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List of works by Zalfa A. Abdel-Malek

Agouti signal protein: crossing the 'yellow' signal and arriving to pathways that affect tumorgenesis

scientific article published on 11 March 2009

Alpha-Melanocyte–Stimulating Hormone Suppresses Oxidative Stress through a p53-Mediated Signaling Pathway in Human Melanocytes ⬇️

scientific article published on May 23, 2012

Beyond Red Hair and Sunburns: Uncovering the Molecular Mechanisms of MC1R Signaling and Repair of UV-Induced DNA Damage

scientific article published on December 2015

Chemoprevention agents for melanoma: a path forward into phase 3 clinical trials

scientific article published on 03 October 2018

Cutaneous photobiology. The melanocyte vs. the sun: who will win the final round?

scientific article

Cutaneous photoprotection and melanoma susceptibility: reaching beyond melanin content to the frontiers of DNA repair

scientific article

Dark CPDs and photocarcinogenesis: the party continues after the lights go out

scientific article published on 01 July 2015

Defining MC1R regulation in human melanocytes by its agonist α-melanocortin and antagonists agouti signaling protein and β-defensin 3.

scientific article published on 10 May 2012

Development of α-Melanocortin Analogs for Melanoma Prevention and Targeting ⬇️

scientific article published on 01 January 2010

Diversity of pigmentation in cultured human melanocytes is due to differences in the type as well as quantity of melanin

scientific article published on 01 April 2006

Endothelin-1 and α-melanocortin have redundant effects on global genome repair in UV-irradiated human melanocytes despite distinct signaling pathways

scientific article published on 04 October 2019

Endothelin-1 protects human melanocytes from UV-induced DNA damage by activating JNK and p38 signalling pathways.

scientific article published in April 2015

Estela Medrano, 1943-2010.

scientific article published in December 2010

Fueling Melanocytes with ATP from Keratinocytes Accelerates Melanin Synthesis

scientific article published on 01 July 2019

Human melanocortin 1 receptor variants, receptor function and melanocyte response to UV radiation.

scientific article published in June 2002

In vitro behavior and UV response of melanocytes derived from carriers of CDKN2A mutations and MC1R variants

scientific article published on 05 September 2018

Influence of alpha-melanocyte-stimulating hormone and ultraviolet radiation on the transfer of melanosomes to keratinocytes

scientific article

Joseph Thomas Bagnara (1929–2016), a pioneer of Pigment Cell Biology par excellence

obituary published in 2017

Light or Dark Pigmentation of Engineered Skin Substitutes Containing Melanocytes Protects against Ultraviolet Light-Induced DNA Damage In Vivo

scientific article published on 13 February 2020

MC1R and the response of melanocytes to ultraviolet radiation

scientific article

MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation

scientific article published on 30 May 2014

MC1R: Front and Center in the Bright Side of Dark Eumelanin and DNA Repair

scholarly article by Viki B Swope published in September 2018

Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human melanocytes

scientific article

Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation.

scientific article published on 2 June 2010

Melanocortins and the melanocortin 1 receptor, moving translationally towards melanoma prevention

scientific article published on 11 July 2014

Melanocytes as instigators and victims of oxidative stress

scientific article

Melanoma prevention strategy based on using tetrapeptide alpha-MSH analogs that protect human melanocytes from UV-induced DNA damage and cytotoxicity

scientific article published on 24 May 2006

Mesenchymal-epithelial interactions in the skin: increased expression of dickkopf1 by palmoplantar fibroblasts inhibits melanocyte growth and differentiation

scientific article

Mitogen- and ultraviolet-B-induced signaling pathways in normal human melanocytes

scientific article published in February 2002

N-terminal fatty acylated His-dPhe-Arg-Trp-NH(2) tetrapeptides: influence of fatty acid chain length on potency and selectivity at the mouse melanocortin receptors and human melanocytes

scientific article published in May 2005

PGE(2) is a UVR-inducible autocrine factor for human melanocytes that stimulates tyrosinase activation

scientific article published on 25 May 2010

Proceeding Report of the Second Vitiligo International Symposium-November 9-10, 2018, Detroit, Michigan, USA

scientific article published on 27 January 2020

Regulation of constitutive and UVR-induced skin pigmentation by melanocortin 1 receptor isoforms.

scientific article published on 28 July 2006

Regulation of the human melanocortin 1 receptor expression in epidermal melanocytes by paracrine and endocrine factors and by ultraviolet radiation

scientific article published in December 2002

Restoration of cutaneous pigmentation by transplantation to mice of isogeneic human melanocytes in dermal-epidermal engineered skin substitutes.

scientific article published on 22 June 2017

Semi-rigid tripeptide agonists of melanocortin receptors

scientific article published on 9 July 2009

Signaling from the human melanocortin 1 receptor to ERK1 and ERK2 mitogen-activated protein kinases involves transactivation of cKIT.

scientific article

Significance of the Melanocortin 1 and Endothelin B Receptors in Melanocyte Homeostasis and Prevention of Sun-Induced Genotoxicity

scientific article

Significance of the melanocortin 1 receptor in regulating human melanocyte pigmentation, proliferation, and survival

scientific article (publication date: June 2003)

Significance of the melanocortin 1 receptor in the DNA damage response of human melanocytes to ultraviolet radiation

scientific article

Stepping up melanocytes to the challenge of UV exposure

scientific article

Suppression of MAPK signaling in BRAF-activated PTEN-deficient melanoma by blocking β-catenin signaling in cancer-associated fibroblasts

scientific article

The enigma and challenges of vitiligo pathophysiology and treatment

scientific article published on 21 March 2020

The potential role of antioxidants in mitigating skin hyperpigmentation resulting from ultraviolet and visible light-induced oxidative stress

scientific article published on 15 October 2018

Walking in the footsteps of giants: melanocortins and human pigmentation, a historical perspective

scientific article published in June 2007

alpha-MSH activates immediate defense responses to UV-induced oxidative stress in human melanocytes

scientific article published on 29 July 2009

alpha-MSH tripeptide analogs activate the melanocortin 1 receptor and reduce UV-induced DNA damage in human melanocytes

scientific article

alpha-Melanocortin and endothelin-1 activate antiapoptotic pathways and reduce DNA damage in human melanocytes

scientific article published on 01 May 2005

beta-Defensin 3: a novel and unexpected key that unlocks the melanocortin 1 receptor

scientific article published in February 2008

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