List of works by Lawrence J Bonassar

3013 Combined Annulus Fibrosus and Nucleus Pulposus Repair Prevents Degeneration in the Ovine Lumbar Spine

A Biomechanical Analysis of an Engineered Cell-Scaffold Implant for Cartilage Repair

scientific article published on 01 May 2001

A composite tissue‐engineered trachea using sheep nasal chondrocyte and epithelial cells ⬇️

scientific article published on May 1, 2003

A mechanical composite spheres analysis of engineered cartilage dynamics.

scientific article

A microfluidic biomaterial.

scientific article published in October 2005

A model system for developing a tissue engineered meniscal enthesis

scientific article published on 28 October 2016

A novel approach to regenerating periodontal tissue by grafting autologous cultured periosteum

scientific article

A novel injectable approach for cartilage formation in vivo using PLG microspheres.

scientific article published in March 2004

A pre-clinical test platform for the functional evaluation of scaffolds for musculoskeletal defects: the meniscus

scientific article

Abstract 102: Scaffolding the Scaffold: Mitigating Loss of Volume and Topography of Engineered Auricular Cartilage Using 3D Printed Contour Matching Cages.

scientific article

Abstract 129: Fabrication of the First Full-Scale Human Auricular Chondrocyte Derived Ear Scaffold for Clinical Application.

scientific article

Abstract: Scaffolding the Scaffold: 3D-Printed External Biodegradable Cage Mitigates Contraction during Maturation of Elastic Cartilage Constructs.

scientific article published in September 2017

Additive manufacturing for in situ repair of osteochondral defects

scientific article published on 08 September 2010

Adhesion and integration of tissue engineered cartilage to porous polyethylene for composite ear reconstruction.

scientific article published on 6 September 2014

Adhesive properties of laminated alginate gels for tissue engineering of layered structures

scientific article published in June 2008

Age dependence of biochemical and biomechanical properties of tissue-engineered human septal cartilage

scientific article published in August 2002

Age-related changes in the composition and mechanical properties of human nasal cartilage

scientific article

Alteration of articular cartilage frictional properties by transforming growth factor beta, interleukin-1beta, and oncostatin M.

scientific article published in February 2009

An allogenic cell-based implant for meniscal lesions

scientific article published on 26 July 2006

An optical method for evaluation of geometric fidelity for anatomically shaped tissue-engineered constructs

scientific article

Analysis of bending behavior of native and engineered auricular and costal cartilage.

scientific article published in March 2004

Analysis of frictional behavior and changes in morphology resulting from cartilage articulation with porous polyurethane foams

scientific article published on 01 October 2010

Anatomic variation of depth-dependent mechanical properties in neonatal bovine articular cartilage

scientific article published on 31 December 2012

Annular repair using high-density collagen gel: a rat-tail in vivo model

scientific article published on February 2014

Annulus Fibrosus Repair Using High-Density Collagen Gel: An In vivo Ovine Model.

scientific article

Assessment of intervertebral disc degeneration based on quantitative magnetic resonance imaging analysis: an in vivo study

scientific article

Autologous tissue-engineered trachea with sheep nasal chondrocytes

scientific article published on 01 June 2002

Binding and localization of recombinant lubricin to articular cartilage surfaces.

scientific article published in March 2007

Binding and lubrication of biomimetic boundary lubricants on articular cartilage

scientific article

Biologic Annulus Fibrosus Repair: A Review of Preclinical In Vivo Investigations

scientific article published on 4 November 2017

Biological Treatment Approaches for Degenerative Disk Disease: A Literature Review of In Vivo Animal and Clinical Data

scientific article

Biological intervertebral disc replacement: an in vivo model and comparison of two surgical techniques to approach the rat caudal disc

scientific article published on February 2011

Biomechanical Analysis of a Chondrocyte-Based Repair Model of Articular Cartilage

scientific article published on 01 August 1999

Biomechanical and biochemical characterization of composite tissue-engineered intervertebral discs

scientific article published on 13 September 2005

Biomechanical and biochemical characterization of porcine tracheal cartilage

scientific article published on 30 January 2016

Boundary mode lubrication of articular cartilage by recombinant human lubricin

scientific article published in June 2009

Boundary mode lubrication of articular cartilage with a biomimetic diblock copolymer

scientific article published on 04 June 2019

Calcium signaling in response to fluid flow by chondrocytes in 3D alginate culture

scientific article

Cartilage Articulation Exacerbates Chondrocyte Damage and Death After Impact Injury

scientific article published on 04 December 2020

Cell(MC3T3-E1)-printed poly(ϵ-caprolactone)/alginate hybrid scaffolds for tissue regeneration

scientific article

Cell-based bonding of articular cartilage: An extended study

scientific article published on 01 March 2003

Cell-laden poly(ɛ-caprolactone)/alginate hybrid scaffolds fabricated by an aerosol cross-linking process for obtaining homogeneous cell distribution: fabrication, seeding efficiency, and cell proliferation and distribution

scientific article published on 10 April 2013

Cells (MC3T3-E1)-laden alginate scaffolds fabricated by a modified solid-freeform fabrication process supplemented with an aerosol spraying

scientific article published on 30 August 2012

Cellular and Chemical Gradients to Engineer the Meniscus-to-Bone Insertion

scientific article published on 10 December 2018

Characterization of Tissue Response to Impact Loads Delivered Using a Hand-Held Instrument for Studying Articular Cartilage Injury

scientific article

Characterization of mesenchymal stem cells and fibrochondrocytes in three-dimensional co-culture: analysis of cell shape, matrix production, and mechanical performance

scientific article published on 12 March 2016

Chondrocyte calcium signaling in response to fluid flow is regulated by matrix adhesion in 3-D alginate scaffolds

scientific article published on 10 August 2010

Clinical doses of radiation reduce collagen matrix stiffness

scientific article published on 03 April 2018

Combined nucleus pulposus augmentation and annulus fibrosus repair prevents acute intervertebral disc degeneration after discectomy

scientific article published on 01 March 2020

Comparison of chondrogensis in static and perfused bioreactor culture

scientific article published on 01 September 2000

Comparison of tracheal and nasal chondrocytes for tissue engineering of the trachea

scientific article

Computed tomography-guided tissue engineering of upper airway cartilage

scientific article

Conditions affecting cell seeding onto three-dimensional scaffolds for cellular-based biodegradable implants

scientific article published on 01 October 2009

Control of the Electromechanical Properties of Alginate Hydrogels via Ionic and Covalent Cross-Linking and Microparticle Doping

article

Correlating rheological properties and printability of collagen bioinks: the effects of riboflavin photocrosslinking and pH.

scientific article published on 5 July 2017

Correlation between hearing loss and scala media area in guinea pigs with long-standing endolymphatic hydrops

scientific article published in January 2003

Degenerative changes of the canine cervical spine after discectomy procedures, an in vivo study

scientific article

Degradation alters the lubrication of articular cartilage by high viscosity, hyaluronic acid-based lubricants

scientific article published on 25 October 2017

Dense type I collagen matrices that support cellular remodeling and microfabrication for studies of tumor angiogenesis and vasculogenesis in vitro

scientific article

Direct freeform fabrication of seeded hydrogels in arbitrary geometries

scientific article

Distinct tribological endotypes of pathological human synovial fluid reveal characteristic biomarkers and variation in efficacy of viscosupplementation at reducing local strains in articular cartilage

scientific article published on 24 February 2020

Dose-dependent response of tissue-engineered intervertebral discs to dynamic unconfined compressive loading

scientific article

Dynamic compressive loading of image-guided tissue engineered meniscal constructs ⬇️

scientific article published on February 3, 2011

Dynamics of Synovial Fluid Aggregation under Shear

scientific article published on 23 October 2019

Effect of Lubricin Mimetics on the Inhibition of Osteoarthritis in a Rat Anterior Cruciate Ligament Transection Model

scientific article published on 31 January 2020

Effect of media mixing on ECM assembly and mechanical properties of anatomically-shaped tissue engineered meniscus

scientific article published on 12 June 2010

Effect of sustained-release PDGF and TGF-beta on cyclophosphamide-induced impaired wound healing

scientific article published on 01 October 2009

Effects of chitosan coatings on polypropylene mesh for implantation in a rat abdominal wall model

scientific article published on 21 August 2013

Effects of enzymatic treatments on the depth-dependent viscoelastic shear properties of articular cartilage

scientific article published on 05 September 2014

Elastoviscous Transitions of Articular Cartilage Reveal a Mechanism of Synergy between Lubricin and Hyaluronic Acid

scientific article published on 24 November 2015

Enhanced boundary lubrication properties of engineered menisci by lubricin localization with insulin-like growth factor I treatment.

scientific article published on 22 October 2013

Fabrication of tissue engineered tympanic membrane patches using computer-aided design and injection molding

scientific article published in July 2004

Fiber development and matrix production in tissue-engineered menisci using bovine mesenchymal stem cells and fibrochondrocytes

scientific article published on 7 December 2016

Fibroblasts regulate contractile force independent of MMP activity in 3D-collagen.

scientific article published in December 2003

Fibronectin mediates enhanced wear protection of lubricin during shear.

scientific article published on 29 July 2015

Frictional characterization of injectable hyaluronic acids is more predictive of clinical outcomes than traditional rheological or viscoelastic characterization

Frictional properties of the meniscus improve after scaffold-augmented repair of partial meniscectomy: a pilot study

scientific article

Galectin-3 Binds to Lubricin and Reinforces the Lubricating Boundary Layer of Articular Cartilage

scientific article published on 9 May 2016

Heterogeneous matrix deposition in human tissue engineered cartilage changes the local shear modulus and resistance to local construct buckling

scientific article published on 24 March 2020

High density cell seeding affects the rheology and printability of collagen bioinks

scientific article published on 22 August 2019

High density type I collagen gels for tissue engineering of whole menisci.

scientific article published on 10 May 2013

High-fidelity tissue engineering of patient-specific auricles for reconstruction of pediatric microtia and other auricular deformities

scientific article

High-resolution spatial mapping of shear properties in cartilage.

scientific article

Histomorphometric Analysis of a Cell-Based Model of Cartilage Repair

scientific article published on 01 October 2002

How can 50 years of solute transport data in articular cartilage inform the design of arthritis therapeutics?

scientific article published on 24 July 2018

Human talar and femoral cartilage have distinct mechanical properties near the articular surface

scientific article

Hyaline Articular Matrix Formed by Dynamic Self-Regenerating Cartilage and Hydrogels

scientific article published on 20 June 2016

Hypoxic Expansion of Human Mesenchymal Stem Cells Enhances Three-Dimensional Maturation of Tissue-Engineered Intervertebral Discs

scientific article published on 30 November 2016

Identification of cartilage injury using quantitative multiphoton microscopy

scientific article

Image-based tissue engineering of a total intervertebral disc implant for restoration of function to the rat lumbar spine

scientific article published on 8 March 2011

Image-guided tissue engineering

scientific article published on 06 July 2009

Image-guided tissue engineering of anatomically shaped implants via MRI and micro-CT using injection molding

scientific article

Imaging the local biochemical content of native and injured intervertebral disc using Fourier transform infrared microscopy

scientific article published on 14 September 2020

In vitro culture increases mechanical stability of human tissue engineered cartilage constructs by prevention of microscale scaffold buckling.

scientific article

In vitro tissue engineering to generate a human-sized auricle and nasal tip

scientific article published on 01 January 2003

In vivo annular repair using high-density collagen gel seeded with annulus fibrosus cells

scientific article published on 05 July 2018

In vivo tibial compression decreases osteolysis and tumor formation in a human metastatic breast cancer model

scientific article published in November 2013

Increased mixing improves hydrogel homogeneity and quality of three-dimensional printed constructs

scientific article published on 07 December 2010

Induction of fiber alignment and mechanical anisotropy in tissue engineered menisci with mechanical anchoring.

scientific article published on 26 February 2015

Inflammatory and Non-Inflammatory Synovial Fluids Exhibit New & Distinct Tribological Endotypes

scientific article published on 25 June 2020

Influence of Block Length on Articular Cartilage Lubrication with a Diblock Bottle-Brush Copolymer

scientific article published on 19 December 2019

Initial investigation of individual and combined annulus fibrosus and nucleus pulposus repair ex vivo.

scientific article published on 29 June 2017

Injectable tissue-engineered cartilage with different chondrocyte sources

scientific article published in April 2004

Injectable, high-density collagen gels for annulus fibrosus repair: An in vitro rat tail model

scientific article published on 29 December 2014

Insights into interstitial flow, shear stress, and mass transport effects on ECM heterogeneity in bioreactor-cultivated engineered cartilage hydrogels

scientific article published on 19 August 2011

Integration of layered chondrocyte-seeded alginate hydrogel scaffolds

scientific article published on 5 March 2007

Integrative repair of cartilage with articular and nonarticular chondrocytes.

scientific article published in September 2004

Integrin α10β1-Selected Mesenchymal Stem Cells Mitigate the Progression of Osteoarthritis in an Equine Talar Impact Model

scientific article published on 31 January 2020

Joint-dependent response to impact and implications for post-traumatic osteoarthritis

scientific article published on 26 February 2015

Local and global measurements show that damage initiation in articular cartilage is inhibited by the surface layer and has significant rate dependence

scientific article published on 02 March 2018

Localization of viscous behavior and shear energy dissipation in articular cartilage under dynamic shear loading

scientific article published in March 2013

Long-Term Morphological and Microarchitectural Stability of Tissue-Engineered, Patient-Specific Auricles In Vivo

scientific article published on 5 February 2016

Lubrication mode analysis of articular cartilage using Stribeck surfaces

scientific article

Mapping the depth dependence of shear properties in articular cartilage

scientific article published on 10 July 2008

Mathematical modeling and frequency gradient analysis of cellular and vascular invasion into integra and strattice: toward optimal design of tissue regeneration scaffolds

scientific article published on January 2012

Matrix metalloproteinase activity synergizes with alpha2beta1 integrins to enhance collagen remodeling.

scientific article published on October 2005

Matrix stiffening promotes a tumor vasculature phenotype.

scientific article published on 29 December 2016

Measurement of local diffusion and composition in degraded articular cartilage reveals the unique role of surface structure in controlling macromolecular transport

article

Measurement of local strains in intervertebral disc anulus fibrosus tissue under dynamic shear: contributions of matrix fiber orientation and elastin content.

scientific article published on 06 August 2009

Measuring microscale strain fields in articular cartilage during rapid impact reveals thresholds for chondrocyte death and a protective role for the superficial layer.

scientific article

Mechanical characterization of matrix-induced autologous chondrocyte implantation (MACI®) grafts in an equine model at 53 weeks

scientific article published on 15 April 2015

Mechanical properties and structure-function relationships in articular cartilage repaired using IGF-I gene-enhanced chondrocytes

scientific article published on 26 August 2015

Mechanical properties and structure-function relationships of human chondrocyte-seeded cartilage constructs after in vitro culture

scientific article published on 7 February 2017

Mesenchymal Stem Cell-Seeded High-Density Collagen Gel for Annular Repair: 6-Week Results From In Vivo Sheep Models

scientific article published on 01 August 2019

Methods for Photocrosslinking Alginate Hydrogel Scaffolds with High Cell Viability

article

Microfluidic scaffolds for tissue engineering

scientific article published on 30 September 2007

Microscale frictional strains determine chondrocyte fate in loaded cartilage.

scientific article published on 25 April 2018

Microscale strain mapping demonstrates the importance of interface slope in the mechanics of cartilage repair

scientific article published on 03 December 2020

Microstructured templates for directed growth and vascularization of soft tissue in vivo

scientific article published on 06 May 2011

Mineral Distribution Spatially Patterns Bone Marrow Stromal Cell Behavior on Monolithic Bone Scaffolds

scientific article published on 29 May 2020

Mitochondrial dysfunction is an acute response of articular chondrocytes to mechanical injury

scientific article published on 11 July 2017

Mitoprotective therapy preserves chondrocyte viability and prevents cartilage degeneration in an ex vivo model of posttraumatic osteoarthritis.

scientific article published on 22 February 2018

Mitoprotective therapy prevents rapid, strain-dependent mitochondrial dysfunction after articular cartilage injury

scientific article published on 16 December 2019

Modeling the dynamic composition of engineered cartilage.

scientific article published in December 2002

Modulation of lubricin biosynthesis and tissue surface properties following cartilage mechanical injury

scientific article published on 01 January 2009

Molecular transport in articular cartilage - what have we learned from the past 50 years?

scientific article published on 01 July 2018

Multiscale Strain as a Predictor of Impact-Induced Fissuring in Articular Cartilage.

scientific article

Multiscale mechanics of tissue-engineered cartilage grown from human chondrocytes and human-induced pluripotent stem cells

scientific article published on 03 March 2020

Next Generation Tissue Engineering of Orthopedic Soft Tissue-to-Bone Interfaces

scientific article published in September 2017

Non-enzymatic glycation of chondrocyte-seeded collagen gels for cartilage tissue engineering

scientific article published in November 2008

Normal Features of Tissue‐Engineered Auricular Cartilage by Flow Cytometry and Histology: Patient Safety ⬇️

scientific article published on October 1, 2003

Optimizing cell sourcing for clinical translation of tissue engineered ears

scientific article published on 5 December 2016

Physiologically Distributed Loading Patterns Drive the Formation of Zonally Organized Collagen Structures in Tissue-Engineered Meniscus

scientific article published in June 2016

Poly(lactide-co-glycolide) microspheres as a moldable scaffold for cartilage tissue engineering.

scientific article published in May 2005

Porous Poly(Vinyl Alcohol)-Hydrogel Matrix-Engineered Biosynthetic Cartilage ⬇️

scientific article published on October 12, 2010

Post-traumatic osteoarthritis of the ankle: A distinct clinical entity requiring new research approaches

scientific article

Prevention of cartilage degeneration in a rat model of osteoarthritis by intraarticular treatment with recombinant lubricin

scientific article published on 01 March 2009

Processing of type I collagen gels using nonenzymatic glycation

scientific article published on June 2010

Properties of cartilage engineered from elderly human chondrocytes for articular surface repair

scientific article published on 05 June 2012

Proteoglycan removal by chondroitinase ABC improves injectable collagen gel adhesion to annulus fibrosus

scientific article published on 16 August 2019

Rapid 3D printing of anatomically accurate and mechanically heterogeneous aortic valve hydrogel scaffolds

scientific article

Recent advances in biological therapies for disc degeneration: tissue engineering of the annulus fibrosus, nucleus pulposus and whole intervertebral discs

scientific article published on 14 June 2013

Regulation of proteoglycan production by varying glucose concentrations controls fiber formation in tissue engineered menisci

scientific article published on 20 September 2019

Resorbable plating system stabilizes tissue-engineered intervertebral discs implanted ex vivo in canine cervical spines

scientific article published on 30 August 2018

Review of injectable cartilage engineering using fibrin gel in mice and swine models

scientific article published on May 2006

Riboflavin crosslinked high-density collagen gel for the repair of annular defects in intervertebral discs: An in vivo study

scientific article

Role for interleukin 1alpha in the inhibition of chondrogenesis in autologous implants using polyglycolic acid-polylactic acid scaffolds.

scientific article published in January 2005

Role of TGF-beta and FGF in the treatment of radiation-impaired wounds using a novel drug delivery system

scientific article published in October 2008

Self-assembly of aligned tissue-engineered annulus fibrosus and intervertebral disc composite via collagen gel contraction

scientific article published on April 2010

Spatial periodicity in growth plate shear mechanical properties is disrupted by vitamin D deficiency

scientific article

Stable recombinant production of codon-scrambled lubricin and mucin in human cells

scientific article published on 08 March 2019

Stribeck Curve Analysis of Temporomandibular Joint Condylar Cartilage and Disc

scientific article published on 01 March 2019

Structure-function relations and rigidity percolation in the shear properties of articular cartilage

scientific article

Sub-critical impact inhibits the lubricating mechanisms of articular cartilage

scientific article published on 29 December 2016

Synergistic Interactions of a Synthetic Lubricin-Mimetic with Fibronectin for Enhanced Wear Protection

scientific article

Temporal changes in synovial fluid composition and elastoviscous lubrication in the equine carpal fracture model

scientific article published on 28 March 2019

The Effect of Antibody Size and Mechanical Loading on Solute Diffusion Through the Articular Surface of Cartilage.

scientific article published on 3 July 2017

The clot thickens: Autologous and allogeneic fibrin sealants are mechanically equivalent in an ex vivo model of cartilage repair

scientific article published on 08 November 2019

The effect of IGF-I on anatomically shaped tissue-engineered menisci.

scientific article published on 4 April 2013

The effect of hypoxia on thermosensitive poly(N-vinylcaprolactam) hydrogels with tunable mechanical integrity for cartilage tissue engineering

scientific article published on 30 May 2016

The effect of the duration of mechanical stimulation and post-stimulation culture on the structure and properties of dynamically compressed tissue-engineered menisci

scientific article published on 26 April 2012

The effects of needle puncture injury on microscale shear strain in the intervertebral disc annulus fibrosus

scientific article

Tissue Engineering Auricular Cartilage Using Late Passage Human Auricular Chondrocytes

scientific article published on 01 April 2018

Tissue engineering cartilage with aged articular chondrocytes in vivo

scientific article published in July 2006

Tissue engineering of autologous cartilage for craniofacial reconstruction by injection molding.

scientific article published in September 2003

Tissue engineering the human auricle by auricular chondrocyte-mesenchymal stem cell co-implantation

scientific article published in PLoS ONE

Tissue engineering: The first decade and beyond

scientific article published in January 1998

Tissue-engineered calcium alginate patches in the repair of chronic chinchilla tympanic membrane perforations

scientific article published in May 2006

Tissue-engineered composites of anulus fibrosus and nucleus pulposus for intervertebral disc replacement

scientific article

Tissue-engineered intervertebral discs produce new matrix, maintain disc height, and restore biomechanical function to the rodent spine

scientific article

Tissue-engineered intervertebral discs: MRI results and histology in the rodent spine.

scientific article

Tissue-engineered lung: an in vivo and in vitro comparison of polyglycolic acid and pluronic F-127 hydrogel/somatic lung progenitor cell constructs to support tissue growth

scientific article

Tissue-engineered total disc replacement: final outcomes of a murine caudal disc in vivo study

scientific article

Top-down Fabrication of Spatially Controlled Mineral-Gradient Scaffolds for Interfacial Tissue Engineering

scientific article published on 07 May 2019

Total disc replacement using a tissue-engineered intervertebral disc in vivo: new animal model and initial results.

scientific article

Total disc replacement using tissue-engineered intervertebral discs in the canine cervical spine

scientific article published on 20 October 2017

Tunable Lubricin-mimetics for Boundary Lubrication of Cartilage

Tuning three-dimensional collagen matrix stiffness independently of collagen concentration modulates endothelial cell behavior

scientific article

Understanding the Stiff-to-Compliant Transition of the Meniscal Attachments by Spatial Correlation of Composition, Structure, and Mechanics

scientific article published on 18 July 2019

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