List of works - David J. Miller

6- and 14-Fluoro farnesyl diphosphate: mechanistic probes for the reaction catalysed by aristolochene synthase

scientific article published on 20 January 2009

A 1,6-ring closure mechanism for (+)-δ-cadinene synthase?

scientific article published on 19 March 2012

An unexpected co-crystal structure of the calpain PEF(S) domain with Hfq reveals a potential chaperone function of Hfq

scientific article published on 05 February 2020

Aristolochene synthase-catalyzed cyclization of 2-fluorofarnesyl-diphosphate to 2-fluorogermacrene A.

scientific article published in October 2007

Calpain-1 inhibitors for selective treatment of rheumatoid arthritis: what is the future?

scientific article

Chemoenzymatic preparation of germacrene analogues ⬇️

scientific article published on October 9, 2012

Chemoenzymatic synthesis of the alarm pheromone (+)-verbenone from geranyl diphosphate

scientific article

Competitive inhibition of aristolochene synthase by phenyl-substituted farnesyl diphosphates: evidence of active site plasticity

scientific article published on 14 September 2007

Crystal Structure of (+)-δ-Cadinene Synthase from Gossypium arboreum and Evolutionary Divergence of Metal Binding Motifs for Catalysis

scientific article

Designed high affinity Cu2+-binding alpha-helical foldamer

scientific article

Harnessing enzyme plasticity for the synthesis of oxygenated sesquiterpenoids

scientific article published on 17 September 2019

Mechanism of Germacradien-4-ol Synthase-Controlled Water Capture.

scientific article published on 21 March 2016

Novel olfactory ligands via terpene synthases.

scientific article published in May 2015

Nucleophilic Water Capture or Proton Loss: Single Amino Acid Switch Converts δ-Cadinene Synthase into Germacradien-4-ol Synthase.

scientific article

Probing the reaction mechanism of aristolochene synthase with 12,13-difluorofarnesyl diphosphate

scientific article published on 6 August 2007

Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency

scientific article

Removal of the phosphate group in mechanism-based inhibitors of inositol monophosphatase leads to unusual inhibitory activity

scientific article published on 5 February 2004

Sesquiterpene Synthase-Catalysed Formation of a New Medium-Sized Cyclic Terpenoid Ether from Farnesyl Diphosphate Analogues

scientific article published on 16 July 2018

Sesquiterpene Synthase-Catalyzed Conversion of a Farnesyl Diphosphate Analogue to a Nonnatural Terpenoid Ether

scientific article published on 06 July 2018

Silent catalytic promiscuity in the high-fidelity terpene cyclase δ-cadinene synthase

scientific article published on 01 January 2019

Stereochemistry of eudesmane cation formation during catalysis by aristolochene synthase from Penicillium roqueforti

scientific article published on 28 April 2008

Structure-based design of allosteric calpain-1 inhibitors populating a novel bioactivity space

scientific article published on 23 August 2018

The structural basis of differential inhibition of human calpain by indole and phenyl α-mercaptoacrylic acids

scientific article

X-ray Crystallographic Studies of Substrate Binding to Aristolochene Synthase Suggest a Metal Ion Binding Sequence for Catalysis

scientific article

List of works by David J. Miller

6- and 14-Fluoro farnesyl diphosphate: mechanistic probes for the reaction catalysed by aristolochene synthase

A 1,6-ring closure mechanism for (+)-δ-cadinene synthase?

An unexpected co-crystal structure of the calpain PEF(S) domain with Hfq reveals a potential chaperone function of Hfq

Aristolochene synthase-catalyzed cyclization of 2-fluorofarnesyl-diphosphate to 2-fluorogermacrene A.

Calpain-1 inhibitors for selective treatment of rheumatoid arthritis: what is the future?

Chemoenzymatic preparation of germacrene analogues ⬇️

Chemoenzymatic synthesis of the alarm pheromone (+)-verbenone from geranyl diphosphate

Competitive inhibition of aristolochene synthase by phenyl-substituted farnesyl diphosphates: evidence of active site plasticity

Crystal Structure of (+)-δ-Cadinene Synthase from Gossypium arboreum and Evolutionary Divergence of Metal Binding Motifs for Catalysis

Designed high affinity Cu2+-binding alpha-helical foldamer

Harnessing enzyme plasticity for the synthesis of oxygenated sesquiterpenoids

Mechanism of Germacradien-4-ol Synthase-Controlled Water Capture.

Novel olfactory ligands via terpene synthases.

Nucleophilic Water Capture or Proton Loss: Single Amino Acid Switch Converts δ-Cadinene Synthase into Germacradien-4-ol Synthase.

Probing the reaction mechanism of aristolochene synthase with 12,13-difluorofarnesyl diphosphate

Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency

Removal of the phosphate group in mechanism-based inhibitors of inositol monophosphatase leads to unusual inhibitory activity

Sesquiterpene Synthase-Catalysed Formation of a New Medium-Sized Cyclic Terpenoid Ether from Farnesyl Diphosphate Analogues

Sesquiterpene Synthase-Catalyzed Conversion of a Farnesyl Diphosphate Analogue to a Nonnatural Terpenoid Ether

Silent catalytic promiscuity in the high-fidelity terpene cyclase δ-cadinene synthase

Stereochemistry of eudesmane cation formation during catalysis by aristolochene synthase from Penicillium roqueforti

Structure-based design of allosteric calpain-1 inhibitors populating a novel bioactivity space

The structural basis of differential inhibition of human calpain by indole and phenyl α-mercaptoacrylic acids

X-ray Crystallographic Studies of Substrate Binding to Aristolochene Synthase Suggest a Metal Ion Binding Sequence for Catalysis