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List of works by Rudolf Jaenisch

3D Chromosome Regulatory Landscape of Human Pluripotent Cells.

scientific article

A 450 kb transgene displays properties of the mammalian X-inactivation center.

scientific article published in July 1996

A Latent Pro-Survival Function for the Mir-290-295 Cluster in Mouse Embryonic Stem Cells ⬇️

scientific article published on May 5, 2011

A Possible Role Of Microglia In Zika Virus Infection Of The Fetal Human Brain

scholarly article published 26 May 2017

A Systematic Approach to Identify Candidate Transcription Factors that Control Cell Identity

scientific article

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

scientific article (publication date: 21 April 2006)

A chromatin landmark and transcription initiation at most promoters in human cells

scientific article (publication date: 13 July 2007)

A conversation with Rudolf Jaenisch

scientific article published in September 2015

A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival

scientific article published in November 2001

A drug-inducible system for direct reprogramming of human somatic cells to pluripotency

scientific article

A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types

scientific article published on July 2008

A method for high efficiency YAC lipofection into murine embryonic stem cells

scientific article

A role for p75 receptor in neurotrophin-3 functioning during the development of limb proprioception

article

A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation

scientific article

A short DNA methyltransferase isoform restores methylation in vivo

scientific article published in December 1998

A stochastic model dissects cell states in biological transition processes

scientific article published on 17 January 2014

Ablation of de novo DNA methyltransferase Dnmt3a in the nervous system leads to neuromuscular defects and shortened lifespan

Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei

scientific article

Abrogation of resistance to Theiler's virus-induced demyelination in H-2b mice deficient in beta 2-microglobulin

scientific article published in July 1993

Activation and transposition of endogenous retroviral elements in hypomethylation induced tumors in mice

scientific article published on 9 July 2007

Activation of endogenous retroviral genomes in Mov strains of mice

scientific article

Activation of proto-oncogenes by disruption of chromosome neighborhoods.

scientific article

Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction

scientific article published in February 1994

Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell-derived alveolar epithelium

scientific article published on 22 March 2022

Alternative SET/TAFI Promoters Regulate Embryonic Stem Cell Differentiation.

scientific article published on 26 September 2017

An Endogenously Tagged Fluorescent Fusion Protein Library in Mouse Embryonic Stem Cells

scientific article published on 26 September 2017

An X-linked human collagen transgene escapes X inactivation in a subset of cells ⬇️

scientific article published on November 1, 1992

An interview with Rudolf Jaenisch.

scientific article published in June 2015

Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells

scientific article published on 5 December 2008

Analysis of the mouse embryonic stem cell regulatory networks obtained by ChIP-chip and ChIP-PET

scientific article

Antigen-specific B-cell receptor sensitizes B cells to infection by influenza virus

scientific article

Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization

scientific article

At most three ES cells contribute to the somatic lineages of chimeric mice and of mice produced by ES-tetraploid complementation

scientific article published on November 2004

Baculovirus-mediated expression and characterization of the full-length murine DNA methyltransferase

scientific article

Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells

scientific article published in April 1990

Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells. 1990.

scientific article published in May 2010

Blimp1 expression predicts embryonic stem cell development in vitro

scientific article

Blockade of transgenic gamma delta T cell development in beta 2-microglobulin deficient mice.

scientific article published on January 1992

Brain-derived neurotrophic factor is essential for opiate-induced plasticity of noradrenergic neurons.

scientific article

Broader Implications of Defining Standards for the Pluripotency of iPSCs

article

Building Capacity for a Global Genome Editing Observatory: Conceptual Challenges

scientific article published on 02 June 2018

Building Capacity for a Global Genome Editing Observatory: Institutional Design

scientific article published on 08 June 2018

CNS disease models with human pluripotent stem cells in the CRISPR age.

scientific article

Cardiac myocytes derived from murine reprogrammed fibroblasts: intact hormonal regulation, cardiac ion channel expression and development of contractility.

scientific article published in July 2009

Celebrating 10 years of hESC lines: an interview with Rudolf Jaenisch

scientific article published in December 2008

Cell-specific TLR9 trafficking in primary APCs of transgenic TLR9-GFP mice

scientific article published on 12 December 2012

Characterization of a highly variable eutherian microRNA gene

scientific article

Chromatin conformation of integrated Moloney leukemia virus DNA sequences in tissues of BALB/Mo mice and in virus-infected cell lines.

scientific article

Chromatin proteomic profiling reveals novel proteins associated with histone-marked genomic regions

scientific article

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

scientific article (publication date: 12 March 2009)

Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells

scientific article

Chromosomal Instability and Tumors Promoted by DNA Hypomethylation

scientific article published on 01 April 2003

Chromosomal deletion complexes in mice by radiation of embryonic stem cells

scientific article published on March 1997

Chromosomal mapping of four different integration sites of Moloney murine leukemia virus including the locus for alpha 1(I) collagen in mouse

scientific article

Chromosomal position and activation of retroviral genomes inserted into the germ line of mice ⬇️

scientific article published on May 1, 1981

Chromosomal position and specific demethylation in enhancer sequences of germ line-transmitted retroviral genomes during mouse development

scientific article published on September 1985

Chromosomal position or virus mutation permits retrovirus expression in embryonal carcinoma cells

scientific article published in November 1986

Chromosomal silencing and localization are mediated by different domains of Xist RNA ⬇️

scientific article published on January 7, 2002

Clearance of influenza virus respiratory infection in mice lacking class I major histocompatibility complex-restricted CD8+ T cells

scientific article

Cloning of two genetically transmitted Moloney leukemia proviral genomes: correlation between biological activity of the cloned DNA and viral genome activation in the animal

scientific article

Collagen protein abnormalities produced by site-directed mutagenesis of the pro alpha 1(I) gene

scientific article published on 01 January 1989

Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells

scientific article published on 22 August 2010

Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice

scientific article published on 11 November 2015

Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development

scientific article published on 24 January 2013

Commentary: isolated stem cells--patentable as cultural artifacts?

scientific article

Complementary roles of BDNF and NT-3 in vestibular and auditory development

scientific journal article

Conditional deletion of Xist disrupts histone macroH2A localization but not maintenance of X inactivation

scientific article published on 01 August 1999

Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity

scientific article

Conformation of Moloney murine leukaemia proviral sequences in chromatin from leukaemic and nonleukaemic cells ⬇️

scientific article published on January 25, 1979

Conformation of free and of integrated Moloney leukemia virus proviral DNA in preleukemic and leukemic BALB/Mo mice

scientific article published in February 1980

Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells

scientific article (publication date: 8 August 2008)

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia

scientific article

Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity

scientific article

Control of developmental regulators by Polycomb in human embryonic stem cells

scientific article (publication date: 21 April 2006)

Core transcriptional regulatory circuitry in human embryonic stem cells

scientific article

Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy

scientific article

Correction: Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity

scientific article published on 16 December 2020

Corrigendum to “a role for p75 receptor in neurotrophin-3 functioning during the development of limb proprioception”

article

Corrigendum: Failure to replicate the STAP cell phenomenon

scientific article published on 16 December 2015

Corrigendum: Hallmarks of pluripotency

correction of a scholarly article

Corrigendum: Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation

scientific article published on 30 July 2015

Cre-lox-regulated conditional RNA interference from transgenes

scientific article

Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders

scientific article

Cytotoxic Escherichia coli strains encoding colibactin isolated from immunocompromised mice with urosepsis and meningitis

scientific article published on 19 March 2018

DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal

scientific article (publication date: March 2007)

DNA CpG hypomethylation induces heterochromatin reorganization involving the histone variant macroH2A.

scientific article published on 22 March 2005

DNA hypomethylation can activate Xist expression and silence X-linked genes

scientific article published in August 1996

DNA hypomethylation leads to elevated mutation rates ⬇️

scientific article published on September 3, 1998

DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals.

scientific article published in February 2001

DNA methylation and gene expression: endogenous retroviral genome becomes infectious after molecular cloning.

scientific article

DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons

scientific article

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.

scientific article published on 4 October 2009

DNA methylation, genomic imprinting, and mammalian development

scientific article published on January 1993

DNA methylation, retroviruses, and embryogenesis

scientific article published on 01 January 1982

DNA methyltransferase contributes to delayed ischemic brain injury.

scientific article published in May 2000

DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer

scientific article

DNase I sensitivity of endogenous and exogenous proviral genome copies in M-MuLV-induced tumors of mov-3 mice ⬇️

scientific article published on 01 May 1982

De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells

scientific article published on October 1996

De novo DNA methylation by Dnmt3a and Dnmt3b is dispensable for nuclear reprogramming of somatic cells to a pluripotent state

scientific article

De novo methylation and expression of retroviral genomes during mouse embryogenesis

scientific article published in August 1982

De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells

scientific article

Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

scientific article (publication date: March 2001)

Delayed clearance of Sendai virus in mice lacking class I MHC-restricted CD8+ T cells

scientific article published in August 1992

Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression

scientific article published on 19 October 2011

Dependence of developing group Ia afferents on neurotrophin-3

Dependence on p75 for innervation of some sympathetic targets

scientific article

Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2 ⬇️

scientific article published on October 31, 2003

Derivation and manipulation of murine embryonic stem cells

scientific article published in January 2009

Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations.

scientific article published on 13 May 2010

Developmentally regulated alterations in Polycomb repressive complex 1 proteins on the inactive X chromosome

scientific article

Different Roles for Tet1 and Tet2 Proteins in Reprogramming-Mediated Erasure of Imprints Induced by EGC Fusion.

scientific article published in March 2013

Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion

scientific article published on 28 February 2013

Differential role of the low affinity neurotrophin receptor (p75) in retrograde axonal transport of the neurotrophins

scientific article published on 01 June 1995

Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats

scientific article

Differentiation and virus expression in BALB/Mo mice: endogenous Moloney leukemia virus is not activated in hematopoietic cells ⬇️

scientific article published on March 1, 1982

Differentiation of F1 embryonic stem cells into viable male and female mice by tetraploid embryo complementation

scientific article published on 01 January 2003

Direct Reprogramming of Fibroblasts into Embryonic Sertoli-like Cells by Defined Factors ⬇️

scientific article published on September 7, 2012

Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency

Direct cell reprogramming is a stochastic process amenable to acceleration

scientific article

Direct in vivo VH to JH rearrangement violating the 12/23 rule

scientific article

Direct lineage conversion of adult mouse liver cells and B lymphocytes to neural stem cells

scientific article

Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells

scientific article published on 27 August 2007

Direct reprogramming of terminally differentiated mature B lymphocytes to pluripotency

scientific article

Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution

scientific article (publication date: 7 June 2007)

Dissecting direct reprogramming through integrative genomic analysis

scientific article (publication date: 3 July 2008)

Dissecting risk haplotypes in sporadic Alzheimer's disease

scientific article published in April 2015

Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality

scientific article

Dnmt3a Protects Active Chromosome Domains against Cancer-Associated Hypomethylation ⬇️

scientific article published on December 20, 2012

Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing

scientific journal article

Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium

scientific article

Double replacement: strategy for efficient introduction of subtle mutations into the murine Col1a-1 gene by homologous recombination in embryonic stem cells

scientific article

Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs

scientific article published on 15 August 2019

Dynamic relocalization of histone MacroH2A1 from centrosomes to inactive X chromosomes during X inactivation

scientific article

Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells

scientific article

ES cells derived from cloned and fertilized blastocysts are transcriptionally and functionally indistinguishable

scientific article

Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes

scientific article published on 01 July 2007

Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues

scientific article

Editing DNA Methylation in the Mammalian Genome

scientific article published on September 2016

Editing the Epigenome to Tackle Brain Disorders

scientific article published on 07 November 2019

Effect of Dna Hypomethylation on Neural Control of Respiration: A Genetic Model ⬇️

scientific article published on January 1, 2001

Effects of cerebral ischemia in mice lacking DNA methyltransferase 1 in post-mitotic neurons ⬇️

scientific article published on December 4, 2001

Efficient derivation of microglia-like cells from human pluripotent stem cells

scientific article published on 26 September 2016

Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells

scientific article published in January 2006

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

scientific article (publication date: September 2009)

Embryonic lethal mutation in mice induced by retrovirus insertion into the alpha 1(I) collagen gene.

scientific article published in July 1983

Embryonic lethal mutation in mouse collagen I gene causes rupture of blood vessels and is associated with erythropoietic and mesenchymal cell death.

scientific article

Endogenous Moloney leukemia virus in nonviremic Mov substrains of mice carries defects in the proviral genome.

scientific article published on February 1983

Engineered tissues and strategies to overcome challenges in drug development

scientific article published on 25 September 2020

Epigenetic hierarchy governing Nestin expression

scientific article published on May 2009

Epigenetic instability in ES cells and cloned mice

scientific article

Epigenetic memory in induced pluripotent stem cells

scientific article (publication date: 16 September 2010)

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

scientific article

Erratum: TET1 is a tumor suppressor of hematopoietic malignancy

scientific article published on 01 August 2015

Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas

scientific article published on 29 March 2018

Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice

scientific article

Expression of oncogenic K-ras from its endogenous promoter leads to a partial block of erythroid differentiation and hyperactivation of cytokine-dependent signaling pathways

scientific article published on 22 February 2007

Expression of retroviruses during early mouse embryogenesis.

scientific article published in January 1983

Expression pattern of the Rett syndrome gene MeCP2 in primate prefrontal cortex

scientific article published in October 2001

Failure to replicate the STAP cell phenomenon

scientific article published in September 2015

Fibronectin binding site in type I collagen regulates fibronectin fibril formation

scientific article

Flp recombinase regulated lacZ expression at the ROSA26 locus

scientific article published on 01 February 2002

Folate deficiency induces genomic uracil misincorporation and hypomethylation but does not increase DNA point mutations

scientific article published on 09 October 2008

Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase

scientific article published on July 2008

Formation of Human Neuroblastoma in Mouse-Human Neural Crest Chimeras

scientific article published on 05 March 2020

Formation of a full complement of cranial proprioceptors requires multiple neurotrophins

Formation of a full complement of cranial proprioceptors requires multiple neurotrophins

scientific article published on 01 June 2000

Fragile X syndrome patient-derived neurons developing in the mouse brain show FMR1 -dependent phenotypes

scientific article published in 2022

Functional analysis of CX3CR1 in human induced pluripotent stem (iPS) cell-derived microglia-like cells

scientific article published on 24 June 2020

Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro

scientific article

Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome

scientific article

Functional integration of dopaminergic neurons directly converted from mouse fibroblasts

scientific article published on 20 October 2011

Gene targeting in human pluripotent cells

scientific article published on January 2010

Generating genetically modified mice using CRISPR/Cas-mediated genome engineering

scientific article published on 24 July 2014

Generating iPS cells from MEFS through forced expression of Sox-2, Oct-4, c-Myc, and Klf4.

scientific article published on 7 April 2008

Generation of collagenase-resistant collagen by site-directed mutagenesis of murine pro alpha 1(I) collagen gene

scientific article

Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor

scientific article

Generation of iPSCs from cultured human malignant cells

scientific article

Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations

scientific article published on 14 July 2011

Generation of mice from wild-type and targeted ES cells by nuclear cloning

scientific article published in February 2000

Generation of nuclear transfer-derived pluripotent ES cells from cloned Cdx2-deficient blastocysts

scientific article published on 16 October 2005

Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer

scientific article

Genetic Transmission of Moloney Leukemia Virus: Mapping of the Chromosomal Integration Site ⬇️

scientific article published on January 1, 1979

Genetic and chemical correction of cholesterol accumulation and impaired autophagy in hepatic and neural cells derived from Niemann-Pick Type C patient-specific iPS cells.

scientific article

Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation

scientific article (publication date: September 2014)

Genetic engineering of human pluripotent cells using TALE nucleases

scientific article (publication date: 7 July 2011)

Genome-scale DNA methylation maps of pluripotent and differentiated cells

scientific article

Genome-wide CRISPR screen for Zika virus resistance in human neural cells

scientific article published on 24 April 2019

Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

scientific article

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

scientific article

Genomic sequence of mouse COL1A1 encoding the collagen propeptides

scientific article published in December 1993

Germ line integration of Moloney leukemia virus: Identification of the chromosomal integration site ⬇️

scientific article published on April 1, 1979

Germ line transmission of a yeast artificial chromosome spanning the murine alpha 1(I) collagen locus

scientific article published on March 1993

Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes

scientific article published in April 1996

Germline integration of moloney murine leukemia virus at the Mov13 locus leads to recessive lethal mutation and early embryonic death.

scientific article

Global loss of imprinting leads to widespread tumorigenesis in adult mice

scientific article published on October 2005

Global transcriptional and translational repression in human-embryonic-stem-cell-derived Rett syndrome neurons

scientific article

H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment

scientific article

HDAC2 negatively regulates memory formation and synaptic plasticity.

scientific article

Hallmarks of pluripotency

scientific article published on September 2015

Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation

scientific article

High frequency of unequal recombination in pseudoautosomal region shown by proviral insertion in transgenic mouse

scientific article published in Nature

High rate of recombination and double crossovers in the mouse pseudoautosomal region during male meiosis

scientific article

Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication

scientific article

Highly inducible cell lines derived from mice genetically transmitting the Moloney murine leukemia virus genome ⬇️

scientific article published on March 1, 1979

Histone H3K27ac separates active from poised enhancers and predicts developmental state

scientific article

Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs

Human Embryo Editing: Opportunities and Importance of Transnational Cooperation

scientific article published in October 2017

Human Intestinal Tissue with Adult Stem Cell Properties Derived from Pluripotent Stem Cells.

scientific article

Human Naive Pluripotent Stem Cells Model X Chromosome Dampening and X Inactivation

scientific article published on 13 December 2016

Human T Cells Expressing a CD19 CAR-T Receptor Provide Insights into Mechanisms of Human CD19-Positive β Cell Destruction

scientific article published on 22 September 2020

Human cerebral organoids reveal deficits in neurogenesis and neuronal migration in MeCP2-deficient neural progenitors

scientific article published in April 2018

Human cloning - the science and ethics of nuclear transplantation.

scientific article

Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

scientific article

Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain

scientific article published on 26 November 2019

Human induced pluripotent stem cell-derived glial cells and neural progenitors display divergent responses to Zika and dengue infections

article published in the Proceedings of the National Academy of Sciences of the United States of America

Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells

scientific article

Human neural crest cells contribute to coat pigmentation in interspecies chimeras after in utero injection into mouse embryos

scientific article published on 25 January 2016

Hybrid embryonic stem cell-derived tetraploid mice show apparently normal morphological, physiological, and neurological characteristics

scientific article

Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation

scientific article

Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons

scientific article

IgG1 + ovalbumin-specific B-cell transnuclear mice show class switch recombination in rare allelically included B cells ⬇️

scientific article published on August 6, 2012

Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease

scientific article

In Vitro Modeling of Complex Neurological Diseases

In situ genome sequencing resolves DNA sequence and structure in intact biological samples

scientific article published on 31 December 2020

In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

scientific article (publication date: 19 July 2007)

Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development

scientific article published in October 1992

Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei

scientific article published in April 2003

Increase of AKR-specific sequences in tumor tissues of leukemic AKR mice ⬇️

scientific article published on July 1, 1976

Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase

scientific article

Induced Pluripotency and Epigenetic Reprogramming

scientific article

Induced Pluripotent Stem Cells Meet Genome Editing

scientific article

Induction of Expansion and Folding in Human Cerebral Organoids

scientific article (publication date: December 2016)

Induction of Tumors in Mice by Genomic Hypomethylation ⬇️

scientific article (publication date: 18 April 2003)

Infection of developing mouse embryos with murine leukemia virus: tissue specificity and genetic transmission of the virus

scientific article published on January 1, 1976

Infection of preimplantation mouse embryos and of newborn mice with leukemia virus: tissue distribution of viral DNA and RNA and leukemogenesis in the adult animal ⬇️

scientific article published on October 1, 1975

Infectivity and methylation of retroviral genomes is correlated with expression in the animal

scientific article published in October 1981

Infectivity and structure of molecular clones obtained from two genetically transmitted Moloney leukemia proviral genomes

scientific article published on April 1982

Insertion of retrovirus into the first intron of alpha 1(I) collagen gene to embryonic lethal mutation in mice

scientific article

Insertion of the bacterial gpt gene into the germ line of mice by retroviral infection

scientific article published on October 1985

Integration of Moloney leukaemia virus into the germ line of mice: correlation between site of integration and virus activation

scientific article

Interview with Rudolf Jaenisch, M.D.

scientific article

Intravital imaging of mouse embryos

scientific article published on 01 April 2020

Introduction of a selectable gene into different animal tissue by a retrovirus recombinant vector

scientific article

Introduction of the human pro alpha 1(I) collagen gene into pro alpha 1(I)-deficient Mov-13 mouse cells leads to formation of functional mouse-human hybrid type I collagen

scientific article

Ischemic brain damage in mice after selectively modifying BDNF or NT4 gene expression.

scientific article

Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription

scientific article published on 27 November 2013

JIP2 haploinsufficiency contributes to neurodevelopmental abnormalities in human pluripotent stem cell-derived neural progenitors and cortical neurons

scientific article published on 25 June 2018

Jointly reduced inhibition and excitation underlies circuit-wide changes in cortical processing in Rett syndrome

scientific article

Knocking the NT4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT4 and BDNF activities

scientific article (publication date: April 2000)

Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents

scientific article

Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment

scientific article published on 04 December 2018

Long-range cis effects of ectopic X-inactivation centres on a mouse autosome

scientific article

Loss of Tet enzymes compromises proper differentiation of embryonic stem cells

scientific article

Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure

scientific article

Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation

scientific article

Loss of methylation activates Xist in somatic but not in embryonic cells

scientific article

Low-multiplicity infection of Moloney murine leukemia virus in mouse cells: effect on number of viral DNA copies and virus production in producer cells ⬇️

scientific article published on December 1, 1978

MHC Class I Deficiency: Susceptibility to Natural Killer (NK) Cells and Impaired NK Activity ⬇️

scientific article published on July 12, 1991

Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation

scientific article

Mammalian (cytosine-5) methyltransferases cause genomic DNA methylation and lethality in Drosophila

scientific article published in November 1999

Mammalian X Chromosome Inactivation ⬇️

scientific article published on 01 January 1998

Mammalian nuclear transfer

scientific article published on September 2006

Matched Developmental Timing of Donor Cells with the Host Is Crucial for Chimera Formation.

scientific article published on 29 March 2018

Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development

scientific article

Matrix remodeling maintains embryonic stem cell self-renewal by activating Stat3.

scientific article published on June 2013

MeCP2 links heterochromatin condensates and neurodevelopmental disease

scientific article published on 22 July 2020

MeCP2-regulated miRNAs control early human neurogenesis through differential effects on ERK and AKT signaling

scientific article published on 25 April 2017

Mechanisms and models of somatic cell reprogramming ⬇️

scientific article published on June 1, 2013

Mechanisms of gene regulation in human embryos and pluripotent stem cells

scientific article published in December 2017

Medicine. iPSC disease modeling

scientific article published on November 2012

Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist

scientific article

Mesenchymal and adrenergic cell lineage states in neuroblastoma possess distinct immunogenic phenotypes

scientific article published in 2022

Messenger RNAs encoding mouse histone macroH2A1 isoforms are expressed at similar levels in male and female cells and result from alternative splicing

scientific article

Metastable Pluripotent States in NOD-Mouse-Derived ESCs

scholarly article by Jacob Hanna et al published August 2015 in Cell Stem Cell

Metastable Pluripotent States in NOD-Mouse-Derived ESCs

scholarly article by Jacob Hanna et al published May 2015 in Cell Stem Cell

Metastable Pluripotent States in NOD-Mouse-Derived ESCs

Metastable pluripotent states in NOD-mouse-derived ESCs

scientific article

Methylation, expression and chromosomal position of genes in mammals ⬇️

scientific article published on May 15, 1984

Mice cloned from olfactory sensory neurons

scientific article

Mice lacking brain-derived neurotrophic factor develop with sensory deficits

scientific article published on March 1994

Mice lacking major histocompatibility complex class I and class II molecules

scientific article

Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype

Microfluidic control of cell pairing and fusion

scientific article published on 4 January 2009

Microinjection of cloned retroviral genomes into mouse zygotes: integration and expression in the animal

scientific article published in October 1981

Micromanipulating dosage compensation: understanding X-chromosome inactivation through nuclear transplantation

scientific article published on December 2003

Mir-290-295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects

scientific article

Mitogenicity of DNA from different organisms for murine B cells ⬇️

scientific article published on October 1, 1997

Molecular Criteria for Defining the Naive Human Pluripotent State.

scientific article published on 13 July 2016

Molecular analysis of the Mov 34 mutation: transcript disrupted by proviral integration in mice is conserved in Drosophila

scientific article

Molecular control of induced pluripotency

scientific article

Molecular control of pluripotency

scientific article published on 22 August 2006

Monitoring Dynamics of DNA Methylation at Single-Cell Resolution during Development and Disease

scientific article published on 02 October 2015

Monoclonal mice generated by nuclear transfer from mature B and T donor cells

scientific article published on 10 February 2002

Most gamma delta T cells develop normally in beta 2-microglobulin-deficient mice ⬇️

scientific article published on January 15, 1992

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

scientific article published on 27 August 2013

Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state

scientific article

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

scientific article

Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase

scientific article

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

scientific article published on November 19, 1992

NT-3 facilitates hippocampal plasticity and learning and memory by regulating neurogenesis

scientific article

Nanoparticles for gene transfer to human embryonic stem cell colonies

scientific article published on 29 August 2008

Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease

scientific article (publication date: 15 April 2008)

Neurotrophin-3 and trkC in muscle are non-essential for the development of mouse muscle spindles ⬇️

scientific article published on March 30, 1998

Neurotrophin-3 modulates noradrenergic neuron function and opiate withdrawal

scientific article published in September 2001

Neurotrophin-3 promotes cell death induced in cerebral ischemia, oxygen-glucose deprivation, and oxidative stress: possible involvement of oxygen free radicals

scientific article published in February 2002

New advances in iPS cell research do not obviate the need for human embryonic stem cells

scientific article published on 01 October 2007

Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a.

scientific article published on May 2000

Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice.

scientific article published in May 2001

Normal development and growth of mice carrying a targeted disruption of the alpha 1 retinoic acid receptor gene

scientific article

Normal epithelial branching morphogenesis in the absence of collagen I

scientific article published on 01 October 1986

Normal eye-specific patterning of retinal inputs to murine subcortical visual nuclei in the absence of brain-derived neurotrophic factor

scientific journal article

Nuclear Cloning and Direct Reprogramming: The Long and the Short Path to Stockholm ⬇️

scientific article published on December 7, 2012

Nuclear Cloning, Epigenetic Reprogramming and Cellular Differentiation

Nuclear cloning and epigenetic reprogramming of the genome

scientific article

Nuclear cloning of embryonal carcinoma cells

scholarly article

Nuclear cloning, embryonic stem cells, and transplantation therapy.

scientific article

Nuclear cloning, epigenetic reprogramming and cellular differentiation.

scientific article

Nuclear cloning, epigenetic reprogramming, and cellular differentiation

scientific article

Nuclear reprogramming and pluripotency

scientific article

Nuclear transplantation, embryonic stem cells and the potential for cell therapy

scientific article published on January 2004

Nuclear transplantation, embryonic stem cells, and the potential for cell therapy

scientific article

Nuclear transplantation: lessons from frogs and mice

scientific article

OCT4 cooperates with distinct ATP-dependent chromatin remodelers in naïve and primed pluripotent states in human

scientific article

Oct4 expression is not required for mouse somatic stem cell self-renewal

scientific article

On the cloning of animals from terminally differentiated cells

scientific article published on 01 February 2007

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering ⬇️

scientific article (publication date: 9 May 2013)

One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

scientific article published on 29 August 2013

One-step generation of monoclonal B cell receptor mice capable of isotype switching and somatic hypermutation.

scientific article

Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis

scientific article

Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming

scientific article published on 31 January 2019

Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming

scientific article published on 01 March 2019

Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells

scientific article

Parent-of-Origin DNA Methylation Dynamics during Mouse Development

scientific article published on September 2016

Parental origin-specific expression of Mash2 is established at the time of implantation with its imprinting mechanism highly resistant to genome-wide demethylation

scientific article published in September 1999

Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors

scientific article (publication date: 6 March 2009)

Parkinson-associated risk variant in distal enhancer of α-synuclein modulates target gene expression

scientific article

Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation

scientific article published on 16 June 2015

Partial FMRP expression is sufficient to normalize neuronal hyperactivity in Fragile X neurons

scientific article published on 26 December 2019

Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2.

scholarly article

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

scientific article

Passive immunotherapy prevents expression of endogenous Moloney virus and amplification of proviral DNA in BALB/Mo mice ⬇️

scientific article published on June 1, 1980

Pharmacological enhancement of KCC2 gene expression exerts therapeutic effects on human Rett syndrome neurons and Mecp2 mutant mice

scientific article published on 01 July 2019

Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function.

scientific article

Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues

scientific article

Pluripotent stem cells are highly susceptible targets for syngeneic, allogeneic, and xenogeneic natural killer cells

scientific article

Politically correct human embryonic stem cells?

scientific article published on 01 March 2006

Polycomb complexes repress developmental regulators in murine embryonic stem cells

scientific article (publication date: 18 May 2006)

Position-dependent silencing of germline Vß segments on TCRß alleles containing preassembled VßDJßCß1 genes

scientific article

Postnatal loss of methyl-CpG binding protein 2 in the forebrain is sufficient to mediate behavioral aspects of Rett syndrome in mice

scientific journal article

Prenatal and postnatal requirements of NT-3 for sympathetic neuroblast survival and innervation of specific targets

scientific article published in February 1996

Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening

scientific article

Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation

scientific article published on February 2008

Provirus integration into a gene encoding a ubiquitin-conjugating enzyme results in a placental defect and embryonic lethality

scientific article published on October 1996

Rapid generation of inducible mouse mutants

scientific article

Recombination signatures distinguish embryonic stem cells derived by parthenogenesis and somatic cell nuclear transfer

scientific article

Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett syndrome

scientific article

Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis

scientific article

Reduction in the number of spinal motor neurons in neurotrophin-3-deficient mice

scientific article published on 01 November 1995

Regulation of ES cell differentiation by functional and conformational modulation of p53.

scientific article published on October 1997

Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice.

scientific article

Reprogramming efficiency following somatic cell nuclear transfer is influenced by the differentiation and methylation state of the donor nucleus

scientific article

Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells

scientific article

Reprogramming of a melanoma genome by nuclear transplantation

scientific article published on August 2004

Reprogramming of human peripheral blood cells to induced pluripotent stem cells

scientific article

Reprogramming of murine and human somatic cells using a single polycistronic vector

scholarly article

Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.

scientific article published on 15 May 2009

Reprogramming of neural progenitor cells into induced pluripotent stem cells in the absence of exogenous Sox2 expression

scientific article

Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors

scientific article

Reprogramming of somatic cell identity

scientific article

Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene.

scientific article

Rescue of type I collagen-deficient phenotype by retroviral-vector-mediated transfer of human pro alpha 1(I) collagen gene into Mov-13 cells

scientific article published on August 1987

Restarting stalled autophagy a potential therapeutic approach for the lipid storage disorder, Niemann-Pick type C1 disease.

scientific article published on June 2014

Retroviral expression in embryonic stem cells and hematopoietic stem cells

scientific article

Retrovirus activation in embryonal carcinoma cells by cellular promoters

scientific article published in December 1989

Retrovirus genomes methylated by mammalian but not bacterial methylase are non-infectious

scientific article published in Nature

Retrovirus insertion inactivates mouse alpha 1(I) collagen gene by blocking initiation of transcription

scientific article published in March 1986

Retrovirus integration and chromatin structure: Moloney murine leukemia proviral integration sites map near DNase I-hypersensitive sites

scientific article published on February 1987

Retrovirus-induced de novo methylation of flanking host sequences correlates with gene inactivity

scientific article

Retrovirus-induced insertional mutagenesis: mechanism of collagen mutation in Mov13 mice

scientific article published on October 1991

Retrovirus-induced insertional mutation in Mov13 mice affects collagen I expression in a tissue-specific manner

scientific article published on 01 June 1989

Retrovirus-induced lethal mutation in collagen I gene of mice is associated with an altered chromatin structure

scientific article

Retroviruses and Embryogenesis: De Novo Methylation Activity Involved in Gene Expression

article

Retroviruses and insertional mutagenesis

scientific article published on 01 January 1985

Retroviruses and insertional mutagenesis in mice: proviral integration at the Mov 34 locus leads to early embryonic death

scientific article published on 01 June 1987

Retroviruses as probes for mammalian development: allocation of cells to the somatic and germ cell lineages.

scientific article published in July 1986

Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues ⬇️

journal article from 'Proceedings of the National Academy of Sciences' published in 2021

Role for DNA methylation in genomic imprinting

scientific article (publication date: 25 November 1993)

Role of the Xist Gene in X Chromosome Choosing ⬇️

scientific article published on March 6, 1998

S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson's Disease Models

scientific article published in November 2017

SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome

scientific article published on 13 December 2020

SCNT-derived ESCs with mismatched mitochondria trigger an immune response in allogeneic hosts

scientific article published on 20 November 2014

SMARCE1 is required for the invasive progression of in situ cancers

scientific article

SOX2 co-occupies distal enhancer elements with distinct POU factors in ESCs and NPCs to specify cell state

scientific article

Sensory but not motor neuron deficits in mice lacking NT4 and BDNF

scientific article published in Nature

Sequence-specific methylation of the mouse H19 gene in embryonic cells deficient in the Dnmt-1 gene

scientific article published in January 1998

Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells

scientific article

Serrate2 is disrupted in the mouse limb-development mutant syndactylism ⬇️

scientific article published on October 16, 1997

Severe deficits in 5-HT2A -mediated neurotransmission in BDNF conditional mutant mice

scientific article published in March 2006

Severe peripheral sensory neuron loss and modest motor neuron reduction in mice with combined deficiency of brain-derived neurotrophic factor, neurotrophin 3 and neurotrophin 4/5.

scientific article published on May 2000

Simplified mammalian DNA isolation procedure

scientific article (publication date: 11 August 1991)

Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase ⬇️

scientific article published on September 14, 2012

Single-cell analysis reveals that expression of nanog is biallelic and equally variable as that of other pluripotency factors in mouse ESCs

scientific article

Single-gene transgenic mouse strains for reprogramming adult somatic cells

scientific article

Sixteenth Annual Pezcoller Symposium: stem cells and epigenesis in cancer

scientific article published in November 2004

Skin graft rejection by beta 2-microglobulin-deficient mice ⬇️

scientific article published on April 1, 1992

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics

scientific article published on 20 July 2015

Somatic cell nuclear transfer and derivation of embryonic stem cells in the mouse

scientific article published on 02 June 2008

Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis

scientific article published on March 2007

Stem Cell Research: Promise and Progress

scientific article published on June 2015

Stem Cells, Genome Editing, and the Path to Translational Medicine

scientific article published on 01 October 2018

Stem cells and interspecies chimaeras

scientific article published on December 2016

Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming

scientific article (publication date: 22 February 2008)

Stem cells. Setting standards for human embryonic stem cells

scientific article

Stroke Damage in Mice after Knocking the Neutrophin-4 Gene into the Brain-Derived Neurotrophic Factor Locus

article

Stroke damage in mice after knocking the neutrophin-4 gene into the brain-derived neurotrophic factor locus

scientific article published in February 2003

Structure and chromosomal mapping of a highly polymorphic repetitive DNA sequence from the pseudoautosomal region of the mouse sex chromosomes

scientific article published on 01 January 1990

Studies on the physiological role of brain-derived neurotrophic factor and neurotrophin-3 in knockout mice.

scientific article

Suppressed epileptogenesis in BDNF mutant mice

scientific article published on 01 June 1995

Suppression of intestinal neoplasia by DNA hypomethylation.

scientific article

Suppression of intestinal neoplasia by deletion of Dnmt3b

scientific article

Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions

scientific article published on 7 November 2011

Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation

scientific article

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

scientific article published on 22 August 2014

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency.

scientific article

Systematic identification of culture conditions for induction and maintenance of naive human pluripotency

scientific article

T-cell receptor-driven lymphomagenesis in mice derived from a reprogrammed T cell ⬇️

scientific article published on October 18, 2010

TALEN-mediated editing of the mouse Y chromosome

scientific article published on 12 May 2013

TCR beta feedback signals inhibit the coupling of recombinationally accessible V beta 14 segments with DJ beta complexes

scientific article

TET1 is a tumor suppressor of hematopoietic malignancy

scientific article

TET1 plays an essential oncogenic role in MLL-rearranged leukemia

scientific article published on July 2013

TGF-β-induced epigenetic deregulation of SOCS3 facilitates STAT3 signaling to promote fibrosis

scientific article published on 06 April 2020

Target derived and putative local actions of neurotrophins in the peripheral nervous system.

scientific article published on January 1994

Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters

scientific article

Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death

scientific article published in October 1992

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality ⬇️

scientific article (publication date: 12 June 1992)

Technical challenges in using human induced pluripotent stem cells to model disease

scientific article published on December 2009

Tet1 Is Dispensable for Maintaining Pluripotency and Its Loss Is Compatible with Embryonic and Postnatal Development ⬇️

scientific article published on August 5, 2011

Tet1 and Tet2 Protect DNA Methylation Canyons against Hypermethylation

scientific article

Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors

scientific article published on 11 January 2017

Tet1 is critical for neuronal activity-regulated gene expression and memory extinction

scientific article

The (epi)genetic control of mammalian X-chromosome inactivation

scientific article published on April 1997

The developmental potential of iPSCs is greatly influenced by reprogramming factor selection

scientific article

The disease progression of Mecp2 mutant mice is affected by the level of BDNF expression

scientific article published in February 2006

The integration sites of endogenous and exogenous Moloney murine leukemia virus ⬇️

scientific article published on September 1, 1979

The pluripotency regulator Oct4: a role in somatic stem cells?

scientific article

The putative Drosophila methyltransferase gene dDnmt2 is contained in a transposon-like element and is expressed specifically in ovaries

scientific article published on July 2000

The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system

scientific article published on January 1991

The role of DNA methylation in cancer genetic and epigenetics

scientific article

The study of collagen structure and function by site-directed mutagenesis of collagen genes

scientific article published on 01 January 1990

Tissue-specific and ectopic expression of genes introduced into transgenic mice by retroviruses

scientific article

Toward eliminating HLA class I expression to generate universal cells from allogeneic donors

scientific article published on 05 June 2013

Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation

scientific article

Tracing dynamic changes of DNA methylation at single-cell resolution

scientific article

Transcription of cloned Moloney murine leukemia proviral DNA injected into Xenopus laevis oocytes ⬇️

scientific article published on June 25, 1983

Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain

scientific article

Transcriptional profiling of cells sorted by RNA abundance

scientific article

Transdifferentiation by defined factors as a powerful research tool to address basic biological questions

scientific article published on 19 November 2012

Transgene excision has no impact on in vivo integration of human iPS derived neural precursors

scientific article

Transgenic mice with defined combinations of drug-inducible reprogramming factors

scientific article published on 18 January 2009

Transnuclear TRP1-specific CD8 T cells with high or low affinity TCRs show equivalent antitumor activity

scientific article published on August 2013

Transnuclear mice with pre-defined T cell receptor specificities against Toxoplasma gondii obtained via SCNT.

scientific article

Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT.

scientific article

Treatment of mice with 5-azacytidine efficiently activates silent retroviral genomes in different tissues

scientific article published on March 1985

Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin

scientific article

Trisomy eight in ES cells is a common potential problem in gene targeting and interferes with germ line transmission

scientific article published on May 1997

Two distinct sequence elements mediate retroviral gene expression in embryonal carcinoma cells

scientific article published on September 1987

Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch

scientific article

Utility of C57BL/6J × 129/SvJae embryonic stem cells for generating chromosomal deletions: tolerance to γ radiation and microsatellite polymorphism ⬇️

scientific article published on March 1, 1998

V(D)J recombination is not activated by demethylation of the kappa locus

scientific article published on July 2000

Virus-specific transcription and translation in organs of BALB/Mo mice: comparative study using quantitative hybridization, in situ hybridization, and immunocytochemistry

scientific article

Whole chromosome loss and genomic instability in mouse embryos after CRISPR-Cas9 genome editing

scientific article published on 06 October 2021

Whsc1 links pluripotency exit with mesendoderm specification

scientific article published on 24 June 2019

Wnt signaling promotes reprogramming of somatic cells to pluripotency

scientific article (publication date: 7 August 2008)

Wt1 functions in the development of germ cells in addition to somatic cell lineages of the testis

scientific journal article

X Chromosome Inactivation Is Mediated by Xist RNA Stabilization ⬇️

scientific article published on September 5, 1997

X chromosome choice occurs independently of asynchronous replication timing

scientific article

X chromosome-linked transmission and expression of retroviral genomes microinjected into mouse zygotes

scientific article

X-Chromosome inactivation in cloned mouse embryos

scientific article

X-chromosome inactivation during spermatogenesis is regulated by an Xist/Tsix-independent mechanism in the mouse

scientific article published on 01 December 2002

X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner

scientific article

YAP1 increases organ size and expands undifferentiated progenitor cells

scientific journal article

YY1 Is a Structural Regulator of Enhancer-Promoter Loops

scientific article published on 30 November 2017

c-Myc is dispensable for direct reprogramming of mouse fibroblasts.

scientific article

p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF ⬇️

scientific article published on 01 April 1994

p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins

scientific article published on 01 October 1993

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