List of works - Robert D Brook

"Stressed" About Air Pollution: Time for Personal Action

scientific article published on August 2017

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults. A report of the American College of Cardiology/American Heart Association Task Force on Clini

scientific article published on 27 January 2018

A Road Forward to Improve Public Health ⬇️

scientific article published on April 11, 2011

A joint ERS/ATS policy statement: what constitutes an adverse health effect of air pollution? An analytical framework

scientific article published on 11 January 2017

A novel homozygous ABCA1 variant in an asymptomatic man with profound hypoalphalipoproteinemia.

scientific article published on 21 April 2018

A review of blood pressure measurement protocols among hypertension trials: implications for "evidence-based" clinical practice

scientific article published on 09 July 2014

Acute blood pressure responses in healthy adults during controlled air pollution exposures

scientific article

Acute effects of ambient particulate matter on blood pressure: differential effects across urban communities

scientific article published on 9 March 2009

Acute response to a 2-minute isometric exercise test predicts the blood pressure-lowering efficacy of isometric resistance training in young adults

scientific article published on 27 September 2017

Air Pollution and Cardiometabolic Disease: An Update and Call for Clinical Trials

scientific article published on 01 December 2017

Air Pollution and Cardiovascular Disease: JACC State-of-the-Art Review

scientific article published on 01 October 2018

Air pollution and cardiac remodeling: a role for RhoA/Rho-kinase.

scientific article published on 13 March 2009

Air pollution and type 2 diabetes: mechanistic insights

scientific article

Air pollution exposure potentiates hypertension through reactive oxygen species-mediated activation of Rho/ROCK

scientific article

Air pollution: the "Heart" of the problem

scientific article

Air-Pollution and Cardiometabolic Diseases (AIRCMD): a prospective study investigating the impact of air pollution exposure and propensity for type II diabetes

scientific article

Ambient air pollution exaggerates adipose inflammation and insulin resistance in a mouse model of diet-induced obesity.

scientific article published on 19 January 2009

Ambient air pollution: an emerging risk factor for diabetes mellitus

scientific article published on June 2015

Ambient fine particulate matter and ozone exposures induce inflammation in epicardial and perirenal adipose tissues in rats fed a high fructose diet

scientific article published on 22 August 2013

Angiotensin receptor blockade improves vascular compliance in healthy normotensive elderly individuals: results from a randomized double-blind placebo-controlled trial

scientific article published on 01 November 2006

Attenuation of haemodynamic, metabolic and energy expenditure responses to isoproterenol in patients with hypertension

scientific article published in October 2004

Beta-blocker Therapy and Clinical Outcomes in Patients with Moderate COPD and Heightened Cardiovascular Risk: An Observational Sub-study of SUMMIT.

scientific article

Beyond Medications and Diet: Alternative Approaches to Lowering Blood Pressure: A Scientific Statement From the American Heart Association

scientific article

Blood pressure and vascular effects of leptin in humans

scientific article

Can personal exposures to higher nighttime and early-morning temperatures increase blood pressure?

scientific article published on 7 November 2011

Can what you breathe trigger a stroke within hours?: comment on "ambient air pollution and the risk of acute ischemic stroke".

scientific article published in February 2012

Cardiac Troponin I and Cardiovascular Risk in Patients With Chronic Obstructive Pulmonary Disease

scholarly article by Philip D Adamson et al published 4 September 2018 in Journal of the American College of Cardiology

Cardiovascular depression in rats exposed to inhaled particulate matter and ozone: effects of diet-induced metabolic syndrome

scientific article published on 29 October 2013

Cardiovascular impacts and micro-environmental exposure factors associated with continuous personal PM2.5 monitoring

scientific article published on 28 August 2013

Cardiovascular outcomes with an inhaled beta2-agonist/corticosteroid in patients with COPD at high cardiovascular risk

scientific article published on 17 April 2017

Chronic air pollution exposure and endothelial dysfunction: what you can't see--can harm you.

scientific article published on 24 October 2012

Chronic fine particulate matter exposure induces systemic vascular dysfunction via NADPH oxidase and TLR4 pathways

scientific article

Cigarette smoking and response to inhaled corticosteroids in COPD.

scientific article published on 18 January 2018

Climate and environmental triggers of acute myocardial infarction.

scientific article

Controlled exposure study of air pollution and T-wave alternans in volunteers without cardiovascular disease

scientific article

Coronary artery calcium in hypertension: a review

scientific article

DNA hypomethylation, ambient particulate matter, and increased blood pressure: findings from controlled human exposure experiments

scientific article published on 19 June 2013

Determinants of vascular function in patients with chronic gout

scientific article

Differences in blood pressure and vascular responses associated with ambient fine particulate matter exposures measured at the personal versus community level ⬇️

scientific article published on October 8, 2010

Does "hidden undercuffing" occur among obese patients? Effect of arm sizes and other predictors of the difference between wrist and upper arm blood pressures

scientific article published in February 2010

Effect of Fluticasone Furoate and Vilanterol on Exacerbations of Chronic Obstructive Pulmonary Disease in Patients with Moderate Airflow Obstruction.

scientific article

Effect of Particulate Matter Air Pollution on Cardiovascular Oxidative Stress Pathways

scientific article published on 30 October 2017

Effect of Portable Air Filtration Systems on Personal Exposure to Fine Particulate Matter and Blood Pressure Among Residents in a Low-Income Senior Facility: A Randomized Clinical Trial.

scientific article

Effect of carotid atherosclerosis screening on risk stratification during primary cardiovascular disease prevention

scientific article published on 01 April 2004

Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: a 2 × 2 factorial Mendelian randomization study

scientific article published on 11 March 2015

Effect of short-term weight loss on the metabolic syndrome and conduit vascular endothelial function in overweight adults

scientific article published in April 2004

Effects of concentrated fine ambient particles on rat plasma levels of asymmetric dimethylarginine

scientific article

Effects of urban fine particulate matter and ozone on HDL functionality

scientific article published on 24 May 2016

Endotoxin and β-1,3-d-Glucan in Concentrated Ambient Particles Induce Rapid Increase in Blood Pressure in Controlled Human Exposures

scientific article

Environmental stressors and cardio-metabolic disease: part I-epidemiologic evidence supporting a role for noise and air pollution and effects of mitigation strategies

scientific article

Environmental stressors and cardio-metabolic disease: part II-mechanistic insights.

scientific article

Exacerbations of Chronic Obstructive Pulmonary Disease and Cardiac Events: A Cohort Analysis.

scientific article published on 14 February 2018

Exploration of the Rapid Effects of Personal Fine Particulate Matter Exposure on Arterial Hemodynamics and Vascular Function during the Same Day ⬇️

scientific article published on May 1, 2011

Exploration of the composition and sources of urban fine particulate matter associated with same-day cardiovascular health effects in Dearborn, Michigan

scientific article

Extreme Air Pollution Conditions Adversely Affect Blood Pressure and Insulin Resistance: The Air Pollution and Cardiometabolic Disease Study

scientific article

Extreme Levels of Air Pollution Associated With Changes in Biomarkers of Atherosclerotic Plaque Vulnerability and Thrombogenicity in Healthy Adults.

scientific article published in March 2019

Extreme levels of ambient air pollution adversely impact cardiac and central aortic hemodynamics: the AIRCMD-China study

scientific article published on 28 September 2017

Fluticasone Furoate, Vilanterol and Lung Function Decline in Patients with Moderate COPD and Heightened Cardiovascular Risk.

scientific article published on 24 July 2017

Fluticasone furoate and vilanterol and survival in chronic obstructive pulmonary disease with heightened cardiovascular risk (SUMMIT): a double-blind randomised controlled trial.

scientific article published on 28 April 2016

Hemodynamic, autonomic, and vascular effects of exposure to coarse particulate matter air pollution from a rural location.

scientific article

Household Air Pollution from Solid Fuel Use

article

Hypertension and triglyceride catabolism: implications for the hemodynamic model of the metabolic syndrome

scientific article published in August 2003

Images in cardiovascular medicine: xanthomas triggered by bile acid sequestrants

scientific article published on 04 January 2008

Impact of pre-enrolment medication use on clinical outcomes in SUMMIT

Implementing new guidelines in the management of blood cholesterol

scientific article published on 22 February 2014

Incidence and Survival After In-Hospital Cardiopulmonary Resuscitation in Nonelderly Adults: US Experience, 2007 to 2012.

scientific article published in February 2017

Inhalation of fine particulate air pollution and ozone causes acute arterial vasoconstriction in healthy adults

scientific article (publication date: 2 April 2002)

Initial hypertension treatment: one combination fits most? ⬇️

scientific article published on March 1, 2011

Insights into the mechanisms and mediators of the effects of air pollution exposure on blood pressure and vascular function in healthy humans

scientific article

Interactive effects of the ACE DD polymorphism with the NOS III homozygous G849T (Glu298-->Asp) variant in determining endothelial function in coronary artery disease

scientific article published in January 2003

Intrasubject variability of radial artery flow-mediated dilatation in healthy subjects and implications for use in prospective clinical trials

scientific article published on 16 September 2005

Is acute high-dose secondhand smoke exposure always harmful to microvascular function in healthy adults?

scientific article published on January 2010

Isometric Handgrip as an Adjunct for Blood Pressure Control: a Primer for Clinicians

scientific article

LABA/ICS in COPD Patients with CV Disease or Risk: A Factorial Analysis of the SUMMIT Trial

scientific article published on 7 February 2018

Letter by Brook et al regarding article "Diesel exhaust inhalation causes vascular dysfunction and impaired endogenous fibrinolysis"

scientific article published on 01 June 2006

Lipoprotein (a): Perspectives from a lipid-referral program ⬇️

scientific article published on June 21, 2011

Long-term air pollution exposure and acceleration of atherosclerosis and vascular inflammation in an animal model

scientific article (publication date: 21 December 2005)

Medical Management of the Patient with Intermittent Claudication ⬇️

scientific article published on August 1, 2011

Medical nutrition therapy is the essential cornerstone for effective treatment of "refractory" severe hypertriglyceridemia regardless of pharmaceutical treatment: Evidence from a Lipid Management Program.

scientific article published on 9 April 2015

Mortality from myocardial infarction in chronic obstructive pulmonary disease: minding and mending the 'Gap'

scientific article published on 22 April 2015

Neutral effect on markers of heart failure, inflammation, endothelial activation and function, and vagal tone after high-dose HMG-CoA reductase inhibition in non-diabetic patients with non-ischemic cardiomyopathy and average low-density lipoprotein

scientific article published on 20 December 2005

Ozone-induced Metabolic Effects in Humans. Ieiunium, Conviviorum, aut Timor? (Fasting, Feasting, or Fear?).

scientific article published in June 2016

Particulate matter air pollution and atherosclerosis

scientific article published on September 2010

Particulate matter, air pollution, and blood pressure.

scientific article published in September 2009

Patient Awareness of the Risks for Heart Disease Posed by Air Pollution ⬇️

scientific article published on March 1, 2011

Personal black carbon exposure influences ambulatory blood pressure: air pollution and cardiometabolic disease (AIRCMD-China) study

scientific article published on 13 January 2014

Personal-level exposure to environmental temperature is a superior predictor of endothelial-dependent vasodilatation than outdoor-ambient level

scientific article

Personalizing your airspace and your health

article

Pneumonia risk with inhaled fluticasone furoate and vilanterol in COPD patients with moderate airflow limitation: The SUMMIT trial

scientific article published in August 2017

Potential effect of an apoprotein B-based algorithm on management of new patients with hypertriglyceridemia referred to a specialty lipid clinic.

scientific article

Potential effects on clinical management of treatment algorithms on the basis of apolipoprotein-B/A-1 and total/high-density lipoprotein-cholesterol ratios ⬇️

scientific article published on February 12, 2011

Pulse Wave Velocity in Chronic Obstructive Pulmonary Disease and the Impact of Inhaled Therapy (SUMMIT): A Randomized Double-blind Clinical Trial

scientific article published on 04 February 2020

Rapid-onset endothelial dysfunction with adriamycin: evidence for a dysfunctional nitric oxide synthase ⬇️

scientific article published on May 1, 2003

Reduced metabolic insulin sensitivity following sub-acute exposures to low levels of ambient fine particulate matter air pollution.

scientific article

Reported obstructive sleep apnea does not diminish the cardiometabolic health benefits from a comprehensive lifestyle intervention program

article

Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association

scientific article published in November 2018

Response to Call for a re-evaluation of the American Heart Association's standpoint concerning device-guided slow breathing using the RESPeRATE device.

scientific article published in October 2013

Response to comment on “beyond medications and diet: alternative approaches to lowering blood pressure: a scientific statement from the American Heart Association”

scientific article published on 01 January 2014

Secondary Causes of Dyslipidemia ⬇️

scientific article published on 02 June 2012

Short-Term Blood Pressure Responses to Ambient Fine Particulate Matter Exposures at the Extremes of Global Air Pollution Concentrations

scientific article published on 2 February 2018

THE INDOOR-OUTDOOR AIR-POLLUTION CONTINUUM AND THE BURDEN OF CARDIOVASCULAR DISEASE: AN OPPORTUNITY FOR IMPROVING GLOBAL HEALTH.

scientific article

The Effect of Air Pollution on Spatial Dispersion of Myocardial Repolarization in Healthy Human Volunteers ⬇️

scientific article published on January 11, 2011

The Global Threat of Outdoor Ambient Air Pollution to Cardiovascular Health: Time for Intervention

scientific article published on 22 February 2017

The Study to Understand Mortality and Morbidity in COPD (SUMMIT) study protocol

scientific article published on 27 September 2012

The characteristics of coarse particulate matter air pollution associated with alterations in blood pressure and heart rate during controlled exposures

scientific article

The effect of acute exposure to coarse particulate matter air pollution in a rural location on circulating endothelial progenitor cells: results from a randomized controlled study

scientific article

The peroxisome proliferator activated receptor-γ pioglitazone improves vascular function and decreases disease activity in patients with rheumatoid arthritis

scientific article

The relationship between diabetes mellitus and traffic-related air pollution

scientific article published on 01 January 2008

Treating Mixed Hyperlipidemia and the Atherogenic Lipid Phenotype for Prevention of Cardiovascular Events ⬇️

scientific article published on October 1, 2010

Understanding Air Pollution and Cardiovascular Diseases: Is It Preventable?

scientific article

Usefulness of low-density lipoprotein particle size measurement in cardiovascular disease prevention

scientific article published in November 2005

Valsartan Improves Insulin Sensitivity without Altering Vascular Function in Healthy Overweight Adults without the Metabolic Syndrome

scientific article

“Environmental Hypertensionology” The Effects of Environmental Factors on Blood Pressure in Clinical Practice and Research ⬇️

scientific article published on October 18, 2011

List of works by Robert D Brook

"Stressed" About Air Pollution: Time for Personal Action

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults. A report of the American College of Cardiology/American Heart Association Task Force on Clini

A Road Forward to Improve Public Health ⬇️

A joint ERS/ATS policy statement: what constitutes an adverse health effect of air pollution? An analytical framework

A novel homozygous ABCA1 variant in an asymptomatic man with profound hypoalphalipoproteinemia.

A review of blood pressure measurement protocols among hypertension trials: implications for "evidence-based" clinical practice

Acute blood pressure responses in healthy adults during controlled air pollution exposures

Acute effects of ambient particulate matter on blood pressure: differential effects across urban communities

Acute response to a 2-minute isometric exercise test predicts the blood pressure-lowering efficacy of isometric resistance training in young adults

Air Pollution and Cardiometabolic Disease: An Update and Call for Clinical Trials

Air Pollution and Cardiovascular Disease: JACC State-of-the-Art Review

Air pollution and cardiac remodeling: a role for RhoA/Rho-kinase.

Air pollution and type 2 diabetes: mechanistic insights

Air pollution exposure potentiates hypertension through reactive oxygen species-mediated activation of Rho/ROCK

Air pollution: the "Heart" of the problem

Air-Pollution and Cardiometabolic Diseases (AIRCMD): a prospective study investigating the impact of air pollution exposure and propensity for type II diabetes

Ambient air pollution exaggerates adipose inflammation and insulin resistance in a mouse model of diet-induced obesity.

Ambient air pollution: an emerging risk factor for diabetes mellitus

Ambient fine particulate matter and ozone exposures induce inflammation in epicardial and perirenal adipose tissues in rats fed a high fructose diet

Angiotensin receptor blockade improves vascular compliance in healthy normotensive elderly individuals: results from a randomized double-blind placebo-controlled trial

Attenuation of haemodynamic, metabolic and energy expenditure responses to isoproterenol in patients with hypertension

Beta-blocker Therapy and Clinical Outcomes in Patients with Moderate COPD and Heightened Cardiovascular Risk: An Observational Sub-study of SUMMIT.

Beyond Medications and Diet: Alternative Approaches to Lowering Blood Pressure: A Scientific Statement From the American Heart Association

Blood pressure and vascular effects of leptin in humans

Can personal exposures to higher nighttime and early-morning temperatures increase blood pressure?

Can what you breathe trigger a stroke within hours?: comment on "ambient air pollution and the risk of acute ischemic stroke".

Cardiac Troponin I and Cardiovascular Risk in Patients With Chronic Obstructive Pulmonary Disease

Cardiovascular depression in rats exposed to inhaled particulate matter and ozone: effects of diet-induced metabolic syndrome

Cardiovascular impacts and micro-environmental exposure factors associated with continuous personal PM2.5 monitoring

Cardiovascular outcomes with an inhaled beta2-agonist/corticosteroid in patients with COPD at high cardiovascular risk

Chronic air pollution exposure and endothelial dysfunction: what you can't see--can harm you.

Chronic fine particulate matter exposure induces systemic vascular dysfunction via NADPH oxidase and TLR4 pathways

Cigarette smoking and response to inhaled corticosteroids in COPD.

Climate and environmental triggers of acute myocardial infarction.

Controlled exposure study of air pollution and T-wave alternans in volunteers without cardiovascular disease

Coronary artery calcium in hypertension: a review

DNA hypomethylation, ambient particulate matter, and increased blood pressure: findings from controlled human exposure experiments

Determinants of vascular function in patients with chronic gout

Differences in blood pressure and vascular responses associated with ambient fine particulate matter exposures measured at the personal versus community level ⬇️

Does "hidden undercuffing" occur among obese patients? Effect of arm sizes and other predictors of the difference between wrist and upper arm blood pressures

Effect of Fluticasone Furoate and Vilanterol on Exacerbations of Chronic Obstructive Pulmonary Disease in Patients with Moderate Airflow Obstruction.

Effect of Particulate Matter Air Pollution on Cardiovascular Oxidative Stress Pathways

Effect of Portable Air Filtration Systems on Personal Exposure to Fine Particulate Matter and Blood Pressure Among Residents in a Low-Income Senior Facility: A Randomized Clinical Trial.

Effect of carotid atherosclerosis screening on risk stratification during primary cardiovascular disease prevention

Effect of naturally random allocation to lower low-density lipoprotein cholesterol on the risk of coronary heart disease mediated by polymorphisms in NPC1L1, HMGCR, or both: a 2 × 2 factorial Mendelian randomization study

Effect of short-term weight loss on the metabolic syndrome and conduit vascular endothelial function in overweight adults

Effects of concentrated fine ambient particles on rat plasma levels of asymmetric dimethylarginine

Effects of urban fine particulate matter and ozone on HDL functionality

Endotoxin and β-1,3-d-Glucan in Concentrated Ambient Particles Induce Rapid Increase in Blood Pressure in Controlled Human Exposures

Environmental stressors and cardio-metabolic disease: part I-epidemiologic evidence supporting a role for noise and air pollution and effects of mitigation strategies

Environmental stressors and cardio-metabolic disease: part II-mechanistic insights.

Exacerbations of Chronic Obstructive Pulmonary Disease and Cardiac Events: A Cohort Analysis.

Exploration of the Rapid Effects of Personal Fine Particulate Matter Exposure on Arterial Hemodynamics and Vascular Function during the Same Day ⬇️

Exploration of the composition and sources of urban fine particulate matter associated with same-day cardiovascular health effects in Dearborn, Michigan

Extreme Air Pollution Conditions Adversely Affect Blood Pressure and Insulin Resistance: The Air Pollution and Cardiometabolic Disease Study

Extreme Levels of Air Pollution Associated With Changes in Biomarkers of Atherosclerotic Plaque Vulnerability and Thrombogenicity in Healthy Adults.

Extreme levels of ambient air pollution adversely impact cardiac and central aortic hemodynamics: the AIRCMD-China study

Fluticasone Furoate, Vilanterol and Lung Function Decline in Patients with Moderate COPD and Heightened Cardiovascular Risk.

Fluticasone furoate and vilanterol and survival in chronic obstructive pulmonary disease with heightened cardiovascular risk (SUMMIT): a double-blind randomised controlled trial.

Hemodynamic, autonomic, and vascular effects of exposure to coarse particulate matter air pollution from a rural location.

Household Air Pollution from Solid Fuel Use

Hypertension and triglyceride catabolism: implications for the hemodynamic model of the metabolic syndrome

Images in cardiovascular medicine: xanthomas triggered by bile acid sequestrants

Impact of pre-enrolment medication use on clinical outcomes in SUMMIT

Implementing new guidelines in the management of blood cholesterol

Incidence and Survival After In-Hospital Cardiopulmonary Resuscitation in Nonelderly Adults: US Experience, 2007 to 2012.

Inhalation of fine particulate air pollution and ozone causes acute arterial vasoconstriction in healthy adults

Initial hypertension treatment: one combination fits most? ⬇️

Insights into the mechanisms and mediators of the effects of air pollution exposure on blood pressure and vascular function in healthy humans

Interactive effects of the ACE DD polymorphism with the NOS III homozygous G849T (Glu298-->Asp) variant in determining endothelial function in coronary artery disease

Intrasubject variability of radial artery flow-mediated dilatation in healthy subjects and implications for use in prospective clinical trials

Is acute high-dose secondhand smoke exposure always harmful to microvascular function in healthy adults?

Isometric Handgrip as an Adjunct for Blood Pressure Control: a Primer for Clinicians

LABA/ICS in COPD Patients with CV Disease or Risk: A Factorial Analysis of the SUMMIT Trial

Letter by Brook et al regarding article "Diesel exhaust inhalation causes vascular dysfunction and impaired endogenous fibrinolysis"

Lipoprotein (a): Perspectives from a lipid-referral program ⬇️

Long-term air pollution exposure and acceleration of atherosclerosis and vascular inflammation in an animal model

Medical Management of the Patient with Intermittent Claudication ⬇️

Medical nutrition therapy is the essential cornerstone for effective treatment of "refractory" severe hypertriglyceridemia regardless of pharmaceutical treatment: Evidence from a Lipid Management Program.