome of sustained virological responders with histologically advanced chronic hepatitis C.

Predicting clinical and histologic outcomes based on standard laboratory tests in advanced chronic hepatitis C.

Profiles of serum cytokines in acute drug-induced liver injury and their prognostic significance

Prolonged Therapy of Advanced Chronic Hepatitis C with Low-Dose Peginterferon

Recent insights into the biological functions of liver fatty acid binding protein 1

Reciprocal Effects of Micro-RNA-122 on Expression of Heme Oxygenase-1 and Hepatitis C Virus Genes in Human Hepatocytes

Recommendations for the diagnosis and treatment of the acute porphyrias

Role of Bach-1 in regulation of heme oxygenase-1 in human liver cells: insights from studies with small interfering RNAS

Spectrum of statin hepatotoxicity: experience of the drug-induced liver injury network

Structural analysis of heme proteins: implications for design and prediction

Tissue-specific expression of ALA synthase-1 and heme oxygenase-1 and their expression in livers of rats chronically exposed to ethanol

Vascular endothelial growth factor increases heme oxygenase-1 protein expression in the chick embryo chorioallantoic membrane

Vascular endothelium as a contributor of plasma sphingosine 1-phosphate