List of works - Sidi Chen

A web tool for the design of prime-editing guide RNAs

scientific article published on 28 September 2020

Diverse Class 2 CRISPR-Cas Effector Proteins for Genome Engineering Applications.

scientific article published on 9 November 2017

Frequent Recent Origination of Brain Genes Shaped the Evolution of Foraging Behavior in Drosophila ⬇️

scientific article published on February 16, 2012

High-content CRISPR screening

scientific article published in 2022

In vivo CRISPR screening in CD8 T cells with AAV-Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma

scientific article published on 23 September 2019

In vivo profiling of metastatic double knockouts through CRISPR-Cpf1 screens

scientific article published on 08 April 2019

Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening

scientific article published on 28 February 2018

Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617

scientific article published on 28 March 2022

Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity

scientific article published on 14 October 2019

Omicron-specific mRNA vaccination alone and as a heterologous booster against SARS-CoV-2

scientific article published on 06 June 2022

One-step generation of modular CAR-T cells with AAV-Cpf1

scientific article published on 25 February 2019

Programmable DNA repair with CRISPRa/i enhanced homology-directed repair efficiency with a single Cas9

scientific article published on 24 July 2018

Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion.

scientific article

Roles of young serine-endopeptidase genes in survival and reproduction revealed rapid evolution of phenotypic effects at adult stages ⬇️

scientific article published on October 1, 2011

Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes