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List of works by Fábio Klamt

3-O-Methylquercetin from Achyrocline satureioides-cytotoxic activity against A375-derived human melanoma cell lines and its incorporation into cyclodextrins-hydrogels for topical administration

scientific article published on 06 January 2021

A systematic review of human antioxidant genes.

scientific article published on January 2009

Achyrocline satureioides compounds, achyrobichalcone and 3-O-methylquercetin, induce mitochondrial dysfunction and apoptosis in human breast cancer cell lines

scientific article published on 25 July 2020

Activated peripheral blood mononuclear cell mediators trigger astrocyte reactivity

scientific article published on 05 June 2019

Acute treatment with diphenyl diselenide inhibits glutamate uptake into rat hippocampal slices and modifies glutamate transporters, SNAP-25, and GFAP immunocontent.

scientific article published on 18 November 2009

All-trans retinoic acid induces free radical generation and modulate antioxidant enzyme activities in rat sertoli cells

scientific article published on 15 February 2006

Antioxidant defense capacity of ovarian tissue after vitrification in a metal closed system

Antioxidant treatment reverses mitochondrial dysfunction in a sepsis animal model.

scientific article

Bioinformatics approach for the validation of non-small cell lung cancer biomarkers

scientific article published on 01 January 2011

Bioinformatics approach to evaluate differential gene expression of M1/M2 macrophage phenotypes and antioxidant genes in atherosclerosis.

scientific article published in November 2014

Brazilian marine sponge Polymastia janeirensis induces apoptotic cell death in human U138MG glioma cell line, but not in a normal cell culture

scientific article

CFL1 expression levels as a prognostic and drug resistance marker in nonsmall cell lung cancer

scientific article

Can electrons travel through actin microfilaments and generate oxidative stress in retinol treated Sertoli cell?

scientific article published on 03 January 2007

Cannabidiol Exposure During Neuronal Differentiation Sensitizes Cells Against Redox-Active Neurotoxins

scientific article

Cannabinoid-Based Therapies and Brain Development: Potential Harmful Effect of Early Modulation of the Endocannabinoid System

scientific article published on 01 August 2018

Cholinergic Differentiation of Human Neuroblastoma SH-SY5Y Cell Line and Its Potential Use as an In vitro Model for Alzheimer's Disease Studies

scientific article published on 29 April 2019

Cofilin-1 levels and intracellular localization are associated with melanoma prognosis in a cohort of patients.

scientific article

Cofilin/actin rod formation by dysregulation of cofilin-1 activity as a central initial step in neurodegeneration

scientific article published on May 2014

Combined Treatments with a Retinoid Receptor Agonist and Epigenetic Modulators in Human Neuroblastoma Cells

scientific article published on 10 November 2016

Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies

scientific article published on 7 April 2010

Convalescent Plasma Therapy on Patients with Severe or Life-Threatening COVID-19: A Metadata Analysis

scientific article published on 10 August 2020

Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells

scientific article published on 26 May 2020

Depression and Mania Induce Pro-inflammatory Activation of Macrophages Following Application of Serum from Individuals with Bipolar Disorder

scientific article published in February 2018

EGR3 Immediate Early Gene and the Brain-Derived Neurotrophic Factor in Bipolar Disorder

scientific article published on 5 February 2018

Enhanced UV-mediated free radical generation; DNA and mitochondrial damage caused by retinol supplementation

scientific article published in August 2003

Eugenia uniflora leaf essential oil promotes mitochondrial dysfunction in Drosophila melanogaster through the inhibition of oxidative phosphorylation

scientific article published on 05 May 2017

Evaluation of the neurotoxic/neuroprotective role of organoselenides using differentiated human neuroblastoma SH-SY5Y cell line challenged with 6-hydroxydopamine

scientific article published on 20 January 2012

Evidence that the major metabolites accumulating in medium-chain acyl-CoA dehydrogenase deficiency disturb mitochondrial energy homeostasis in rat brain

scientific article published on 21 August 2009

Extracts of marine sponge Polymastia janeirensis induce oxidative cell death through a caspase-9 apoptotic pathway in human U138MG glioma cell line

scientific article

Genotoxicity, recombinogenicity and cellular preneoplasic transformation induced by vitamin A supplementation

scientific article published in August 2003

High cofilin-1 levels correlate with cisplatin resistance in lung adenocarcinomas

scientific article published on 10 September 2013

Imbalance in redox status is associated with tumor aggressiveness and poor outcome in lung adenocarcinoma patients

scientific article published on 22 January 2014

Immunosenescence Induced by Plasma from Individuals with Obesity Caused Cell Signaling Dysfunction and Inflammation.

scientific article published on 14 July 2017

Impaired endoplasmic reticulum stress response in bipolar disorder: cellular evidence of illness progression

scientific article

In vitro evaluation of antitumoral efficacy of catalase in combination with traditional chemotherapeutic drugs against human lung adenocarcinoma cells.

scientific article

In vitro optimization of retinoic acid-induced neuritogenesis and TH endogenous expression in human SH-SY5Y neuroblastoma cells by the antioxidant Trolox

scientific article published on 7 July 2011

Increased oxidative damage in carriers of the germline TP53 p.R337H mutation

scientific article

Inhibition of MDR1 expression by retinol treatment increases sensitivity to etoposide (VP16) in human neoplasic cell line

scientific article published on 15 January 2008

Integrated Transcriptomics Establish Macrophage Polarization Signatures and have Potential Applications for Clinical Health and Disease

scientific article published on 25 August 2015

Integrated transcriptomics reveals master regulators of lung adenocarcinoma and novel repositioning of drug candidates

scientific article published on 10 September 2019

Isolation of achyrobichalcone from Achyrocline satureioides by high- speed countercurrent chromatography

scientific article published on 01 January 2015

Lung oxidative response after acute coal dust exposure

scientific article published in November 2004

Master Regulators Connectivity Map: A Transcription Factors-Centered Approach to Drug Repositioning

scientific article published on 02 July 2018

Metabolic rewiring in melanoma drug-resistant cells

scientific article published on 24 May 2020

Metabotropic glutamate receptors as a new therapeutic target for malignant gliomas

scientific article

Methylglyoxal-Induced Protection Response and Toxicity: Role of Glutathione Reductase and Thioredoxin Systems.

scientific article

Mimicking Parkinson's Disease in a Dish: Merits and Pitfalls of the Most Commonly used Dopaminergic In Vitro Models.

scientific article

Modulation of oxidative stress in response to gamma-radiation in human glioma cell lines

scientific article published in January 2003

Morphological and oxidative alterations on Sertoli cells cytoskeleton due to retinol-induced reactive oxygen species

scientific article published in March 2005

Nicotinamide N-methyltransferase catalyses the N-methylation of the endogenous β-carboline norharman: evidence for a novel detoxification pathway.

scientific article published on 7 July 2016

Nicotinamide N-methyltransferase expression in SH-SY5Y human neuroblastoma cells decreases oxidative stress

scientific article published on 07 January 2020

Nicotinamide N-methyltransferase increases complex I activity in SH-SY5Y cells via sirtuin 3.

scientific article published on 8 October 2015

Oxidative parameters and mortality in sepsis induced by cecal ligation and perforation

scientific article published on 29 May 2003

Oxidative stress associates with aggressiveness in lung large-cell carcinoma.

scientific article

Peripheral biomarkers and illness activity in bipolar disorder

scientific article

Peripheral oxidative damage in early-stage mood disorders: a nested population-based case-control study

scientific article published on 19 October 2011

Potential crosstalk between cofilin-1 and EGFR pathways in cisplatin resistance of non-small-cell lung cancer

scientific article published on February 2015

Potential predictive value of cofilin-1 for metastasis occurrence in a small cohort of Argentinian patients with mid-low Breslow thickness melanoma

scientific article published on 08 August 2019

Preventive Physical Training Partially Preserves Heart Function and Improves Cardiac Antioxidant Responses in Rats After Myocardial Infarction Preventive Physical Training and Myocardial Infarction in Rats

scientific article

RA Differentiation Enhances Dopaminergic Features, Changes Redox Parameters, and Increases Dopamine Transporter Dependency in 6-Hydroxydopamine-Induced Neurotoxicity in SH-SY5Y Cells.

scientific article

Redox Biology of Human Cumulus Cells: Basic Concepts, Impact on Oocyte Quality, and Potential Clinical Use

scientific article published on 01 March 2020

Reduced Neurite Density in Neuronal Cell Cultures Exposed to Serum of Patients with Bipolar Disorder

scientific article published on 13 May 2016

Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Reversion or promotion of malignancy by inducing melanogenesis or metastasis

scientific article published on 07 May 2016

Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Upregulation of antioxidant genes correlates with regression of melanoma malignancy and with malignant progression when downregulated

scientific article published on 10 May 2016

Retinol and retinoic acid modulate catalase activity in Sertoli cells by distinct and gene expression-independent mechanisms.

scientific article published on 25 March 2008

Retinol increases catalase activity and protein content by a reactive species-dependent mechanism in Sertoli cells.

scientific article published on 2 May 2008

Retinol induces permeability transition and cytochrome c release from rat liver mitochondria

scientific article

Retinol-induced mdr1 and mdr3 modulation in cultured rat Sertoli cells is attenuated by free radical scavengers

scientific article

Scavenging and antioxidant potential of physiological taurine concentrations against different reactive oxygen/nitrogen species.

scientific article published in January 2010

Sertraline reduces glutamate uptake in human platelets.

scientific article published on 31 October 2015

Simplified low-cost methodology to establish, histologically process and analyze three-dimensional cancer cell spheroid arrays

scientific article published on 10 June 2020

Sulforaphane ameliorates the insulin responsiveness and the lipid profile but does not alter the antioxidant response in diabetic rats.

scientific article

Systemic toxicity in early-stage mood disorders

scientific article published on 08 June 2011

TRF1 as a major contributor for telomeres' shortening in the context of obesity

scientific article published on 27 September 2018

Taurine chloramine decreases cell viability and cytokine production in blood and spleen lymphocytes from septic rats submitted to sepsis

scientific article

The NF kappa B-mediated control of RS and JNK signaling in vitamin A-treated cells: duration of JNK-AP-1 pathway activation may determine cell death or proliferation

scientific article published on 31 December 2008

The kinetic analysis of the N-methylation of 4-phenylpyridine by nicotinamide N-methyltransferase: Evidence for a novel mechanism of substrate inhibition.

scientific article published on 13 March 2018

The pharmacological NFkappaB inhibitors BAY117082 and MG132 induce cell arrest and apoptosis in leukemia cells through ROS-mitochondria pathway activation

scientific article published on 30 July 2009

The potential role of extracellular regulatory kinase in the survival of patients with early stage adenocarcinoma

scientific article

The prognostic impact of tumor-associated macrophages and intra-tumoral apoptosis in non-small cell lung cancer.

scientific article published on 13 August 2013

Time-related increase in mitochondrial superoxide production, biomolecule damage and antioxidant enzyme activities in cortical astrocyte cultures

scientific article published in August 2002

Transcriptomic analysis reveals pH-responsive antioxidant gene networks

scientific article published on June 2012

Validation of cofilin-1 as a biomarker in non-small cell lung cancer: application of quantitative method in a retrospective cohort.

scientific article published on 08 July 2011

Vitamin A supplementation for different periods alters oxidative parameters in lungs of rats

scientific article published in December 2009

Vitamin A supplementation for different periods alters rat vascular redox parameters.

scientific article published on 19 August 2010

Vitamin A supplementation induces oxidative stress and decreases the immunocontent of catalase and superoxide dismutase in rat lungs

scientific article published in June 2009

Vitamin A treatment induces apoptosis through an oxidant-dependent activation of the mitochondrial pathway

scientific article published on 7 September 2007

cis-4-decenoic acid provokes mitochondrial bioenergetic dysfunction in rat brain

scientific article published on 9 June 2010

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