List of works - Susan Baserga

A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis

scientific article

Ribosome biogenesis in the yeast Saccharomyces cerevisiae

scientific article

Pre-18S ribosomal RNA is structurally compacted into the SSU processome prior to being cleaved from nascent transcripts in Saccharomyces cerevisiae

scientific article

RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components

scientific article

Nonsense mutations in the human beta-globin gene affect mRNA metabolism

scientific article published on April 1, 1988

Ribosome biogenesis: of knobs and RNA processing

scientific article published on May 2004

The small-subunit processome is a ribosome assembly intermediate

scientific article

The long unwinding road of RNA helicases

scientific article published on August 2007

Imp3p and Imp4p, two specific components of the U3 small nucleolar ribonucleoprotein that are essential for pre-18S rRNA processing

scientific article

When ribosomes go bad: diseases of ribosome biogenesis

scientific article published on January 11, 2010

The small subunit processome in ribosome biogenesis—progress and prospects

scientific article published on January 1, 2011

Mpp10p, a U3 Small Nucleolar Ribonucleoprotein Component Required for Pre-18S rRNA Processing in Yeast

scientific article published on October 1, 1997

An intact Box C sequence in the U3 snRNA is required for binding of fibrillarin, the protein common to the major family of nucleolar snRNPs

scientific article published on September 1, 1991

Genetics. Mysterious ribosomopathies

scientific article

Beta-globin nonsense mutation: deficient accumulation of mRNA occurs despite normal cytoplasmic stability

scientific article published on April 1992

The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis

scientific article

Crosstalk in gene expression: coupling and co-regulation of rDNA transcription, pre-ribosome assembly and pre-rRNA processing

scientific article

A protein interaction map of the LSU processome

scientific article

Ribosome biogenesis is sensed at the Start cell cycle checkpoint

scientific article

The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation

scientific article

The putative NTPase Fap7 mediates cytoplasmic 20S pre-rRNA processing through a direct interaction with Rps14.

scientific article

The SSU processome interactome in Saccharomyces cerevisiae reveals novel protein subcomplexes

scientific article published on October 20, 2017

Components of an interdependent unit within the SSU processome regulate and mediate its activity

scientific article

The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes

scientific article

A nucleolar protein related to ribosomal protein L7 is required for an early step in large ribosomal subunit biogenesis

scientific article

Human Nop5/Nop58 is a component common to the box C/D small nucleolar ribonucleoproteins

scientific article

The initial U3 snoRNA:pre-rRNA base pairing interaction required for pre-18S rRNA folding revealed by in vivo chemical probing

scientific article published on February 23, 2011

The DEAD-box RNA helicase-like Utp25 is an SSU processome component

scientific article

The small subunit processome is required for cell cycle progression at G1.

scientific article published on 08 September 2004

Functional separation of pre-rRNA processing steps revealed by truncation of the U3 small nucleolar ribonucleoprotein component, Mpp10

scientific article published on December 9, 1997

NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing

scientific article

Comprehensive mutational analysis of yeast DEXD/H box RNA helicases involved in large ribosomal subunit biogenesis

scientific article

Distinct molecular signals for nuclear import of the nucleolar snRNA, U3.

scientific article published in June 1992

A direct interaction between the Utp6 half-a-tetratricopeptide repeat domain and a specific peptide in Utp21 is essential for efficient pre-rRNA processing.

scientific article

A dimeric structure for archaeal box C/D small ribonucleoproteins

scientific article

M Phase Phosphoprotein 10 Is a Human U3 Small Nucleolar Ribonucleoprotein Component

scientific article published on February 1, 1998

The nucleolar protein Esf2 interacts directly with the DExD/H box RNA helicase, Dbp8, to stimulate ATP hydrolysis

scientific article

Comprehensive mutational analysis of yeast DEXD/H box RNA helicases required for small ribosomal subunit synthesis

scientific article

The C-terminus of Utp4, mutated in childhood cirrhosis, is essential for ribosome biogenesis.

scientific article

Human diseases of the SSU processome

scientific article

A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism

scientific article

Fibrillarin-associated box C/D small nucleolar RNAs in Trypanosoma brucei. Sequence conservation and implications for 2'-O-ribose methylation of rRNA

scientific article (publication date: 12 May 2000)

A conserved deubiquitinating enzyme controls cell growth by regulating RNA polymerase I stability.

scientific article

The coiled-coil domain of the Nop56/58 core protein is dispensable for sRNP assembly but is critical for archaeal box C/D sRNP-guided nucleotide methylation

scientific article published on 6 April 2006

The genes for small nucleolar RNAs in Trypanosoma brucei are organized in clusters and are transcribed as a polycistronic RNA.

scientific article published on August 2000

Determinants of mammalian nucleolar architecture

scientific article published on February 12, 2015

The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus

scientific article published on 10 March 2015

Tissue specific roles for the ribosome biogenesis factor Wdr43 in zebrafish development

scientific article published on 30 January 2014

Delayed rRNA processing results in significant ribosome biogenesis and functional defects

scientific article

A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization.

scientific article

List of works by Susan Baserga

A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis

Ribosome biogenesis in the yeast Saccharomyces cerevisiae

Pre-18S ribosomal RNA is structurally compacted into the SSU processome prior to being cleaved from nascent transcripts in Saccharomyces cerevisiae

RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components

Nonsense mutations in the human beta-globin gene affect mRNA metabolism

Ribosome biogenesis: of knobs and RNA processing

The small-subunit processome is a ribosome assembly intermediate

The long unwinding road of RNA helicases

Imp3p and Imp4p, two specific components of the U3 small nucleolar ribonucleoprotein that are essential for pre-18S rRNA processing

When ribosomes go bad: diseases of ribosome biogenesis

The small subunit processome in ribosome biogenesis—progress and prospects

Mpp10p, a U3 Small Nucleolar Ribonucleoprotein Component Required for Pre-18S rRNA Processing in Yeast

An intact Box C sequence in the U3 snRNA is required for binding of fibrillarin, the protein common to the major family of nucleolar snRNPs

Genetics. Mysterious ribosomopathies

Beta-globin nonsense mutation: deficient accumulation of mRNA occurs despite normal cytoplasmic stability

The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis

Crosstalk in gene expression: coupling and co-regulation of rDNA transcription, pre-ribosome assembly and pre-rRNA processing

A protein interaction map of the LSU processome

Ribosome biogenesis is sensed at the Start cell cycle checkpoint

The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation

The putative NTPase Fap7 mediates cytoplasmic 20S pre-rRNA processing through a direct interaction with Rps14.

The SSU processome interactome in Saccharomyces cerevisiae reveals novel protein subcomplexes

Components of an interdependent unit within the SSU processome regulate and mediate its activity

The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes

A nucleolar protein related to ribosomal protein L7 is required for an early step in large ribosomal subunit biogenesis

Human Nop5/Nop58 is a component common to the box C/D small nucleolar ribonucleoproteins

The initial U3 snoRNA:pre-rRNA base pairing interaction required for pre-18S rRNA folding revealed by in vivo chemical probing

The DEAD-box RNA helicase-like Utp25 is an SSU processome component

The small subunit processome is required for cell cycle progression at G1.

Functional separation of pre-rRNA processing steps revealed by truncation of the U3 small nucleolar ribonucleoprotein component, Mpp10

NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing

Comprehensive mutational analysis of yeast DEXD/H box RNA helicases involved in large ribosomal subunit biogenesis

Distinct molecular signals for nuclear import of the nucleolar snRNA, U3.

A direct interaction between the Utp6 half-a-tetratricopeptide repeat domain and a specific peptide in Utp21 is essential for efficient pre-rRNA processing.

A dimeric structure for archaeal box C/D small ribonucleoproteins

M Phase Phosphoprotein 10 Is a Human U3 Small Nucleolar Ribonucleoprotein Component

The nucleolar protein Esf2 interacts directly with the DExD/H box RNA helicase, Dbp8, to stimulate ATP hydrolysis

Comprehensive mutational analysis of yeast DEXD/H box RNA helicases required for small ribosomal subunit synthesis

The C-terminus of Utp4, mutated in childhood cirrhosis, is essential for ribosome biogenesis.

Human diseases of the SSU processome

A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism

Fibrillarin-associated box C/D small nucleolar RNAs in Trypanosoma brucei. Sequence conservation and implications for 2'-O-ribose methylation of rRNA

A conserved deubiquitinating enzyme controls cell growth by regulating RNA polymerase I stability.

The coiled-coil domain of the Nop56/58 core protein is dispensable for sRNP assembly but is critical for archaeal box C/D sRNP-guided nucleotide methylation

The genes for small nucleolar RNAs in Trypanosoma brucei are organized in clusters and are transcribed as a polycistronic RNA.

Determinants of mammalian nucleolar architecture

The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus

Tissue specific roles for the ribosome biogenesis factor Wdr43 in zebrafish development

Delayed rRNA processing results in significant ribosome biogenesis and functional defects

A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization.