List of works - Kunihiko Nishino

13-(2-Methylbenzyl) Berberine Is a More Potent Inhibitor of MexXY-Dependent Aminoglycoside Resistance than Berberine

scientific article published on 06 November 2019

AcrA dependency of the AcrD efflux pump in Salmonella enterica serovar Typhimurium ⬇️

scientific article published on April 20, 2011

AcrAB multidrug efflux pump regulation in Salmonella enterica serovar Typhimurium by RamA in response to environmental signals

scientific article published on 24 June 2008

AcrB-AcrA Fusion Proteins That Act as Multidrug Efflux Transporters

scientific article

AcrS/EnvR represses expression of the acrAB multidrug efflux genes in Escherichia coli

scientific article published on 20 June 2008

An efflux inhibitor of the MacAB pump in Salmonella enterica serovar Typhimurium

scientific article published on 27 January 2020

Berberine Is a Novel Type Efflux Inhibitor Which Attenuates the MexXY-Mediated Aminoglycoside Resistance in Pseudomonas aeruginosa

scientific article published on 05 August 2016

Beta-lactam resistance modulated by the overexpression of response regulators of two-component signal transduction systems in Escherichia coli

scientific article published on 01 September 2003

Bile-mediated activation of the acrAB and tolC multidrug efflux genes occurs mainly through transcriptional derepression of ramA in Salmonella enterica serovar Typhimurium

scientific article published on 9 May 2014

CRP regulator modulates multidrug resistance of Escherichia coli by repressing the mdtEF multidrug efflux genes

scientific article published in March 2008

Comprehensive studies of drug resistance mediated by overexpression of response regulators of two-component signal transduction systems in Escherichia coli

scientific article

Cooperation of the multidrug efflux pump and lipopolysaccharides in the intrinsic antibiotic resistance of Salmonella enterica serovar Typhimurium

scientific article

Correction: Streptococcus pneumoniae Invades Erythrocytes and Utilizes Them to Evade Human Innate Immunity.

scientific article published on 15 January 2014

Crystal structure of the multidrug resistance regulator RamR complexed with bile acids

scientific article published in Scientific Reports

Crystal structures of multidrug efflux pump MexB bound with high-molecular-mass compounds

scientific article published on 13 March 2019

Development of a structure determination method using a multidrug-resistance regulator protein as a framework

scientific article published on 17 August 2019

Dissecting the PhoP regulatory network of Escherichia coli and Salmonella enterica

scientific article

Effect of NlpE overproduction on multidrug resistance in Escherichia coli

scientific article

Effect of methylglyoxal on multidrug-resistant Pseudomonas aeruginosa.

scientific article

Effect of overexpression of small non-coding DsrA RNA on multidrug efflux in Escherichia coli ⬇️

scientific article published on November 18, 2010

Effects of efflux transporter genes on susceptibility of Escherichia coli to tigecycline (GAR-936).

scientific article

Effects of indole on drug resistance and virulence of Salmonella enterica serovar Typhimurium revealed by genome-wide analyses.

scientific article

Effects of natural mutations in the ramRA locus on invasiveness of epidemic fluoroquinolone-resistant Salmonella enterica serovar Typhimurium isolates.

scientific article published on 10 December 2012

EvgA of the two-component signal transduction system modulates production of the yhiUV multidrug transporter in Escherichia coli

scientific article published on April 2002

Frontier of Pharmaceutical Microbiology: To Combat Multidrug-resistant Bacterial Pathogens

scientific article

Genome-wide analyses of Escherichia coli gene expression responsive to the BaeSR two-component regulatory system

scientific article

Global analysis of genes regulated by EvgA of the two-component regulatory system in Escherichia coli

scientific article

Growth phase-dependent expression of drug exporters in Escherichia coli and its contribution to drug tolerance

scientific article published on August 2006

H-NS modulates multidrug resistance of Salmonella enterica serovar Typhimurium by repressing multidrug efflux genes acrEF.

scientific article published on 08 June 2009

Hoisting-Loop in Bacterial Multidrug Exporter AcrB Is a Highly Flexible Hinge That Enables the Large Motion of the Subdomains.

scientific article

Identification of Genetic Variants <i>via</i> Bacterial Respiration Gas Analysis

scientific article published on 16 November 2020

Identification of a spermidine excretion protein complex (MdtJI) in Escherichia coli.

scientific article

Impact of hfq on the intrinsic drug resistance of salmonella enterica serovar typhimurium

scientific article

Impact of the RNA chaperone Hfq on multidrug resistance in Escherichia coli

scientific article published on 7 March 2010

Indole enhances acid resistance in Escherichia coli

scientific article published on 12 May 2010

Membrane topology of ABC-type macrolide antibiotic exporter MacB in Escherichia coli

scientific article published in July 2003

Multidrug efflux pumps contribute to Escherichia coli biofilm maintenance.

scientific article

Multiple entry pathways within the efflux transporter AcrB contribute to multidrug recognition.

scientific article published on 9 January 2018

N-acetyl-d-glucosamine induces the expression of multidrug exporter genes, mdtEF, via catabolite activation in Escherichia coli

scientific article published on August 2006

Native CRISPR-Cas-Mediated Genome Editing Enables Dissecting and Sensitizing Clinical Multidrug-Resistant P. aeruginosa

scientific article published on 01 November 2019

Phenotype microarray analysis of the drug efflux systems in Salmonella enterica serovar Typhimurium.

scientific article

Phylogenetic and functional characterisation of the Haemophilus influenzae multidrug efflux pump AcrB

scientific article published on 13 September 2019

Proximal Binding Pocket Arg717 Substitutions in Escherichia coli AcrB Cause Clinically Relevant Divergencies in Resistance Profiles

scientific article published in 2022

Regulation and physiological function of multidrug efflux pumps in Escherichia coli and Salmonella

scientific article published on 20 February 2009

Regulation of multidrug efflux systems involved in multidrug and metal resistance of Salmonella enterica serovar Typhimurium

scientific article

Regulation of the AcrAB multidrug efflux pump in Salmonella enterica serovar Typhimurium in response to indole and paraquat ⬇️

scientific article published on December 9, 2010

Role of histone-like protein H-NS in multidrug resistance of Escherichia coli

scientific article published on March 2004

Role of the AraC-XylS family regulator YdeO in multi-drug resistance of Escherichia coli

scientific article

Roles of Salmonella multidrug efflux pumps in tigecycline resistance ⬇️

scientific article published on November 16, 2010

Roles of TolC-dependent multidrug transporters of Escherichia coli in resistance to beta-lactams

scientific article published on September 2003

Salmonella enterica serovar Typhimurium multidrug efflux pumps EmrAB and AcrEF support the major efflux system AcrAB in decreased susceptibility to triclosan

scientific article published on 12 June 2014

Streptococcus pneumoniae invades erythrocytes and utilizes them to evade human innate immunity

scientific article

Structural Analysis and New Drug Development against Multidrug Efflux Pumps

scientific article published on January 2017

Structural basis for the inhibition of bacterial multidrug exporters ⬇️

scientific article published on June 30, 2013

Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket ⬇️

scientific article published on November 27, 2011

The AraC-family regulator GadX enhances multidrug resistance in Escherichia coli by activating expression of mdtEF multidrug efflux genes

scientific article

The crystal structure of multidrug-resistance regulator RamR with multiple drugs

scientific article

The putative response regulator BaeR stimulates multidrug resistance of Escherichia coli via a novel multidrug exporter system, MdtABC

scientific article published on August 2002

TolC dependency of multidrug efflux systems in Salmonella enterica serovar Typhimurium

scientific article published on 22 May 2010

Virulence and drug resistance roles of multidrug efflux systems of Salmonella enterica serovar Typhimurium

scientific article published in January 2006

[Role of drug efflux pumps in bacterial multidrug resistance and virulence. Analysis to identify novel drug targets and counteract multidrug resistance and virulence]

scientific article published on 01 April 2008

List of works by Kunihiko Nishino

13-(2-Methylbenzyl) Berberine Is a More Potent Inhibitor of MexXY-Dependent Aminoglycoside Resistance than Berberine

AcrA dependency of the AcrD efflux pump in Salmonella enterica serovar Typhimurium ⬇️

AcrAB multidrug efflux pump regulation in Salmonella enterica serovar Typhimurium by RamA in response to environmental signals

AcrB-AcrA Fusion Proteins That Act as Multidrug Efflux Transporters

AcrS/EnvR represses expression of the acrAB multidrug efflux genes in Escherichia coli

An efflux inhibitor of the MacAB pump in Salmonella enterica serovar Typhimurium

Berberine Is a Novel Type Efflux Inhibitor Which Attenuates the MexXY-Mediated Aminoglycoside Resistance in Pseudomonas aeruginosa

Beta-lactam resistance modulated by the overexpression of response regulators of two-component signal transduction systems in Escherichia coli

Bile-mediated activation of the acrAB and tolC multidrug efflux genes occurs mainly through transcriptional derepression of ramA in Salmonella enterica serovar Typhimurium

CRP regulator modulates multidrug resistance of Escherichia coli by repressing the mdtEF multidrug efflux genes

Comprehensive studies of drug resistance mediated by overexpression of response regulators of two-component signal transduction systems in Escherichia coli

Cooperation of the multidrug efflux pump and lipopolysaccharides in the intrinsic antibiotic resistance of Salmonella enterica serovar Typhimurium

Correction: Streptococcus pneumoniae Invades Erythrocytes and Utilizes Them to Evade Human Innate Immunity.

Crystal structure of the multidrug resistance regulator RamR complexed with bile acids

Crystal structures of multidrug efflux pump MexB bound with high-molecular-mass compounds

Development of a structure determination method using a multidrug-resistance regulator protein as a framework

Dissecting the PhoP regulatory network of Escherichia coli and Salmonella enterica

Effect of NlpE overproduction on multidrug resistance in Escherichia coli

Effect of methylglyoxal on multidrug-resistant Pseudomonas aeruginosa.

Effect of overexpression of small non-coding DsrA RNA on multidrug efflux in Escherichia coli ⬇️

Effects of efflux transporter genes on susceptibility of Escherichia coli to tigecycline (GAR-936).

Effects of indole on drug resistance and virulence of Salmonella enterica serovar Typhimurium revealed by genome-wide analyses.

Effects of natural mutations in the ramRA locus on invasiveness of epidemic fluoroquinolone-resistant Salmonella enterica serovar Typhimurium isolates.

EvgA of the two-component signal transduction system modulates production of the yhiUV multidrug transporter in Escherichia coli

Frontier of Pharmaceutical Microbiology: To Combat Multidrug-resistant Bacterial Pathogens

Genome-wide analyses of Escherichia coli gene expression responsive to the BaeSR two-component regulatory system

Global analysis of genes regulated by EvgA of the two-component regulatory system in Escherichia coli

Growth phase-dependent expression of drug exporters in Escherichia coli and its contribution to drug tolerance

H-NS modulates multidrug resistance of Salmonella enterica serovar Typhimurium by repressing multidrug efflux genes acrEF.

Hoisting-Loop in Bacterial Multidrug Exporter AcrB Is a Highly Flexible Hinge That Enables the Large Motion of the Subdomains.

Identification of Genetic Variants <i>via</i> Bacterial Respiration Gas Analysis

Identification of a spermidine excretion protein complex (MdtJI) in Escherichia coli.

Impact of hfq on the intrinsic drug resistance of salmonella enterica serovar typhimurium

Impact of the RNA chaperone Hfq on multidrug resistance in Escherichia coli

Indole enhances acid resistance in Escherichia coli

Membrane topology of ABC-type macrolide antibiotic exporter MacB in Escherichia coli

Multidrug efflux pumps contribute to Escherichia coli biofilm maintenance.

Multiple entry pathways within the efflux transporter AcrB contribute to multidrug recognition.

N-acetyl-d-glucosamine induces the expression of multidrug exporter genes, mdtEF, via catabolite activation in Escherichia coli

Native CRISPR-Cas-Mediated Genome Editing Enables Dissecting and Sensitizing Clinical Multidrug-Resistant P. aeruginosa

Phenotype microarray analysis of the drug efflux systems in Salmonella enterica serovar Typhimurium.

Phylogenetic and functional characterisation of the Haemophilus influenzae multidrug efflux pump AcrB

Proximal Binding Pocket Arg717 Substitutions in Escherichia coli AcrB Cause Clinically Relevant Divergencies in Resistance Profiles

Regulation and physiological function of multidrug efflux pumps in Escherichia coli and Salmonella

Regulation of multidrug efflux systems involved in multidrug and metal resistance of Salmonella enterica serovar Typhimurium

Regulation of the AcrAB multidrug efflux pump in Salmonella enterica serovar Typhimurium in response to indole and paraquat ⬇️

Role of histone-like protein H-NS in multidrug resistance of Escherichia coli

Role of the AraC-XylS family regulator YdeO in multi-drug resistance of Escherichia coli

Roles of Salmonella multidrug efflux pumps in tigecycline resistance ⬇️

Roles of TolC-dependent multidrug transporters of Escherichia coli in resistance to beta-lactams

Salmonella enterica serovar Typhimurium multidrug efflux pumps EmrAB and AcrEF support the major efflux system AcrAB in decreased susceptibility to triclosan

Streptococcus pneumoniae invades erythrocytes and utilizes them to evade human innate immunity

Structural Analysis and New Drug Development against Multidrug Efflux Pumps

Structural basis for the inhibition of bacterial multidrug exporters ⬇️

Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket ⬇️

The AraC-family regulator GadX enhances multidrug resistance in Escherichia coli by activating expression of mdtEF multidrug efflux genes

The crystal structure of multidrug-resistance regulator RamR with multiple drugs

The putative response regulator BaeR stimulates multidrug resistance of Escherichia coli via a novel multidrug exporter system, MdtABC

TolC dependency of multidrug efflux systems in Salmonella enterica serovar Typhimurium

Virulence and drug resistance roles of multidrug efflux systems of Salmonella enterica serovar Typhimurium

[Role of drug efflux pumps in bacterial multidrug resistance and virulence. Analysis to identify novel drug targets and counteract multidrug resistance and virulence]