List of works - Gregory S. Barsh

-2019 PLOS Genetics Research Prize: Fruit fly school - language and dialects for communicating a threat

scientific article published on 12 September 2019

2018 PLOS Genetics Research Prize: Bundling, stabilizing, organizing-The orchestration of acentriolar spindle assembly by microtubule motor proteins

article

A -defensin mutation causes black coat color in domestic dogs

scientific article

A Decad(e) of Reasons to Contribute to a PLOS Community-Run Journal

scientific article

A Hox-Embedded Long Noncoding RNA: Is It All Hot Air?

scientific article

A mouse keratin 1 mutation causes dark skin and epidermolytic hyperkeratosis

scientific article published in May 2006

A state-based approach to genomics for rare disease and population screening

scientific article published on 27 November 2020

AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

scientific article

Aberrant Inclusion of a Poison Exon Causes Dravet Syndrome and Related SCN1A-Associated Genetic Epilepsies

scientific article published on 01 December 2018

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy

scientific article published on 07 January 2021

Accessory proteins for melanocortin signaling: attractin and mahogunin

scientific article

Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway

scientific article published on 26 May 2009

Ancestral components of admixed genomes in a Mexican cohort

scientific article

Association of an Agouti allele with fawn or sable coat color in domestic dogs

scientific article published in April 2005

Bringing PLOS Genetics Editors to Preprint Servers

scientific article published on December 2016

By what name shall I call thee?

scientific article published on 29 October 2020

Characterization of the dog Agouti gene and a nonagoutimutation in German Shepherd Dogs

scientific article

Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion

scientific article published on 27 December 2007

Coordinated regulation of hepatic energy stores by leptin and hypothalamic agouti-related protein

scientific article published on July 2013

David R. Cox 1946-2013.

scientific article published in July 2013

De novo mutations in the GTP/GDP-binding region of RALA, a RAS-like small GTPase, cause intellectual disability and developmental delay

scientific article published on 30 November 2018

Design, pharmacology, and NMR structure of a minimized cystine knot with agouti-related protein activity

scientific article

Developmental genetics of color pattern establishment in cats

scientific article published on 07 September 2021

Developmental mechanisms of stripe patterns in rodents

scientific article

Differences in dorsal and ventral pigmentation result from regional expression of the mouse agouti gene

scientific article published on June 1994

Digital gene expression for non-model organisms

scientific article

Diurnal rhythm of agouti-related protein and its relation to corticosterone and food intake

scientific article published in October 2002

Dog colour patterns explained by modular promoters of ancient canid origin

scientific article published on 12 August 2021

Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene

scientific article

Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons

scientific article published on November 2009

Dorsoventral patterning of the mouse coat by Tbx15

scientific article

Doubling down on forensic twin studies

Effects of G-protein mutations on skin color

scientific journal article

Effects of hypothalamic neurodegeneration on energy balance

scientific article

Electrostatic Similarity Analysis of Human β-Defensin Binding in the Melanocortin System

scientific article

Eliciting preferences on secondary findings: the Preferences Instrument for Genomic Secondary Results.

scientific article

Epigenetic models developed for plains zebras predict age in domestic horses and endangered equids

scientific article published on 17 December 2021

Evaluating the strength of genetic results: Risks and responsibilities

scientific article published on 11 October 2019

Evolutionary genomics: Detecting selection

scientific article published on 01 March 2013

Fibulin-5 mutation featuring Charcot-Marie-Tooth disease, joint hyperlaxity, and scoliosis

scientific article published on 25 June 2020

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi

scientific article

Genetic architecture of skin and eye color in an African-European admixed population

scientific article

Genetics of Sex-linked yellow in the Syrian hamster

scientific article

Genetics of dark skin in mice

scientific article

Genetics of shoulder girdle formation: roles of Tbx15 and aristaless-like genes

scientific journal article

Genome sequencing as a first-line diagnostic test for hospitalized infants

scientific article published on 29 November 2021

Genome-wide association studies of quantitatively measured skin, hair, and eye pigmentation in four European populations

scientific article

Genomic diagnosis for children with intellectual disability and/or developmental delay

scientific article

Genomic sequencing identifies secondary findings in a cohort of parent study participants

Guidelines for genome-wide association studies

scientific article published on 5 July 2012

Haploinsufficiency of Ribosomal Protein S6 In Mice Mimics Bone Marrow Failure Syndromes In Humans ⬇️

scholarly article

High frequency of an otherwise rare phenotype in a small and isolated tiger population

scientific article published in 2021

How the leopard hides its spots: ASIP mutations and melanism in wild cats

scientific article

Hypothalamic neurodegeneration and adult-onset obesity in mice lacking the Ubb polyubiquitin gene

scientific journal article

Identification of a Keratin 4 mutation in a chemically induced mouse mutant that models white sponge nevus

scientific article

Identifying rare, medically relevant variation via population-based genomic screening in Alabama: opportunities and pitfalls

scientific article published on 29 September 2020

In vivo epinephrine-mediated regulation of gene expression in human skeletal muscle

scientific article

In vivo regulation of human skeletal muscle gene expression by thyroid hormone

scientific article

Inactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (Pomc) neurons causes decreased pomc expression, mild obesity, and defects in compensatory refeeding

scientific article published on 5 October 2006

Independent regulation of hair and skin color by two G protein-coupled pathways

scientific article published on 21 July 2009

Inference on the Genetic Basis of Eye and Skin Color in an Admixed Population via Bayesian Linear Mixed Models

scientific article published on 4 April 2017

Interaction between alpha-melanocyte-stimulating hormone and corticotropin-releasing hormone in the regulation of feeding and hypothalamo-pituitary-adrenal responses.

scientific article published in August 2003

Inverse agonist activity of agouti and agouti-related protein.

scientific article

Is the energy homeostasis system inherently biased toward weight gain?

scientific article published in February 2003

Kingdom Come

scientific article published on 05 November 2020

Linkage and segregation analysis of black and brindle coat color in domestic dogs

scientific article

Loop-Swapped Chimeras of the Agouti-Related Protein and the Agouti Signaling Protein Identify Contacts Required for Melanocortin 1 Receptor Selectivity and Antagonism ⬇️

scientific article published on September 8, 2010

Loops and links: structural insights into the remarkable function of the agouti-related protein

scientific article

Making room for opinions

scientific article published on 28 February 2019

Mammalian comparative sequence analysis of the Agrp locus

scientific article

Melanocyte-lineage expression of Cre recombinase using Mitf regulatory elements

scientific article published in February 2008

Melanoma to Vitiligo: The Melanocyte in Biology & Medicine-Joint Montagna Symposium on the Biology of Skin/PanAmerican Society for Pigment Cell Research Annual Meeting

scientific article published on 23 July 2019

Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clamp

scientific article published on 5 March 2003

Mixed methods

scientific article published on 15 July 2020

Modeling 3D facial shape from DNA

scientific article

Molecular and evolutionary history of melanism in North American gray wolves

scientific article

Molecular and functional analysis of human β-defensin 3 action at melanocortin receptors

scientific article published on June 2013

Molecular and phenotypic analysis of Attractin mutant mice

scientific article

PEA15 loss of function and defective cerebral development in the domestic cat

scientific article published on 08 December 2020

PI3K integrates the action of insulin and leptin on hypothalamic neurons

scientific article

PLOS Genetics Data Sharing Policy: In Pursuit of Functional Utility

scientific article

Population structure, inbreeding and stripe pattern abnormalities in plains zebras

scientific article published on 10 November 2020

Recurrent evolution of melanism in South American felids.

scientific article

Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome ⬇️

scientific article published on July 25, 2011

Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss

scientific article

Regulatory mutations in TBX3 disrupt asymmetric hair pigmentation that underlies Dun camouflage color in horses

scientific article published on 21 December 2015

Response—How the Gray Wolf Got Its Color

scientific article published in Science

Return of raw data in genomic testing and research: ownership, partnership, and risk-benefit

scientific article published on 17 July 2019

Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects

scientific article published on 20 July 2008

Scientists<--editors<--scientists: the past, present, and future of PLoS Genetics

scientific article published on 31 July 2009

Secreted and membrane attractin result from alternative splicing of the human ATRN gene

scientific article

Signal transducer and activator of transcription (stat) binding sites but not stat3 are required for fasting-induced transcription of agouti-related protein messenger ribonucleic acid

scientific article published on 18 May 2006

Signals of recent positive selection in a worldwide sample of human populations

scientific article

Skin color variation in Africa

scientific article

Specifying and sustaining pigmentation patterns in domestic and wild cats

scientific article

Spongiform degeneration in mahoganoid mutant mice

scientific article

Structural and molecular evolutionary analysis of Agouti and Agouti-related proteins

scientific article

Structures of the agouti signaling protein

scientific article

Systematic reanalysis of genomic data improves quality of variant interpretation.

scientific article published on 13 April 2018

Tabby pattern genetics - a whole new breed of cat.

scientific article

The Language of Genetics In the Interviews of Jane Gitschier

scientific article published on 16 June 2016

The Plight of Muntaser Ibrahim

scientific article published on 25 March 2019

The mouse mahogany locus encodes a transmembrane form of human attractin

scientific article

The role of insulin receptor substrate 2 in hypothalamic and beta cell function.

scientific article

Transcriptional regulation of agouti-related protein (Agrp) in transgenic mice

scientific article published on 2 September 2004

Unexpected endocrine features and normal pigmentation in a young adult patient carrying a novel homozygous mutation in the POMC gene

scientific article published on 02 September 2008

Unraveling the thread of nature's tapestry: the genetics of diversity and convergence in animal pigmentation

scientific article published on July 2012

Weight loss regulates inflammation-related genes in white adipose tissue of obese subjects

scientific article published in November 2004

List of works by Gregory S. Barsh

-2019 PLOS Genetics Research Prize: Fruit fly school - language and dialects for communicating a threat

2018 PLOS Genetics Research Prize: Bundling, stabilizing, organizing-The orchestration of acentriolar spindle assembly by microtubule motor proteins

A -defensin mutation causes black coat color in domestic dogs

A Decad(e) of Reasons to Contribute to a PLOS Community-Run Journal

A Hox-Embedded Long Noncoding RNA: Is It All Hot Air?

A mouse keratin 1 mutation causes dark skin and epidermolytic hyperkeratosis

A state-based approach to genomics for rare disease and population screening

AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

Aberrant Inclusion of a Poison Exon Causes Dravet Syndrome and Related SCN1A-Associated Genetic Epilepsies

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy

Accessory proteins for melanocortin signaling: attractin and mahogunin

Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway

Ancestral components of admixed genomes in a Mexican cohort

Association of an Agouti allele with fawn or sable coat color in domestic dogs

Bringing PLOS Genetics Editors to Preprint Servers

By what name shall I call thee?

Characterization of the dog Agouti gene and a nonagoutimutation in German Shepherd Dogs

Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion

Coordinated regulation of hepatic energy stores by leptin and hypothalamic agouti-related protein

David R. Cox 1946-2013.

De novo mutations in the GTP/GDP-binding region of RALA, a RAS-like small GTPase, cause intellectual disability and developmental delay

Design, pharmacology, and NMR structure of a minimized cystine knot with agouti-related protein activity

Developmental genetics of color pattern establishment in cats

Developmental mechanisms of stripe patterns in rodents

Differences in dorsal and ventral pigmentation result from regional expression of the mouse agouti gene

Digital gene expression for non-model organisms

Diurnal rhythm of agouti-related protein and its relation to corticosterone and food intake

Dog colour patterns explained by modular promoters of ancient canid origin

Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene

Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons

Dorsoventral patterning of the mouse coat by Tbx15

Doubling down on forensic twin studies

Effects of G-protein mutations on skin color

Effects of hypothalamic neurodegeneration on energy balance

Electrostatic Similarity Analysis of Human β-Defensin Binding in the Melanocortin System

Eliciting preferences on secondary findings: the Preferences Instrument for Genomic Secondary Results.

Epigenetic models developed for plains zebras predict age in domestic horses and endangered equids

Evaluating the strength of genetic results: Risks and responsibilities

Evolutionary genomics: Detecting selection

Fibulin-5 mutation featuring Charcot-Marie-Tooth disease, joint hyperlaxity, and scoliosis

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi

Genetic architecture of skin and eye color in an African-European admixed population

Genetics of Sex-linked yellow in the Syrian hamster

Genetics of dark skin in mice

Genetics of shoulder girdle formation: roles of Tbx15 and aristaless-like genes

Genome sequencing as a first-line diagnostic test for hospitalized infants

Genome-wide association studies of quantitatively measured skin, hair, and eye pigmentation in four European populations

Genomic diagnosis for children with intellectual disability and/or developmental delay

Genomic sequencing identifies secondary findings in a cohort of parent study participants

Guidelines for genome-wide association studies

Haploinsufficiency of Ribosomal Protein S6 In Mice Mimics Bone Marrow Failure Syndromes In Humans ⬇️

High frequency of an otherwise rare phenotype in a small and isolated tiger population

How the leopard hides its spots: ASIP mutations and melanism in wild cats

Hypothalamic neurodegeneration and adult-onset obesity in mice lacking the Ubb polyubiquitin gene

Identification of a Keratin 4 mutation in a chemically induced mouse mutant that models white sponge nevus

Identifying rare, medically relevant variation via population-based genomic screening in Alabama: opportunities and pitfalls

In vivo epinephrine-mediated regulation of gene expression in human skeletal muscle

In vivo regulation of human skeletal muscle gene expression by thyroid hormone

Inactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (Pomc) neurons causes decreased pomc expression, mild obesity, and defects in compensatory refeeding

Independent regulation of hair and skin color by two G protein-coupled pathways

Inference on the Genetic Basis of Eye and Skin Color in an Admixed Population via Bayesian Linear Mixed Models

Interaction between alpha-melanocyte-stimulating hormone and corticotropin-releasing hormone in the regulation of feeding and hypothalamo-pituitary-adrenal responses.

Inverse agonist activity of agouti and agouti-related protein.

Is the energy homeostasis system inherently biased toward weight gain?

Kingdom Come

Linkage and segregation analysis of black and brindle coat color in domestic dogs

Loop-Swapped Chimeras of the Agouti-Related Protein and the Agouti Signaling Protein Identify Contacts Required for Melanocortin 1 Receptor Selectivity and Antagonism ⬇️

Loops and links: structural insights into the remarkable function of the agouti-related protein

Making room for opinions

Mammalian comparative sequence analysis of the Agrp locus

Melanocyte-lineage expression of Cre recombinase using Mitf regulatory elements

Melanoma to Vitiligo: The Melanocyte in Biology & Medicine-Joint Montagna Symposium on the Biology of Skin/PanAmerican Society for Pigment Cell Research Annual Meeting

Microarray profiling of human skeletal muscle reveals that insulin regulates approximately 800 genes during a hyperinsulinemic clamp

Mixed methods

Modeling 3D facial shape from DNA

Molecular and evolutionary history of melanism in North American gray wolves

Molecular and functional analysis of human β-defensin 3 action at melanocortin receptors

Molecular and phenotypic analysis of Attractin mutant mice

PEA15 loss of function and defective cerebral development in the domestic cat