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List of works by Marcel A.T.M. van Vugt

14-3-3sigma controls mitotic translation to facilitate cytokinesis

scientific article published on March 2007

A haploid genetic screen identifies the G1/S regulatory machinery as a determinant of Wee1 inhibitor sensitivity.

scientific article

A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint

scientific article

APC/C(Cdh1) controls CtIP stability during the cell cycle and in response to DNA damage.

scientific article

Breaking the DNA damage response to improve cervical cancer treatment.

scientific article

CLIP-170 facilitates the formation of kinetochore-microtubule attachments

scientific article

CXCR4 and CXCL12 Expression in Rectal Tumors of Stage IV Patients Before and After Local Radiotherapy and Systemic Neoadjuvant Treatment

scientific article published on January 2015

Cell cycle re-entry mechanisms after DNA damage checkpoints: giving it some gas to shut off the breaks!

scientific article published on June 2010

Checkpoint adaptation and recovery: back with Polo after the break

scientific article

Claspin: timing the cell cycle arrest when the genome is damaged

scientific article published on 15 December 2006

Controlling the response to DNA damage by the APC/C-Cdh1.

scientific article

Cyclin E expression is associated with high levels of replication stress in triple-negative breast cancer

scientific article published on 07 September 2020

DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization ⬇️

scientific article published on October 8, 2010

Editorial: Cancer-Associated Defects in the DNA Damage Response: Drivers for Malignant Transformation and Potential Therapeutic Targets

scientific article published on 22 December 2015

Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability

scientific article published on 09 June 2021

Erratum to: Controlling the response to DNA damage by the APC/C-Cdh1.

scientific article published on June 2016

Functional dynamics of Polo-like kinase 1 at the centrosome.

scientific article published on 23 March 2009

Functional validation of putative tumor suppressor gene C13ORF18 in cervical cancer by Artificial Transcription Factors ⬇️

scientific article published on March 5, 2013

Gene expression analysis identifies global gene dosage sensitivity in cancer.

scientific article published on 12 January 2015

Getting in and out of mitosis with Polo-like kinase-1.

scientific article

Harnessing Integrative Omics to Facilitate Molecular Imaging of the Human Epidermal Growth Factor Receptor Family for Precision Medicine.

scientific article

Improving gene function predictions using independent transcriptional components

scientific article published on 05 March 2021

Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling

scientific article published on 15 June 2010

MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling

scientific article published in 2022

Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

scientific article published on 01 August 2019

Molecular imaging for monitoring treatment response in breast cancer patients.

scientific article published on 30 March 2013

Nuclear COMMD1 Is Associated with Cisplatin Sensitivity in Ovarian Cancer

scientific article

Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to replication checkpoint inhibitors

scientific article published on 07 October 2020

PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy

scientific article published on 19 January 2017

Perspectives for tailored chemoprevention and treatment of colorectal cancer in Lynch syndrome.

scientific article published on 14 December 2010

Plk1 Manages DNA break repair during mitosis

scientific article published in January 2015

Polo-like kinase-1 controls Aurora A destruction by activating APC/C-Cdh1

scientific article published in 2009

Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells

scientific article published on September 2004

Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/Cdc20 activation and initiation of cytokinesis

scientific article published on 21 June 2004

Polo-like kinase-1: activity measurement and RNAi-mediated knockdown

scientific article

Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition-mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2-deficient cancer cells

scientific article published on 21 October 2019

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells

scientific article

Quantitative proteomics analysis identifies MUC1 as an effect sensor of EGFR inhibition

scientific article published on 10 October 2018

Regulators of homologous recombination repair as novel targets for cancer treatment.

scientific article

Restarting the cell cycle when the checkpoint comes to a halt

scientific article

Rif1 Is Required for Resolution of Ultrafine DNA Bridges in Anaphase to Ensure Genomic Stability.

scientific article published on 5 August 2015

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality

scientific article published on 01 June 2018

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.

scientific article published in June 2019

Shutting down the power supply for DNA repair in cancer cells.

scientific article published on 25 January 2017

Studying platinum sensitivity and resistance in high-grade serous ovarian cancer: Different models for different questions

scientific article published on 26 November 2015

Systematic Discovery of In Vivo Phosphorylation Networks

scientific article (publication date: June 2007)

The DNA damage response during mitosis.

scientific article published on 21 July 2013

The RECQL helicase prevents replication fork collapse during replication stress

scientific article published on 20 August 2020

The role of ATM and 53BP1 as predictive markers in cervical cancer.

scientific article

Therapeutic targeting and patient selection for cancers with homologous recombination defects.

scientific article

Uncoupling anaphase-promoting complex/cyclosome activity from spindle assembly checkpoint control by deregulating polo-like kinase 1.

scientific article

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