List of works - Alexander Drilon

A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors

scientific article published on 3 June 2017

A Performance Comparison of Commonly Used Assays to Detect RET Fusions

scientific article published on 03 December 2020

A Phase I/Ib Trial of the VEGFR-Sparing Multikinase RET Inhibitor RXDX-105

scientific article published on 28 November 2018

A Phase Ib/II Study of Ramucirumab in Combination with Emibetuzumab in Patients with Advanced Cancer

scientific article published on 29 May 2019

Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms

scientific article published on 25 November 2019

Antitumor activity of crizotinib in lung cancers harboring a MET exon 14 alteration

scientific article published on 13 January 2020

Colorectal Carcinomas Containing Hypermethylated MLH1 Promoter and Wild-Type BRAF/KRAS Are Enriched for Targetable Kinase Fusions

scientific article published on 14 January 2019

Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes

scientific article published in 2021

Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children.

scientific article published in February 2018

High Yield of RNA Sequencing for Targetable Kinase Fusions in Lung Adenocarcinomas with No Mitogenic Driver Alteration Detected by DNA Sequencing and Low Tumor Mutation Burden

scientific article published on 26 April 2019

Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA

scientific article published on 28 April 2022

MAPK pathway alterations correlate with poor survival and drive resistance to therapy in patients with lung cancers driven by ROS1 fusions

scientific article published on 02 March 2020

MET exon 14-altered lung cancers and MET inhibitor resistance

scientific article published on 10 November 2020

MET-dependent solid tumours - molecular diagnosis and targeted therapy

scientific article published on 08 June 2020

NTRK fusion detection across multiple assays and 33,997 cases: diagnostic implications and pitfalls

scientific article published on 02 August 2019

NTRK fusion-positive cancers and TRK inhibitor therapy

scientific article published on 01 December 2018

Overcoming MET-dependent resistance to selective RET inhibition in patients with RET fusion-positive lung cancer by combining selpercatinib with crizotinib

scientific article published on 20 October 2020

Progresses toward precision medicine in RET-altered solid tumors

scientific article published on 14 July 2020

ROS1-dependent cancers - biology, diagnostics and therapeutics

scientific article published on 05 August 2020

Repotrectinib Exhibits Potent Antitumor Activity in Treatment-Naïve and Solvent-Front-Mutant ROS1-Rearranged Non-Small Cell Lung Cancer

scientific article published on 08 April 2020

Resistance to TRK inhibition mediated by convergent MAPK pathway activation

scientific article published on 12 August 2019

TRK Fusions Are Enriched in Cancers with Uncommon Histologies and the Absence of Canonical Driver Mutations

scientific article published on 23 December 2019

TRK xDFG mutations trigger a sensitivity switch from type I to II kinase inhibitors

scientific article published on 01 October 2020

The METeoric rise of MET in lung cancer

scientific article published on 05 September 2020

The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers

scientific article published on 18 March 2022

Therapeutic Implications of Germline Testing in Patients With Advanced Cancers

scientific article published on 16 June 2021

List of works by Alexander Drilon