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List of works by Karen Aboody

A preclinical evaluation of neural stem cell-based cell carrier for targeted antiglioma oncolytic virotherapy

scientific article published on July 2013

ACTR-22. A PHASE I STUDY OF CYTOSINE DEAMINASE-EXPRESSING NEURAL STEM CELLS (CD-NSCs) ADMINISTERED INTRACRANIALLY AND IN COMBINATION WITH ORAL 5-FLUOROCYTOSINE (5-FC) AND LEUCOVORIN IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMA

ACTR-36. A PHASE I STUDY OF NEURAL STEM CELLS LOADED WITH AN ONCOLYTIC ADENOVIRUS FOR PATIENTS WITH NEWLY DIAGNOSED MALIGNANT GLIOMA: PRELIMINARY SAFETY AND DATA ANALYSIS

scientific article published on 6 November 2017

ATPS-29INTRANASAL DELIVERY OF THERAPEUTIC NEURAL STEM CELLS TO TARGET INTRACEREBRAL GLIOMA.

scientific article published on 9 November 2015

BMET-40NANO PLATFORM FOR DYNAMIC IN VIVO TRACKING OF NEURAL STEM CELLS TO BRAIN METASTASES OF BREAST CANCER.

scientific article

Brain tumor tropism of transplanted human neural stem cells is induced by vascular endothelial growth factor.

scientific article published on June 2005

Cell-Mediated Enzyme Prodrug Cancer Therapies

scientific article published on 12 September 2017

Cellular Host Responses to Gliomas

scientific article published on April 23, 2012

Chlorotoxin-directed CAR T cells for specific and effective targeting of glioblastoma

scientific article published on 01 March 2020

Concise Review: Neural Stem Cell-Mediated Targeted Cancer Therapies

article

Concise review: stem cells as an emerging platform for antibody therapy of cancer

scientific article

Conjugation of pH-responsive nanoparticles to neural stem cells improves intratumoral therapy

scientific article

Contact and encirclement of glioma cells in vitro is an intrinsic behavior of a clonal human neural stem cell line

scientific article

Controlled Payload Release by Magnetic Field Triggered Neural Stem Cell Destruction for Malignant Glioma Treatment

scientific article

Developing Implantable Scaffolds to Enhance Neural Stem Cell Therapy for Post-Operative Glioblastoma

scientific article published on 13 February 2020

Development of a tumor-selective approach to treat metastatic cancer

scientific article published on 20 December 2006

Dynamic In Vivo SPECT Imaging of Neural Stem Cells Functionalized with Radiolabeled Nanoparticles for Tracking of Glioblastoma

scientific article published on 12 November 2015

ET-05INTRANASAL DELIVERY OF NEURAL STEM CELLS LOADED WITH ONCOLYTIC ADENOVIRUS EXTENDS SURVIVAL OF MICE WITH INTRACRANIAL GLIOMA.

scientific article published in November 2014

EXTH-49. ANALYSES OF LONG-TERM STABILITY AND DISTRIBUTION PATTERNS OF L-MYC IMMORTALIZED HUMAN NEURAL STEM CELLS

scientific article published on 6 November 2017

Early Changes in Tumor Perfusion from T1-Weighted Dynamic Contrast-Enhanced MRI following Neural Stem Cell-Mediated Therapy of Recurrent High-Grade Glioma Correlate with Overall Survival

scientific article published on 14 March 2018

Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer

Erratum: Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer

scientific article published on 11 June 2020

Feasibility of intracerebrally administering multiple doses of genetically modified neural stem cells to locally produce chemotherapy in glioma patients

scientific article published on 08 September 2020

GMP Production and Scale-Up of Adherent Neural Stem Cells with a Quantum Cell Expansion System.

scientific article published on 7 July 2018

Genetically engineered human neural stem cells with rabbit carboxyl esterase can target brain metastasis from breast cancer

scientific article published on 14 July 2011

Glioma-produced extracellular matrix influences brain tumor tropism of human neural stem cells.

scientific article published on 6 April 2006

Gold nanoparticle-loaded neural stem cells for photothermal ablation of cancer.

scientific article published on 17 April 2013

Gold nanorod-mediated near-infrared laser ablation: in vivo experiments on mice and theoretical analysis at different settings.

scientific article

Human Neural Stem Cell Biodistribution and Predicted Tumor Coverage by a Diffusible Therapeutic in a Mouse Glioma Model

scientific article

Human neural stem cell tropism to metastatic breast cancer.

scientific article

Human neural stem cells target experimental intracranial medulloblastoma and deliver a therapeutic gene leading to tumor regression

scientific article published on September 2006

Increased Expression of System xc- in Glioblastoma Confers an Altered Metabolic State and Temozolomide Resistance

scientific article published on 22 September 2016

Intranasal Oncolytic Virotherapy with CXCR4-Enhanced Stem Cells Extends Survival in Mouse Model of Glioma

scientific article published on 29 August 2016

Intranasal delivery of mesenchymal stem cells significantly extends survival of irradiated mice with experimental brain tumors

scientific article

Intraperitoneal Administration of Neural Stem Cell-Nanoparticle Conjugates Targets Chemotherapy to Ovarian Tumors.

scientific article

Intravascular administration of tumor tropic neural progenitor cells permits targeted delivery of interferon-beta and restricts tumor growth in a murine model of disseminated neuroblastoma

scientific article

Intravascular delivery of neural stem cell lines to target intracranial and extracranial tumors of neural and non-neural origin.

scientific article

Iron labeling and pre-clinical MRI visualization of therapeutic human neural stem cells in a murine glioma model

scientific article

L-MYC Expression Maintains Self-Renewal and Prolongs Multipotency of Primary Human Neural Stem Cells

scientific article published on 17 August 2016

Long-term stability and computational analysis of migration patterns of L-MYC immortalized neural stem cells in the brain

scientific article published in PLoS ONE

MMP14 as a novel downstream target of VEGFR2 in migratory glioma-tropic neural stem cells

scientific article

Magnetic resonance imaging tracking of ferumoxytol-labeled human neural stem cells: studies leading to clinical use.

scientific article published on 06 September 2013

NIMG-57. SURVIVAL ANALYSIS OF GLIOBLASTOMA (GBM) PATIENTS RECEIVING NEURAL STEM CELL (NSC)-MEDIATED TREATMENT USING T1-WEIGHTED DYNAMIC CONTRAST ENHANCED (DCE) MRI

Nanoparticle‐Programmed Self‐Destructive Neural Stem Cells for Glioblastoma Targeting and Therapy

scientific article published on July 21, 2013

Neural Stem Cell-Based Anticancer Gene Therapy: A First-in-Human Study in Recurrent High-Grade Glioma Patients.

scientific article published on 15 December 2016

Neural Stem Cells Improve the Delivery of Oncolytic Chimeric Orthopoxvirus in a Metastatic Ovarian Cancer Model

scientific article published on 06 July 2020

Neural Stem Cells Secreting Anti-HER2 Antibody Improve Survival in a Preclinical Model of HER2 Overexpressing Breast Cancer Brain Metastases.

scientific article

Neural Stem Cell–Mediated Enzyme/Prodrug Therapy for Glioma: Preclinical Studies

scientific article published on May 8, 2013

Neural progenitor cell-mediated delivery of interferon beta improves neuroblastoma response to cyclophosphamide

scientific article published on 23 August 2008

Neural progenitor cell-mediated delivery of osteoprotegerin limits disease progression in a preclinical model of neuroblastoma bone metastasis

scientific article published on January 2009

Neural stem cell biology may be well suited for improving brain tumor therapies.

scientific article

Neural stem cell targeting of glioma is dependent on phosphoinositide 3-kinase signaling

scientific article

Neural stem cell tropism to glioma: critical role of tumor hypoxia.

scientific article

Neural stem cell-based cell carriers enhance therapeutic efficacy of an oncolytic adenovirus in an orthotopic mouse model of human glioblastoma.

scientific article

Neural stem cell-mediated delivery of irinotecan-activating carboxylesterases to glioma: implications for clinical use.

scientific article published on 28 October 2013

Neural stem cell-mediated intratumoral delivery of gold nanorods improves photothermal therapy.

scientific article

Neural stem cells as a novel platform for tumor-specific delivery of therapeutic antibodies

scientific article

Neural stem cells improve intracranial nanoparticle retention and tumor-selective distribution.

scientific article published on February 2014

Novel Chimeric Poxvirus CF17 Improves Survival in a Murine Model of Intraperitoneal Ovarian Cancer Metastasis

scientific article published on 10 October 2020

Novel method for visualizing and modeling the spatial distribution of neural stem cells within intracranial glioma

scientific article published on 13 May 2007

Opinion: the origin of the cancer stem cell: current controversies and new insights

scientific article published on 01 November 2005

Optimization of a Neural Stem-Cell-Mediated Carboxylesterase/Irinotecan Gene Therapy for Metastatic Neuroblastoma

scientific article published on 14 December 2016

Overexpression Improves Survival and Efficacy of Neural Stem Cell-Mediated Enzyme Prodrug Therapy

scientific article published on 20 June 2018

Planarians as a model of aging to study the interaction between stem cells and senescent cells in vivo

scientific article

Quantitative Evaluation of Intraventricular Delivery of Therapeutic Neural Stem Cells to Orthotopic Glioma

scientific article published on 19 February 2019

Researchers and the translational reality. Interview with Karen Aboody

scientific article

SC-03NEURAL STEM CELL-MEDIATED ENZYME/PRODRUG THERAPY FOR MEDULLOBLASTOMA.

scientific article published on 21 April 2015

SLC7A11 Overexpression in Glioblastoma Is Associated with Increased Cancer Stem Cell-Like Properties

scientific article published on 13 June 2017

STEM-01NEURAL STEM CELL-MEDIATED ENZYME/PRODRUG THERAPY FOR NEUROBLASTOMA: TRANSLATION TO THE CLINIC.

scientific article

STEM-10L-myc EXPRESSION PROMOTES HUMAN NEURAL STEM CELL MULTIPOTENCY.

scientific article

STEM-32. PRE-CLINICAL SAFETY AND EFFICACY STUDIES OF NEURAL STEM CELL MEDIATED CARBOXYLESTERASE/IRINOTECAN ENZYME/PRODRUG GENE THERAPY FOR RECURRENT GLIOMA LEADING TO FIRST-IN-HUMAN PHASE I CLINICAL TRIAL

STEM-37. GENETIC EDITING OF NEURAL STEM CELLS FOR INTRANASAL THERAPEUTIC DELIVERY TO MALIGNANT BRAIN TUMORS

Selective antitumor effect of neural stem cells expressing cytosine deaminase and interferon-beta against ductal breast cancer cells in cellular and xenograft models

scientific article published on October 2013

Silica Coated Paclitaxel Nanocrystals Enable Neural Stem Cell Loading For Treatment of Ovarian Cancer

scientific article published on 12 April 2019

Single dose GLP toxicity and biodistribution study of a conditionally replicative adenovirus vector, CRAd-S-pk7, administered by intracerebral injection to Syrian hamsters

scientific article published on 16 May 2016

Specific targeting of ovarian tumor-associated macrophages by large, anionic nanoparticles

scientific article published on 30 July 2020

Strategies for enhancing antibody delivery to the brain

scientific article published on 08 July 2011

TWIST1 associates with NF-κB subunit RELA via carboxyl-terminal WR domain to promote cell autonomous invasion through IL8 production

scientific article published on August 14, 2012

Targeting of melanoma brain metastases using engineered neural stem/progenitor cells

scientific article published on 8 March 2006

The Timing of Neural Stem Cell-Based Virotherapy Is Critical for Optimal Therapeutic Efficacy When Applied With Radiation and Chemotherapy for the Treatment of Glioblastoma

scientific article published on 07 August 2013

The histone demethylase jumonji coordinates cellular senescence including secretion of neural stem cell-attracting cytokines

scientific article published on 4 February 2015

Therapeutic targeting of melanoma cells using neural stem cells expressing carboxylesterase, a CPT-11 activating enzyme

scientific article

Translating Stem Cell Studies to the Clinic for CNS Repair: Current State of the Art and the Need for a Rosetta Stone

scientific article published on May 26, 2011

Tumor-derived chemokine MCP-1/CCL2 is sufficient for mediating tumor tropism of adoptively transferred T cells.

scientific article published on September 2007

Tumor-targeted enzyme/prodrug therapy mediates long-term disease-free survival of mice bearing disseminated neuroblastoma

scientific article published on January 2007

Urokinase plasminogen activator and urokinase plasminogen activator receptor mediate human stem cell tropism to malignant solid tumors

scientific article

Vascular endothelial growth factor A contributes to glioma-induced migration of human marrow stromal cells (hMSC).

scientific article published on 29 March 2006

Vascular endothelial growth factor-stimulated cerebral microvascular endothelial cells mediate the recruitment of neural stem cells to the neurovascular niche

scientific article published on 10 March 2009