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List of works by Yingshan Han

A high-throughput assay for HIV-1 integrase 3'-processing activity using time-resolved fluorescence.

scientific article

A resveratrol analog termed 3,3',4,4',5,5'-hexahydroxy-trans-stilbene is a potent HIV-1 inhibitor

scientific article published on 18 May 2015

Addition of E138K to R263K in HIV integrase increases resistance to dolutegravir, but fails to restore activity of the HIV integrase enzyme and viral replication capacity.

scientific article

Antimalarial drugs and their metabolites are potent Zika virus inhibitors

scientific article published on 04 March 2019

Biochemical Analysis of the Role of G118R-Linked Dolutegravir Drug Resistance Substitutions in HIV-1 Integrase.

scientific article published in January 2014

Biochemical Analysis of the Role of G118R-Linked Dolutegravir Drug Resistance Substitutions in HIV-1 Integrase.

scientific article published in June 2014

Biochemical analysis of the role of G118R-linked dolutegravir drug resistance substitutions in HIV-1 integrase

scientific article published on 30 September 2013

Characterization of the R263K mutation in HIV-1 integrase that confers low-level resistance to the second-generation integrase strand transfer inhibitor dolutegravir

scientific article

Development of a fluorescence-based HIV-1 integrase DNA binding assay for identification of novel HIV-1 integrase inhibitors.

scientific article

Differences among HIV-1 subtypes in drug resistance against integrase inhibitors

scientific article published on 25 June 2016

Differential effects of the G118R, H51Y, and E138K resistance substitutions in different subtypes of HIV integrase

scientific article

Erratum for Mesplède et al., "The R263K Dolutegravir Resistance-Associated Substitution Progressively Decreases HIV-1 Integration"

article

HIV-1 group O integrase displays lower enzymatic efficiency and higher susceptibility to raltegravir than HIV-1 group M subtype B integrase

scientific article

Identification of a dibenzocyclooctadiene lignan as a HIV-1 non-nucleoside reverse transcriptase inhibitor

scientific article published on February 2015

Might dolutegravir be part of a functional cure for HIV?

scientific article

Neuroprotective effects of resveratrol against beta-amyloid-induced neurotoxicity in rat hippocampal neurons: involvement of protein kinase C

scientific article

Structural Studies of the HIV-1 Integrase Protein: Compound Screening and Characterization of a DNA-Binding Inhibitor

scientific article

The M50I polymorphic substitution in association with the R263K mutation in HIV-1 subtype B integrase increases drug resistance but does not restore viral replicative fitness

scientific article published on 17 January 2014

The R263K substitution in HIV-1 subtype C is more deleterious for integrase enzymatic function and viral replication than in subtype B.

scientific article published on July 2015

The antimalarial drug amodiaquine possesses anti-ZIKA virus activities.

scientific article published on 9 January 2018

Viral fitness cost prevents HIV-1 from evading dolutegravir drug pressure

scientific article published on 22 February 2013

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