List of works - Lei Liu

Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion.

scientific article published on March 2015

CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death

scientific journal article

Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5

scientific journal article

Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death

scientific journal article

Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network.

scientific article

Celastrol Attenuates Cadmium-Induced Neuronal Apoptosis via Inhibiting Ca2+ -CaMKII-Dependent Akt/mTOR Pathway

scientific article published on 27 November 2016

Celastrol prevents cadmium-induced neuronal cell death by blocking reactive oxygen species-mediated mammalian target of rapamycin pathway

scientific article published on 20 October 2016

Crosstalk between Ca2+ signaling and mitochondrial H2O2 is required for rotenone inhibition of mTOR signaling pathway leading to neuronal apoptosis.

scientific article published on 03 February 2016

Cryptotanshinone activates p38/JNK and inhibits Erk1/2 leading to caspase-independent cell death in tumor cells

scientific article

Curcumin disrupts the Mammalian target of rapamycin-raptor complex.

scientific article

Curcumin inhibits protein phosphatases 2A and 5, leading to activation of mitogen-activated protein kinases and death in tumor cells.

scientific article published on 31 January 2012

Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells

scientific article

Hydrogen peroxide inhibits mTOR signaling by activation of AMPKalpha leading to apoptosis of neuronal cells

scientific article

Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway

scientific journal article

MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis

scientific article published on 16 November 2007

Rapamycin ameliorates cadmium-induced activation of MAPK pathway and neuronal apoptosis by preventing mitochondrial ROS inactivation of PP2A.

scientific article published on 21 January 2016

Rapamycin inhibits IGF-1 stimulated cell motility through PP2A pathway

scientific article

Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity.

scientific article

Rapamycin inhibits lymphatic endothelial cell tube formation by downregulating vascular endothelial growth factor receptor 3 protein expression.

scientific article published in March 2012

Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis

scientific article

The antitumor activity of the fungicide ciclopirox

scientific article published on November 2010

List of works by Lei Liu

Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion.

CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death

Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5

Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death

Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network.

Celastrol Attenuates Cadmium-Induced Neuronal Apoptosis via Inhibiting Ca2+ -CaMKII-Dependent Akt/mTOR Pathway

Celastrol prevents cadmium-induced neuronal cell death by blocking reactive oxygen species-mediated mammalian target of rapamycin pathway

Crosstalk between Ca2+ signaling and mitochondrial H2O2 is required for rotenone inhibition of mTOR signaling pathway leading to neuronal apoptosis.

Cryptotanshinone activates p38/JNK and inhibits Erk1/2 leading to caspase-independent cell death in tumor cells

Curcumin disrupts the Mammalian target of rapamycin-raptor complex.

Curcumin inhibits protein phosphatases 2A and 5, leading to activation of mitogen-activated protein kinases and death in tumor cells.

Curcumin inhibits the mammalian target of rapamycin-mediated signaling pathways in cancer cells

Hydrogen peroxide inhibits mTOR signaling by activation of AMPKalpha leading to apoptosis of neuronal cells

Hydrogen peroxide-induced neuronal apoptosis is associated with inhibition of protein phosphatase 2A and 5, leading to activation of MAPK pathway

MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis

Rapamycin ameliorates cadmium-induced activation of MAPK pathway and neuronal apoptosis by preventing mitochondrial ROS inactivation of PP2A.

Rapamycin inhibits IGF-1 stimulated cell motility through PP2A pathway

Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity.

Rapamycin inhibits lymphatic endothelial cell tube formation by downregulating vascular endothelial growth factor receptor 3 protein expression.

Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis

The antitumor activity of the fungicide ciclopirox