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List of works by David M Kaye

A Single-Center Experience of the Optimal Initial Immunosuppressive Strategy for Preventing Early Acute Cellular Rejection in Orthotopic Heart Transplantation Associated With Renal Dysfunction

scientific article published on 02 September 2019

A Transcatheter InterAtrial Shunt Device for the Treatment of Heart Failure with Preserved Ejection Fraction (REDUCE LAP-HF I): A Phase 2, Randomized, Sham-Controlled Trial

scientific article published on 15 November 2017

A transcatheter intracardiac shunt device for heart failure with preserved ejection fraction (REDUCE LAP-HF): a multicentre, open-label, single-arm, phase 1 trial

scientific article published in March 2016

Accuracy of Doppler Echocardiography to Estimate Key Hemodynamic Variables in Subjects With Normal Left Ventricular Ejection Fraction ⬇️

scientific article published on February 22, 2011

Acute effects of continuous positive airway pressure on cardiac sympathetic tone in congestive heart failure

scientific article

Adrenergic nervous system in heart failure

scientific article published on December 1997

Adverse consequences of high sympathetic nervous activity in the failing human heart

scientific article published on November 1995

Adverse effects of cigarette smoke on NO bioavailability: role of arginine metabolism and oxidative stress

scientific article published on 26 June 2006

Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction

scientific article published on 22 May 2015

An age-related decline in endothelial function is not associated with alterations in L-arginine transport in humans

scientific article published in February 2004

Antiadrenergic effect of chronic amiodarone therapy in human heart failure

scientific article

Association of Socioeconomic Status With Outcomes and Care Quality in Patients Presenting With Undifferentiated Chest Pain in the Setting of Universal Health Care Coverage

scientific article published on 24 March 2022

Augmentation of endothelial function following exercise training is associated with increased L-arginine transport in human heart failure

scientific article published in December 2005

Augmentation of left ventricular mechanics by recirculation‐mediated AAV2/1–SERCA2a gene delivery in experimental heart failure ⬇️

scientific article published on February 2, 2011

Augmented endothelial l-arginine transport ameliorates pressure-overload-induced cardiac hypertrophy

scientific article published on July 2015

B-type natriuretic peptide: endogenous regulator of myocardial structure, biomarker and therapeutic target

scientific article published on September 2009

Beta-adrenoceptor genotype influences the response to carvedilol in patients with congestive heart failure

scientific article published in July 2003

Beyond pharmacological treatment: an insight into therapies that target specific aspects of heart failure pathophysiology

scientific article published on 01 March 2019

Biventricular pacing in heart failure: a review

scientific article

CXCR4 antagonism attenuates the cardiorenal consequences of mineralocorticoid excess

scientific article

Cardiac Gene Delivery Using Recirculating Devices

scientific article published in January 2017

Cardiac sympathetic nerve function in congestive heart failure

scientific article published on 01 May 1996

Cardiogenic genes expressed in cardiac fibroblasts contribute to heart development and repair

scientific article

Catecholamine Metabolites in Internal Jugular Plasma: A Window into the Human Brain

Cellular reprogramming: a new avenue to cardiac regeneration?

scientific article

Central and Peripheral Norepinephrine Kinetics in Heart Failure, Coronary Artery Disease, and Hypertension

scientific article published on 01 January 1998

Central nervous system monoamine neurotransmitter turnover in primary and obesity-related human hypertension

scientific article published on July 1997

Central nervous system noradrenergic control of sympathetic outflow in normotensive and hypertensive humans.

scientific article published on January 1995

Characterising risk of in-hospital mortality following cardiac arrest using machine learning: A retrospective international registry study

scientific article published on 30 November 2018

Chronic atrial fibrillation does not influence the magnitude of sympathetic overactivity in patients with heart failure

scientific article published in September 2003

Clinical treatment regimens for chronic heart failure: a review

scientific article

Continuous positive airway pressure decreases myocardial oxygen consumption in heart failure

scientific article published in June 2004

Cyclosporine therapy after cardiac transplantation causes hypertension and renal vasoconstriction without sympathetic activation

scientific article published on 01 September 1993

Deficiency of Prebiotic Fibre and Insufficient Signalling Through Gut Metabolite Sensing Receptors Leads to Cardiovascular Disease

scientific article published on 25 February 2020

Dietary supplementation with L-arginine fails to restore endothelial function in forearm resistance arteries of patients with severe heart failure.

scientific article published in April 1996

Differential Effect of Acute Baroreceptor Unloading on Cardiac and Systemic Sympathetic Tone in Congestive Heart Failure

scientific article published on 01 March 1998

Diffuse myocardial fibrosis in hypertrophic cardiomyopathy can be identified by cardiovascular magnetic resonance, and is associated with left ventricular diastolic dysfunction

scientific article

Diffuse ventricular fibrosis is a late outcome of tachycardia-mediated cardiomyopathy after successful ablation

scientific article

Divergent effects of ANP and BNP in acute heart failure: evidence for a putative BNP-selective receptor?

scientific article published in June 2002

Effect of iron chelation on myocardial infarct size and oxidative stress in ST-elevation-myocardial infarction.

scientific article published on 10 April 2012

Effect of sunlight and season on serotonin turnover in the brain.

scientific article

Effects of intravenous brain natriuretic peptide on regional sympathetic activity in patients with chronic heart failure as compared with healthy control subjects

scientific article published in April 2001

Electrocardiographic and echocardiographic features of left atrial size after orthotopic cardiac transplantation

scientific article published in October 1992

Endothelial cationic amino acid transporter-1 overexpression blunts the effects of oxidative stress on pressor responses to behavioural stress in mice

scientific article published on 01 December 2014

Endothelial dysfunction in patients with type 2 diabetes post acute coronary syndrome

scientific article published on 14 May 2013

Endothelial specific overexpression of cationic amino acid transporter-1 prevents loss of renal function in cardiorenal syndrome type 2

scientific article published on 09 October 2020

Erratum

scholarly article published in Current Medicinal Chemistry

Evaluating the utility of circulating biomarkers of collagen synthesis in hypertrophic cardiomyopathy

scientific article published on 30 January 2014

Evidence for functional presynaptic alpha-2 adrenoceptors and their down-regulation in human heart failure

scientific article published on April 2001

Exercise Hemodynamics as a Predictor of Myocardial Recovery in LVAD Patients

scientific article published on 2 December 2016

Extended-Release Oral Milrinone for the Treatment of Heart Failure With Preserved Ejection Fraction

scientific article published on 18 June 2020

Fallibility of plasma noradrenaline measurements in studying postprandial sympathetic nervous responses

article

Fatal Legionella longbeachae infection following heart transplantation.

scientific article

Feasibility and short-term efficacy of percutaneous mitral annular reduction for the therapy of heart failure-induced mitral regurgitation

scientific article published on 6 October 2003

Frequency-dependent activation of a constitutive nitric oxide synthase and regulation of contractile function in adult rat ventricular myocytes.

scientific article published in February 1996

Functional and neurochemical evidence for partial cardiac sympathetic reinnervation after cardiac transplantation in humans

scientific article published on 01 September 1993

Functional relevance of genetic variations of endothelial nitric oxide synthase and vascular endothelial growth factor in diabetic coronary microvessel dysfunction.

scientific article published on April 2013

Heart rate spectral analysis, cardiac norepinephrine spillover, and muscle sympathetic nerve activity during human sympathetic nervous activation and failure

scientific article published on 01 July 1994

Hemodynamic Profile of Patients With Heart Failure and Preserved Ejection Fraction Vary by Age.

scientific article published on 22 September 2017

Hemodynamic determinants of myocardial B-type natriuretic peptide release: relative contributions of systolic and diastolic wall stress

scientific article published on 16 August 2010

High-Fiber Diet and Acetate Supplementation Change the Gut Microbiota and Prevent the Development of Hypertension and Heart Failure in Hypertensive Mice.

scientific article

High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus

scientific article

Hospitalisation in Patients With Heart Failure With Preserved Ejection Fraction

scientific article published on 8 January 2018

Hypersensitivity myocarditis presenting as cardiogenic shock

scientific article published on 01 November 2001

Identification of a novel polymorphism in the 3'UTR of the L-arginine transporter gene SLC7A1: contribution to hypertension and endothelial dysfunction

scientific article published on 26 February 2007

Impact of Baseline Hemodynamics on the Effects of a Transcatheter Interatrial Shunt Device in Heart Failure With Preserved Ejection Fraction

scientific article published on 01 August 2018

Impact of Interatrial Shunts on Invasive Hemodynamics and Exercise Tolerance in Patients With Heart Failure

scientific article published in 2020

Impact of N-acetylcysteine on Endothelial Function, B-type Natriuretic Peptide and Renal Function in Patients with the Cardiorenal Syndrome: A Pilot Cross Over Randomised Controlled Trial ⬇️

scientific article published on December 7, 2012

Impact of Sex on Ventricular-Vascular Stiffness and Long-Term Outcomes in Heart Failure With Preserved Ejection Fraction: TOPCAT Trial Substudy

scientific article published on 22 June 2019

Impaired L-arginine transport and endothelial function in hypertensive and genetically predisposed normotensive subjects

scientific article published on 29 November 2004

Impaired l-arginine-nitric oxide pathway contributes to the pathogenesis of resistant hypertension

scientific article published on 01 October 2019

Impaired myocardial oxygen availability contributes to abnormal exercise hemodynamics in heart failure with preserved ejection fraction

scientific article

Improved outcomes from a comprehensive management system for heart failure

scientific article published on 01 October 2001

In vivo and in vitro evidence for impaired arginine transport in human heart failure

scientific article published on 01 November 2000

Increased brain serotonin turnover in panic disorder patients in the absence of a panic attack: reduction by a selective serotonin reuptake inhibitor

scientific article

Increased central nervous system monoamine neurotransmitter turnover and its association with sympathetic nervous activity in treated heart failure patients

scientific article published on 01 October 1995

Increased long-term mortality in heart failure due to sleep apnoea is not yet proven

scientific article published in May 2004

Increased sympathetic nervous system activity and its therapeutic reduction in arterial hypertension, portal hypertension and heart failure

scientific article published on 01 October 1998

Influence of ageing on the sympathetic nervous system and adrenal medulla at rest and during stress

scientific article

Influence of pulmonary capillary wedge pressure on central apnea in heart failure

scientific article

Insulin replacement limits progression of diabetic cardiomyopathy in the low-dose streptozotocin-induced diabetic rat.

scientific article published on May 2017

Interactions between leptin and the human sympathetic nervous system

scientific article published on 31 March 2003

Irregular Rhythm Adversely Influences Calcium Handling in Ventricular Myocardium

article

Is very high sympathetic tone in heart failure a result of keeping bad company?

scientific article published on 20 October 2003

L-arginine transport in humans with cortisol-induced hypertension

scientific article published on 21 April 2003

Leptin in human plasma is derived in part from the brain, and cleared by the kidneys

scientific article published in March 1998

Letter by Kaye and Esler regarding article "extracardiac progenitor cells repopulate most major cell types in the transplanted human heart"

scientific article published on 01 June 2006

Measurement of sympathetic nervous system activity in heart failure: the role of norepinephrine kinetics

scientific article

Mechanisms of carvedilol action in human congestive heart failure

scientific article published in May 2001

Monoaminergic neuronal activity in subcortical brain regions in essential hypertension

scientific article

Myocardial Fibrosis in Hypertrophic Cardiomyopathy ⬇️

scientific article published on November 11, 2010

Myocardial ischemia-reperfusion injury, antioxidant enzyme systems, and selenium: a review

scientific article published on January 2007

Neural mechanisms in human obesity-related hypertension

scientific article published on 01 August 1999

Neurochemical evidence of cardiac sympathetic activation and increased central nervous system norepinephrine turnover in severe congestive heart failure.

scientific article

Neurohormonal assessment of cardiac function

scientific article

Non-invasive blood pressure monitoring underestimates hypertensive response to exercise in suspected heart failure with preserved ejection fraction

scientific article published on 03 September 2019

One-Year Outcomes After Transcatheter Insertion of an Interatrial Shunt Device for the Management of Heart Failure With Preserved Ejection Fraction

scientific article published in December 2016

Percutaneous mitral annular reduction provides continued benefit in an ovine model of dilated cardiomyopathy

scientific article published on 25 October 2004

Percutaneous mitral annuloplasty for functional mitral regurgitation: results of the CARILLON Mitral Annuloplasty Device European Union Study.

scientific article published on 13 July 2009

Phenotypic evidence of faulty neuronal norepinephrine reuptake in essential hypertension

scientific article published on 01 November 2000

Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling.

scientific article

Population-Based Gut Microbiome Associations With Hypertension

scientific article published on 01 November 2018

Post cardiac arrest syndrome: a review of therapeutic strategies

scientific article published on April 2011

Principles, current status and clinical implications of ischaemic heart disease assessment by cardiac magnetic resonance imaging ⬇️

scientific article published on January 1, 2012

Quantitative analysis of PDGFA, PDGFB, PDGF receptor β and TGF-β1 mRNA in cardiac transplant biopsies

scientific article published on 01 February 1999

Raised sympathetic nerve activity in heart failure and central sleep apnea is due to heart failure severity

scientific article published in March 2003

Reduced myocardial and systemic L-arginine uptake in heart failure

scientific article published in December 2002

Region-specific neuropeptide Y overflows at rest and during sympathetic activation in humans.

scientific article published in January 1997

Regional 5-hydroxyindoleacetic acid production in humans.

scientific article published on January 1995

Regional epinephrine kinetics in human heart failure: evidence for extra-adrenal, nonneural release ⬇️

scientific article published on 01 July 1995

Regional origins of 3-methoxy-4-hydroxyphenylglycol in plasma: effects of chronic sympathetic nervous activation and denervation, and acute reflex sympathetic stimulation

scientific article published on 01 November 1995

Regional sympathetic effects of low-dose clonidine in heart failure

scientific article published on 24 February 2003

Relation between cardiac sympathetic activity and hypertensive left ventricular hypertrophy

scientific article published on 7 July 2003

Relationship of circulating matrix biomarkers to myocardial matrix metabolism in advanced heart failure ⬇️

scientific article published on 09 November 2012

Removal of Contrast Media From the Coronary Sinus Attenuates Renal Injury After Coronary Angiography and Intervention ⬇️

scientific article published on 01 August 2010

Response to Letter Regarding Article, "Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction"

scientific article published on 01 January 2016

Restoration of nitric oxide function in human hyperlipidaemia, congestive heart failure and liver cirrhosis ⬇️

scientific article published on 01 September 1998

Review of the current management of atrial fibrillation

scientific article published on November 2003

Role of AT1and AT2receptors in regulation of MAPKs and MKP-1 by ANG II in adult cardiac myocytes ⬇️

scientific article published on 01 September 1998

Role of mitochondrial dysfunction in hyperglycaemia-induced coronary microvascular dysfunction: Protective role of resveratrol.

scientific article published on 12 March 2015

Role of transiently altered sarcolemmal membrane permeability and basic fibroblast growth factor release in the hypertrophic response of adult rat ventricular myocytes to increased mechanical activity in vitro

scientific article published on January 1996

Say NO to Obesity-Related Hypertension: Role of the L-Arginine-Nitric Oxide Pathway.

scientific article published on 28 March 2016

Selective Recertification of Pilots Who Have Undergone a Cardiac Transplant

scientific article published on 01 September 2020

Serelaxin attenuates renal inflammation and fibrosis in a mouse model of dilated cardiomyopathy

scientific article published on 05 November 2018

Sex Differences in Cardiovascular Pathophysiology: Why Women Are Overrepresented in Heart Failure With Preserved Ejection Fraction

scientific article published on 01 July 2018

Single‐unit muscle sympathetic nervous activity and its relation to cardiac noradrenaline spillover ⬇️

article by Elisabeth Lambert et al published 15 May 2011 in Journal of Physiology

Subclinical Left Ventricular Dysfunction is Influenced by Genotype Severity in Patients with Cystic Fibrosis

scientific article published on 19 August 2018

Sympathetic augmentation in hypertension: role of nerve firing, norepinephrine reuptake, and Angiotensin neuromodulation

scientific article published on 10 November 2003

Sympathetic nervous activity and the thermic effect of food in humans

scientific article published in January 1998

Sympathetic nervous system activation in essential hypertension, cardiac failure and psychosomatic heart disease

scientific article

Temporal changes in diastolic function in heart failure patients with restrictive filling ⬇️

scientific article published on November 21, 2010

The 'adrenaline hypothesis' of hypertension revisited: evidence for adrenaline release from the heart of patients with essential hypertension

scientific article published on 01 June 2000

The Effect of Successful Heart Transplant Treatment of Heart Failure on Central Sleep Apnea * ⬇️

scientific article published on November 1, 2003

The effect of selective intestinal decontamination on the hyperdynamic circulatory state in cirrhosis. A randomized trial

scientific article published in August 2003

The failing human heart does not release nitrogen oxides

scientific article published on 01 January 1998

The gut microbiota and blood pressure in experimental models

scientific article published on 01 March 2019

The neuronal noradrenaline transporter, anxiety and cardiovascular disease

scientific article (publication date: July 2006)

The prognostic significance of chronotropic incompetence in patients with severe left ventricular systolic function referred for cardiac transplant assessment

scientific article published on 19 June 2018

The role of the NO pathway in the control of cardiac function.

scientific article

Transcatheter Interatrial Shunt Device for the Treatment of Heart Failure: Rationale and Design of the Randomized Trial to REDUCE Elevated Left Atrial Pressure in Heart Failure (REDUCE LAP-HF I).

scientific article published on July 2016

beta-Adrenoceptor-mediated, nitric-oxide-dependent vasodilatation is abnormal in early hypertension: restoration by L-arginine

scientific article published in October 2004

beta-blockers, angiotensin II, and ACE inhibitors in patients with heart failure

scientific article published on 01 November 2001

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