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List of works by Alzir A Batista

31P{1H}-n.m.r. as a tool for identification of ruthenium isomers containing PPh3 or 1,4-bis(diphenylphosphino)butane ligands. X-ray structures of the cis-{RuCl2(PPh3)2 [4,4?-(-X)2-2,2?-bipy]} complexes [X=-H, -Me, -SMe and (-Cl, -Me)]

4-Nitroacetophenone-derived thiosemicarbazones and their copper(II) complexes with significant in vitro anti-trypanosomal activity

scientific article published on 10 July 2007

A Novel Ruthenium(II) Complex With Lapachol Induces G2/M Phase Arrest Through Aurora-B Kinase Down-Regulation and ROS-Mediated Apoptosis in Human Prostate Adenocarcinoma Cells

scientific article published on 24 June 2021

A Ru(II)-p-cymene compound bearing naproxen-pyridineamide. Synthesis, spectroscopic studies, computational analysis and in vitro anticancer activity against lung cells compared to Ru(II)-p-cymene-naproxen and the corresponding drug ligands

scholarly article

A giant hybrid organic-inorganic octahedron from a narrow rim carboxylate calixarene

scientific article published on 13 November 2020

A new nitrosyl ruthenium complex: synthesis, chemical characterization, in vitro and in vivo antitumor activities and probable mechanism of action

scientific article published on 19 May 2011

A novel coordination mode for a pyridylphosphine ligand. X-ray structures of [RuCl 2 (NO)L] ( I ) and [RuCl 2 (NO)L]·DMSO ( II ) (L = [(2-py) 2 PC 2 H 4 POO(2-py) 2 ] - )

scholarly article by Alzir A. Batista et al published 2001 in Canadian Journal of Chemistry

A novel ruthenium(II) gallic acid complex disrupts the actin cytoskeleton and inhibits migration, invasion and adhesion of triple negative breast tumor cells

scientific article published on 11 December 2020

Analyzing Ru(III)–dmso and Ru(III)–dms motifs in compounds used in the synthesis of the antimetastatic agents

Anti-Mycobacterium tuberculosisand Cytotoxicity Activities of Ruthenium(II)/Bipyridine/Diphosphine/Pyrimidine-2-thiolate Complexes: The Role of the Non-CoordinatedN-Atom

article published in 2015

Antiparasitic activities of novel ruthenium/lapachol complexes.

scientific article published on 27 March 2014

Asymmetric heterobimetallic mixed-valence complex trans-[(SO3)Co(cyclam)(NCS)Ru(NH3)4(NCS)](BF4): Synthesis and characterization

Chiral Platinum(II) Complexes Featuring Phosphine and Chloroquine Ligands as Cytotoxic and Monofunctional DNA-Binding Agents.

scientific article published on 25 November 2015

Chloroquine-containing organoruthenium complexes are fast-acting multistage antimalarial agents

scientific article published on 21 July 2016

Cis-[RuCl(BzCN)(N-N)(P-P)]PF6 complexes: Synthesis and in vitro antitumor activity: (BzCN=benzonitrile; N-N=2,2'-bipyridine; 1,10-phenanthroline; P-P=1,4-bis(diphenylphosphino) butane, 1,2-bis(diphenylphosphino)ethane, or 1,1'-(diphenylphosphino)fer

scientific article published on 31 March 2015

Coordination of nitro-thiosemicarbazones to ruthenium(II) as a strategy for anti-trypanosomal activity improvement

scientific article published on 11 March 2010

Copper(II) complexes with (2-hydroxybenzyl-2-pyridylmethyl)amine–Hbpa: syntheses, characterization and crystal structures of the ligand and [Cu(II)(Hbpa)2](ClO4)2·2H2O ⬇️

scholarly article

Crystal structure and catalytic activity of ruthenium (II)/dithiocarbamate complexes in the epoxidation of cyclooctene

Crystal structure, electrochemical and photochemical studies of the trans-[Fe(cyclam)(NO)Cl]Cl2 complex (cyclam=1,4,8,11-tetraazacyclotetradecane)

Crystal structure, electrochemical and spectroscopic properties of the trans-K{[FeCl(NO0)(cyclam)]·[FeCl(NO+)(cyclam)]2}(PF6)6 complex

Cytotoxic activity and structural features of Ru(II)/phosphine/amino acid complexes

scientific article published on 23 December 2017

Cytotoxicity and anti-tumor effects of new ruthenium complexes on triple negative breast cancer cells

scientific article published on 12 September 2017

Cytotoxicity of Ru(II) piano-stool complexes with chloroquine and chelating ligands against breast and lung tumor cells: Interactions with DNA and BSA.

scientific article published on 23 July 2015

Cytotoxicity of ruthenium-N,N-disubstituted-N'-acylthioureas complexes

scientific article published on 20 May 2020

Dependence of the product on the P–P ligand in reactions of [RuCl3(NO)(P–P)] complexes (P–P=aromatic diphosphines) with 2-mercaptopyridine

Determination of in vitro absorption in Caco-2 monolayers of anticancer Ru(II)-based complexes acting as dual human topoisomerase and PARP inhibitors

scientific article published on 30 November 2018

Dichloro(diphosphine)(2-pyridyl-ketone)ruthenium(II) complexes

Driving forces in substitution reactions of octahedral complexes: The influence of the competitive effect

Esterification of the free carboxylic group from the lutidinic acid ligand as a tool to improve the cytotoxicity of Ru(ii) complexes

Evaluation of the biological potential of ruthenium(II) complexes with cinnamic acid

scientific article published on 14 February 2020

Experimental and theoretical investigation of molecular structure and conformation of the 4-isopropylthioxanthone

Experimental and theoretical studies of copper complexes with isomeric dipeptides as novel candidates against breast cancer

scientific article published on 4 June 2016

Experimental and theoretical study of the kinetics of dissociation in cis-[RuCl2(P-P)(N-N)] type complexes

Half sandwich Ru(ii)-acylthiourea complexes: DNA/HSA-binding, anti-migration and cell death in a human breast tumor cell line.

scientific article published on 18 September 2017

Heterobimetallic Ru(ii)/Fe(ii) complexes as potent anticancer agents against breast cancer cells, inducing apoptosis through multiple targets

scientific article published on 28 February 2020

Heterobimetallic [Ru(II)/Fe(II)] complexes: On the formation of trans- and cis-[RuCl2(dppf)(diimines)]

Heterobimetallic compounds [Ru(η5-Cp)(dppf)X] (X = Cl, Br, I and N3): synthesis, electrochemical analysis, and the crystal structure of [Ru(η5-Cp)(dppf)I] [dppf = 1,1′-bis(diphenylphosphino)ferrocene]

Heteroleptic tris-chelate ruthenium(II) complexes of N , N -disubstituted- N ′-acylthioureas: Synthesis, structural studies, cytotoxic activity and confocal microscopy studies

scientific article published in April 2017

Human topoisomerase inhibition and DNA/BSA binding of Ru(II)-SCAR complexes as potential anticancer candidates for oral application.

scientific article

Hydrolysis reaction promotes changes in coordination mode of Ru(II)/acylthiourea organometallic complexes with cytotoxicity against human lung tumor cell lines

scientific article published on 18 June 2018

Hydroxyl Radical Generation and DNA Nuclease Activity: A Mechanistic Study Based on a Surface-Immobilized Copper Thioether Clip-Phen Derivative

scientific article published on 16 June 2016

In vitro and in vivo activities of ruthenium(II) phosphine/diimine/picolinate complexes (SCAR) against Mycobacterium tuberculosis

scientific article

In vitro and in vivo antitumor activity of a novel carbonyl ruthenium compound, the ct-[RuCl(CO)(dppb)(bipy)]PF-6[dppb=1,4-bis(diphenylphosphine)butane and bipy=2,2'-bipyridine].

scientific article published on 25 August 2016

In vitro cytotoxicity and in vivo zebrafish toxicity evaluation of Ru(ii)/2-mercaptopyrimidine complexes

scientific article published on 01 May 2019

Influence of gold nanoparticles applied to catalytic hydrogenation of acetophenone with cationic complexes containing ruthenium

scholarly article in RSC Advances, vol. 6 no. 58, 2016

Inhibition of human DNA topoisomerase IB by nonmutagenic ruthenium(II)-based compounds with antitumoral activity.

scientific article published on 13 January 2016

Lapachol in the Design of a New Ruthenium(II)-Diphosphine Complex as a Promising Anticancer Metallodrug

scientific article published on 23 October 2020

Magnetic-field-tuned phase transition of a molecular material from the isolated-spin to the coupled-spin regime

scientific article published on 01 February 2019

Manganese(II) complexes with thiosemicarbazones as potential anti-Mycobacterium tuberculosis agents

scientific article published on 25 October 2013

Modified glassy carbon electrode with AuNPs using cis-[RuCl(dppb)(bipy)(4-vpy)]+ as crossed linking agent

Mono- and dinuclear copper(I) complexes with methyl-substituted pyrimidinethiones

NH⋯Br, Br⋯π and π⋯π interactions toward self-assembly of the cytosine hydrobromide: Crystal structure, infrared spectroscopy and thermal behavior

scholarly article by Juan C. Tenorio et al published September 2013 in Journal of Molecular Structure

New Ni(II)-sulfonamide complexes: synthesis, structural characterization and antibacterial properties. X-ray diffraction of [Ni(sulfisoxazole)2(H2O)4].2H2O and [Ni(sulfapyridine)2].

scientific article published on 26 September 2007

New ruthenium(II)/phosphines/diimines complexes: Promising antitumor (human breast cancer) and Mycobacterium tuberculosis fighting agents

scholarly article by Edjane R. dos Santos et al published March 2013 in Polyhedron

Nitro/nitrosyl-ruthenium complexes are potent and selective anti-Trypanosoma cruzi agents causing autophagy and necrotic parasite death

scientific article

Non-mutagenic Ru(ii) complexes: cytotoxicity, topoisomerase IB inhibition, DNA and HSA binding

scientific article published on 01 October 2019

Novel manganese (III) porphyrin containing peripheral “[RuCl(dppb)(X-bipy)]+” cations [dppb=1,4-bis(diphenylphosphino)butane and X=–CH3, –OMe, –Cl]. X-ray structure of the cis-[RuCl(dppb)(bipy)(4-Mepy)]PF6 complex

Novel piplartine-containing ruthenium complexes: synthesis, cell growth inhibition, apoptosis induction and ROS production on HCT116 cells.

scientific article published in November 2017

Nucleobase Derivatives as Building Blocks to Form Ru(II)-Based Complexes with High Cytotoxicity

scientific article published on 03 January 2020

On a ruthenium nitrosyl and monocoordinated biphosphine monoxide complex: Synthesis, characterization and X-ray structure of

On an electrode modified by a supramolecular ruthenium mixed valence (Ru(II)/Ru(III)) diphosphine-porphyrin assembly

scientific article published in June 2009

On the Cytotoxicity of Chiral Ruthenium Complexes Containing Sulfur Amino Acids Against Breast Tumor Cells (MDA-231 and MCF-7)

scientific article published on 24 August 2020

On the cytotoxic activity of Pd(II) complexes of N,N-disubstituted-N'-acyl thioureas.

scientific article published on 8 February 2014

On the synthesis and structures of the complexes [RuCl(L)(dppb)(N–N)]PF6 (L=CO, py or 4-NH2py; dppb=1,4-bis(diphenylphosphino)butane; N–N=2,2′-bipyridine or 1,10-phenanthroline) and [(dppb)(CO)Cl2-Ru-pz-RuCl2(CO)(dppb)] (pz=pyrazine)

article published in 2010

Palladium(II) complexes of 2-benzoylpyridine-derived thiosemicarbazones: spectral characterization, structural studies and cytotoxic activity.

scientific article published on 24 December 2004

Palladium(II) complexes with thiosemicarbazones: syntheses, characterization and cytotoxicity against breast cancer cells and Anti-Mycobacterium tuberculosis activity

scholarly article by Pedro I. da S. Maia et al published 2010 in Journal of the Brazilian Chemical Society

Palladium(II)/ N , N -disubstituted- N ′-acylthioureas complexes as anti- Mycobacterium tuberculosis and anti- Trypanosoma cruzi agents

scholarly article by Ana M. Plutín et al published August 2017 in Polyhedron

Palladium(ii) complexes with thiosemicarbazones derived from pyrene as topoisomerase IB inhibitors

scientific article published on 01 November 2019

Platinum(ii)-chloroquine complexes are antimalarial agents against blood and liver stages by impairing mitochondrial function

scientific article published on 29 September 2017

Polypyridyl Ruthenium Complexes: Novel DNA-Intercalating Agents against Human Breast Tumor

Preparation, characterization and structure of ruthenium phosphine complexes containing non-innocent ligands

Propyl gallate metal complexes: Circular dichroism, BSA-binding, antioxidant and cytotoxic activity

Remarkable Electronic Effect on the meso-Tetra(thienyl)porphyrins

scientific article published on 03 January 2019

Rhenium chelate complexes with maltolate or kojate

scholarly article by André Gustavo de A. Fernandes et al published September 2008 in Polyhedron

Ru(II) complexes containing uracil nucleobase analogs with cytotoxicity against tumor cells

scientific article published on 09 June 2019

Ru(II)-Based Amino Acid Complexes Show Promise for Leukemia Treatment: Cytotoxicity and Some Light on their Mechanism of Action

scientific article published on 26 November 2019

Ru(II)-based complexes with N-(acyl)-N',N'-(disubstituted)thiourea ligands: Synthesis, characterization, BSA- and DNA-binding studies of new cytotoxic agents against lung and prostate tumour cells.

scientific article published on 22 April 2015

Ru(II)-thymine complex causes DNA damage and apoptotic cell death in human colon carcinoma HCT116 cells mediated by JNK/p38/ERK1/2 via a p53-independent signaling

scientific article published on 31 July 2019

Ru(II)/N-N/PPh3 complexes as potential anticancer agents against MDA-MB-231 cancer cells (N-N = diimine or diamine)

scientific article published on 18 January 2019

Ru(II)/bisphosphine/diimine/amino acid complexes: diastereoisomerism, cytotoxicity, and inhibition of tumor cell adhesion to collagen type I

Ru(II)/clotrimazole/diphenylphosphine/bipyridine complexes: Interaction with DNA, BSA and biological potential against tumor cell lines and Mycobacterium tuberculosis

scientific article published on 25 June 2016

Ru(II)/diclofenac-based complexes: DNA, BSA interaction and their anticancer evaluation against lung and breast tumor cells

scientific article published on 01 September 2020

Ru(II)/diphenylphosphine/pyridine-6-thiolate complexes induce S-180 cell apoptosis through intrinsic mitochondrial pathway involving inhibition of Bcl-2 and p53/Bax activation.

scientific article published on 9 August 2017

Ru(ii)-Naphthoquinone complexes with high selectivity for triple-negative breast cancer

scientific article published on 24 April 2020

Ru(ii)–thyminate complexes: new metallodrug candidates against tumor cells

Ruthenium (II) phosphine/picolinate complexes as antimycobacterial agents

scientific article published on 6 November 2009

Ruthenium Complexes Containing Heterocyclic Thioamidates Trigger Caspase-Mediated Apoptosis Through MAPK Signaling in Human Hepatocellular Carcinoma Cells

scientific article published on 09 July 2019

Ruthenium Complexes With Piplartine Cause Apoptosis Through MAPK Signaling by a p53-Dependent Pathway in Human Colon Carcinoma Cells and Inhibit Tumor Development in a Xenograft Model

scientific article published on 03 July 2019

Ruthenium Phosphine/Diimine Complexes: Syntheses, Characterization, Reactivity with Carbon Monoxide, and Catalytic Hydrogenation of Ketones†

Ruthenium complexes containing the hemilabile ligand PPh2(CH2)P(O)PPh2 (dppmO): reactivity towards CO and X-ray molecular structures of tcc-RuCl2(η2-dppmO)2 and mer-RuCl3(η1,η2-dppmO)2

Ruthenium(II) Phosphine/Mercapto Complexes: Their in Vitro Cytotoxicity Evaluation and Actions as Inhibitors of Topoisomerase and Proteasome Acting as Possible Triggers of Cell Death Induction

scientific article published on 30 September 2020

Ruthenium(II) complexes containing 2-pyridineformamide- and 2-benzoylpyridine-derived thiosemicarbazones and PPh3: NMR and electrochemical studies of cis-trans-isomerization

scientific article published on 17 July 2007

Ruthenium(II) complexes containing N(4)-tolyl-2-acetylpyridine thiosemicarbazones and phosphine ligands: NMR and electrochemical studies of cis–trans isomerization

Ruthenium(II) complexes of 1,3-thiazolidine-2-thione: Cytotoxicity against tumor cells and anti-Trypanosoma cruzi activity enhanced upon combination with benznidazole

scientific article published on 02 January 2016

Ruthenium(II) complexes of 2-benzoylpyridine-derived thiosemicarbazones with cytotoxic activity against human tumor cell lines

scientific article published on 9 June 2007

Ruthenium(II) complexes with 6-methyl-2-thiouracil selectively reduce cell proliferation, cause DNA double-strand break and trigger caspase-mediated apoptosis through JNK/p38 pathways in human acute promyelocytic leukemia cells

scientific article published on 07 August 2019

Ruthenium(II) complexes with hydroxypyridinecarboxylates: Screening potential metallodrugs against Mycobacterium tuberculosis

scholarly article by Marília I.F. Barbosa et al published January 2015 in Polyhedron

Ruthenium(II) phosphine/diimine/picolinate complexes: inorganic compounds as agents against tuberculosis

scientific article

Ruthenium(II)/4,6-dimethyl-2-mercaptopyrimidine complexes: Synthesis, characterization, X-ray structures and in vitro cytotoxicity activities on cancer cell lines

Ruthenium(II)/Benzonitrile Complex Induces Cytotoxic Effect in Sarcoma-180 Cells by Caspase-Mediated and Tp53/p21-Mediated Apoptosis, with Moderate Brine Shrimp Toxicity

scientific article published on 08 April 2020

Ruthenium(II)/triphenylphosphine complexes: An effective way to improve the cytotoxicity of lapachol

Selective Coordination Mode of Acylthiourea Ligands in Half-Sandwich Ru(II) Complexes and Their Cytotoxic Evaluation

scientific article published on 25 March 2020

Selective Ru(II)/lawsone complexes inhibiting tumor cell growth by apoptosis.

scientific article

Spectroscopic Investigation on the Formation of a Dinuclear Me2SO–Ru2-Mercaptopyridine Bridged Complex: [Ru2Cl3(μ-pyS)(μ-dmso)(dmso)4] · 2H2O

Structural features and cytotoxic activities of [Ru(AA-H)(dppb)(bipy)]PF6 complexes

Study of the cytotoxic and genotoxic potential of the carbonyl ruthenium(II) compound, ct-[RuCl(CO)(dppb)(bipy)]PF6 [dppb = 1,4-bis(diphenylphosphino)butane and bipy = 2,2'-bipyridine], by in vitro and in vivo assays

scientific article published on 20 November 2018

Syntheses, characterization and X-ray structures of the fac-[RuCl3(NO)(dppe)] and the trans-[RuCl(NO)(dppe)2]2+ species

article

Synthesis and characterization of [Ru(η6-C10H14)(dppf)X][PF6] (X=Cl, Br, I, SnF3) compounds: The X-ray structure of [Ru(η6-C10H14)(dppf)Cl][SnCl3]·0.45CH2Cl2

article published in 2012

Synthesis and structural characterization of a series of ternary copper(II)-L-dipeptide-neocuproine complexes. Study of their cytotoxicity against cancer cells including MDA-MB-231, triple negative breast cancer cells

scientific article published on 18 November 2019

Synthesis, Characterization, Cytotoxic Activity, and Interactions with CT-DNA and BSA of Cationic Ruthenium(II) Complexes Containing Dppm and Quinoline Carboxylates

scientific article

Synthesis, Structural, Spectroscopic and Electrochemical Characterization of New Ruthenium(II) Tetramer Complexes Containing 1,4-Bis(diphenylphosphine)butane and Alterdentate Ligands

Synthesis, characterization and cytotoxic activities of the [RuCl2(NO)(dppp)(L)]PF6 complexes

scientific article

Synthesis, characterization and reactivity of halides/pseudohalides and their complexes containing ruthenium II in the hydrogenation of cyclohexene

Synthesis, characterization and structure of ruthenium(II) phosphine complexes with N-heterocyclic thiolate ligands

Synthesis, characterization, X-ray structure and in vitro antimycobacterial and antitumoral activities of Ru(II) phosphine/diimine complexes containing the "SpymMe2" ligand, SpymMe2=4,6-dimethyl-2-mercaptopyrimidine

scientific article

Synthesis, characterization, and structure of a new N-nitrosamine of cyclam (1,4,8,11-tetraazacyclotetradecane)

The RuCl3(dppb)H2O complex: A new metal-assisted oxidative dehydrogenation of the o-phenylenediamine ligand

article published in 2005

The effect of guest molecules on the conformation and molecular assembly of the fac-[RuCl3(NO)(dppb)] complex

scholarly article by Rodrigo S. Corrêa et al published September 2013 in Journal of Molecular Structure

The first P–N containing RuCl3NO complex: fac-[RuCl3(NO)(P–N)] (P–N=[o-(N,N-dimethylamino)phenyl]diphenylphosphine)

The mer-[RuCl3(dppb)(H2O)] complex: A versatile tool for synthesis of RuII compounds

The versatility of the 1,4-dithiane ligand towards the coordination chemistry of ruthenium-phosphine complexes

Thiosemicarbazones, semicarbazones, dithiocarbazates and hydrazide/hydrazones: anti-Mycobacterium tuberculosis activity and cytotoxicity

scientific article

Transport of the Ruthenium Complex [Ru(GA)(dppe)2]PF6 into Triple-Negative Breast Cancer Cells Is Facilitated by Transferrin Receptors

scientific article published on 25 January 2019

Understanding the conformational changes and molecular structure of furoyl thioureas upon substitution

scientific article published on 28 December 2016

Vanadium complexes with thiosemicarbazones: Synthesis, characterization, crystal structures and anti-Mycobacterium tuberculosis activity

scholarly article by Pedro I. da S. Maia et al published February 2009 in Polyhedron

Weak C—H...Cl—Pd interactions toward conformational polymorphism intrans-dichloridobis(triphenylphosphane)palladium(II)

scientific article published on 26 August 2011

cis-[RuCl(BzCN)(bipy)(dppe)]PF6 induces anti-angiogenesis and apoptosis by a mechanism of caspase-dependent involving DNA damage, PARP activation, and Tp53 induction in Ehrlich tumor cells.

scientific article

mer-[RuCl3(P–P)H2O] (P–P=dppb or diop) as a starting material for the synthesis of binuclear complexes. Crystallographic structures of [(dppb)ClRu–μ(Cl)3–RuCl(dppb)] and [(η6-C6H6)Ru–μ(Cl)3–RuCl(dppb)]

meso -Tetra-(4-pyridyl)porphyrin/palladium( ii ) complexes as anticancer agents

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