List of works - Ricardo Tapia

AMPA receptor activation, but not the accumulation of endogenous extracellular glutamate, induces paralysis and motor neuron death in rat spinal cord in vivo.

scientific article

Activation of group III metabotropic glutamate receptors by endogenous glutamate protects against glutamate-mediated excitotoxicity in the hippocampus in vivo

scientific article published on 18 January 2012

Ca2+-permeable AMPA receptors and intracellular Ca2+ determine motoneuron vulnerability in rat spinal cord in vivo

scientific article published on 20 January 2007

Calpain inhibition protects spinal motoneurons from the excitotoxic effects of AMPA in vivo.

scientific article published on 25 January 2008

Cerebral neurons of transgenic ALS mice are vulnerable to glutamate release stimulation but not to increased extracellular glutamate due to transport blockade.

scientific article published on 20 December 2005

Chronic GABAergic blockade in the spinal cord in vivo induces motor alterations and neurodegeneration

scientific article published in February 2017

Chronic elevation of extracellular glutamate due to transport blockade is innocuous for spinal motoneurons in vivo

scientific article

Chronic infusion of SOD1G93A astrocyte-secreted factors induces spinal motoneuron degeneration and neuromuscular dysfunction in healthy rats.

scientific article

Degeneration of spinal motor neurons by chronic AMPA-induced excitotoxicity in vivo and protection by energy substrates.

scientific article published on 14 May 2015

Delayed administration of VEGF rescues spinal motor neurons from death with a short effective time frame in excitotoxic experimental models in vivo.

scientific article published on 27 March 2012

Energy substrates protect hippocampus against endogenous glutamate-mediated neurodegeneration in awake rats.

scientific article published in May 2014

Experimental models for the study of neurodegeneration in amyotrophic lateral sclerosis

scientific article

Expression of heat shock protein 70 induced by 4-aminopyridine through glutamate-mediated excitotoxic stress in rat hippocampus in vivo

scientific article published in October 2003

Glutamate excitotoxicity and therapeutic targets for amyotrophic lateral sclerosis.

scientific article

HSP70 expression protects against hippocampal neurodegeneration induced by endogenous glutamate in vivo

scientific article

High extracellular gamma-aminobutyric acid protects cultured neurons against damage induced by the accumulation of endogenous extracellular glutamate.

scientific article

Histone deacetylases and their role in motor neuron degeneration

scientific article

Influence of serum-free medium on the expression of glutamate transporters and the susceptibility to glutamate toxicity in cultured cortical neurons.

scientific article published in March 2003

Late N-methyl-D-aspartate receptor blockade rescues hippocampal neurons from excitotoxic stress and death after 4-aminopyridine-induced epilepsy.

scientific article

Mitochondrial Dysfunction during the Early Stages of Excitotoxic Spinal Motor Neuron Degeneration in Vivo

scientific article published on 18 April 2016

Neuropathological characterization of spinal motor neuron degeneration processes induced by acute and chronic excitotoxic stimulus in vivo.

scientific article published on 16 June 2016

Quercetin prevents spinal motor neuron degeneration induced by chronic excitotoxic stimulus by a sirtuin 1-dependent mechanism

scientific article published on 21 November 2017

Role of energy metabolic deficits and oxidative stress in excitotoxic spinal motor neuron degeneration in vivo

scientific article

Spinal inhibitory circuits and their role in motor neuron degeneration

scientific article published on 21 October 2013

Tetanus toxin C-fragment protects against excitotoxic spinal motoneuron degeneration in vivo

scientific article published in Scientific Reports

Trophic factors as modulators of motor neuron physiology and survival: implications for ALS therapy

scientific article

VEGF protects spinal motor neurons against chronic excitotoxic degeneration in vivo by activation of PI3-K pathway and inhibition of p38MAPK.

scientific article published in December 2010

Vascular endothelial growth factor prevents paralysis and motoneuron death in a rat model of excitotoxic spinal cord neurodegeneration

scientific article published in October 2007

List of works by Ricardo Tapia

AMPA receptor activation, but not the accumulation of endogenous extracellular glutamate, induces paralysis and motor neuron death in rat spinal cord in vivo.

Activation of group III metabotropic glutamate receptors by endogenous glutamate protects against glutamate-mediated excitotoxicity in the hippocampus in vivo

Ca2+-permeable AMPA receptors and intracellular Ca2+ determine motoneuron vulnerability in rat spinal cord in vivo

Calpain inhibition protects spinal motoneurons from the excitotoxic effects of AMPA in vivo.

Cerebral neurons of transgenic ALS mice are vulnerable to glutamate release stimulation but not to increased extracellular glutamate due to transport blockade.

Chronic GABAergic blockade in the spinal cord in vivo induces motor alterations and neurodegeneration

Chronic elevation of extracellular glutamate due to transport blockade is innocuous for spinal motoneurons in vivo

Chronic infusion of SOD1G93A astrocyte-secreted factors induces spinal motoneuron degeneration and neuromuscular dysfunction in healthy rats.

Degeneration of spinal motor neurons by chronic AMPA-induced excitotoxicity in vivo and protection by energy substrates.

Delayed administration of VEGF rescues spinal motor neurons from death with a short effective time frame in excitotoxic experimental models in vivo.

Energy substrates protect hippocampus against endogenous glutamate-mediated neurodegeneration in awake rats.

Experimental models for the study of neurodegeneration in amyotrophic lateral sclerosis

Expression of heat shock protein 70 induced by 4-aminopyridine through glutamate-mediated excitotoxic stress in rat hippocampus in vivo

Glutamate excitotoxicity and therapeutic targets for amyotrophic lateral sclerosis.

HSP70 expression protects against hippocampal neurodegeneration induced by endogenous glutamate in vivo

High extracellular gamma-aminobutyric acid protects cultured neurons against damage induced by the accumulation of endogenous extracellular glutamate.

Histone deacetylases and their role in motor neuron degeneration

Influence of serum-free medium on the expression of glutamate transporters and the susceptibility to glutamate toxicity in cultured cortical neurons.

Late N-methyl-D-aspartate receptor blockade rescues hippocampal neurons from excitotoxic stress and death after 4-aminopyridine-induced epilepsy.

Mitochondrial Dysfunction during the Early Stages of Excitotoxic Spinal Motor Neuron Degeneration in Vivo

Neuropathological characterization of spinal motor neuron degeneration processes induced by acute and chronic excitotoxic stimulus in vivo.

Quercetin prevents spinal motor neuron degeneration induced by chronic excitotoxic stimulus by a sirtuin 1-dependent mechanism

Role of energy metabolic deficits and oxidative stress in excitotoxic spinal motor neuron degeneration in vivo

Spinal inhibitory circuits and their role in motor neuron degeneration

Tetanus toxin C-fragment protects against excitotoxic spinal motoneuron degeneration in vivo

Trophic factors as modulators of motor neuron physiology and survival: implications for ALS therapy

VEGF protects spinal motor neurons against chronic excitotoxic degeneration in vivo by activation of PI3-K pathway and inhibition of p38MAPK.

Vascular endothelial growth factor prevents paralysis and motoneuron death in a rat model of excitotoxic spinal cord neurodegeneration