List of works - Thomas D. Hurley

A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells

scientific article published on 01 March 2019

A highly prevalent equine glycogen storage disease is explained by constitutive activation of a mutant glycogen synthase

scientific article published on 31 August 2016

A new crystal form of mouse thiamin pyrophosphokinase ⬇️

scientific article published on January 1, 2011

ALDH1 Bio-activates Nifuroxazide to Eradicate ALDH Melanoma-Initiating Cells

scientific article published on 04 October 2018

Cimetidine Inhibition of Human Gastric and Liver Alcohol Dehydrogenase Isoenzymes: Identification of Inhibitor Complexes by Kinetics and Molecular Modeling ⬇️

scientific article published on March 28, 1995

Crystallization and preliminary X-ray investigation of bovine liver mitochondrial aldehyde dehydrogenase

scientific article published on October 20, 1992

Crystallographic studies of casein kinase I δ: toward a structural understanding of auto-inhibition ⬇️

scientific article published on 01 May 1998

Development of Selective Inhibitors for Aldehyde Dehydrogenases Based on Substituted Indole-2,3-diones

scientific article

Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase

scientific article published on 23 March 2020

Discovery of novel regulators of aldehyde dehydrogenase isoenzymes ⬇️

scientific article published on February 22, 2011

Genes encoding enzymes involved in ethanol metabolism ⬇️

scientific article published on January 1, 2012

Glycogen and its metabolism: some new developments and old themes ⬇️

scientific article published on February 1, 2012

Impaired malin expression and interaction with partner proteins in Lafora disease

scientific article published in 2024

Incorporation of phosphate into glycogen by glycogen synthase

scientific article published on 29 March 2016

Inhibition of the Aldehyde Dehydrogenase 1/2 Family by Psoralen and Coumarin Derivatives

scientific article published on 20 February 2017

Multiple Glycogen-binding Sites in Eukaryotic Glycogen Synthase Are Required for High Catalytic Efficiency toward Glycogen ⬇️

scientific article published on August 11, 2011

N,N-diethylaminobenzaldehyde (DEAB) as a substrate and mechanism-based inhibitor for human ALDH isoenzymes

scientific article published on 12 December 2014

Phosphate Incorporation during Glycogen Synthesis and Lafora Disease ⬇️

scientific article published on March 2, 2011

Structural basis for glucose-6-phosphate activation of glycogen synthase ⬇️

scientific article published on September 27, 2010

Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy

scientific article published on 28 September 2018

Studies on the regulation of the mitochondrial α-ketoacid dehydrogenase complexes and their kinases ⬇️

scientific article published on January 1, 1997

Targeting Aldehyde Dehydrogenases to Eliminate Cancer Stem Cells in Gynecologic Malignancies

scientific article published on 13 April 2020

The 5th International Lafora Epilepsy Workshop: Basic science elucidating therapeutic options and preparing for therapies in the clinic

scientific article published on 10 January 2020

The Potential Roles of the Conserved Amino Acids in Human Liver Mitochondrial Aldehyde Dehydrogenase ⬇️

scientific article published on July 25, 1997

Tryptophan fluorescence quenching by alkaline pH and ternary complex formation in human beta 1 beta 1 and horse EE alcohol dehydrogenases

scientific article published on April 6, 1992

List of works by Thomas D. Hurley