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List of works by Xavier Nassif

3D structure/function analysis of PilX reveals how minor pilins can modulate the virulence properties of type IV pili

scientific article

A cell-contact-regulated operon is involved in genetic variability in Neisseria meningitidis

scientific article published on 21 December 2011

A chromosomally integrated bacteriophage in invasive meningococci ⬇️

scientific article

A journey into the brain: insight into how bacterial pathogens cross blood-brain barriers

scientific article published on 16 January 2017

A new family of secreted toxins in pathogenic Neisseria species

scientific article

A splenic IgM memory subset with antibacterial specificities is sustained from persistent mucosal responses

article

A systematic genetic analysis in Neisseria meningitidis defines the Pil proteins required for assembly, functionality, stabilization and export of type IV pili

article by Etienne Carbonnelle et al published September 2006 in Molecular Microbiology

A two-component system is required for colonization of host cells by meningococcus.

scientific article published on 23 April 2009

A uropathogenicity island contributes to the pathogenicity of Escherichia coli strains that cause neonatal meningitis

scientific article published on October 2002

A virulence-associated filamentous bacteriophage of Neisseria meningitidis increases host-cell colonisation.

scientific article published on 13 July 2017

A widespread family of polymorphic toxins encoded by temperate phages.

scientific article published on 29 August 2017

About the usefulness of contact precautions for carriers of extended-spectrum beta-lactamase-producing Escherichia coli

scientific article published on 12 November 2015

Airway Mucus Restricts Neisseria meningitidis Away from Nasopharyngeal Epithelial Cells and Protects the Mucosa from Inflammation

scientific article published on 04 December 2019

Alternative Neisseria spp. type IV pilin glycosylation with a glyceramido acetamido trideoxyhexose residue

scientific article

An ADAM-10 dependent EPCR shedding links meningococcal interaction with endothelial cells to purpura fulminans.

scientific article published on 9 April 2018

Antibacterial Toxins: Gram-Positive Bacteria Strike Back!

scientific article published on 21 November 2017

Applications of MALDI-TOF-MS in clinical microbiology laboratory

scientific article

Association of a bacteriophage with meningococcal disease in young adults.

scientific article

Bacterial pathogens associated with hidradenitis suppurativa, France

scientific article

Bacteriophages and pathogenicity: more than just providing a toxin?

scientific article

Breaking the wall: targeting of the endothelium by pathogenic bacteria

scientific article published on 30 December 2009

Cerebral microcirculation shear stress levels determine Neisseria meningitidis attachment sites along the blood-brain barrier

scientific article

Cerebral microcirculation shear stress levels determineNeisseria meningitidisattachment sites along the blood–brain barrier

Characterization of MDAΦ, a temperate filamentous bacteriophage of Neisseria meningitidis.

scientific article published on 24 November 2015

Childhood meningitis. Current data on physiopathology

scientific article published on June 27, 1998

Chronic Staphylococcus aureus Lung Infection Correlates With Proteogenomic and Metabolic Adaptations Leading to an Increased Intracellular Persistence

scientific article published on 01 November 2019

Chronic meningococcemia cutaneous lesions involve meningococcal perivascular invasion through the remodeling of endothelial barriers.

scientific article published on 12 March 2012

Clonal relationship and differentiation among Mycobacterium abscessus isolates as determined using the semiautomated repetitive extragenic palindromic sequence PCR-based DiversiLab system

scientific article

Community-Onset Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Invasive Infections in Children in a University Hospital in France ⬇️

scientific article published on March 2016

Comparative genomics identifies the genetic islands that distinguish Neisseria meningitidis, the agent of cerebrospinal meningitis, from other Neisseria species

scientific article published on December 2002

Comprehensive Identification of Meningococcal Genes and Small Noncoding RNAs Required for Host Cell Colonization

scientific article

Conditional gene expression in Mycobacterium abscessus

scientific article

Contact with host cells induces a DNA repair system in pathogenic Neisseriae

scientific article

Cryoelectron Microscopy Reconstructions of the Pseudomonas aeruginosa and Neisseria gonorrhoeae Type IV Pili at Sub-nanometer Resolution

scientific article published in September 2017

Culture-negative pericarditis caused by Neisseria meningitidis serogroup C.

scientific article

Current ciprofloxacin usage in children hospitalized in a referral hospital in Paris

scientific article

Deciphering the microbiology of hidradenitis suppurativa: a step forward towards understanding an enigmatic inflammatory skin disease

scientific article

Decrease of hospital- and community-acquired bloodstream infections due to Streptococcus pneumoniae and Streptococcus pyogenes during the first year of the COVID-19 pandemic: A time-series analysis in Paris region

scientific article published in 2023

Detection and identification by PCR of a highly virulent phylogenetic subgroup among extraintestinal pathogenic Escherichia coli B2 strains

scientific article published on 9 February 2007

Detection of Panton–Valentine toxin in Staphylococcus aureus by mass spectrometry directly from colony: time has not yet come

scientific article published on 31 May 2010

Dramatic reduction of clindamycin plasma concentration in hidradenitis suppurativa patients treated with the rifampin-clindamycin combination

scientific article published on 01 January 2014

Efficacy of Rifampin-Moxifloxacin-Metronidazole Combination Therapy in Hidradenitis Suppurativa ⬇️

scientific article published on November 25, 2010

Efficacy of ertapenem in severe hidradenitis suppurativa: a pilot study in a cohort of 30 consecutive patients

scientific article

Endocarditis due to Neisseria mucosa: Case report and review of 21 cases

article

Environmental contamination with extended-spectrum β-lactamases: is there any difference between Escherichia coli and Klebsiella spp?

scientific article published on 9 February 2012

Epidemiological evidence for the role of the hemoglobin receptor, hmbR, in meningococcal virulence.

scientific article published on July 2009

Experimental Evidence of Bacterial Colonization of Human Coronary Microvasculature and Myocardial Tissue during Meningococcemia

scientific article published on August 2016

Extracellular bacterial pathogen induces host cell surface reorganization to resist shear stress

scientific article (publication date: February 2009)

Extraintestinal virulence is a coincidental by-product of commensalism in B2 phylogenetic group Escherichia coli strains.

scientific article published on 19 August 2007

Fulminant arterial vasculitis as an unusual complication of disseminated staphylococcal disease due to the emerging CC1 methicillin-susceptible Staphylococcus aureus clone: a case report

scientific article published on 03 April 2019

Genotypic and phenotypic modifications of Neisseria meningitidis after an accidental human passage

scientific article

Helicobacter bilis-Associated Suppurative Cholangitis in a Patient with X-Linked Agammaglobulinemia

scientific article published on 31 August 2017

High resolution typing of <i>Staphylococcus epidermidis</i> based on cgMLST to investigate the hospital spread of multidrug resistant clones

scientific article published on 16 December 2020

Horizontal transmission of Streptococcus pneumoniae in the surgical ward: a rare source of nosocomial wound infection

scientific article published on 20 July 2011

How do extracellular pathogens cross the blood-brain barrier?

scientific article

Identification of a novel transcriptional regulator involved in pilC1 regulation in Neisseria meningitidis.

scientific article

Identification of candidates for a subunit vaccine against extraintestinal pathogenic Escherichia coli

scientific article published on 4 December 2006

Identification of genes involved in Neisseria meningitidis colonization.

scientific article

Interaction of Neisseria meningitidis with a polarized monolayer of epithelial cells ⬇️

scientific article published on November 1, 1997

Interaction ofNeisseria meningitidiswith the Components of the Blood‐Brain Barrier Correlates with an Increased Expression of PilC ⬇️

scientific article published on November 1, 1997

Intracellular Survival of Staphylococcus aureus in Endothelial Cells: A Matter of Growth or Persistence

scientific article

Invasion of endothelial cells by Neisseria meningitidis requires cortactin recruitment by a phosphoinositide-3-kinase/Rac1 signalling pathway triggered by the lipo-oligosaccharide

scientific article

Invasion of the Central Nervous System by Neisseria meningitidis

scientific article published on January 1, 2001

Invasive meningococcal disease: a disease of the endothelial cells

scientific article published on 29 August 2014

Large-scale analysis of the meningococcus genome by gene disruption: resistance to complement-mediated lysis

scientific article

MALDI-TOF MS Andromas strategy for the routine identification of bacteria, mycobacteria, yeasts, Aspergillus spp. and positive blood cultures ⬇️

scientific article published on November 1, 2011

MALDI-TOF mass spectrometry tools for bacterial identification in clinical microbiology laboratory

scientific article

Matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of nonfermenting gram-negative bacilli isolated from cystic fibrosis patients

scientific article

Mechanism of meningeal invasion by Neisseria meningitidis ⬇️

scientific article

Mechanisms of meningeal invasion by a bacterial extracellular pathogen, the example of Neisseria meningitidis

scientific article published on 22 December 2009

Meningococcal adhesion suppresses proapoptotic gene expression and promotes expression of genes supporting early embryonic and cytoprotective signaling of human endothelial cells

scientific article published on October 2006

Meningococcal disease: A paradigm of type-IV pilus dependent pathogenesis

scientific article published on 01 April 2020

Meningococcal interaction to microvasculature triggers the tissular lesions of purpura fulminans

scientific article published on 9 July 2013

Meningococcal interactions with the host

scientific article published on 28 May 2009

Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium.

scientific article

Meningococcus Hijacks a β2-adrenoceptor/β-Arrestin pathway to cross brain microvasculature endothelium

scientific article published on December 2010

Microvilli-like structures are associated with the internalization of virulent capsulated Neisseria meningitidis into vascular endothelial cells.

scientific article published on March 2002

Molecular analysis and experimental virulence of French and North American Escherichia coli neonatal meningitis isolates: identification of a new virulent clone

scientific article published on 29 May 2003

Molecular interactions between Neisseria meningitidis and its human host

scientific article published on 13 June 2019

Neisseria meningitidis RTX proteins are not required for virulence in infant rats

scientific article

Neisseria meningitidis colonization of the brain endothelium and cerebrospinal fluid invasion

scientific article published on 24 December 2012

Neisseria meningitidis differentially controls host cell motility through PilC1 and PilC2 components of type IV Pili

scientific article

Neisseria meningitidis infection of human endothelial cells interferes with leukocyte transmigration by preventing the formation of endothelial docking structures

scientific article

Neisseria microarrays

scientific article published on 01 January 2002

New players in the toxin field: polymorphic toxin systems in bacteria

scientific article

Nontoxinogenic corynebacterium diphtheriae as a rare cause of native endocarditis in childhood

scientific article published on September 2010

Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths

scientific article published in January 2009

Pathogenesis of meningococcal purpura fulminans.

scientific article published on 9 March 2017

Pathogenesis of meningococcemia

scientific article published on June 2013

Pathogenic Neisseria meningitidis utilizes CD147 for vascular colonization

scientific article published on June 2014

Peripheral blood vessels are a niche for blood-borne meningococci.

scientific article

Phylogenetic and genomic diversity of human bacteremic Escherichia coli strains

scientific article

PilX, a pilus-associated protein essential for bacterial aggregation, is a key to pilus-facilitated attachment of Neisseria meningitidis to human cells.

scientific article

Pilus‐mediated adhesion of Neisseria meningitidis: the essential role of cell contact‐dependent transcriptional upregulation of the PilC1 protein ⬇️

scientific article published on June 1, 1998

Posttranslational modification of pili upon cell contact triggers N. meningitidis dissemination

scientific article published on February 2011

Propionibacterium acnes endocarditis in an adolescent boy suffering from a congenital cardiopathy

scientific article published in September 2007

Pulsative flushing as a strategy to prevent bacterial colonization of vascular access devices

scientific article published on 7 November 2014

Rapid epidemiological characterization of Neisseria meningitidis using polymerization chain reaction from biological samplings

scientific article published on October 25, 1997

Rapid identification of Staphylococci isolated in clinical microbiology laboratories by matrix-assisted laser desorption ionization-time of flight mass spectrometry

scientific article

Rapid identification of mycobacterial whole cells in solid and liquid culture media by matrix-assisted laser desorption ionization-time of flight mass spectrometry

scientific article

Real-time identification of bacteria and Candida species in positive blood culture broths by matrix-assisted laser desorption ionization-time of flight mass spectrometry

scientific article

Receptor recognition by meningococcal type IV pili relies on a specific complex N-glycan

scientific article published on 21 January 2020

Remission of chronic acne fulminans and severe hidradenitis suppurativa with targeted antibiotherapy.

scientific article published on 8 June 2019

Remission of refractory pyoderma gangrenosum, severe acne, and hidradenitis suppurativa (PASH) syndrome using targeted antibiotic therapy in 4 patients

scientific article published on November 2015

Representational difference analysis between Afa/Dr diffusely adhering Escherichia coli and nonpathogenic E. coli K-12.

scientific article

Ribosomal proteins as biomarkers for bacterial identification by mass spectrometry in the clinical microbiology laboratory

scientific article

Risk associated with a systematic search of extended-spectrum β-lactamase-producing Enterobacteriaceae

scientific article published on 11 October 2012

Risk factors associated with extended-spectrum β-lactamase-producing Enterobacteriaceae carriage at admission in an infant cohort at a tertiary teaching hospital in France

scientific article published on 7 March 2013

Salvage Strategy for Long-Term Central Venous Catheter-Associated Infections in Children

Sialic acid mediated mechanical activation of β2 adrenergic receptors by bacterial pili

scientific article published on 18 October 2019

Strategies used by bacterial pathogens to cross the blood-brain barrier

scientific article published on 28 October 2019

Strength of Neisseria meningitidis binding to endothelial cells requires highly-ordered CD147/β2-adrenoceptor clusters assembled by alpha-actinin-4.

scientific article

Structure of the Neisseria meningitidis Type IV pilus

scientific article

Successful identification of clinical dermatophyte and Neoscytalidium species by matrix-assisted laser desorption ionization-time of flight mass spectrometry

scientific article

Targeting Type IV pili as an antivirulence strategy against invasive meningococcal disease

scientific article published on 25 March 2019

The REP2 repeats of the genome of Neisseria meningitidis are associated with genes coordinately regulated during bacterial cell interaction

scientific article

The hypervariable region of meningococcal major pilin PilE controls the host cell response via antigenic variation.

scientific article published on 11 February 2014

The meningococcal minor pilin PilX is responsible for type IV pilus conformational changes associated with signaling to endothelial cells.

scientific article published on 9 July 2012

The microbiological landscape of anaerobic infections in Hidradenitis Suppurativa: a prospective metagenomic study

scientific article

The plasmid of Escherichia coli strain S88 (O45:K1:H7) that causes neonatal meningitis is closely related to avian pathogenic E. coli plasmids and is associated with high-level bacteremia in a neonatal rat meningitis model

scientific article published on 23 March 2009

The siderophore receptor IroN, but not the high-pathogenicity island or the hemin receptor ChuA, contributes to the bacteremic step of Escherichia coli neonatal meningitis

scientific article published on February 2004

Three homologues, including two membrane-bound proteins, of the disulfide oxidoreductase DsbA in Neisseria meningitidis: effects on bacterial growth and biogenesis of functional type IV pili

scientific article published on 21 April 2004

Transketolase of Staphylococcus aureus in the Control of Master Regulators of Stress Response During Infection

scientific article published on 01 November 2019

Two strikingly different signaling pathways are induced by meningococcal type IV pili on endothelial and epithelial cells

scientific article

Type IV pilus biogenesis in Neisseria meningitidis: PilW is involved in a step occurring after pilus assembly, essential for fibre stability and function

article by Etienne Carbonnelle et al published 12 October 2004 in Molecular Microbiology

Type IV pilus biogenesis in Neisseria meningitidis: PilW is involved in a step occurring after pilus assembly, essential for fibre stability and function

article by Etienne Carbonnelle et al published January 2005 in Molecular Microbiology

Type IV pilus retraction in pathogenic Neisseria is regulated by the PilC proteins.

scientific article

[Extension of beta-lactamases producing bacteria is a worldwide concern].

scientific article

[Meningococcus purpura fulminans, a partially solved mystery]

scientific article published on 01 December 2018

[The trick of the meningococcus]

scientific article published on 01 January 2010

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