List of works - Christopher S Fry

2,000 Steps/Day Does Not Fully Protect Skeletal Muscle Health in Older Adults During Bed Rest

scientific article published on 20 January 2019

A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults.

scientific article

ACL injury reduces satellite cell abundance and promotes fibrogenic cell expansion within skeletal muscle

scientific article published on 9 December 2016

Addition of carbohydrate or alanine to an essential amino acid mixture does not enhance human skeletal muscle protein anabolism

scientific article published on 23 January 2013

Aged Muscle Demonstrates Fiber-Type Adaptations in Response to Mechanical Overload, in the Absence of Myofiber Hypertrophy, Independent of Satellite Cell Abundance.

scientific article published on 15 April 2015

Aging differentially affects human skeletal muscle microRNA expression at rest and after an anabolic stimulus of resistance exercise and essential amino acids

scientific article published on 30 September 2008

Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis.

scientific article

Aging-related effects of bed rest followed by eccentric exercise rehabilitation on skeletal muscle macrophages and insulin sensitivity

scientific article published on 10 July 2017

Altered satellite cell dynamics accompany skeletal muscle atrophy during chronic illness, disuse, and aging

scientific article published on 8 August 2017

An increase in essential amino acid availability upregulates amino acid transporter expression in human skeletal muscle

scientific article

An obesogenic maternal environment impairs mouse growth patterns, satellite cell activation and markers of post-natal myogenesis

scientific article published on 21 September 2020

Anterior Cruciate Ligament Tear Promotes Skeletal Muscle Myostatin Expression, Fibrogenic Cell Expansion, and a Decline in Muscle Quality

scientific article published on 17 April 2019

Automated fiber-type-specific cross-sectional area assessment and myonuclei counting in skeletal muscle

scientific article published on 03 October 2013

Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults.

scientific article

Blood flow restriction exercise stimulates mTORC1 signaling and muscle protein synthesis in older men

scientific article

Chronic doxorubicin administration impacts satellite cell and capillary abundance in a muscle-specific manner

scientific article published on 01 April 2019

Chronic paraplegia-induced muscle atrophy downregulates the mTOR/S6K1 signaling pathway

scientific journal article

Countering disuse atrophy in older adults with low volume leucine supplementation

scientific article published on 19 March 2020

Cycle training modulates satellite cell and transcriptional responses to a bout of resistance exercise

scientific article published on September 2016

Effect of Aerobic Exercise Training and Essential Amino Acid Supplementation for 24 Weeks on Physical Function, Body Composition, and Muscle Metabolism in Healthy, Independent Older Adults: A Randomized Clinical Trial

scientific article published on 01 September 2019

Effect of Blood Flow Restriction Training on Quadriceps Muscle Strength, Morphology, Physiology, and Knee Biomechanics Before and After Anterior Cruciate Ligament Reconstruction: Protocol for a Randomized Clinical Trial

scientific article published on 01 August 2019

Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women

scientific article

Essential amino acids increase microRNA-499, -208b, and -23a and downregulate myostatin and myocyte enhancer factor 2C mRNA expression in human skeletal muscle

scientific article published on 14 October 2009

Excess leucine intake enhances muscle anabolic signaling but not net protein anabolism in young men and women

scientific article

Exercise, amino acids, and aging in the control of human muscle protein synthesis.

scientific article published on December 2011

Fibre type-specific satellite cell response to aerobic training in sedentary adults

scientific article published on 31 March 2014

Fourteen days of bed rest induces a decline in satellite cell content and robust atrophy of skeletal muscle fibers in middle-aged adults

scientific article published on 21 January 2016

Fusion-Independent Satellite Cell Communication to Muscle Fibers During Load-Induced Hypertrophy

scientific article published on 06 July 2020

Glucocorticoids increase skeletal muscle NF-κB inducing kinase (NIK): links to muscle atrophy.

scientific article

Human skeletal muscle macrophages increase following cycle training and are associated with adaptations that may facilitate growth

scientific article published in Scientific Reports

Inducible depletion of satellite cells in adult, sedentary mice impairs muscle regenerative capacity without affecting sarcopenia

scientific article

Inducible satellite cell depletion attenuates skeletal muscle regrowth following a scald-burn injury

scientific article published on 22 August 2017

Insulin Stimulates Human Skeletal Muscle Protein Synthesis via an Indirect Mechanism Involving Endothelial-Dependent Vasodilation and Mammalian Target of Rapamycin Complex 1 Signaling.

scientific article

Insulin stimulates human skeletal muscle protein synthesis via an indirect mechanism involving endothelial-dependent vasodilation and mammalian target of rapamycin complex 1 signaling

scientific article

Insulin-resistant subjects have normal angiogenic response to aerobic exercise training in skeletal muscle, but not in adipose tissue

scientific article published in June 2015

Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults

scientific article published on 10 September 2019

Mammalian target of rapamycin complex 1 activation is required for the stimulation of human skeletal muscle protein synthesis by essential amino acids

scientific article

Measuring Exercise Capacity and Physical Function in Adult and Older Mice

scientific article published on 21 August 2020

Methodological issues limit interpretation of negative effects of satellite cell depletion on adult muscle hypertrophy.

scientific article

Moderate-intensity aerobic exercise improves skeletal muscle quality in older adults

scientific article published on 20 February 2019

Muscle Protein Anabolic Resistance to Essential Amino Acids Does Not Occur in Healthy Older Adults Before or After Resistance Exercise Training.

scientific article

Muscle protein breakdown has a minor role in the protein anabolic response to essential amino acid and carbohydrate intake following resistance exercise.

scientific article

MyoVision: software for automated high-content analysis of skeletal muscle immunohistochemistry

scientific article published on 5 October 2017

Myogenic Progenitor Cells Control Extracellular Matrix Production by Fibroblasts during Skeletal Muscle Hypertrophy

scientific article

Nutritional and contractile regulation of human skeletal muscle protein synthesis and mTORC1 signaling

scientific article

PAX7+ satellite cells in young and older adults following resistance exercise

scientific article

Paraplegia increases skeletal muscle autophagy

scientific article published on November 2012

Pharmacological vasodilation improves insulin-stimulated muscle protein anabolism but not glucose utilization in older adults ⬇️

scientific article

Post-absorptive muscle protein turnover affects resistance training hypertrophy.

scientific article

Postexercise essential amino acid supplementation amplifies skeletal muscle satellite cell proliferation in older men 24 hours postexercise

scientific article

Prior acetaminophen consumption impacts the early adaptive cellular response of human skeletal muscle to resistance exercise.

scientific article published on 11 January 2018

Protein Supplementation Does Not Affect Myogenic Adaptations to Resistance Training.

scientific article published on 14 February 2017

Protein blend ingestion following resistance exercise promotes human muscle protein synthesis

scientific article published on 23 January 2013

Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis

scientific article published on 2 February 2009

Rapamycin does not affect post-absorptive protein metabolism in human skeletal muscle

scientific article published on 06 September 2012

Reactive hyperemia is not responsible for stimulating muscle protein synthesis following blood flow restriction exercise

scientific article

Reduced voluntary running performance is associated with impaired coordination as a result of muscle satellite cell depletion in adult mice

scientific article

Regulation of the muscle fiber microenvironment by activated satellite cells during hypertrophy

scientific article published on 27 December 2013

Repetitive TLR-3 activation in the lung induces skeletal muscle adaptations and cachexia

scientific article published on 13 February 2018

Resistance exercise training promotes fiber type-specific myonuclear adaptations in older adults

scientific article published on 05 March 2020

Satellite cell activation and apoptosis in skeletal muscle from severely burned children.

scientific article published on 27 June 2016

Satellite cell depletion does not inhibit adult skeletal muscle regrowth following unloading-induced atrophy

scientific article

Skeletal Muscle Protein Balance and Metabolism in the Elderly ⬇️

scientific article published on December 1, 2011

Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise.

scientific article

Skeletal muscle autophagy and protein breakdown following resistance exercise are similar in younger and older adults

scientific article published on 22 October 2012

Skeletal muscle fibrosis is associated with decreased muscle inflammation and weakness in patients with chronic kidney disease

scientific article published on 03 October 2018

Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging

scientific article published on 06 March 2008

Skeletal muscle-specific knockout of DEP domain containing 5 protein increases mTORC1 signaling, muscle cell hypertrophy, and mitochondrial respiration

scientific article published on 11 January 2019

Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle

scientific article published on 10 February 2019

Starring or Supporting Role? Satellite Cells and Skeletal Muscle Fiber Size Regulation.

scientific article published in January 2018

Synergist Ablation as a Rodent Model to Study Satellite Cell Dynamics in Adult Skeletal Muscle

scientific article

The Importance of Resistance Exercise Training to Combat Neuromuscular Aging

scientific article published on 01 March 2019

The intersection of disuse-induced muscle atrophy and satellite cell content: reply to Snijders, Nederveen, and Parise.

scientific article published in June 2016

Thermal injury initiates pervasive fibrogenesis in skeletal muscle

scientific article published on 20 May 2020

Tiny transporters: how exosomes and calcineurin signaling regulate miR-23a levels during muscle atrophy. Focus on "miR-23a is decreased during muscle atrophy by a mechanism that includes calcineurin signaling and exosome-mediated export"

scientific article published on 22 January 2014

Whey Protein Hydrolysate Increases Amino Acid Uptake, mTORC1 Signaling, and Protein Synthesis in Skeletal Muscle of Healthy Young Men in a Randomized Crossover Trial

scientific article published on 01 July 2019

List of works by Christopher S Fry

2,000 Steps/Day Does Not Fully Protect Skeletal Muscle Health in Older Adults During Bed Rest

A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults.

ACL injury reduces satellite cell abundance and promotes fibrogenic cell expansion within skeletal muscle

Addition of carbohydrate or alanine to an essential amino acid mixture does not enhance human skeletal muscle protein anabolism

Aged Muscle Demonstrates Fiber-Type Adaptations in Response to Mechanical Overload, in the Absence of Myofiber Hypertrophy, Independent of Satellite Cell Abundance.

Aging differentially affects human skeletal muscle microRNA expression at rest and after an anabolic stimulus of resistance exercise and essential amino acids

Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis.

Aging-related effects of bed rest followed by eccentric exercise rehabilitation on skeletal muscle macrophages and insulin sensitivity

Altered satellite cell dynamics accompany skeletal muscle atrophy during chronic illness, disuse, and aging

An increase in essential amino acid availability upregulates amino acid transporter expression in human skeletal muscle

An obesogenic maternal environment impairs mouse growth patterns, satellite cell activation and markers of post-natal myogenesis

Anterior Cruciate Ligament Tear Promotes Skeletal Muscle Myostatin Expression, Fibrogenic Cell Expansion, and a Decline in Muscle Quality

Automated fiber-type-specific cross-sectional area assessment and myonuclei counting in skeletal muscle

Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults.

Blood flow restriction exercise stimulates mTORC1 signaling and muscle protein synthesis in older men

Chronic doxorubicin administration impacts satellite cell and capillary abundance in a muscle-specific manner

Chronic paraplegia-induced muscle atrophy downregulates the mTOR/S6K1 signaling pathway

Countering disuse atrophy in older adults with low volume leucine supplementation

Cycle training modulates satellite cell and transcriptional responses to a bout of resistance exercise

Effect of Aerobic Exercise Training and Essential Amino Acid Supplementation for 24 Weeks on Physical Function, Body Composition, and Muscle Metabolism in Healthy, Independent Older Adults: A Randomized Clinical Trial

Effect of Blood Flow Restriction Training on Quadriceps Muscle Strength, Morphology, Physiology, and Knee Biomechanics Before and After Anterior Cruciate Ligament Reconstruction: Protocol for a Randomized Clinical Trial

Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women

Essential amino acids increase microRNA-499, -208b, and -23a and downregulate myostatin and myocyte enhancer factor 2C mRNA expression in human skeletal muscle

Excess leucine intake enhances muscle anabolic signaling but not net protein anabolism in young men and women

Exercise, amino acids, and aging in the control of human muscle protein synthesis.

Fibre type-specific satellite cell response to aerobic training in sedentary adults

Fourteen days of bed rest induces a decline in satellite cell content and robust atrophy of skeletal muscle fibers in middle-aged adults

Fusion-Independent Satellite Cell Communication to Muscle Fibers During Load-Induced Hypertrophy

Glucocorticoids increase skeletal muscle NF-κB inducing kinase (NIK): links to muscle atrophy.

Human skeletal muscle macrophages increase following cycle training and are associated with adaptations that may facilitate growth

Inducible depletion of satellite cells in adult, sedentary mice impairs muscle regenerative capacity without affecting sarcopenia

Inducible satellite cell depletion attenuates skeletal muscle regrowth following a scald-burn injury

Insulin Stimulates Human Skeletal Muscle Protein Synthesis via an Indirect Mechanism Involving Endothelial-Dependent Vasodilation and Mammalian Target of Rapamycin Complex 1 Signaling.

Insulin stimulates human skeletal muscle protein synthesis via an indirect mechanism involving endothelial-dependent vasodilation and mammalian target of rapamycin complex 1 signaling

Insulin-resistant subjects have normal angiogenic response to aerobic exercise training in skeletal muscle, but not in adipose tissue

Low skeletal muscle capillarization limits muscle adaptation to resistance exercise training in older adults

Mammalian target of rapamycin complex 1 activation is required for the stimulation of human skeletal muscle protein synthesis by essential amino acids

Measuring Exercise Capacity and Physical Function in Adult and Older Mice

Methodological issues limit interpretation of negative effects of satellite cell depletion on adult muscle hypertrophy.

Moderate-intensity aerobic exercise improves skeletal muscle quality in older adults

Muscle Protein Anabolic Resistance to Essential Amino Acids Does Not Occur in Healthy Older Adults Before or After Resistance Exercise Training.

Muscle protein breakdown has a minor role in the protein anabolic response to essential amino acid and carbohydrate intake following resistance exercise.

MyoVision: software for automated high-content analysis of skeletal muscle immunohistochemistry

Myogenic Progenitor Cells Control Extracellular Matrix Production by Fibroblasts during Skeletal Muscle Hypertrophy

Nutritional and contractile regulation of human skeletal muscle protein synthesis and mTORC1 signaling

PAX7+ satellite cells in young and older adults following resistance exercise

Paraplegia increases skeletal muscle autophagy

Pharmacological vasodilation improves insulin-stimulated muscle protein anabolism but not glucose utilization in older adults ⬇️

Post-absorptive muscle protein turnover affects resistance training hypertrophy.

Postexercise essential amino acid supplementation amplifies skeletal muscle satellite cell proliferation in older men 24 hours postexercise

Prior acetaminophen consumption impacts the early adaptive cellular response of human skeletal muscle to resistance exercise.

Protein Supplementation Does Not Affect Myogenic Adaptations to Resistance Training.

Protein blend ingestion following resistance exercise promotes human muscle protein synthesis

Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis

Rapamycin does not affect post-absorptive protein metabolism in human skeletal muscle

Reactive hyperemia is not responsible for stimulating muscle protein synthesis following blood flow restriction exercise

Reduced voluntary running performance is associated with impaired coordination as a result of muscle satellite cell depletion in adult mice

Regulation of the muscle fiber microenvironment by activated satellite cells during hypertrophy

Repetitive TLR-3 activation in the lung induces skeletal muscle adaptations and cachexia

Resistance exercise training promotes fiber type-specific myonuclear adaptations in older adults

Satellite cell activation and apoptosis in skeletal muscle from severely burned children.

Satellite cell depletion does not inhibit adult skeletal muscle regrowth following unloading-induced atrophy

Skeletal Muscle Protein Balance and Metabolism in the Elderly ⬇️

Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise.

Skeletal muscle autophagy and protein breakdown following resistance exercise are similar in younger and older adults

Skeletal muscle fibrosis is associated with decreased muscle inflammation and weakness in patients with chronic kidney disease

Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging

Skeletal muscle-specific knockout of DEP domain containing 5 protein increases mTORC1 signaling, muscle cell hypertrophy, and mitochondrial respiration

Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle

Starring or Supporting Role? Satellite Cells and Skeletal Muscle Fiber Size Regulation.

Synergist Ablation as a Rodent Model to Study Satellite Cell Dynamics in Adult Skeletal Muscle

The Importance of Resistance Exercise Training to Combat Neuromuscular Aging

The intersection of disuse-induced muscle atrophy and satellite cell content: reply to Snijders, Nederveen, and Parise.

Thermal injury initiates pervasive fibrogenesis in skeletal muscle

Tiny transporters: how exosomes and calcineurin signaling regulate miR-23a levels during muscle atrophy. Focus on "miR-23a is decreased during muscle atrophy by a mechanism that includes calcineurin signaling and exosome-mediated export"

Whey Protein Hydrolysate Increases Amino Acid Uptake, mTORC1 Signaling, and Protein Synthesis in Skeletal Muscle of Healthy Young Men in a Randomized Crossover Trial