List of works - Anna Bal-Price

A human pluripotent carcinoma stem cell-based model for in vitro developmental neurotoxicity testing: effects of methylmercury, lead and aluminum evaluated by gene expression studies

scientific article published on 13 March 2013

A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing.

scientific article published on 29 March 2016

Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems

scientific article published on 13 April 2018

Advancing human health risk assessment

scientific article published on 08 July 2019

Adverse outcome pathways: Application to enhance mechanistic understanding of neurotoxicity

scientific article

Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.

scientific article

An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition.

scientific article

An analysis of the limitations and uncertainties of in vivo developmental neurotoxicity testing and assessment to identify the potential for alternative approaches

scientific article published on 08 August 2020

Assessment of developmental neurotoxicity induced by chemical mixtures using an adverse outcome pathway concept

scientific article published on 24 February 2020

Brain-on-a-chip model enables analysis of human neuronal differentiation and chemotaxis

scientific article published in October 2016

Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

scientific article published on 12 February 2018

Corrigendum to Recommendation on test readiness criteria for new approach methods in toxicology: exemplified for developmental neurotoxicity

scientific article published on 01 January 2019

Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity

scientific article

Development and analysis of an adverse outcome pathway network for human neurotoxicity

scientific article published on 23 August 2019

Development of a mechanistically-based genetically engineered PC12 cell system to detect p53-mediated cytotoxicity

scientific article published on 20 December 2006

Development of the Adverse Outcome Pathway (AOP): Chronic binding of antagonist to N-methyl-d-aspartate receptors (NMDARs) during brain development induces impairment of learning and memory abilities of children

scientific article published on 7 March 2018

Developmental neurotoxicity testing: recommendations for developing alternative methods for the screening and prioritization of chemicals.

scientific article published on January 2011

Early life exposure to air pollution particulate matter (PM) as risk factor for attention deficit/hyperactivity disorder (ADHD): Need for novel strategies for mechanisms and causalities

scientific article published on 14 March 2018

Editorial: Developmental neurotoxicity

scientific article published on 17 July 2018

Evaluation of drug-induced neurotoxicity based on metabolomics, proteomics and electrical activity measurements in complementary CNS in vitro models

scientific article

Evaluation of the rotenone-induced activation of the Nrf2 pathway in a neuronal model derived from human induced pluripotent stem cells

scientific article

Gene expression as a sensitive endpoint to evaluate cell differentiation and maturation of the developing central nervous system in primary cultures of rat cerebellar granule cells (CGCs) exposed to pesticides

scientific article published on 25 December 2008

Genomic and phenotypic alterations of the neuronal-like cells derived from human embryonal carcinoma stem cells (NT2) caused by exposure to organophosphorus compounds paraoxon and mipafox

scientific article published on 09 January 2014

Good Cell Culture Practice for stem cells and stem-cell-derived models.

scientific article published on 23 August 2016

Good Cell and Tissue Culture Practice 2.0 (GCCP 2.0) - Draft for stakeholder discussion and call for action

scientific article published on 01 January 2020

Guidance on good cell culture practice. a report of the second ECVAM task force on good cell culture practice

scientific article published on 01 June 2005

Highly purified lipoteichoic acid induced pro-inflammatory signalling in primary culture of rat microglia through Toll-like receptor 2: selective potentiation of nitric oxide production by muramyl dipeptide

scientific article published on 31 July 2006

Inflammatory neurodegeneration induced by lipoteichoic acid from Staphylococcus aureus is mediated by glia activation, nitrosative and oxidative stress, and caspase activation

scientific article

Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria

scientific article

Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death

scientific journal article

Integrating biokinetics and in vitro studies to evaluate developmental neurotoxicity induced by chlorpyrifos in human iPSC-derived neural stem cells undergoing differentiation towards neuronal and glial cells

scientific article published on 01 October 2020

International Regulatory and Scientific Effort for Improved Developmental Neurotoxicity Testing

scientific article published on 01 January 2019

International STakeholder NETwork (ISTNET) for creating a developmental neurotoxicity testing (DNT) roadmap for regulatory purposes

scientific article published in January 2014

International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes

scientific article

Investigating cell type specific mechanisms contributing to acute oral toxicity

scientific article published on 12 July 2018

Investigation into experimental toxicological properties of plant protection products having a potential link to Parkinson's disease and childhood leukaemia†

scientific article published in March 2017

Mechanisms of toxicity induced by SiO2 nanoparticles of in vitro human alveolar barrier: effects on cytokine production, oxidative stress induction, surfactant proteins A mRNA expression and nanoparticles uptake.

scientific article

Message from the Editor-in-Chief

scientific article published on 16 November 2019

Nitric oxide induces rapid, calcium-dependent release of vesicular glutamate and ATP from cultured rat astrocytes

scientific article published in December 2002

Nitric oxide stimulates PC12 cell proliferation via cGMP and inhibits at higher concentrations mainly via energy depletion

scientific article

Nrf2 pathway activation upon rotenone treatment in human iPSC-derived neural stem cells undergoing differentiation towards neurons and astrocytes

scientific article published on 13 June 2017

OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes.

scientific article published in January 2017

Overcoming barriers to validation of non-animal partial replacement methods/Integrated Testing Strategies: the report of an EPAA-ECVAM workshop.

scientific article published in September 2009

Protocol for the Differentiation of Human Induced Pluripotent Stem Cells into Mixed Cultures of Neurons and Glia for Neurotoxicity Testing

scientific article published on 9 June 2017

Putative adverse outcome pathways relevant to neurotoxicity

scientific article

Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity

scientific article published on 23 February 2018

Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.

scientific article

Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways

scientific article published on 01 June 2018

Stimulation of the NADPH oxidase in activated rat microglia removes nitric oxide but induces peroxynitrite production

scientific article published in January 2002

Strategies to improve the regulatory assessment of developmental neurotoxicity (DNT) using in vitro methods

scientific article published on 21 February 2018

The value of alternative testing for neurotoxicity in the context of regulatory needs ⬇️

scientific article published on August 24, 2005

Workgroup report: incorporating in vitro alternative methods for developmental neurotoxicity into international hazard and risk assessment strategies

scientific article published on 6 February 2007

mRNA expression is a relevant tool to identify developmental neurotoxicants using an in vitro approach

scientific article published on 3 August 2009

miRNA expression profiling in a human stem cell-based model as a tool for developmental neurotoxicity testing

scientific article published on August 2013

List of works by Anna Bal-Price

A human pluripotent carcinoma stem cell-based model for in vitro developmental neurotoxicity testing: effects of methylmercury, lead and aluminum evaluated by gene expression studies

A multi-laboratory evaluation of microelectrode array-based measurements of neural network activity for acute neurotoxicity testing.

Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems

Advancing human health risk assessment

Adverse outcome pathways: Application to enhance mechanistic understanding of neurotoxicity

Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.

An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition.

An analysis of the limitations and uncertainties of in vivo developmental neurotoxicity testing and assessment to identify the potential for alternative approaches

Assessment of developmental neurotoxicity induced by chemical mixtures using an adverse outcome pathway concept

Brain-on-a-chip model enables analysis of human neuronal differentiation and chemotaxis

Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

Corrigendum to Recommendation on test readiness criteria for new approach methods in toxicology: exemplified for developmental neurotoxicity

Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity

Development and analysis of an adverse outcome pathway network for human neurotoxicity

Development of a mechanistically-based genetically engineered PC12 cell system to detect p53-mediated cytotoxicity

Development of the Adverse Outcome Pathway (AOP): Chronic binding of antagonist to N-methyl-d-aspartate receptors (NMDARs) during brain development induces impairment of learning and memory abilities of children

Developmental neurotoxicity testing: recommendations for developing alternative methods for the screening and prioritization of chemicals.

Early life exposure to air pollution particulate matter (PM) as risk factor for attention deficit/hyperactivity disorder (ADHD): Need for novel strategies for mechanisms and causalities

Editorial: Developmental neurotoxicity

Evaluation of drug-induced neurotoxicity based on metabolomics, proteomics and electrical activity measurements in complementary CNS in vitro models

Evaluation of the rotenone-induced activation of the Nrf2 pathway in a neuronal model derived from human induced pluripotent stem cells

Gene expression as a sensitive endpoint to evaluate cell differentiation and maturation of the developing central nervous system in primary cultures of rat cerebellar granule cells (CGCs) exposed to pesticides

Genomic and phenotypic alterations of the neuronal-like cells derived from human embryonal carcinoma stem cells (NT2) caused by exposure to organophosphorus compounds paraoxon and mipafox

Good Cell Culture Practice for stem cells and stem-cell-derived models.

Good Cell and Tissue Culture Practice 2.0 (GCCP 2.0) - Draft for stakeholder discussion and call for action

Guidance on good cell culture practice. a report of the second ECVAM task force on good cell culture practice

Highly purified lipoteichoic acid induced pro-inflammatory signalling in primary culture of rat microglia through Toll-like receptor 2: selective potentiation of nitric oxide production by muramyl dipeptide

Inflammatory neurodegeneration induced by lipoteichoic acid from Staphylococcus aureus is mediated by glia activation, nitrosative and oxidative stress, and caspase activation

Inflammatory neurodegeneration mediated by nitric oxide, glutamate, and mitochondria

Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death

Integrating biokinetics and in vitro studies to evaluate developmental neurotoxicity induced by chlorpyrifos in human iPSC-derived neural stem cells undergoing differentiation towards neuronal and glial cells

International Regulatory and Scientific Effort for Improved Developmental Neurotoxicity Testing

International STakeholder NETwork (ISTNET) for creating a developmental neurotoxicity testing (DNT) roadmap for regulatory purposes

International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes

Investigating cell type specific mechanisms contributing to acute oral toxicity

Investigation into experimental toxicological properties of plant protection products having a potential link to Parkinson's disease and childhood leukaemia†

Mechanisms of toxicity induced by SiO2 nanoparticles of in vitro human alveolar barrier: effects on cytokine production, oxidative stress induction, surfactant proteins A mRNA expression and nanoparticles uptake.

Message from the Editor-in-Chief

Nitric oxide induces rapid, calcium-dependent release of vesicular glutamate and ATP from cultured rat astrocytes

Nitric oxide stimulates PC12 cell proliferation via cGMP and inhibits at higher concentrations mainly via energy depletion

Nrf2 pathway activation upon rotenone treatment in human iPSC-derived neural stem cells undergoing differentiation towards neurons and astrocytes

OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes.

Overcoming barriers to validation of non-animal partial replacement methods/Integrated Testing Strategies: the report of an EPAA-ECVAM workshop.

Protocol for the Differentiation of Human Induced Pluripotent Stem Cells into Mixed Cultures of Neurons and Glia for Neurotoxicity Testing

Putative adverse outcome pathways relevant to neurotoxicity

Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity

Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.

Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways

Stimulation of the NADPH oxidase in activated rat microglia removes nitric oxide but induces peroxynitrite production

Strategies to improve the regulatory assessment of developmental neurotoxicity (DNT) using in vitro methods

The value of alternative testing for neurotoxicity in the context of regulatory needs ⬇️

Workgroup report: incorporating in vitro alternative methods for developmental neurotoxicity into international hazard and risk assessment strategies

mRNA expression is a relevant tool to identify developmental neurotoxicants using an in vitro approach

miRNA expression profiling in a human stem cell-based model as a tool for developmental neurotoxicity testing