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List of works by Hai Yu

9-Azido-9-deoxy-2,3-difluorosialic Acid as a Subnanomolar Inhibitor against Bacterial Sialidases

scientific article published on 24 May 2019

A Bacterial β1-3-Galactosyltransferase Enables Multigram-Scale Synthesis of Human Milk Lacto-<i>N</i>-tetraose (LNT) and Its Fucosides

scientific article published on 24 October 2019

A Chemoenzymatic Synthon Strategy for Synthesizing N-Acetyl Analogues of O-Acetylated N. meningitidis W Capsular Polysaccharide Oligosaccharides

scientific article published on 09 November 2020

A diazido mannose analog as a chemoenzymatic synthon for synthesizing di-N-acetyllegionaminic acid-containing glycosides.

scientific article published on 19 January 2018

An optics-based variable-temperature assay system for characterizing thermodynamics of biomolecular reactions on solid support

scientific article published on November 2013

Biochemical characterization of Helicobacter pylori α1-3-fucosyltransferase and its application in the synthesis of fucosylated human milk oligosaccharides

scientific article published on 16 May 2019

Biomimetic Glyconanoparticle Vaccine for Cancer Immunotherapy

scientific article published on 11 March 2019

Catalytic Cycle of Neisseria meningitidis CMP-Sialic Acid Synthetase Illustrated by High-Resolution Protein Crystallography

scientific article published on 04 October 2019

Characterization of Receptor Binding Profiles of Influenza A Viruses Using An Ellipsometry-Based Label-Free Glycan Microarray Assay Platform.

scientific article

Chemoenzymatic synthesis of C8-modified sialic acids and related α2-3- and α2-6-linked sialosides.

scientific article

Chemoenzymatic synthesis of Neu5Ac9NAc-containing α2-3- and α2-6-linked sialosides and their use for sialidase substrate specificity studies

scientific article published on 18 September 2017

Chemoenzymatic synthesis of sialosides containing C7-modified sialic acids and their application in sialidase substrate specificity studies

scientific article

Cloning and characterization of a viral α2-3-sialyltransferase (vST3Gal-I) for the synthesis of sialyl Lewisx

scientific article

Crystal structures of sialyltransferase from Photobacterium damselae

scientific article

Decreasing the sialidase activity of multifunctional Pasteurella multocida α2-3-sialyltransferase 1 (PmST1) by site-directed mutagenesis

scientific article

Differential Recognition of Diet-Derived Neu5Gc-Neoantigens on Glycan Microarrays by Carbohydrate-Specific Pooled Human IgG and IgA Antibodies

scientific article published on 24 April 2019

Directed Evolution of Therapeutic Antibodies Targeting Glycosylation in Cancer

scientific article published on 30 September 2020

Donor substrate promiscuity of bacterial β1-3-N-acetylglucosaminyltransferases and acceptor substrate flexibility of β1-4-galactosyltransferases

scientific article

Donor substrate promiscuity of the N-acetylglucosaminyltransferase activities of Pasteurella multocida heparosan synthase 2 (PmHS2) and Escherichia coli K5 KfiA ⬇️

scientific article published on May 10, 2013

Effective one-pot multienzyme (OPME) synthesis of monotreme milk oligosaccharides and other sialosides containing 4-O-acetyl sialic acid

scientific article published on 22 August 2016

Efficient Chemoenzymatic Synthesis of an N-glycan Isomer Library

scientific article published on 23 June 2015

Efficient chemoenzymatic synthesis of sialyl Tn-antigens and derivatives

scientific article published on July 2011

Efficient one-pot multienzyme synthesis of UDP-sugars using a promiscuous UDP-sugar pyrophosphorylase from Bifidobacterium longum (BLUSP).

scientific article published on 3 February 2012

Exploring the Impact of Ketodeoxynonulosonic Acid in Host-Pathogen Interactions Using Uptake and Surface Display by Nontypeable Haemophilus influenzae

scientific article published in 2021

Fluorescent labeling agents change binding profiles of glycan-binding proteins

scientific article

Helicobacter hepaticus Hh0072 gene encodes a novel alpha1-3-fucosyltransferase belonging to CAZy GT11 family

scientific article published on 6 May 2010

High-throughput neuraminidase substrate specificity study of human and avian influenza A viruses

scientific article

Highly efficient chemoenzymatic synthesis of β1-3-linked galactosides.

scientific article published on 10 September 2010

Highly efficient one-pot multienzyme (OPME) synthesis of glycans with fluorous-tag assisted purification

scientific article published on 29 January 2014

Identifying selective inhibitors against the human cytosolic sialidase NEU2 by substrate specificity studies.

scientific article published on 4 January 2011

Improved one-pot multienzyme (OPME) systems for synthesizing UDP-uronic acids and glucuronides

scientific article

L. pneumophila CMP-5,7-di-N-acetyllegionaminic acid synthetase (LpCLS)-involved chemoenzymatic synthesis of sialosides and analogues

scientific article published on 08 January 2020

Multifunctionality of Campylobacter jejuni sialyltransferase CstII: characterization of GD3/GT3 oligosaccharide synthase, GD3 oligosaccharide sialidase, and trans-sialidase activities.

scientific article published on 28 May 2008

One-pot multi-enzyme (OPME) chemoenzymatic synthesis of sialyl-Tn-MUC1 and sialyl-T-MUC1 glycopeptides containing natural or non-natural sialic acid

scientific article published on 7 March 2013

One-pot multienzyme synthesis of Lewis x and sialyl Lewis x antigens

scientific article published on September 2012

One-pot three-enzyme synthesis of UDP-GlcNAc derivatives ⬇️

scientific article published on August 23, 2011

Pasteurella multocida CMP-sialic acid synthetase and mutants of Neisseria meningitidis CMP-sialic acid synthetase with improved substrate promiscuity

scientific article published on 4 October 2011

Pasteurella multocida sialic acid aldolase: a promising biocatalyst

scientific article published on 03 June 2008

PmST3 from Pasteurella multocida encoded by Pm1174 gene is a monofunctional α2-3-sialyltransferase

scientific article published on 11 November 2011

Polyclonal human antibodies against glycans bearing red meat-derived non-human sialic acid N-glycolylneuraminic acid are stable, reproducible, complex and vary between individuals: Total antibody levels are associated with colorectal cancer risk.

scientific article published on 18 June 2018

Presentation Mode of Glycans Affect Recognition of Human Serum anti-Neu5Gc IgG Antibodies

scientific article published on 13 December 2018

Probe sialidase substrate specificity using chemoenzymatically synthesized sialosides containing C9-modified sialic acid

scientific article

Production of functional mimics of human milk oligosaccharides by enzymatic glycosylation of bovine milk oligosaccharides

scientific article published on 13 November 2019

Regioselective One-Pot Multienzyme (OPME) Chemoenzymatic Strategies for Systematic Synthesis of Sialyl Core 2 Glycans

scientific article published on 05 December 2018

Sequential One-Pot Multienzyme Chemoenzymatic Synthesis of Glycosphingolipid Glycans

scientific article

Sialidase substrate specificity studies using chemoenzymatically synthesized sialosides containing C5-modified sialic acids.

scientific article published on 26 October 2009

Size-Controlled Chemoenzymatic Synthesis of Homogeneous Oligosaccharides of <i>Neisseria meningitidis</i> W Capsular Polysaccharide

scientific article published on 07 February 2020

Streptococcus pneumoniae Sialidase SpNanB-Catalyzed One-Pot Multienzyme (OPME) Synthesis of 2,7-Anhydro-Sialic Acids as Selective Sialidase Inhibitors

scientific article published on 23 August 2018

Structural Basis for Substrate Specificity and Mechanism of N -Acetyl- d -neuraminic Acid Lyase from Pasteurella multocida

scientific article

Structural characterization of a nonhydrolyzing UDP-GlcNAc 2-epimerase from Neisseria meningitidis serogroup A

scientific article published on 29 October 2020

Substrate promiscuity of N-acetylhexosamine 1-kinases

scientific article published on 28 July 2011

Synthesis of selective inhibitors against V. cholerae sialidase and human cytosolic sialidase NEU2.

scientific article

Synthetic disialyl hexasaccharides protect neonatal rats from necrotizing enterocolitis

scientific article

Tailored design and synthesis of heparan sulfate oligosaccharide analogues using sequential one-pot multienzyme systems

scientific article published on 13 September 2013

The Hd0053 gene of Haemophilus ducreyi encodes an alpha2,3-sialyltransferase

scientific article published on 23 July 2007

The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication

scientific article published on 21 February 2020

Trans-sialidase activity of Photobacterium damsela alpha2,6-sialyltransferase and its application in the synthesis of sialosides

scientific article published on 30 October 2009

Triazole-linked transition state analogs as selective inhibitors against V. cholerae sialidase

scientific article published on 27 October 2018

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