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List of works by John W Mellors

A pilot study to determine the impact on dyslipidemia of adding tenofovir to stable background antiretroviral therapy: ACTG 5206.

scientific article

A9 A method to obtain full-length HIV proviral sequences and their sites of integration

ART suppresses plasma HIV-1 RNA to a stable set point predicted by pretherapy viremia

scientific article

Amplifying and quantifying HIV-1 RNA in HIV infected individuals with viral loads below the limit of detection by standard clinical assays

scientific article published on 26 September 2011

Analysis of 454 sequencing error rate, error sources, and artifact recombination for detection of Low-frequency drug resistance mutations in HIV-1 DNA.

scientific article published on 13 February 2013

Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size

scientific article published on 12 April 2019

Baseline natural killer and T cell populations correlation with virologic outcome after regimen simplification to atazanavir/ritonavir alone (ACTG 5201).

scientific article

Blockade of the PD-1 axis alone is not sufficient to activate HIV-1 virion production from CD4+ T cells of individuals on suppressive ART

scientific article published in PLoS ONE

Clonal resistance analyses of HIV type-1 after failure of therapy with didanosine, lamivudine and tenofovir

scientific article

Clonally expanded CD4+ T cells can produce infectious HIV-1 in vivo

scientific article published on 8 February 2016

Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors

scientific article published on 27 November 2019

Correction: Performance of Swabs, Lavage, and Diluents to Quantify Biomarkers of Female Genital Tract Soluble Mucosal Mediators.

scientific article published on 26 January 2012

Correction: Prevalence of HIV-1 Drug Resistance among Women Screening for HIV Prevention Trials in KwaZulu-Natal, South Africa (MTN-009)

scientific article (publication date: 6 January 2014)

Correction: The Effect of Raltegravir Intensification on Low-level Residual Viremia in HIV-Infected Patients on Antiretroviral Therapy: A Randomized Controlled Trial.

scientific article published on 4 August 2011

Depletion of latent HIV-1 infection in vivo: a proof-of-concept study

scientific article (publication date: August 2005)

Dynamics of immune reconstitution and activation markers in HIV+ treatment-naïve patients treated with raltegravir, tenofovir disoproxil fumarate and emtricitabine

scientific article

E138A in HIV-1 reverse transcriptase is more common in subtype C than B: implications for rilpivirine use in resource-limited settings

scientific article

Early Emergence and Long-Term Persistence of HIV-Infected T-Cell Clones in Children

scientific article

Factors influencing the emergence and spread of HIV drug resistance arising from rollout of antiretroviral pre-exposure prophylaxis (PrEP)

scientific article

Frequent polymorphism at drug resistance sites in HIV-1 protease and reverse transcriptase

scientific article

Genetic diversity of simian immunodeficiency virus encoding HIV-1 reverse transcriptase persists in macaques despite antiretroviral therapy

scientific article

HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus

scientific article published on 01 October 2019

HIV-1 continues to replicate and evolve in patients with natural control of HIV infection

scientific article

HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy

scientific article published on 30 July 2019

HIV-1 infection leads to increased transcription of human endogenous retrovirus HERV-K (HML-2) proviruses in vivo but not to increased virion production

scientific article

HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study.

scientific article published on 7 November 2017

Histone deacetylase inhibitor romidepsin induces HIV expression in CD4 T cells from patients on suppressive antiretroviral therapy at concentrations achieved by clinical dosing

scientific article

How Much Do We Know about Drug Resistance Due to PrEP Use? Analysis of Experts' Opinion and Its Influence on the Projected Public Health Impact

scientific article

How Much HIV is Alive? The Challenge of Measuring Replication Competent HIV for HIV Cure Research

scientific article

In vitro activity of structurally diverse nucleoside analogs against human immunodeficiency virus type 1 with the K65R mutation in reverse transcriptase

scientific article

In vitro selection and analysis of human immunodeficiency virus type 1 resistant to derivatives of beta-2',3'-didehydro-2',3'-dideoxy-5-fluorocytidine

scientific article

Insertional activation of <i>STAT3</i> and <i>LCK</i> by HIV-1 proviruses in T cell lymphomas

scientific article published on 13 October 2021

Lack of detectable HIV-1 molecular evolution during suppressive antiretroviral therapy

scientific article

Levels of HIV-1 persistence on antiretroviral therapy are not associated with markers of inflammation or activation.

scientific article

Low frequency nonnucleoside reverse-transcriptase inhibitor-resistant variants contribute to failure of efavirenz-containing regimens in treatment- experienced patients

scientific article

Low-level viremia persists for at least 7 years in patients on suppressive antiretroviral therapy

scholarly article

Lower pre-ART intra-participant HIV-1 pol diversity may not be associated with virologic failure in adults

scientific article

Lytic granule loading of CD8+ T cells is required for HIV-infected cell elimination associated with immune control

scientific article published on 08 December 2008

Majority of CD4+ T cells from peripheral blood of HIV-1-infected individuals contain only one HIV DNA molecule

scientific article

Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: balance between RNase H activity and nucleotide excision

scientific article

Multi-dose Romidepsin Reactivates Replication Competent SIV in Post-antiretroviral Rhesus Macaque Controllers

scientific article (publication date: September 2016)

Multiple sources of contamination in samples from patients reported to have XMRV infection

scientific article (publication date: 2012)

Multiple, linked human immunodeficiency virus type 1 drug resistance mutations in treatment-experienced patients are missed by standard genotype analysis

scientific article

Nevirapine- versus lopinavir/ritonavir-based initial therapy for HIV-1 infection among women in Africa: a randomized trial

scientific article

New Tools for Quantifying HIV-1 Reservoirs: Plasma RNA Single Copy Assays and Beyond ⬇️

scientific article published on March 1, 2012

New real-time reverse transcriptase-initiated PCR assay with single-copy sensitivity for human immunodeficiency virus type 1 RNA in plasma

scientific article published on October 2003

No effect of raltegravir intensification on viral replication markers in the blood of HIV-1-infected patients receiving antiretroviral therapy

scientific article

No evidence of HIV replication in children on antiretroviral therapy.

scientific article published on 11 September 2017

Ongoing HIV Replication During ART Reconsidered

article

Origin of Rebound Plasma HIV Includes Cells with Identical Proviruses That Are Transcriptionally Active before Stopping of Antiretroviral Therapy

scientific article

PAPNC, a novel method to calculate nucleotide diversity from large scale next generation sequencing data

scientific article

Performance of swabs, lavage, and diluents to quantify biomarkers of female genital tract soluble mucosal mediators

scientific article

Persistence of viral reservoirs in multiple tissues after antiretroviral therapy suppression in a macaque RT-SHIV model

scientific article (publication date: 2013)

Planning for pre-exposure prophylaxis to prevent HIV transmission: challenges and opportunities

scientific article

Potential impact of antiretroviral chemoprophylaxis on HIV-1 transmission in resource-limited settings

scientific article

Prevalence of HIV-1 Drug Resistance among Women Screening for HIV Prevention Trials in KwaZulu-Natal, South Africa (MTN-009) ⬇️

scientific article published on April 9, 2013

Proceedings of the Frontiers of Retrovirology Conference 2016.

scientific article published on 26 September 2016

Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir

scientific article

Quantification of HIV-1 latency reversal in resting CD4+ T cells from patients on suppressive antiretroviral therapy

scientific article

RT-SHIV subpopulation dynamics in infected macaques during anti-HIV therapy

scientific article

Regimen simplification to atazanavir-ritonavir alone as maintenance antiretroviral therapy: final 48-week clinical and virologic outcomes

scientific article published on March 2009

Single cell analysis of lymph node tissue from HIV-1 infected patients reveals that the majority of CD4+ T-cells contain one HIV-1 DNA molecule

scientific article

Single-cell analysis of HIV-1 transcriptional activity reveals expression of proviruses in expanded clones during ART.

scientific article published on 17 April 2017

Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapy

scientific article

The effect of raltegravir intensification on low-level residual viremia in HIV-infected patients on antiretroviral therapy: a randomized controlled trial

scientific article

Therapeutic Vaccination With Dendritic Cells Loaded With Autologous HIV Type 1-Infected Apoptotic Cells

scientific article published on 8 December 2015

Towards an HIV cure: a global scientific strategy

scientific article

Ultrasensitive allele-specific PCR reveals rare preexisting drug-resistant variants and a large replicating virus population in macaques infected with a simian immunodeficiency virus containing human immunodeficiency virus reverse transcriptase

scientific article

Ultrasensitive single-genome sequencing: accurate, targeted, next generation sequencing of HIV-1 RNA.

scientific article

Well-mixed plasma and tissue viral populations in RT-SHIV-infected macaques implies a lack of viral replication in the tissues during antiretroviral therapy

scientific article

Y chromosome and HIV DNA detection in vaginal swabs as biomarkers of semen and HIV exposure in women

scientific article

YKL-40, a marker of simian immunodeficiency virus encephalitis, modulates the biological activity of basic fibroblast growth factor

scientific article

Zidovudine (AZT) Monotherapy Selects for the A360V Mutation in the Connection Domain of HIV-1 Reverse Transcriptase ⬇️

scientific article published on February 21, 2012

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