List of works by Fred R Hirsch

"Companion diagnostics": has their time come and gone?

scientific article

"Interchangeability" of PD-L1 immunohistochemistry assays: a meta-analysis of diagnostic accuracy

scientific article published on 05 August 2019

A Definitive Prognostication System for Patients With Thoracic Malignancies Diagnosed With Coronavirus Disease 2019: An Update From the TERAVOLT Registry

scientific article published in 2022

A Grading system for invasive pulmonary adenocarcinoma: a proposal from the IASLC pathology committee

scientific article published on 17 June 2020

A Phase II Study of Telisotuzumab Vedotin in Patients With c-MET-positive Stage IV or Recurrent Squamous Cell Lung Cancer (LUNG-MAP Sub-study S1400K, NCT03574753)

scientific article published on 14 October 2020

A Pilot Study (SWOG S0429) of Weekly Cetuximab and Chest Radiotherapy for Poor-Risk Stage III Non-Small Cell Lung Cancer

scientific article published on 28 August 2013

A Prospective, Multi-institutional, Pathologist-Based Assessment of 4 Immunohistochemistry Assays for PD-L1 Expression in Non-Small Cell Lung Cancer

scientific article published on 09 March 2017

A dramatic response to crizotinib in a non-small-cell lung cancer patient with IHC-positive and FISH-negative ALK.

scientific article

A miRNA Panel Predicts Sensitivity of FGFR Inhibitor in Lung Cancer Cell Lines

scientific article published on 28 June 2018

A new generation of EGFR tyrosine-kinase inhibitors in NSCLC.

scientific article

A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins

scientific article published on 04 April 2013

A phase I/II study of erlotinib in combination with the anti-insulin-like growth factor-1 receptor monoclonal antibody IMC-A12 (cixutumumab) in patients with advanced non-small cell lung cancer

scientific article

A randomized phase II chemoprevention trial of 13-CIS retinoic acid with or without alpha tocopherol or observation in subjects at high risk for lung cancer

scientific article

A randomized, phase II, biomarker-selected study comparing erlotinib to erlotinib intercalated with chemotherapy in first-line therapy for advanced non-small-cell lung cancer

scientific article

Access to Cancer Specialist Care and Treatment in Patients With Advanced Stage Lung Cancer

scientific article published on 26 April 2017

Advances in genomic and proteomic studies of non-small-cell lung cancer: clinical and translational research perspective.

scientific article published on March 2008

An international interpretation study using the ALK IHC antibody D5F3 and a sensitive detection kit demonstrates high concordance between ALK IHC and ALK FISH and between evaluators

scientific article published on May 2014

Analysis of c-ErbB1/epidermal growth factor receptor and c-ErbB2/HER-2 expression in bronchial dysplasia: evaluation of potential targets for chemoprevention of lung cancer

scientific article

Analysis of orthologous gene expression between human pulmonary adenocarcinoma and a carcinogen-induced murine model

scientific article

Antitumor activity of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib (ZD1839, Iressa) in non-small cell lung cancer cell lines correlates with gene copy number and EGFR mutations but not EGFR protein levels

scientific article published on December 2006

Artificial intelligence-based analysis for immunohistochemistry staining of immune checkpoints to predict resected non-small cell lung cancer survival and relapse

scientific article published on 01 June 2021

Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Ca

scientific article published on 2 August 2017

Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in I

scientific article published in September 2017

Assessment of folate receptor-α and epidermal growth factor receptor expression in pemetrexed-treated non-small-cell lung cancer patients

scientific article published on 3 June 2014

Atypical negative ALK break-apart FISH harboring a crizotinib-responsive ALK rearrangement in non-small-cell lung cancer

scientific article published on March 2014

Baseline gene expression predicts sensitivity to gefitinib in non-small cell lung cancer cell lines.

scientific article

Best Practices Recommendations for Diagnostic Immunohistochemistry in Lung Cancer

scientific article published on 18 December 2018

Biological markers for non-small cell lung cancer patient selection for epidermal growth factor receptor tyrosine kinase inhibitor therapy

scientific article published on June 2006

Biomarker Testing for Personalized Therapy in Lung Cancer in Low- and Middle-Income Countries

scientific article

Biomarkers are here to stay for clinical research and standard care

scientific article published on 01 August 2010

Bronchial epithelial Ki-67 index is related to histology, smoking, and gender, but not lung cancer or chronic obstructive pulmonary disease.

scientific article published in November 2007

Bronchioloalveolar carcinoma and lung adenocarcinoma: the clinical importance and research relevance of the 2004 World Health Organization pathologic criteria.

scientific article published on November 2006

Bronchioloalveolar carcinoma: a model for investigating the biology of epidermal growth factor receptor inhibition

scientific article published in June 2004

CD44 Facilitates Epithelial-to-Mesenchymal Transition Phenotypic Change at Acquisition of Resistance to EGFR Kinase Inhibitors in Lung Cancer

scientific article published on 26 July 2018

Cetuximab plus carboplatin and paclitaxel with or without bevacizumab versus carboplatin and paclitaxel with or without bevacizumab in advanced NSCLC (SWOG S0819): a randomised, phase 3 study

scientific article

Challenges in Facing the Lung Cancer Epidemic and Treating Advanced Disease in Latin America

scientific article published on 5 June 2016

Chemotherapy outcomes by histologic subtypes of non-small-cell lung cancer: analysis of the southwest oncology group database for antimicrotubule-platinum therapy

scientific article

Chromosomal abnormalities in non-small cell lung carcinomas and in bronchial epithelia of high-risk smokers detected by multi-target interphase fluorescence in situ hybridization

scientific article published in May 2003

Chromosomal aneusomy in bronchial high-grade lesions is associated with invasive lung cancer

scientific article

Clinical potential of necitumumab in non-small cell lung carcinoma

scientific article

Clinician Perspectives on Current Issues in Lung Cancer Drug Development.

scientific article

Clinicopathologic Features of Advanced Squamous NSCLC.

scientific article published on 10 June 2016

Combined use of oligonucleotide and tissue microarrays identifies cancer/testis antigens as biomarkers in lung carcinoma

scientific article published on July 2002

Comparative expression analysis in small cell lung carcinoma reveals neuroendocrine pattern change in primary tumor versus lymph node metastases

scientific article published on 01 December 2019

Comparison of erlotinib and pemetrexed as second-/third-line treatment for lung adenocarcinoma patients with asymptomatic brain metastases

scientific article published on 21 April 2016

Comprehensive Analysis of EGFR-Mutant Abundance and Its Effect on Efficacy of EGFR TKIs in Advanced NSCLC with EGFR Mutations.

scientific article

Comprehensive Immune Profiling of Medullary Thyroid Cancer

scientific article published on 03 April 2020

Concomitant EGFR Mutation and EML4-ALK Rearrangement in Lung Adenocarcinoma Is More Frequent in Multifocal Lesions

scientific article published on 25 April 2019

Consensus for EGFR mutation testing in non-small cell lung cancer: results from a European workshop

scientific article published on October 2010

Consensus report of a joint NCI thoracic malignancies steering committee: FDA workshop on strategies for integrating biomarkers into clinical development of new therapies for lung cancer leading to the inception of "master protocols" in lung cancer

scientific article

Contributions of KRAS and RAL in non-small-cell lung cancer growth and progression.

scientific article published on December 2013

Coordinated epidermal growth factor receptor pathway gene overexpression predicts epidermal growth factor receptor inhibitor sensitivity in pancreatic cancer

scientific article published in April 2008

Correction: "From Mice to Men and Back: An Assessment of Preclinical Model Systems for the Study of Lung Cancers"

scientific article published on 01 July 2016

Correlation between MET gene copy number by silver in situ hybridization and protein expression by immunohistochemistry in non-small cell lung cancer

scientific article

Correlation of PD-L1 Expression with Tumor Mutation Burden and Gene Signatures for Prognosis in Early-Stage Squamous Cell Lung Carcinoma

scientific article published on 22 September 2018

Current Status and Future Perspectives on Neoadjuvant Therapy in Lung Cancer

scientific article published on 27 September 2018

Current and Emergent Therapy Options for Advanced Squamous-Cell Lung Cancer

scientific article

Current and Future Management of Malignant Mesothelioma : A Consensus Report from the National Cancer Institute Thoracic Malignancy Steering Committee, International Association for the Study of Lung Cancer and Mesothelioma Applied Research Foundatio

scientific article published on 25 September 2018

D4-02: Aneusomy by FISH analysis and histology as predictors of invasive lung cancer in bronchial biopsies from high risk subjects

scientific article

Design of a phase III clinical trial with prospective biomarker validation: SWOG S0819

scientific article

Detection of circulating lung cancer cells with strong thymidylate synthase reactivity in the peripheral blood of a patient with pulmonary adenocarcinoma treated with pemetrexed

scientific article

Developing CT image-processing tools to accelerate progress in lung cancer drug development.

scientific article published on November 2006

Development of an integrated genomic classifier for a novel agent in colorectal cancer: approach to individualized therapy in early development.

scientific article

Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1)

article published in the Proceedings of the National Academy of Sciences of the United States of America

Does selected immunological panel possess the value of predicting the prognosis of early-stage resectable non-small cell lung cancer?

scientific article published on 01 October 2019

Durable brain response with pulse-dose crizotinib and ceritinib in ALK-positive non-small cell lung cancer compared with brain radiotherapy.

scientific article published on 8 December 2015

EGFR Gene Copy Number by FISH May Predict Outcome of Necitumumab in Squamous Lung Carcinomas: Analysis from the SQUIRE Study

scientific article published on 17 November 2017

EGFR and HER2 Gene Copy Number and Response to First-Line Chemotherapy in Patients with Advanced Non-small Cell Lung Cancer (NSCLC)

article

EGFR and HER2 genomic gain in recurrent non-small cell lung cancer after surgery: impact on outcome to treatment with gefitinib and association with EGFR and KRAS mutations in a Japanese cohort

scientific article

EGFR expression and survival in patients given cetuximab and chemoradiation for stage III non-small cell lung cancer: a secondary analysis of RTOG 0324.

scientific article

EGFR expression and the flexibility of FLEX

scientific article published on 04 November 2011

EGFR protein expression in non-small cell lung cancer predicts response to an EGFR tyrosine kinase inhibitor--a novel antibody for immunohistochemistry or AQUA technology

scientific article published on 12 October 2011

EGFR testing in lung cancer is ready for prime time

scientific article (publication date: May 2009)

EGFR tyrosine kinase inhibitors in squamous cell lung cancer.

scientific article published on 5 July 2015

EGFR-TKIs plus local therapy demonstrated survival benefit than EGFR-TKIs alone in EGFR-mutant NSCLC patients with oligometastatic or oligoprogressive liver metastases

scientific article published on 08 December 2018

EGFR-directed monoclonal antibodies in combination with chemotherapy for treatment of non-small-cell lung cancer: an updated review of clinical trials and new perspectives in biomarkers analysis

scientific article published on 04 August 2018

EURACAN/IASLC Proposals for Updating the Histologic Classification of Pleural Mesothelioma: Towards a More Multidisciplinary Approach

scientific article published on 20 September 2019

Early detection and screening of lung cancer ⬇️

scientific article published on September 1, 2010

Effective crizotinib schedule for brain metastases in ALK rearrangement metastatic non-small-cell lung cancer

scientific article published in December 2013

Efficacy and Safety Results From a Phase II, Placebo-Controlled Study of Onartuzumab Plus First-Line Platinum-Doublet Chemotherapy for Advanced Squamous Cell Non-Small-Cell Lung Cancer

scientific article

Endobronchial miRNAs as biomarkers in lung cancer chemoprevention

scientific article

Epidermal Growth Factor Receptor (EGFR) Pathway Biomarkers in the Randomized Phase III Trial of Erlotinib Versus Observation in Ovarian Cancer Patients with No Evidence of Disease Progression after First-Line Platinum-Based Chemotherapy

scientific article

Epidermal growth factor family of receptors in preneoplasia and lung cancer: perspectives for targeted therapies

scientific article

Epidermal growth factor receptor family in lung cancer and premalignancy

scientific article

Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer

scientific article

Epidermal growth factor receptor immunohistochemistry: comparison of antibodies and cutoff points to predict benefit from gefitinib in a phase 3 placebo-controlled study in advanced nonsmall-cell lung cancer.

scientific article

Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis.

scientific article

Epidermal growth factor receptor inhibition in lung cancer: status 2012.

scientific article published on March 2013

Epidermal growth factor receptor inhibitors in lung cancer: smaller or larger molecules, selected or unselected populations?

scientific article

Epidermal growth factor receptor inhibitors plus chemotherapy in non-small-cell lung cancer: biologic rationale for combination strategies

scientific article published on February 2007

Epidermal growth factor receptor messenger RNA expression, gene dosage, and gefitinib sensitivity in non-small cell lung cancer

scientific article

Erratum to: Epidermal Growth Factor Receptor (EGFR) Pathway Biomarkers in the Randomized Phase III Trial of Erlotinib Versus Observation in Ovarian Cancer Patients with No Evidence of Disease Progression after First-Line Platinum-Based Chemotherapy

scientific article published on 8 April 2016

Evolving concepts in the pathology and computed tomography imaging of lung adenocarcinoma and bronchioloalveolar carcinoma

scientific article

Expression of target molecules in lung cancer: challenge for a new treatment paradigm

scientific article

FASTACT-2: but don't act too fast

scientific article published on 17 June 2013

FGFR1 Expression Levels Predict BGJ398 Sensitivity of FGFR1-Dependent Head and Neck Squamous Cell Cancers

scientific article published in October 2015

FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sensitivity across all lung cancer histologies.

scientific article

Fibroblast Growth Factor Receptor 1 and Related Ligands in Small-Cell Lung Cancer

scientific article published on July 2015

Fibroblast growth factor receptor 1 as a putative therapy target in colorectal cancer

scientific article

Finding ALK-positive lung cancer: what are we really looking for?

scientific article published on 01 March 2011

First-generation epidermal growth factor receptor inhibitors in non-small cell lung cancer: clinical impact of the epidermal growth factor receptor fluorescence in situ hybridization assay

scientific article published on June 2008

Fluorescence in situ hybridization subgroup analysis of TRIBUTE, a phase III trial of erlotinib plus carboplatin and paclitaxel in non-small cell lung cancer

scientific article

Fluorescence in situ hybridization, immunohistochemistry, and next-generation sequencing for detection of EML4-ALK rearrangement in lung cancer

scientific article

Folylpoly-glutamate synthetase expression is associated with tumor response and outcome from pemetrexed-based chemotherapy in malignant pleural mesothelioma

scientific article published on September 2012

Forty years of the international association for study of lung cancer pathology committee

scientific article

Frequency and significance of epidermal growth factor receptor mutations detected by PCR methods in patients with non-small cell lung cancer.

scientific article published on 18 March 2019

From Mice to Men and Back: An Assessment of Preclinical Model Systems for the Study of Lung Cancers

scientific article

Functional FLT1 Genetic Variation is a Prognostic Factor for Recurrence in Stage I-III Non-Small-Cell Lung Cancer

scientific article published in July 2015

Galectin-9 in non-small cell lung cancer

scientific article published on 16 August 2019

Gefitinib versus vinorelbine in chemotherapy-naive elderly patients with advanced non-small-cell lung cancer (INVITE): a randomized, phase II study

scientific article

Genetic abnormalities of the EGFR pathway in African American Patients with non-small-cell lung cancer

scientific article published on 28 September 2009

Genomic Testing in Lung Cancer: Past, Present, and Future.

scientific article published in March 2018

HER2/neu expression in malignant lung tumors

scientific article published on February 2002

Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer

scientific article published on 10 April 2013

Hepatic Metastases is Associated with Poor Efficacy of Erlotinib as 2nd/3rd Line Therapy in Patients with Lung Adenocarcinoma.

scientific article published on 26 January 2016

Heterogeneity in Immune Marker Expression after Acquisition of Resistance to EGFR Kinase Inhibitors: Analysis of a Case with Small Cell Lung Cancer Transformation

scientific article published on 10 February 2017

Heterogeneity in Tumors and Resistance to EGFR TKI Therapy-Letter

scientific article published on 2 May 2016

Heterogeneity of EGFR Aberrations and Correlation with Histological Structures: Analyses of Therapy-Naive Isogenic Lung Cancer Lesions with EGFR Mutation

scientific article published on 30 May 2016

High prevalence of endobronchial malignancy in high-risk patients with moderate dysplasia in sputum

scientific article published on 01 May 2004

High prevalence of occult endobronchial malignancy in high risk patients with moderate sputum atypia

scientific article published on 14 April 2005

IASLC Multidisciplinary Recommendations for Pathologic Assessment of Lung Cancer Resection Specimens After Neoadjuvant Therapy

scientific article published on 28 January 2020

IV international conference on prevention and early detection of lung cancer, Reykjavik, Iceland, August 9-12, 2001.

scientific article published in September 2002

Identification of biomarkers in human head and neck tumor cell lines that predict for in vitro sensitivity to gefitinib

scientific article

In Reply

Increased ALK gene copy number and amplification are frequent in non-small cell lung cancer

scientific article

Increased EGFR Phosphorylation Correlates with Higher Programmed Death Ligand-1 Expression: Analysis of TKI-Resistant Lung Cancer Cell Lines

scientific article published on 8 October 2017

Increased EGFR gene copy number detected by fluorescent in situ hybridization predicts outcome in non-small-cell lung cancer patients treated with cetuximab and chemotherapy

scientific article

Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients

scientific article published in August 2005

Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: a Southwest Oncology Group Study

scientific article published on 5 July 2005

Increased epidermal growth factor receptor gene copy number is associated with poor prognosis in head and neck squamous cell carcinomas.

scientific article

Increased insulin-like growth factor 1 receptor protein expression and gene copy number in small cell lung cancer.

scientific article

Incremental Innovation and Progress in Advanced Squamous Cell Lung Cancer: Current Status and Future Impact of Treatment

scientific article published on 26 August 2016

Independent validation test of the vote-counting strategy used to rank biomarkers from published studies

scientific article published on 30 July 2015

Innate Genetic Evolution of Lung Cancers and Spatial Heterogeneity: Analysis of Treatment-Naïve Lesions

scientific article published on 19 June 2018

Insulin-like growth factor receptor 1 (IGF1R) gene copy number is associated with survival in operable non-small-cell lung cancer: a comparison between IGF1R fluorescent in situ hybridization, protein expression, and mRNA expression

scientific article

Insulin-like growth factor-1 receptor (IGF-1R) as a biomarker for resistance to the tyrosine kinase inhibitor gefitinib in non-small cell lung cancer

scientific article

International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society: international multidisciplinary classification of lung adenocarcinoma: executive summary.

scientific article published on September 2011

International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma

scientific article

Interobserver Variation Among Pathologists And Refinement Of Criteria In Distinguishing Separate Primary Tumours From Intrapulmonary Metastases In Lung.

scientific article

Intratumoral Heterogeneity of ALK-Rearranged and ALK/EGFR Coaltered Lung Adenocarcinoma

scientific article published on 28 September 2015

Is there clinical value to prognostic signatures in early-stage NSCLC?

scientific article

KRAS mutations and sensitivity to epidermal growth factor receptor inhibitors in colorectal cancer: practical application of patient selection

scientific article published on 05 January 2009

KRAS mutations and susceptibility to cetuximab and panitumumab in colorectal cancer

scientific article published on March 2009

LAG-3 Protein Expression in Non-Small Cell Lung Cancer and Its Relationship with PD-1/PD-L1 and Tumor-Infiltrating Lymphocytes.

scientific article published on 26 January 2017

Lack of association between sputum atypia and chronic obstructive pulmonary disease mortality

scientific article published on 01 May 2006

Liquid Biopsy for Advanced Non-Small Cell Lung Cancer (NSCLC): A Statement Paper from the IASLC

article

Long non-coding RNA UCA1 induces non-T790M acquired resistance to EGFR-TKIs by activating the AKT/mTOR pathway in EGFR-mutant non-small cell lung cancer

scientific article

Long-term safety and survival with gefitinib in select patients with advanced non-small cell lung cancer: Results from the US IRESSA Clinical Access Program (ICAP).

scientific article

Lung Cancer and Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Identifying Important Knowledge Gaps for Investigation

scientific article

Lung Master Protocol (Lung-MAP)-A Biomarker-Driven Protocol for Accelerating Development of Therapies for Squamous Cell Lung Cancer: SWOG S1400.

scientific article

Lung cancer chemoprevention: moving from concept to a reality

scientific article

Lung cancer in never smokers: molecular profiles and therapeutic implications

scientific article

Lung cancer screening by spiral CT. What is the optimal target population for screening trials?

scientific article published on December 2002

Lung cancer. Introduction

scientific article published on 01 August 2003

Lung cancer: current therapies and new targeted treatments

scientific article

Lymphocyte-activation gene-3, an important immune checkpoint in cancer

scientific article

MAGE A3 antigen-specific cancer immunotherapeutic

scientific article published on January 2009

MHC class II expression in lung cancer.

scientific article published on 29 July 2017

MINI01.15: Prophylactic Cranial Irradiation (PCI) for Limited Small Cell Lung Cancer (LSCLC): An IASLC Physician Survey: Topic: Radiation Oncology.

scientific article published on 28 October 2016

Mass spectrometry to classify non-small-cell lung cancer patients for clinical outcome after treatment with epidermal growth factor receptor tyrosine kinase inhibitors: a multicohort cross-institutional study.

scientific article published in June 2007

Molecular Testing for Treatment of Metastatic Non-Small Cell Lung Cancer: How to Implement Evidence-Based Recommendations

scientific article

Molecular and Immune Biomarker Testing in Squamous-Cell Lung Cancer: Effect of Current and Future Therapies and Technologies

scientific article published on 21 March 2018

Molecular predictors of outcome with gefitinib in a phase III placebo-controlled study in advanced non-small-cell lung cancer

scientific article published on 01 November 2006

Molecularly targeted therapy: when to stop and when to continue?

scientific article published on 01 August 2010

Multi-institutional prospective validation of prognostic mRNA signatures in early stage squamous lung cancer (Alliance)

scientific article published on 24 July 2020

Multi-target interphase fluorescence in situ hybridization assay increases sensitivity of sputum cytology as a predictor of lung cancer

scientific article published on 01 January 2004

National Lung Cancer Screening Trial American College of Radiology Imaging Network Specimen Biorepository originating from the Contemporary Screening for the Detection of Lung Cancer Trial (NLST, ACRIN 6654): design, intent, and availability of [...]

scientific article

Neuroendocrine subtypes of small cell lung cancer differ in terms of immune microenvironment and checkpoint molecule distribution

scientific article published on 07 June 2020

New and emerging targeted treatments in advanced non-small-cell lung cancer.

scientific article published on September 2016

Next-generation sequencing identifies and immunohistochemistry confirms a novel crizotinib-sensitive ALK rearrangement in a patient with metastatic non-small-cell lung cancer.

scientific article published on September 2012

Nivolumab Plus Ipilimumab vs Nivolumab for Previously Treated Patients With Stage IV Squamous Cell Lung Cancer: The Lung-MAP S1400I Phase 3 Randomized Clinical Trial

scientific article published on 01 September 2021

Novel epidermal growth factor receptor mutation-specific antibodies for non-small cell lung cancer: immunohistochemistry as a possible screening method for epidermal growth factor receptor mutations

scientific article

Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer

scientific article

ORAL01.01: A Prospective, Multi-Institutional Assessment of Four Assays for PD-L1 Expression in NSCLC by Immunohistochemistry: Topic: Pathology.

scientific article

OX40 and OX40L protein expression of tumor infiltrating lymphocytes in non-small cell lung cancer and its role in clinical outcome and relationships with other immune biomarkers

scientific article published on 01 August 2019

Oral iloprost improves endobronchial dysplasia in former smokers

scientific article published on June 2011

Overcoming resistance to EGFR tyrosine kinase inhibitors in lung cancer, focusing on non-T790M mechanisms

scientific article published on 13 July 2017

PD-1, PD-L1 Protein Expression in Non-Small Cell Lung Cancer and Their Relationship with Tumor-Infiltrating Lymphocytes.

scientific article published on 09 March 2017

PD-L1 Expression by Two Complementary Diagnostic Assays and mRNA In Situ Hybridization in Small Cell Lung Cancer

scientific article published on 14 September 2016

PD-L1 Expression in Lung Cancer

scientific article published on 23 April 2016

PD-L1 Immunohistochemistry Assays for Lung Cancer: Results from Phase 1 of the Blueprint PD-L1 IHC Assay Comparison Project

scientific article published on 29 November 2016

PD-L1 Immunohistochemistry Comparability Study in Real-Life Clinical Samples: Results of Blueprint Phase 2 Project

article by Ming-Sound Tsao et al published September 2018 in Journal of Thoracic Oncology

PD-L1 Testing for Lung Cancer in 2019: Perspective From the IASLC Pathology Committee

scientific article published on 20 December 2019

PTPRF Expression as a Potential Prognostic/Predictive Marker for Treatment with Erlotinib in Non-Small-Cell Lung Cancer

scientific article published on September 2015

Paired Phase II Studies of Erlotinib/Bevacizumab for Advanced Bronchioloalveolar Carcinoma or Never Smokers With Advanced Non-Small-cell Lung Cancer: SWOG S0635 and S0636 Trials

scientific article published on 06 July 2017

Pathologic Diagnosis of Advanced Lung Cancer Based on Small Biopsies and Cytology: A Paradigm Shift

scientific article published on 01 April 2010

Patient selection criteria and the FLEX Study

scientific article published in May 2009

Persistence of Bronchial Dysplasia Is Associated with Development of Invasive Squamous Cell Carcinoma

scientific article

Phase I study of vandetanib with radiation therapy with or without cisplatin in locally advanced head and neck squamous cell carcinoma

scientific article published on 29 October 2014

Phase II selection design trial of concurrent chemotherapy and cetuximab versus chemotherapy followed by cetuximab in advanced-stage non-small-cell lung cancer: Southwest Oncology Group study S0342

scientific article

Phase II trial of carboplatin, paclitaxel, cetuximab, and bevacizumab followed by cetuximab and bevacizumab in advanced nonsquamous non-small-cell lung cancer: SWOG S0536

scientific article

Physician Bias in Prophylactic Cranial Irradiation Decision Making-An Opportunity for a Patient Decision Aid.

scientific article published on 17 February 2018

Postprogression Prolongation of Survival in EGFR-Mutated Lung Cancer: Reconciling the ASPIRATION and IMPRESS Trials

scientific article published on 30 December 2015

Potential effect of spliceosome inhibition in small cell lung cancer irrespective of the MYC status

scientific article

Potential future consideration for imaging and blood-based biomarkers for precision medicine in lung cancer

scientific article published in December 2017

Preclinical studies of gemcitabine and trastuzumab in breast and lung cancer cell lines.

scientific article

Predictive and prognostic markers for epidermal growth factor receptor inhibitor therapy in non-small cell lung cancer

scientific article

Predictive value of epidermal growth factor receptor expression for first-line chemotherapy plus cetuximab in patients with head and neck and colorectal cancer: analysis of data from the EXTREME and CRYSTAL studies

scientific article

Primary Double-Strike Therapy for Cancers to Overcome EGFR Kinase Inhibitor Resistance: Proposal from the Bench

scientific article published on 15 September 2016

Programmed Cell Death Ligand 1 Expression in Resected Non-Small Cell Lung Cancer

scientific article published on 15 October 2020

Programmed Death Ligand-1 Immunohistochemistry: Friend or Foe?

scientific article published on 12 January 2016

Programmed Death-Ligand 1 Immunohistochemistry in Lung Cancer: In what state is this art?

scientific article published on July 2015

Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort

scientific article published on 01 March 2006

RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer.

scientific article published on 8 November 2017

ROS1 immunohistochemistry among major genotypes of non-small-cell lung cancer

scientific article published on 24 October 2014

Radiologic Considerations and Standardization of Malignant Pleural Mesothelioma Imaging Within Clinical Trials: Consensus Statement from the NCI Thoracic Malignancy Steering Committee - International Association for the Study of Lung Cancer - Mesoth

scientific article published on 27 August 2019

Randomized phase II study of gefitinib compared with placebo in chemotherapy-naive patients with advanced non-small-cell lung cancer and poor performance status

scientific article published on 16 March 2009

Randomized phase II trial of erlotinib with and without entinostat in patients with advanced non-small-cell lung cancer who progressed on prior chemotherapy

scientific article published on 16 April 2012

Randomized, placebo-controlled window trial of EGFR, Src, or combined blockade in head and neck cancer

scientific article published on 23 March 2017

Reanalysis of the NCCN PD-L1 companion diagnostic assay study for lung cancer in the context of PD-L1 expression findings in triple-negative breast cancer.

scientific article

Recent developments in biomarkers for the early detection of lung cancer: perspectives based on publications 2003 to present

scientific article published in July 2004

Recurrent genomic gains in preinvasive lesions as a biomarker of risk for lung cancer

scientific article

Reproducibility of histopathological diagnosis in poorly differentiated NSCLC: an international multiobserver study

scientific article published in September 2014

Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines.

scientific article published on January 2006

Round Robin Evaluation of MET Protein Expression in Lung Adenocarcinomas Improves Interobserver Concordance

scientific article published on 22 November 2019

SWOG S0709: Randomized Phase II Trial of Erlotinib versus Erlotinib Plus Carboplatin/Paclitaxel in Patients with Advanced Non-Small Cell Lung Cancer and Impaired Performance Status as Selected by a Serum Proteomics Assay

scientific article published on 24 December 2015

Scientific Advances and New Frontiers in Mesothelioma Therapeutics

scientific article published on 01 September 2018

Scientific Advances in Lung Cancer 2015.

scientific article published on 21 March 2016

Scientific Advances in Thoracic Oncology 2016.

scientific article published on 27 May 2017

Selecting lung cancer patients for treatment with epidermal growth factor receptor tyrosine kinase inhibitors by immunohistochemistry and fluorescence in situ hybridization--why, when, and how?

scientific article published on July 2006

Serum microRNAs improving the diagnostic accuracy in lung cancer presenting with pulmonary nodules

article published in 2018

Seven-microRNA panel for lung adenocarcinoma early diagnosis in patients presenting with ground-glass nodules

scientific article published on 13 December 2017

Significance of folate receptor alpha and thymidylate synthase protein expression in patients with non-small-cell lung cancer treated with pemetrexed

scientific article published on January 2013

Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?

scientific article published on 29 January 2016

Southwest Oncology Group phase II trial (S0341) of erlotinib (OSI-774) in patients with advanced non-small cell lung cancer and a performance status of 2.

scientific article

Southwestern oncology group phase II trial (S0526) of pemetrexed in bronchioloalveolar carcinoma subtypes of advanced adenocarcinoma

scientific article

Spectral karyotyping detects chromosome damage in bronchial cells of smokers and patients with cancer

scientific article

Sputum cytologic atypia predicts incident lung cancer: defining latency and histologic specificity

scientific article published on 01 January 2008

Sputum cytological atypia as a predictor of incident lung cancer in a cohort of heavy smokers with airflow obstruction ⬇️

scientific article published on 01 October 2003

Summary statement novel agents in the treatment of lung cancer: Fifth Cambridge Conference assessing opportunities for combination therapy

scientific article published on 01 June 2008

Systemic therapy of advanced bronchioloalveolar cell carcinoma: challenges and opportunities

scientific article

T cell immunoglobulin and mucin-domain containing-3 in non-small cell lung cancer

scientific article published on 01 December 2019

TIM-3, a promising target for cancer immunotherapy

Targeted molecular mechanisms of epoetin alfa

scientific article

Targeting BRAF mutations in non-small cell lung cancer

scientific article published on 01 December 2019

Targeting anemia in patients with lung cancer.

scientific article published on September 2006

The 2015 World Health Organization Classification of Lung Tumors: Impact of Genetic, Clinical and Radiologic Advances Since the 2004 Classification

scientific article published in September 2015

The Armed Conflict and the Impact on Patients With Cancer in Ukraine: Urgent Considerations

scientific article published in 2022

The E-cadherin cell-cell adhesion complex and lung cancer invasion, metastasis, and prognosis

scientific article

The International Association Study Lung Cancer (IASLC) Strategic Screening Advisory Committee (SSAC) response to the USPSTF recommendations

scientific article published in February 2014

The International Association for the Study of Lung Cancer (IASLC) Global Survey on Molecular Testing in Lung Cancer

scientific article published on 14 May 2020

The International Association for the Study of Lung Cancer Consensus Statement on Optimizing Management of EGFR Mutation-Positive Non-Small Cell Lung Cancer: Status in 2016.

scientific article published on 20 May 2016

The International Association for the Study of Lung Cancer Early Lung Imaging Confederation

scientific article published on 01 February 2020

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of non-small cell lung cancer (NSCLC).

scientific article published on 17 July 2018

The Tissue Is the Issue: Personalized Medicine for Non-Small Cell Lung Cancer ⬇️

scientific article published on 05 October 2010

The Use of Radiation Therapy for the Treatment of Malignant Pleural Mesothelioma: Expert Opinion from the National Cancer Institute Thoracic Malignancy Steering Committee, International Association for the Study of Lung Cancer, and Mesothelioma Appl

scientific article published on 22 May 2019

The biology of epidermal growth factor receptor in lung cancer

scientific article published in June 2004

The bronchioloalveolar carcinoma and peripheral adenocarcinoma spectrum of diseases.

scientific article published on May 2006

The detection of chromosomal aneusomy by fluorescence in situ hybridization in sputum predicts lung cancer incidence

scientific article

The insulin-like growth factor pathway in lung cancer

scientific article published on August 2008

The mTOR pathway in lung cancer and implications for therapy and biomarker analysis

scientific article published on June 2012

The prognostic and predictive role of histology in advanced non-small cell lung cancer: a literature review

scientific article published on December 2008

The rationale and development of therapeutic insulin-like growth factor axis inhibition for lung and other cancers

scientific article published on July 2009

The role of HER2/neu expression and trastuzumab in non-small cell lung cancer

scientific article published on February 2004

Therapy-induced E-cadherin downregulation alters expression of programmed death ligand-1 in lung cancer cells

scientific article published on 19 April 2017

Three-arm, randomized, phase 2 study of carboplatin and paclitaxel in combination with cetuximab, cixutumumab, or both for advanced non-small cell lung cancer (NSCLC) patients who will not receive bevacizumab-based therapy: An Eastern Cooperative On

scientific article

Thymidylate synthase protein expression by IHC and gene copy number by SISH correlate and show great variability in non-small cell lung cancer

scientific article published on June 2012

Tobacco money: up in smoke?

scientific article published in December 2002

Treatment of advanced non-small-cell lung cancer with epidermal growth factor receptor (EGFR) mutation or ALK gene rearrangement: results of an international expert panel meeting of the Italian Association of Thoracic Oncology

scientific article published on 27 December 2013

Tumor Mutation Burden: Promises and Challenges A Perspective from the IASLC Pathology Committee

scientific article published on 06 June 2020

Unusual chemosensitivity of advanced bronchioalveolar carcinoma after gefitinib response and progression: a case report

scientific article published on 01 January 2007

Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors: Guideline From the College of American Pathologists, the International Association for the Study of Lung Cancer, an

scientific article published on 22 January 2018

Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors: Guideline From the College of American Pathologists, the International Association for the Study of Lung Cancer, an

scientific article published on 23 January 2018

Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors: Guideline From the College of American Pathologists, the International Association for the Study of Lung Cancer, an

scientific article published on 23 January 2018

Using molecular markers in sputum for the early detection of lung cancer: a review

scientific article

What is the role of HER-2/neu and trastuzumab (Herceptin) in lung cancer?

scientific article published on 01 June 2002

c-MET as a biomarker in patients with surgically resected non-small cell lung cancer

scientific article published on 01 May 2019

cMET Exon 14 Skipping: From the Structure to the Clinic.

scientific article published on 17 May 2016

sLAG-3 in non-small-cell lung cancer patients' serum

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