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List of works by Susan Baserga

, a candidate gene for isolated congenital asplenia, is required for pre-rRNA processing and spleen formation in

article

A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism ⬇️

scientific article

A conserved deubiquitinating enzyme controls cell growth by regulating RNA polymerase I stability.

scientific article

A dimeric structure for archaeal box C/D small ribonucleoproteins

scientific article

A direct interaction between the Utp6 half-a-tetratricopeptide repeat domain and a specific peptide in Utp21 is essential for efficient pre-rRNA processing.

scientific article

A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization.

scientific article

A high-throughput assay for directly monitoring nucleolar rRNA biogenesis

scientific article published on 26 January 2022

A high-throughput assay for directly monitoring nucleolar rRNA biogenesis

scientific article published on 19 July 2021

A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis

scientific article

A nucleolar protein related to ribosomal protein L7 is required for an early step in large ribosomal subunit biogenesis

scientific article

A protein interaction map of the LSU processome

scientific article

A structural model for the HAT domain of Utp6 incorporating bioinformatics and genetics

scientific article published on 10 June 2009

Aberrant splicing contributes to severe α-spectrin-linked congenital hemolytic anemia

scientific article published on 30 April 2019

An intact Box C sequence in the U3 snRNA is required for binding of fibrillarin, the protein common to the major family of nucleolar snRNPs ⬇️

scientific article published on September 1, 1991

An unexpected, conserved element of the U3 snoRNA is required for Mpp10p association

scientific article

Assembling a Protein-Protein Interaction Map of the SSU Processome from Existing Datasets ⬇️

scientific article published on March 10, 2011

Beta-globin nonsense mutation: deficient accumulation of mRNA occurs despite normal cytoplasmic stability

scientific article published on April 1992

Biallelic splicing variants in the nucleolar 60S assembly factor RBM28 cause the ribosomopathy ANE syndrome

scientific article published on 11 May 2021

Box C/D sRNA stem ends act as stabilizing anchors for box C/D di-sRNPs.

scientific article published on 24 June 2016

Changes in RNA polymerase II in a cell cycle-specific temperature-sensitive mutant of hamster cells.

scientific article published in April 1980

Components of an interdependent unit within the SSU processome regulate and mediate its activity.

scientific article

Comprehensive mutational analysis of yeast DEXD/H box RNA helicases involved in large ribosomal subunit biogenesis

scientific article

Comprehensive mutational analysis of yeast DEXD/H box RNA helicases required for small ribosomal subunit synthesis

scientific article

Crosstalk between the nucleolus and the DNA damage response.

scientific article published on 23 January 2017

Crosstalk in gene expression: coupling and co-regulation of rDNA transcription, pre-ribosome assembly and pre-rRNA processing

scientific article

Delayed rRNA processing results in significant ribosome biogenesis and functional defects

scientific article

Detecting small mutations in expressed genes by a combination of S1 nuclease and RNase A.

scientific article published on September 1988

Determinants of mammalian nucleolar architecture

scientific article

Discovery of novel microRNA regulators of ribosome biogenesis

scientific article published on 17 February 2023

Dissecting the role of conserved box C/D sRNA sequences in di-sRNP assembly and function

scientific article

Distinct molecular signals for nuclear import of the nucleolar snRNA, U3.

scientific article published in June 1992

Diverse Regulators of Human Ribosome Biogenesis Discovered by Changes in Nucleolar Number.

scientific article published in February 2018

Driving nucleolar assembly

scientific article published on February 2014

Ella Clay Wakeman: Yale School of Medicine, 1921.

scientific article published on September 1995

Emerging Roles for the Nucleolus 2017.

scientific article

Expression of ribosomopathy genes during Xenopus tropicalis embryogenesis

scientific article

Fanconi anemia protein FANCI functions in ribosome biogenesis

scientific article published on 28 January 2019

Fibrillarin and other snoRNP proteins are targets of autoantibodies in xenobiotic-induced autoimmunity

scientific article

Fibrillarin-associated box C/D small nucleolar RNAs in Trypanosoma brucei. Sequence conservation and implications for 2'-O-ribose methylation of rRNA

scientific article (publication date: 12 May 2000)

Functional separation of pre-rRNA processing steps revealed by truncation of the U3 small nucleolar ribonucleoprotein component, Mpp10 ⬇️

scientific article published on December 9, 1997

Genetics. Mysterious ribosomopathies

scientific article

Human Nop5/Nop58 is a component common to the box C/D small nucleolar ribonucleoproteins

scientific article

Human Nucleolar Protein 7 (NOL7) is required for pre-rRNA transcription and pre-18S rRNA processing

preprint

Human diseases of the SSU processome

scientific article

Human nucleolar protein 7 (NOL7) is required for early pre-rRNA accumulation and pre-18S rRNA processing

scientific article published in January 2023

Human pre-60S assembly factors link rRNA transcription to pre-rRNA processing

scientific article published on 2 November 2022

Human pre-60S assembly factors link rRNA transcription to pre-rRNA processing

preprint

Imp3p and Imp4p, two specific components of the U3 small nucleolar ribonucleoprotein that are essential for pre-18S rRNA processing

scientific article

In vivo approaches to dissecting the function of RNA helicases in eukaryotic ribosome assembly

scientific article published on January 2012

Increased numbers of nucleoli in a genome-wide RNAi screen reveal proteins that link the cell cycle to RNA polymerase I transcription

scientific article published on 10 March 2021

Long noncoding RNAs as sinks in Prader-Willi syndrome

scientific article published on October 2012

M Phase Phosphoprotein 10 Is a Human U3 Small Nucleolar Ribonucleoprotein Component ⬇️

scientific article published on February 1, 1998

Making Ribosomes: Pre-rRNA Transcription and Processing

Metabolism of non-translatable globin mRNAs arising from premature translation termination codons

scientific article published on 01 January 1990

Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis.

scientific article published in May 2018

MicroRNAs and long non-coding RNAs as novel regulators of ribosome biogenesis

scientific article published on 08 April 2020

Mpp10p, a U3 Small Nucleolar Ribonucleoprotein Component Required for Pre-18S rRNA Processing in Yeast ⬇️

scientific article published on October 1, 1997

Mpp10p, a new protein component of the U3 snoRNP required for processing of 18S rRNA precursors ⬇️

scientific article published on January 1, 1997

Mutations in KDSR Cause Recessive Progressive Symmetric Erythrokeratoderma

scientific article published on June 2017

NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing

scientific article

Nonsense mutations in the human beta-globin gene affect mRNA metabolism ⬇️

scientific article published on April 1, 1988

Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA.

scientific article published on 11 October 2016

Nop9 recognizes structured and single-stranded RNA elements of pre-ribosomal RNA

scientific article published on 05 May 2020

Paired Box 9 (PAX9), the RNA polymerase II transcription factor, regulates human ribosome biogenesis and craniofacial development

scientific article published on 19 August 2020

Polyadenylation of a human mitochondrial ribosomal RNA transcript detected by molecular cloning

scientific article published in January 1985

Pre-18S ribosomal RNA is structurally compacted into the SSU processome prior to being cleaved from nascent transcripts in Saccharomyces cerevisiae

scientific article

Probing the mechanisms underlying human diseases in making ribosomes

scientific article published on August 2016

Probing the yeast proteome for RNA-processing factors

scientific article

RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components

scientific article

Ribonucleoprotein multimers and their functions

scientific article

Ribonucleoproteins in archaeal pre-rRNA processing and modification.

scientific article published on 10 March 2013

Ribosome biogenesis in the yeast Saccharomyces cerevisiae

scientific article

Ribosome biogenesis is sensed at the Start cell cycle checkpoint

scientific article

Ribosome biogenesis: of knobs and RNA processing

scientific article published on May 2004

Ribosomes Need Straight A's to Sleep

scientific article published in May 2017

Ribosomopathies: Old Concepts, New Controversies

scientific article published on 31 July 2019

Survival motor neuron protein in the nucleolus of mammalian neurons

scientific article

The C-terminus of Utp4, mutated in childhood cirrhosis, is essential for ribosome biogenesis.

scientific article

The Contributions of the Ribosome Biogenesis Protein Utp5/WDR43 to Craniofacial Development

scientific article published on 24 May 2016

The DEAD-box RNA helicase-like Utp25 is an SSU processome component

scientific article

The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation ⬇️

scientific article

The SSU processome interactome in Saccharomyces cerevisiae reveals novel protein subcomplexes

scientific article

The U14 snoRNA is required for 2'-O-methylation of the pre-18S rRNA in Xenopus oocytes ⬇️

scientific article published on February 1, 1998

The U18 snRNA is not essential for pre-rRNA processing in Xenopus laevis.

scientific article published on April 1996

The box C/D sRNP dimeric architecture is conserved across domain Archaea

scientific article

The coiled-coil domain of the Nop56/58 core protein is dispensable for sRNP assembly but is critical for archaeal box C/D sRNP-guided nucleotide methylation

scientific article published on 6 April 2006

The cytidine deaminase APOBEC3A is required for large ribosomal subunit biogenesis

scientific article published on 20 February 2023

The early years of coeducation at the Yale University School of Medicine.

scientific article published on May 1980

The genes for small nucleolar RNAs in Trypanosoma brucei are organized in clusters and are transcribed as a polycistronic RNA.

scientific article published on August 2000

The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes

scientific article

The initial U3 snoRNA:pre-rRNA base pairing interaction required for pre-18S rRNA folding revealed by in vivo chemical probing ⬇️

scientific article published on February 23, 2011

The long unwinding road of RNA helicases

scientific article published on August 2007

The molecular basis for ANE syndrome revealed by the large ribosomal subunit processome interactome.

scientific article published on 14 April 2016

The nucleolar protein Esf2 interacts directly with the DExD/H box RNA helicase, Dbp8, to stimulate ATP hydrolysis

scientific article

The pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma

scientific article

The putative NTPase Fap7 mediates cytoplasmic 20S pre-rRNA processing through a direct interaction with Rps14.

scientific article

The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus

scientific article published on 10 March 2015

The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis

scientific article

The small subunit processome in ribosome biogenesis—progress and prospects ⬇️

scientific article published on January 1, 2011

The small subunit processome is required for cell cycle progression at G1.

scientific article published on 08 September 2004

The small-subunit processome is a ribosome assembly intermediate

scientific article

Three pseudogenes for human U13 snRNA belong to class III ⬇️

scientific article published on November 15, 1991

Tissue specific roles for the ribosome biogenesis factor Wdr43 in zebrafish development

scientific article published on 30 January 2014

Two-hybrid Mpp10p interaction-defective Imp4 proteins are not interaction defective in vivo but do confer specific pre-rRNA processing defects in Saccharomyces cerevisiae

scientific article published on 27 February 2004

U8 variants on the brain: a small nucleolar RNA and human disease

scientific article published in 2022

When ribosomes go bad: diseases of ribosome biogenesis

scientific article

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