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List of works by Leonard H Wexler

20-year experience with intraoperative high-dose-rate brachytherapy for pediatric sarcoma: outcomes, toxicity, and practice recommendations

scientific article published on 01 October 2014

A Molecular Study of Pediatric Spindle and Sclerosing Rhabdomyosarcoma: Identification of Novel and Recurrent VGLL2-related Fusions in Infantile Cases

scientific article

A clinicopathologic study of head and neck rhabdomyosarcomas showing FOXO1 fusion-positive alveolar and MYOD1-mutant sclerosing are associated with unfavorable outcome

scientific article

A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors

scientific article

A phase II trial of thalidomide and cyclophosphamide in patients with recurrent or refractory pediatric malignancies

scientific article published in September 2007

A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations

scientific article

A single-center experience with undifferentiated embryonal sarcoma of the liver

scientific article

Abstract PR012: Targeted sequencing of 2,138 bone and soft tissue sarcomas reveals commonly altered pathways, subtype-independent genetic clusters, and potential therapeutic targets

scientific article published in 2022

Addition of pamidronate to chemotherapy for the treatment of osteosarcoma

scientific article

Adjuvant chemotherapy for the treatment of advanced pediatric nonrhabdomyosarcoma soft tissue sarcoma: the National Cancer Institute experience

scientific article published in May 2005

Adult rhabdomyosarcoma survival improved with treatment on multimodality protocols.

scientific article published on 13 February 2013

Analysis of serum insulin growth factor-1 concentrations in localized osteosarcoma: a children's oncology group study

scientific article published on 31 October 2013

Assessment and Treatment Outcomes of Persistent Radiation-Induced Alopecia in Patients With Cancer

scientific article published on 05 August 2020

BCOR-CCNB3 Fusion Positive Sarcomas: A Clinicopathologic and Molecular Analysis of 36 Cases With Comparison to Morphologic Spectrum and Clinical Behavior of Other Round Cell Sarcomas

scientific article published on 25 October 2017

Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary.

scientific article published on November 2003

Central nervous system relapse of rhabdomyosarcoma

scientific article

Clinical and molecular heterogeneity of head and neck spindle cell and sclerosing rhabdomyosarcoma

scientific article

Clinical presentation, treatment, and outcome of alveolar soft part sarcoma in children, adolescents, and young adults.

scientific article

Computed tomographic scan of the chest underestimates the number of metastatic lesions in osteosarcoma.

scientific article

Concurrent radiation with irinotecan and carboplatin in intermediate‐ and high‐risk rhabdomyosarcoma: A report on toxicity and efficacy from a prospective pilot phase II study ⬇️

scientific article published on May 22, 2012

Effects of dexrazoxane on doxorubicin-related cardiotoxicity and second malignant neoplasms in children with osteosarcoma: a report from the Children's Oncology Group

scientific article published on 28 October 2019

Effects of therapy on dentofacial development in long-term survivors of head and neck rhabdomyosarcoma: the memorial sloan-kettering cancer center experience

scientific article

Ewing sarcomas with p53 mutation or p16/p14ARF homozygous deletion: a highly lethal subset associated with poor chemoresponse

scientific article published in January 2005

Exenteration and Custom Implant Brachytherapy as a Treatment for Recurrent Primary Extraskeletal Orbital Ewing Sarcoma

scientific article published on July 2015

Expanding the Spectrum of Intraosseous Rhabdomyosarcoma: Correlation Between 2 Distinct Gene Fusions and Phenotype

scientific article published on 01 May 2019

Extracellular vesicle and particle biomarkers define multiple human cancers

journal article published in 2020

Favorable outcomes after whole abdominopelvic radiation therapy for pediatric and young adult sarcoma

scientific article published on 04 May 2014

Frequent HRAS Mutations in Malignant Ectomesenchymoma: Overlapping Genetic Abnormalities With Embryonal Rhabdomyosarcoma

scientific article published on 11 February 2016

Gastrointestinal stromal tumors in children and young adults: a clinicopathologic, molecular, and genomic study of 15 cases and review of the literature

scientific article

Genomic Determinants of Clinical Outcomes in Rhabdomyosarcoma

scientific article published on 07 November 2019

Ifosfamide dose-intensification for patients with metastatic Ewing sarcoma

scientific article published on 28 January 2015

Immunogenic neoantigens derived from gene fusions stimulate T cell responses

scientific article published on 22 April 2019

Immunotherapeutic Targeting of GPC3 in Pediatric Solid Embryonal Tumors

Induction of caspase 8 by interferon gamma renders some neuroblastoma (NB) cells sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but reveals that a lack of membrane TR1/TR2 also contributes to TRAIL resistance in NB.

scientific article

Insights into pediatric rhabdomyosarcoma research: Challenges and goals

scientific article published on 21 June 2019

Intensified Chemotherapy With Dexrazoxane Cardioprotection in Newly Diagnosed Nonmetastatic Osteosarcoma: A Report From the Children's Oncology Group.

scientific article published on 23 September 2015

Intensity Modulated Radiation Therapy With Dose Painting to Treat Rhabdomyosarcoma ⬇️

scientific article published on November 1, 2012

Intensity-modulated radiation therapy with dose-painting for pediatric sarcomas with pulmonary metastases

scientific article published on 13 June 2013

Intensity-modulated radiotherapy for head-and-neck rhabdomyosarcoma

scientific article published in April 2005

Intracardiac Low-grade Sarcoma Following Treatment for Ewing Sarcoma

scientific article

Irinotecan and temozolomide for Ewing sarcoma: the Memorial Sloan-Kettering experience

scientific article

Irinotecan for pediatric solid tumors: the Memorial Sloan-Kettering experience

scientific article

Late Toxicities of Intensity-Modulated Radiation Therapy for Head and Neck Rhabdomyosarcoma

scientific article published on 16 May 2016

Long-term effect of chemotherapy-intensity-modulated radiation therapy (chemo-IMRT) on dentofacial development in head and neck rhabdomyosarcoma patients

scientific article

Long-term event-free survival after intensive chemotherapy for Ewing's family of tumors in children and young adults.

scientific article published in September 2003

Long-term results of three-dimensional conformal radiation therapy for patients with rhabdomyosarcoma

scientific article published on 01 January 2003

Loss of antibody titers and effectiveness of revaccination in post-chemotherapy pediatric sarcoma patients

scientific article published on 01 October 2007

MYOD1-mutant spindle cell and sclerosing rhabdomyosarcoma: an aggressive subtype irrespective of age. A reappraisal for molecular classification and risk stratification

scientific article published on 04 September 2018

Methotrexate levels and outcome in osteosarcoma

scientific article published in June 2005

Morbidity and mortality after treatment of Ewing sarcoma: A single-institution experience

scientific article published on 18 April 2017

Myeloablative chemotherapy with autologous stem cell transplant for desmoplastic small round cell tumor

scientific article published on 7 April 2015

NTRK3 overexpression in undifferentiated sarcomas with YWHAE and BCOR genetic alterations

scientific article published on 07 February 2020

Novel intraoperative radiotherapy utilizing prefabricated custom three-dimensionally printed high-dose-rate applicators

scientific article published on 22 February 2019

PET for staging in rhabdomyosarcoma: an evaluation of PET as an adjunct to current staging tools.

scientific article

Parameningeal rhabdomyosarcoma: outcomes and opportunities

scientific article published on 25 September 2012

Paratesticular rhabdomyosarcoma: Importance of initial therapy.

scientific article published on 14 November 2016

Patient-derived xenografts for individualized care in advanced sarcoma.

scientific article

Patterns of failure for rhabdomyosarcoma of the perineal and perianal region

scientific article published on 01 May 2014

Pediatric bone sarcoma: diagnostic performance of ¹⁸F-FDG PET/CT versus conventional imaging for initial staging and follow-up

scientific article published in January 2015

Pediatric radical abdominal trachelectomy for anaplastic embryonal rhabdomyosarcoma of the uterine cervix: an alternative to radical hysterectomy

scientific article published on April 2009

Pediatric rhabdomyosarcoma with bone marrow metastasis

scientific article published on 26 February 2020

Phase 1 and pharmacokinetic study of concurrent carboplatin and irinotecan in subjects aged 1 to 21 years with refractory solid tumors.

scientific article

Phase I trial and pharmacokinetic study of lexatumumab in pediatric patients with solid tumors

scientific article

Phase II study of ecteinascidin 743 in heavily pretreated patients with recurrent osteosarcoma

scientific article

Plasma DNA-based molecular diagnosis, prognostication, and monitoring of patients with EWSR1 fusion-positive sarcomas

scientific article published on 23 May 2017

Positron emission tomography (PET) evaluation after initial chemotherapy and radiation therapy predicts local control in rhabdomyosarcoma

scientific article published on 5 May 2012

Predicting outcome in patients with rhabdomyosarcoma: role of [(18)f]fluorodeoxyglucose positron emission tomography

scientific article published on December 2014

Primary Lung Adenocarcinomas in Children and Adolescents Treated for Pediatric Malignancies ⬇️

scientific article published on November 1, 2010

Primary follicular lymphoma of the testis: excellent outcome following surgical resection without adjuvant chemotherapy

scientific article published on February 2004

Radiation for bone metastases in Ewing sarcoma and rhabdomyosarcoma.

scientific article published on 24 October 2014

Radiation therapy for Ewing's sarcoma: results from Memorial Sloan-Kettering in the modern era.

scientific article

Radiotherapy in the multimodal treatment of extrarenal extracranial malignant rhabdoid tumors

scientific article published on 01 January 2008

Recurrent BRAF Gene Fusions in a Subset of Pediatric Spindle Cell Sarcomas: Expanding the Genetic Spectrum of Tumors With Overlapping Features With Infantile Fibrosarcoma

scientific article published on 4 September 2017

Recurrent MYOD1 mutations in pediatric and adult sclerosing and spindle cell rhabdomyosarcomas: evidence for a common pathogenesis

scientific article

Recurrent NCOA2 gene rearrangements in congenital/infantile spindle cell rhabdomyosarcoma

scientific article published on 05 March 2013

Rhabdomyosarcoma: current challenges and their implications for developing therapies.

scientific article

Second cancer risk in childhood cancer survivors treated with intensity-modulated radiation therapy (IMRT).

scientific article

The Memorial Sloan Kettering Cancer Center experience with outpatient administration of high dose methotrexate with leucovorin rescue.

scientific article published on June 2008

The challenging role of radiation therapy for very young children with rhabdomyosarcoma

scientific article published on 06 May 2006

Treatment of osteosarcoma at first recurrence after contemporary therapy: the Memorial Sloan-Kettering Cancer Center experience.

scientific article

Tumour exosome integrins determine organotropic metastasis.

scientific article published on 28 October 2015

Undifferentiated round cell sarcoma with BCOR internal tandem duplications (ITD) or YWHAE fusions: a clinicopathologic and molecular study

scientific article published on 05 May 2020

Undifferentiated small round cell sarcomas with rare EWS gene fusions: identification of a novel EWS-SP3 fusion and of additional cases with the EWS-ETV1 and EWS-FEV fusions

scientific article

Vancomycin-resistant enterococcus in pediatric oncology patients: An analysis of potential consequences of colonization and infection

scientific article published in February 2009

Worse Outcomes for Head and Neck Rhabdomyosarcoma Secondary to Reduced-Dose Cyclophosphamide

scientific article published on 30 November 2018

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